Impaired mitochondrial oxidative phosphorylation in multiple insulin-sensitive tissues of humans with type 2 diabetes mellitus

Journal of International Medical Research

Volumn 38, Issue 3, 2010, Pages 769-781

  Wang, M ^a   Wang, X C ^a   Zhang, Z Y ^a   Mou, B ^a   Hu, R M ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

DNA chip; Gene expression profile; Mitochondrial DNA; Oxidative phosphorylation; Transcriptional co factors; Type 2 diabetes mellitus

Indexed keywords

MESSENGER RNA; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; HEAT SHOCK PROTEIN; INSULIN; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETOGENESIS; DNA CONTENT; DNA MICROARRAY; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; UPREGULATION; ADIPOSE TISSUE; GENE EXPRESSION; GENETICS; LIVER; METABOLISM; MIDDLE AGED; MITOCHONDRION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOSE TISSUE; AGED; DIABETES MELLITUS, TYPE 2; DNA, MITOCHONDRIAL; FEMALE; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MIDDLE AGED; MITOCHONDRIA; MUSCLE, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77954765768     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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