Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury

JARO - Journal of the Association for Research in Otolaryngology

Volumn 11, Issue 2, 2010, Pages 223-234

  Sato, Eisuke ^a   Shick, H Elizabeth ^b   Ransohoff, Richard M ^b   Hirose, Keiko ^c  

^a NAGOYA UNIVERSITY   (Japan)

^b LERNER RESEARCH INSTITUTE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aminoglycoside; B6.CAST Cdh23 ahl+ mice; Bone marrow chimeras; CX3CR1; Kanamycin; Macrophage; Ototoxicity

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; KANAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL COUNT; CELL DEATH; CELL SURVIVAL; CHIMERA; COCHLEA; CONTROLLED STUDY; EMBRYO; EVOKED BRAIN STEM AUDITORY RESPONSE; FUNCTIONAL ASSESSMENT; GENE DELETION; GENETIC SUSCEPTIBILITY; HAIR CELL; HEARING LOSS; HETEROZYGOSITY; INFLAMMATORY CELL; INNER EAR; IRRADIATION; LEUKOCYTE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; ORGAN INJURY; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; AUDITORY THRESHOLD; BONE MARROW; CELL SURVIVAL; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS; KANAMYCIN; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PREGNANCY; PROTEIN SYNTHESIS INHIBITORS; RADIATION CHIMERA; RECEPTORS, CHEMOKINE;

EID: 77954761093     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10162-009-0198-3     Document Type: Article

References (39)

