Reversal of multidrug resistance and inhibition of DNA topoisomerase II by emulsion of seed oil of Brucea Javanica

Chinese Pharmacological Bulletin

Volumn 17, Issue 5, 2001, Pages 534-539

  Tang, T ^a   Meng, L H ^a   Chen, L J ^a   Ding, J ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Brucea Javanica; DNA topoisomerase; Multidrug resistance

Indexed keywords

BRUCEA JAVANICA EXTRACT; DNA TOPOISOMERASE (ATP HYDROLYSING); PROTEIN PBR322; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PLANT SEED; PROTEIN FOLDING; TUMOR CELL;

EID: 0034763342     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Multidrug resistance and its reversal
2. Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro
3. Reversal of multidrug resistance phenotype by surfactants: Relationship to membrane lipid fluidity
4. DNA Topoisomerases
5. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
6. Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells
7. Clinical reversal of drug resistance
8. Bepridil in combination with anthracyclines to reverse anthracycline resistance in cancer patients
9. DNA topoisomerase poisons as antitumor drugs