-
1
-
-
0028169992
-
HNF-3 beta is essential for node and notochord formation in mouse development
-
Ang SL, Rossant J (1994) HNF-3 beta is essential for node and notochord formation in mouse development. Cell 78:561-574.
-
(1994)
Cell
, vol.78
, pp. 561-574
-
-
Ang, S.L.1
Rossant, J.2
-
2
-
-
0030050751
-
A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain
-
Ang SL, Jin O, Rhinn M, Daigle N, Stevenson L, Rossant J (1996) A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development 122:243-252.
-
(1996)
Development
, vol.122
, pp. 243-252
-
-
Ang, S.L.1
Jin, O.2
Rhinn, M.3
Daigle, N.4
Stevenson, L.5
Rossant, J.6
-
3
-
-
18344389337
-
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 coactivator
-
Bamforth SD, Braganca J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S (2001) Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 coactivator. Nat Genet 29:469-474.
-
(2001)
Nat Genet
, vol.29
, pp. 469-474
-
-
Bamforth, S.D.1
Braganca, J.2
Eloranta, J.J.3
Murdoch, J.N.4
Marques, F.I.5
Kranc, K.R.6
Farza, H.7
Henderson, D.J.8
Hurst, H.C.9
Bhattacharya, S.10
-
4
-
-
16544377641
-
Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway
-
Bamforth SD, Braganca J, Farthing CR, Schneider JE, Broadbent C, Michell AC, Clarke K, Neubauer S, Norris D, Brown NA, Anderson RH, Bhattacharya S (2004) Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet 36:1189-1196.
-
(2004)
Nat Genet
, vol.36
, pp. 1189-1196
-
-
Bamforth, S.D.1
Braganca, J.2
Farthing, C.R.3
Schneider, J.E.4
Broadbent, C.5
Michell, A.C.6
Clarke, K.7
Neubauer, S.8
Norris, D.9
Brown, N.A.10
Anderson, R.H.11
Bhattacharya, S.12
-
5
-
-
0036678117
-
Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia
-
Bartoloni L, Blouin JL, Pan Y, Gehrig C, Maiti AK, Scamuffa N, Rossier C, Jorissen M, Armengot M, Meeks M, Mitchison HM, Chung EM, Delozier-Blanchet CD, Craigen WJ, Antonarakis SE (2002) Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia. Proc Natl Acad Sci USA 99:10282-10286.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10282-10286
-
-
Bartoloni, L.1
Blouin, J.L.2
Pan, Y.3
Gehrig, C.4
Maiti, A.K.5
Scamuffa, N.6
Rossier, C.7
Jorissen, M.8
Armengot, M.9
Meeks, M.10
Mitchison, H.M.11
Chung, E.M.12
Delozier-Blanchet, C.D.13
Craigen, W.J.14
Antonarakis, S.E.15
-
6
-
-
35648954659
-
The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning
-
Beckers A, Alten L, Viebahn C, Andre P, Gossler A (2007) The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning. Proc Natl Acad Sci USA 104:15765-15770.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15765-15770
-
-
Beckers, A.1
Alten, L.2
Viebahn, C.3
Andre, P.4
Gossler, A.5
-
7
-
-
0026345053
-
Genetically determined variation in the azygos vein in the mouse
-
Biddle FG, Jung JD, Eales BA (1991) Genetically determined variation in the azygos vein in the mouse. Teratology 44:675-683.
-
(1991)
Teratology
, vol.44
, pp. 675-683
-
-
Biddle, F.G.1
Jung, J.D.2
Eales, B.A.3
-
8
-
-
33847006616
-
Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo
-
Blum M, Andre P, Muders K, Schweickert A, Fischer A, Bitzer E, Bogusch S, Beyer T, van Straaten HW, Viebahn C (2007) Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo. Differentiation 75:133-146.
-
(2007)
Differentiation
, vol.75
, pp. 133-146
-
-
Blum, M.1
Andre, P.2
Muders, K.3
Schweickert, A.4
Fischer, A.5
Bitzer, E.6
Bogusch, S.7
Beyer, T.8
Van Straaten, H.W.9
Viebahn, C.10
-
9
-
-
0037106188
-
Nodal activity in the node governs left-right asymmetry
-
Brennan J, Norris DP, Robertson EJ (2002) Nodal activity in the node governs left-right asymmetry. Genes Dev 16:2339-2344.
-
(2002)
Genes Dev
, vol.16
, pp. 2339-2344
-
-
Brennan, J.1
Norris, D.P.2
Robertson, E.J.3
-
10
-
-
0005515655
-
Smad5 is essential for left-right asymmetry in mice
-
Chang H, Zwijsen A, Vogel H, Huylebroeck D, Matzuk MM (2000) Smad5 is essential for left-right asymmetry in mice. Dev Biol 219:71-78.
-
(2000)
Dev Biol
, vol.219
, pp. 71-78
-
-
Chang, H.1
Zwijsen, A.2
Vogel, H.3
Huylebroeck, D.4
Matzuk, M.M.5
-
11
-
-
42149159492
-
Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal
-
Cohen ED, Tian Y, Morrisey EE (2008) Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 135:789-798.
-
(2008)
Development
, vol.135
, pp. 789-798
-
-
Cohen, E.D.1
Tian, Y.2
Morrisey, E.E.3
-
12
-
-
26644460824
-
Vertebrate Smoothened functions at the primary cilium
-
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF (2005) Vertebrate Smoothened functions at the primary cilium. Nature 437:1018-1021.
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
13
-
-
0038640316
-
The Role of Pitx2 during cardiac development. Linking left-right signaling and congenital heart diseases
-
Franco D, Campione M (2003) The Role of Pitx2 during cardiac development. Linking left-right signaling and congenital heart diseases. Trends Cardiovasc Med 13:157-163.
-
(2003)
Trends Cardiovasc Med
, vol.13
, pp. 157-163
-
-
Franco, D.1
Campione, M.2
-
14
-
-
0033581923
-
A role of the cryptic gene in the correct establishment of the left-right axis
-
Gaio U, Schweickert A, Fischer A, Garratt AN, Muller T, Ozcelik C, Lankes W, Strehle M, Britsch S, Blum M, Birchmeier C (1999) A role of the cryptic gene in the correct establishment of the left-right axis. Curr Biol 9:1339-1342.
-
(1999)
Curr Biol
, vol.9
, pp. 1339-1342
-
-
Gaio, U.1
Schweickert, A.2
Fischer, A.3
Garratt, A.N.4
Muller, T.5
Ozcelik, C.6
Lankes, W.7
Strehle, M.8
Britsch, S.9
Blum, M.10
Birchmeier, C.11
-
15
-
-
49249132211
-
Tbx6 regulates left/right patterning in mouse embryos through effects on Nodal cilia and periNodal signaling
-
Hadjantonakis AK, Pisano E, Papaioannou VE (2008) Tbx6 regulates left/right patterning in mouse embryos through effects on Nodal cilia and periNodal signaling. PLoS ONE 3:e2511.
-
(2008)
PLoS ONE
, vol.3
-
-
Hadjantonakis, A.K.1
Pisano, E.2
Papaioannou, V.E.3
-
17
-
-
0036301401
-
Patterning the vertebrate heart
-
Harvey RP (2002) Patterning the vertebrate heart. Nat Rev Genet 3:544-556.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 544-556
-
-
Harvey, R.P.1
-
18
-
-
37449010541
-
The multifaceted role of Notch in cardiac development and disease
-
High FA, Epstein JA (2008) The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 9:49-61.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 49-61
-
-
High, F.A.1
Epstein, J.A.2
-
19
-
-
33646204913
-
Nodal flow and the generation of left-right asymmetry
-
Hirokawa N, Tanaka Y, Okada Y, Takeda S (2006) Nodal flow and the generation of left-right asymmetry. Cell 125:33-45.
-
(2006)
Cell
, vol.125
, pp. 33-45
-
-
Hirokawa, N.1
Tanaka, Y.2
Okada, Y.3
Takeda, S.4
-
20
-
-
0036316447
-
Development of pharyngeal arch arteries in early mouse embryo
-
Hiruma T, Nakajima Y, Nakamura H (2002) Development of pharyngeal arch arteries in early mouse embryo. J Anat 201: 15-29.
-
(2002)
J Anat
, vol.201
, pp. 15-29
-
-
Hiruma, T.1
Nakajima, Y.2
Nakamura, H.3
-
21
-
-
60549107691
-
FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1
-
Hong SK, Dawid IB (2009) FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1. Proc Natl Acad Sci USA 106:2230-2235.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2230-2235
-
-
Hong, S.K.1
Dawid, I.B.2
-
22
-
-
0035873224
-
FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse
-
Hoodless PA, Pye M, Chazaud C, Labbe E, Attisano L, Rossant J, Wrana JL (2001) FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse. Genes Dev 15:1257-1271.
-
(2001)
Genes Dev
, vol.15
, pp. 1257-1271
-
-
Hoodless, P.A.1
Pye, M.2
Chazaud, C.3
Labbe, E.4
Attisano, L.5
Rossant, J.6
Wrana, J.L.7
-
23
-
-
7544219964
-
BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo
-
Kishigami S, Yoshikawa S, Castranio T, Okazaki K, Furuta Y, Mishina Y (2004) BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo. Dev Biol 276:185-193.
-
(2004)
Dev Biol
, vol.276
, pp. 185-193
-
-
Kishigami, S.1
Yoshikawa, S.2
Castranio, T.3
Okazaki, K.4
Furuta, Y.5
Mishina, Y.6
-
24
-
-
0038274073
-
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
-
Krebs LT, Iwai N, Nonaka S, Welsh IC, Lan Y, Jiang R, Saijoh Y, O'Brien TP, Hamada H, Gridley T (2003) Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. Genes Dev 17:1207-1212.
-
(2003)
Genes Dev
, vol.17
, pp. 1207-1212
-
-
Krebs, L.T.1
Iwai, N.2
Nonaka, S.3
Welsh, I.C.4
Lan, Y.5
Jiang, R.6
Saijoh, Y.7
O'Brien, T.P.8
Hamada, H.9
Gridley, T.10
-
25
-
-
57149115955
-
Morphogenesis of the node and notochord: the cellular basis for the establishment and maintenance of left-right asymmetry in the mouse
-
Lee JD, Anderson KV (2008) Morphogenesis of the node and notochord: the cellular basis for the establishment and maintenance of left-right asymmetry in the mouse. Dev Dyn 237:3464- 3476.
-
(2008)
Dev Dyn
, vol.237
, pp. 3464-3476
-
-
Lee, J.D.1
Anderson, K.V.2
-
26
-
-
0029089617
-
A molecular pathway determining left-right asymmetry in chick embryogenesis
-
Levin M, Johnson RL, Stern CD, Kuehn M, Tabin C (1995) A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82:803-814.
-
(1995)
Cell
, vol.82
, pp. 803-814
-
-
Levin, M.1
Johnson, R.L.2
Stern, C.D.3
Kuehn, M.4
Tabin, C.5
-
27
-
-
0036849873
-
Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions
-
Liu C, Liu W, Palie J, Lu MF, Brown NA, Martin JF (2002) Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development 129:5081-5091.
-
(2002)
Development
, vol.129
, pp. 5081-5091
-
-
Liu, C.1
Liu, W.2
Palie, J.3
Lu, M.F.4
Brown, N.A.5
Martin, J.F.6
-
28
-
-
48749095188
-
Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency
-
Macdonald ST, Bamforth SD, Chen CM, Farthing CR, Franklyn A, Broadbent C, Schneider JE, Saga Y, Lewandoski M, Bhattacharya S (2008) Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency. Cardiovasc Res.
-
(2008)
Cardiovasc Res
-
-
Macdonald, S.T.1
Bamforth, S.D.2
Chen, C.M.3
Farthing, C.R.4
Franklyn, A.5
Broadbent, C.6
Schneider, J.E.7
Saga, Y.8
Lewandoski, M.9
Bhattacharya, S.10
-
29
-
-
0038784537
-
Two populations of node monocilia initiate left-right asymmetry in the mouse
-
McGrath J, Somlo S, Makova S, Tian X, Brueckner M (2003) Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell 114:61-73.
-
(2003)
Cell
, vol.114
, pp. 61-73
-
-
McGrath, J.1
Somlo, S.2
Makova, S.3
Tian, X.4
Brueckner, M.5
-
30
-
-
0032493876
-
Lefty-1 is required for leftright determination as a regulator of lefty-2 and Nodal
-
Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, Ohishi S, Noji S, Kondoh H, Hamada H (1998) lefty-1 is required for leftright determination as a regulator of lefty-2 and Nodal. Cell 94:287-297.
-
(1998)
Cell
, vol.94
, pp. 287-297
-
-
Meno, C.1
Shimono, A.2
Saijoh, Y.3
Yashiro, K.4
Mochida, K.5
Ohishi, S.6
Noji, S.7
Kondoh, H.8
Hamada, H.9
-
31
-
-
18044400212
-
Diffusion of Nodal signaling activity in the absence of the feedback inhibitor Lefty2
-
Meno C, Takeuchi J, Sakuma R, Koshiba-Takeuchi K, Ohishi S, Saijoh Y, Miyazaki J, ten Dijke P, Ogura T, Hamada H (2001) Diffusion of Nodal signaling activity in the absence of the feedback inhibitor Lefty2. Dev Cell 1:127-138.
-
(2001)
Dev Cell
, vol.1
, pp. 127-138
-
-
Meno, C.1
Takeuchi, J.2
Sakuma, R.3
Koshiba-Takeuchi, K.4
Ohishi, S.5
Saijoh, Y.6
Miyazaki, J.7
Ten, D.P.8
Ogura, T.9
Hamada, H.10
-
32
-
-
0033575364
-
Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH
-
Meyers EN, Martin GR (1999) Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. Science 285:403-406.
-
(1999)
Science
, vol.285
, pp. 403-406
-
-
Meyers, E.N.1
Martin, G.R.2
-
33
-
-
50249186349
-
BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment
-
Mine N, Anderson RM, Klingensmith J (2008) BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. Development 135:2425-2434.
-
(2008)
Development
, vol.135
, pp. 2425-2434
-
-
Mine, N.1
Anderson, R.M.2
Klingensmith, J.3
-
34
-
-
31144437395
-
Wnt3alinks left-right determination with segmentation and anteroposterior axis elongation
-
Nakaya MA, Biris K, Tsukiyama T, Jaime S, Rawls JA, Yamaguchi TP (2005) Wnt3alinks left-right determination with segmentation and anteroposterior axis elongation. Development 132:5425-5436.
-
(2005)
Development
, vol.132
, pp. 5425-5436
-
-
Nakaya, M.A.1
Biris, K.2
Tsukiyama, T.3
Jaime, S.4
Rawls, J.A.5
Yamaguchi, T.P.6
-
35
-
-
63949088362
-
FGF signalling during embryo development regulates cilia length in diverse epithelia
-
Neugebauer JM, Amack JD, Peterson AG, Bisgrove BW, Yost HJ (2009) FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature 458:651-654.
-
(2009)
Nature
, vol.458
, pp. 651-654
-
-
Neugebauer, J.M.1
Amack, J.D.2
Peterson, A.G.3
Bisgrove, B.W.4
Yost, H.J.5
-
36
-
-
0037019287
-
Determination of left-right patterning of the mouse embryo by artificial Nodal flow
-
Nonaka S, Shiratori H, Saijoh Y, Hamada H (2002) Determination of left-right patterning of the mouse embryo by artificial Nodal flow. Nature 418:96-99.
-
(2002)
Nature
, vol.418
, pp. 96-99
-
-
Nonaka, S.1
Shiratori, H.2
Saijoh, Y.3
Hamada, H.4
-
37
-
-
0036638778
-
The FoxH1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo.
-
Norris DP, Brennan J, Bikoff EK, Robertson EJ (2002) The FoxH1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development 129:3455-3468.
-
(2002)
Development
, vol.129
, pp. 3455-3468
-
-
Norris, D.P.1
Brennan, J.2
Bikoff, E.K.3
Robertson, E.J.4
-
38
-
-
33646706385
-
Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field
-
Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE (2006) