Disruption of gap junctions attenuates aminoglycoside-elicited renal tubular cell injury

British Journal of Pharmacology

Volumn 160, Issue 8, 2010, Pages 2055-2068

  Yao, Jian ^a   Huang, Tao ^a   Fang, Xin ^a   Chi, Yuan ^a   Zhu, Ying ^a   Wan, Yigang ^b   Matsue, Hiroyuki ^c   Kitamura, Masanori ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Akt; aminoglycoside; connexin 43; cytotoxicity; gap junction; gap junctional intercellular communication; renal tubular epithelial cells; glycyrrhetinic acid

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC G 418; BETA ACTIN; CONNEXIN 43; DYE; GLYCYRRHETINIC ACID; HYGROMYCIN; PROTEIN KINASE B; SMALL INTERFERING RNA; AMINOGLYCOSIDE; ANDROSTANE DERIVATIVE; CINNAMIC ACID DERIVATIVE; GENTAMICIN; HYBRID PROTEIN; HYGROMYCIN B; PROTEIN KINASE INHIBITOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; GAP JUNCTION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; KIDNEY TUBULE DAMAGE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; CELL PROTECTION; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; KIDNEY TUBULE; LLC PK1 CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RAT; RNA INTERFERENCE; SWINE; TOXICITY;

AMINOGLYCOSIDES; ANDROSTADIENES; ANIMALS; BLOTTING, WESTERN; CELL COMMUNICATION; CELL SURVIVAL; CINNAMATES; CONNEXIN 43; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GAP JUNCTIONS; GENTAMICINS; GLYCYRRHETINIC ACID; HYGROMYCIN B; KIDNEY TUBULES; LLC-PK1 CELLS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SWINE; TRANSFECTION;

EID: 77954874908     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00860.x     Document Type: Article

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