The phosphoinositide-3 kinase γ-Akt pathway mediates renal tubular injury in cisplatin nephrotoxicity

Kidney International

Volumn 73, Issue 4, 2008, Pages 430-445

  Kuwana, H ^a   Terada, Y ^a   Kobayashi, T ^a   Okado, T ^a   Penninger, J M ^b   Irie Sasaki, J ^c   Sasaki, T ^c   Sasaki, S ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^c AKITA UNIVERSITY   (Japan)

Author keywords

AKI; Apoptosis; Caspase; Renal tubules

Indexed keywords

CISPLATIN; CREATININE; DNA FRAGMENT; HISTONE; NITROGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PROTEIN KINASE B; UNCLASSIFIED DRUG; UREA;

ACUTE DISEASE; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; KIDNEY DYSFUNCTION; KIDNEY TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE DAMAGE; KNOCKOUT MOUSE; LETHAL DOSE; MALE; MOUSE; MOUSE STRAIN; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UPREGULATION; UREA NITROGEN BLOOD LEVEL; WILD TYPE;

EID: 38749098681     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002702     Document Type: Article

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