Disruption of stromal-derived factor-1/chemokine receptor 4 by simvastatin

Iranian Cardiovascular Research Journal

Volumn 4, Issue 1, 2010, Pages 1-7

  Masori, M ^a,b   Jalili, A ^b   Nakaya, Y ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KURDISTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Atherosclerosis; CXCR4; Monocytes; SDF 1; Simvastatin

Indexed keywords

CHEMOKINE RECEPTOR CCR4; SIMVASTATIN; STROMAL CELL DERIVED FACTOR 1;

ADHESION; ARTICLE; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONOCYTE; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 77954775772     PISSN: 1735885X     EISSN: 17358868     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Libby P. Inflammation and atherosclerosis. Nature 2002;420:868-74.[12490960]
2. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685-95.[15843671]
3. Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 2006;6:508-19.[16778830]
4. Braunersreuther V, Mach F, Steffens S. The specific role of chemokines in atherosclerosis. Thromb Haemost 2007;97:714-21. [17479181]
5. Shimada K. Immune system and atherosclerotic disease: heterogeneity of Aleukocyte subsets participating in the pathogenesis of atherosclerosis. Circ J 2009;73:994-1001. [19430164]
6. Bobryshev YV. Monocyte recruitment and foam cell formation in atherosclerosis. Micron 2006; 37:208-22. [16360317]
7. Boring L, Gosling J, Cleary M, Charo IF. Decreased lesion formation in CCR2-/mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998;394:894-7. [9732872]
8. Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest 1998;101:353-63. [9435307]
9. Lesnik P, Haskell CA, Charo IF. Deceased atherosclerosis in CX 3CR1-/ mice reveals a role for fractalkine in atherogenesis. J Clin Invest 2003;111:333-40. [12569158]
10. Blades MC, Ingegnoli F, Wheller SK, et al. Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice. Arthritis Rheum 2002;46:824-36. [11920421]
11. Nagase H, Miyamasu M, Yamaguchi M, et al. Cytokine-mediated regulation of CXCR4 expression in human neutrophils. J Leukoc Biol 2002;71:711-7. [11927659]
12. Abi-Younes S, Sauty A, Mach F, Sukhova GK, Libby P, Luster AD. The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques. Circ Res 2000;86:131-8. [10666407]
13. Takahashi K, Shimokado K, Yoshida M. SDF-1-induced adhesion of monocytes to vascular endothelium is modulated by azelnidipine via protein kinase C inhibition. Eur J Pharmacol 2006;552:162-9. [17067573]
14. Tobert JA. Lovastatin and beyond: the history of the HMG CoA reductase inhibitors. Nat Rev Drug Discov 2003;2:517-26. [12815379]
15. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998;339:1349-57. [9841303]
16. Zhou Q, Liao JK. Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy. Curr Pharm Des 2009;15:467-78. [19199975]
17. Martin JH, Mangiafico S, Kelly DJ. Role of statins in diabetes complications. Curr Diabetes Rev 2009;5:165-70. [19689251]
18. Chao-Yung Wang, Ping-Yen Liu, and James K. Liao. Pleiotropic effects of statin therapy: molecular mechanisms and clinical results. Trends Mol Med 2008;14:37-44. [18068482]
19. Soma MR, Donetti E, Parolini C, et al. HMG CoA reductase inhibitors: in vivo effects on carotid intimal thickening in normocholester normocholesterolemic rabbits. Arterioscl Thromb 1993;13:571-8. [8466892]
20. Wong B, Lumma WC, Smith AM, Sisko JT, Wright SD, Cai TQ. Statins suppress THP-1 cell migration and secretion of matrix me-talloproteinase 9 by inhibiting geranylgeranylation. J Leukoc Biol 2001;69:959-62. [11404382]
21. Breland UM, Halvorsen B, Hol J, et al. A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins. Arterioscler Thromb Vasc Biol 2008;28:1005-11. [18276907]
22. Smith C, Halvorsen B, Otterdal K. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins. Cardiovasc Res 2008;79:195-203. [18339644]
23. de Almeida MC, Silva AC, Barral A, Barral Netto M. A simple method for human peripheral blood monocyte isolation. Mem Inst Oswaldo Cruz 2000;95:221-3. [10733742]
24. Yoshida M, Sawada T, Ishii H, et al. Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism. Arterioscler Thromb Vasc Biol 2001;21:1165-71. [11451746]
25. Pellegrino A, Ria R, Di Pietro G, et al. Bone marrow endothelial cells in multiple myeloma secrete CXC-chemokines that mediate interactions with plasma cells. Br J Haematol 2005;129:248-56. [15813853]
26. Weber C, Schober A, Zernecke A. Chemokines: key regulators of mononuclear cellrecruitment in atherosclerotic vascular disease. Arterioscler Thromb Vasc Biol 2004;24:1997-2008. [15319268]
27. Issekutz AC, Issekutz TB. Monocyte migration to arthritis in the rat utilizes bothCD11/CD18 and very late activation. J Exp Med 1995;181:1197-203. [7532681]
28. Zlotnik A. New insights on the role of CXCR4 in cancer metastasis. J Pathol 2008;215:211-3.
29. Burger JA, Peled A. CXCR4 antagonists: targeting the microenvironment in leukemiaand other cancers. Leukemia 2009;23:43-52. [18987663]
30. Haydena JM, Brachovaa L, Higgins K, et al. Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol. J Lipid Res 2002;43:26-35. [11792719]
31. Gupta SK, Pillarisetti K, Lysko PG. Modulation of CXCR4 expression and SDF-1alphafunctional activity during differentiation of human monocytes and macrophages. J Leukoc Biol 1999;66:135-43. [10411001]
32. Papadopoulou C, Corrigall V, Taylor PR, Poston RN. The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to humanatherosclerotic plaques. Cytokine 2008;43:181-6. [18579408]
33. Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest 1998;101:353-63. [9435307]
34. Méndez-Ferrer S, Frenette PS. Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment. Ann N Y Acad Sci 2007;1116:392-413. [18083941]
35. Petit I, Szyper-Kravitz M, Nagler A et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol 2002;3:687-94. [12068293]