1. AJAMI B, BENNETT JL, KRIEGER C, TETZLAFF W, ROSSI FM (2007) Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci 10:1538-1543.
2. BHAVE SA, OESTERLE EC, COLTRERA MD (1998) Macrophage and microglia-like cells in the avian inner ear. J Comp Neurol 398:241-256.
3. BROWNING GG, NORTHROP R, CORTESE R (1982) Selective destruction of the outer hair cells in the chinchilla. Clin Otolaryngol Allied Sci 7:3-9.
4. CARDONA AE, PIORO EP, SASSE ME, KOSTENKO V, CARDONA SM, DIJKSTRA IM, HUANG D, KIDD G, DOMBROWSKI S, DUTTA R, LEE JC, COOK DN, JUNG S, LIRA SA, LITTMAN DR, RANSOHOFF RM (2006) Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci 9:917-924.
5. CHEN CS, SAUNDERS JC (1983) The sensitive period for ototoxicity of kanamycin in mice: morphological evidence. Arch Otorhinolaryngol 238:217-223.
6. COTTER R, WILLIAMS C, RYAN L, ERICHSEN D, LOPEZ A, PENG H, ZHENG J (2002) FRACTALKINE (CX3CL1) AND brain inflammation: implications for HIV-1-associated dementia. J Neurovirology 8:585-598.
7. CUADROS MA, SANTOS AM, MARTIN-OLIVA D, CALVENTE R, TASSI M, MARIN-TEVA JL, NAVASCUES J (2006) Specific immunolabeling of brain macrophages and microglial cells in the developing and mature chick central nervous system. J Histochem Cytochem 54:727-738.
8. DENES A, FERENCZI S, HALASZ J, KORNYEI Z, KOVACS KJ (2008) Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. J Cereb Blood Flow Metab 28:1707-1721.
9. EHRET G (1983) Peripheral anatomy and physiology II. In: Willott J (ed) The auditory psychobiology of the mouse. Springfield, IL: Charles C. Thomas, p 169-200.
10. FORGE A, FRADIS M (1985) Structural abnormalities in the stria vascularis following chronic gentamicin treatment. Hear Res 20:233-244. (Pubitemid 16174879)
11. FREDELIUS L, RASK-ANDERSEN H (1990) The role of macrophages in the disposal of degeneration products within the organ of corti after acoustic overstimulation. Acta Otolaryngol 109:76-82.
12. GOODYEAR RJ, GALE JE, RANATUNGA KM, KROS CJ, RICHARDSON GP (2008) Aminoglycoside-induced phosphatidylserine externalization in sensory hair cells is regionally restricted, rapid, and reversible. J Neurosci 28:9939-9952.
13. HARRISON JK, JIANG Y, CHEN S, XIA Y, MACIEJEWSKI D, MCNAMARA RK, STREIT WJ, SALAFRANCA MN, ADHIKARI S, THOMPSON DA, BOTTI P, BACON KB, FENG L (1998) Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci USA 95:10896-10901.
14. HENRY KR, CHOLE RA, MCGINN MD, FRUSH DP (1981) Increased ototoxicity in both young and old mice. Arch Otolaryngol 107:92-95.
15. HIROSE K, DISCOLO CM, KEASLER JR, RANSOHOFF R (2005) Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma. J Comp Neurol 489:180-194.
16. JABBA SV, OELKE A, SINGH R, MAGANTI RJ, FLEMING S, WALL SM, EVERETT LA, GREEN ED, WANGEMANN P (2006) Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model. BMC Med 4:37.
17. JIANG H, SHA SH, FORGE A, SCHACHT J (2006) Caspase-independent pathways of hair cell death induced by kanamycin in vivo. Cell Death Differ 13:20-30.
18. JUNG S, ALIBERTI J, GRAEMMEL P, SUNSHINE MJ, KREUTZBERG GW, SHER A, LITTMAN DR (2000) Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 20:4106-4114.
19. LADRECH S, WANG J, SIMONNEAU L, PUEL JL, LENOIR M (2007) Macrophage contribution to the response of the rat organ of Corti to amikacin. J Neurosci Res 85:1970-1979.
20. LAURO C, DI ANGELANTONIO S, CIPRIANI R, SOBRERO F, ANTONILLI L, BRUSADIN V, RAGOZZINO D, LIMATOLA C (2008) Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. J Immunol 180:7590-7596.
21. LEE JE, NAKAGAWA T, KIM TS, IGUCHI F, ENDO T, KITA T, MURAI N, NAITO Y, LEE SH, ITO J (2004) Signaling pathway for apoptosis of vestibular hair cells of mice due to aminoglycosides. Acta Otolaryngol Suppl, pp 69-74.
22. LIMATOLA C, LAURO C, CATALANO M, CIOTTI M, BERTOLLINI C, DIANGELANTONIO S, RAGOZZINO D, EUSEBI F (2005a) Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity. J Neurosci 166:19-28.
23. LIMATOLA C, LAURO C, CATALANO M, CIOTTI MT, BERTOLLINI C, DI ANGELANTONIO S, RAGOZZINO D, EUSEBI F (2005b) Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity. J Neuroimmunol 166:19-28.
24. MATSUI JI, HAQUE A, HUSS D, MESSANA EP, ALOSI JA, ROBERSON DW, COTANCHE DA, DICKMAN JD, WARCHOL ME (2003) Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo. J Neurosci 23:6111-6122.
25. NAKAGAWA T, KIM TS, MURAI N, ENDO T, IGUCHI F, TATEYA I, YAMAMOTO N, NAITO Y, ITO J (2003) A novel technique for inducing local inner ear damage. Hear Res 176:122-127.
26. NEUMANN J, GUNZER M, GUTZEIT HO, ULLRICH O, REYMANN KG, DINKEL K (2006) Microglia provide neuroprotection after ischemia. FASEB J 20:714-716.
27. NGUYEN MD, D'AIGLE T, GOWING G, JULIEN JP, RIVEST S (2004) Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. J Neurosci 24:1340-1349.
28. NOBEN-TRAUTH K, ZHENG QY, JOHNSON KR (2003) Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat Genet 35:21-23.
29. OESTERLE EC, CAMPBELL S, TAYLOR RR, FORGE A, HUME CR (2008) Sox2 and JAGGED1 expression in normal and drug-damaged adult mouse inner ear. J Assoc Res Otolaryngol 9:65-89.
30. SATO E, SHICK HE, RANSOHOFF RM, HIROSE K (2008) Repopulation of cochlear macrophages in murine hematopoietic progenitor cell chimeras: the role of CX3CR1. J Comp Neurol 506:930-942.
31. SAUTTER NB, SHICK EH, RANSOHOFF RM, CHARO IF, HIROSE K (2006) CC chemokine receptor 2 is protective against noise-induced hair cell death: studies in CX3CR1(+/GFP) mice. J Assoc Res Otolaryngol 7:361-372.
32. SO H, KIM H, KIM Y, KIM E, PAE HO, CHUNG HT, KIM HJ, KWON KB, LEE KM, LEE HY, MOON SK, PARK R (2008) Evidence that cisplatininduced auditory damage is attenuated by downregulation of pro-inflammatory cytokines via Nrf2/HO-1. J Assoc Res Otolaryngol 9:290-306.
33. TABUCHI K, PAK K, CHAVEZ E, RYAN AF (2007) Role of inhibitor of apoptosis protein in gentamicin-induced cochlear hair cell damage. Neuroscience 149:213-222.
34. TALEB M, BRANDON CS, LEE FS, LOMAX MI, DILLMANN WH, CUNNINGHAM LL (2008) HSP70 inhibits aminoglycoside-induced hair cell death and is necessary for the protective effect of heat shock. J Assoc Res Otolaryngol 9:277-289.
35. TALEB M, BRANDON CS, LEE FS, HARRIS KC, DILLMANN WH, CUNNINGHAM LL (2009) HSP70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death. Cell Stress Chaperones 14:427-437.
36. TAYLOR RR, NEVILL G, FORGE A (2008) Rapid hair cell loss: a mouse model for cochlear lesions. J Assoc Res Otolaryngol 9:44-64.
37. WARCHOL ME (1997) Macrophage activity in organ cultures of the avian cochlea: demonstration of a resident population and recruitment to sites of hair cell lesions. J Neurobiol 33:724-734.
38. WARCHOL ME (1999) Immune cytokines and dexamethasone influence sensory regeneration in the avian vestibular periphery. J Neurocytol 28:889-900.
39. WU WJ, SHA SH, MCLAREN JD, KAWAMOTO K, RAPHAEL Y, SCHACHT J (2001) Aminoglycoside ototoxicity in adult CBA, C57BL and BALB mice and the Sprague-Dawley rat. Hear Res 158:165-178.