Preparation, safety, pharmacokinetics, and pharmacodynamics of liposomes containing brucea javanica oil

AAPS PharmSciTech

Volumn 11, Issue 2, 2010, Pages 878-884

  Cui, Yanxia ^a   Wu, Zimei ^b   Liu, Xiaoxu ^a   Ni, Rui ^a   Zhu, Xuanxuan ^c   Ma, Lulu ^a   Liu, Jianping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Antitumor; Brucea javanica oil (BJO); Liposomes; Pharmacodynamics; Pharmacokinetics

Indexed keywords

BRUCEA JAVANICA EXTRACT; BRUCEA JAVANICA OIL; LIPOSOME; OLEIC ACID; UNCLASSIFIED DRUG; DRUG VEHICLE; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HALF LIFE; DRUG SAFETY; DRUG SYNTHESIS; EMULSION; FEMALE; HUMAN; HUMAN CELL; IC 50; LETHAL DOSE; LEWIS CARCINOMA; LIGHT SCATTERING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; WEIGHT REDUCTION; ZETA POTENTIAL; ANIMAL; BRUCEA; CARCINOMA, HEPATOCELLULAR; CHEMISTRY; LD 50; LIVER NEOPLASMS; METABOLISM; SURVIVAL RATE; TOXICITY; TREATMENT OUTCOME;

ANIMALS; BRUCEA; CARCINOMA, HEPATOCELLULAR; FEMALE; LETHAL DOSE 50; LIPOSOMES; LIVER NEOPLASMS; MALE; MICE; PLANT OILS; RATS; SURVIVAL RATE; TREATMENT OUTCOME; VEHICLES; PHARMACEUTICAL VEHICLES;

EID: 77954818815     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9454-4     Document Type: Article

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