Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody

Nature Medicine

Volumn 11, Issue 11, 2005, Pages 1250-1255

  Sharkey, Robert M ^a   Cardillo, Thomas M ^b   Rossi, Edmund A ^c   Chang, Chien Hsing ^c   Karacay, Habibe ^a   McBride, William J ^b   Hansen, Hans J ^b   Horak, Ivan D ^b   Goldenberg, David M ^a  

^a CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

^b IMMUNOMEDICS INC   (United States)

^c IBC Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISPECIFIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; HAPTEN; PEPTIDE; TECHNETIUM 99M; TRACER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; BLOOD; CANCER DIAGNOSIS; COLON CARCINOMA; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG TARGETING; FEMALE; HUMAN; HUMAN TISSUE; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TIME; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, BISPECIFIC; CARCINOEMBRYONIC ANTIGEN; COLONIC NEOPLASMS; FEMALE; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, NUDE; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; RADIOIMMUNOTHERAPY; RADIONUCLIDE IMAGING; TECHNETIUM; TIME FACTORS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; MUS MUSCULUS;

EID: 30744455270     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1322     Document Type: Article

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