Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells

Journal of Biological Chemistry

Volumn 278, Issue 32, 2003, Pages 30005-30014

  Qin, Hong ^d   Shao, Qing ^a   Igdoura, Suleiman A ^b   Alaoui Jamali, Moulay A ^c   Laird, Dale W ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; ELECTRON MICROSCOPY; PROTEINS;

PROTEASOMAL DEGRADATION;

BIOCHEMISTRY;

BREFELDIN A; CONNEXIN 43; LACTACYSTIN; PROTEASOME;

ARTICLE; CELL COMMUNICATION; CELL LINE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GAP JUNCTION; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; INTERNALIZATION; LYSOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SECRETORY VESICLE; TUMOR CELL; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; BLOTTING, WESTERN; BREAST NEOPLASMS; BREFELDIN A; CELL COMMUNICATION; CELL MEMBRANE; CONNEXIN 43; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; GAP JUNCTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; LYSOSOMES; MAMMARY NEOPLASMS, ANIMAL; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SYNTHESIS INHIBITORS; PROTEIN TRANSPORT; RATS; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0042030808     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300614200     Document Type: Article

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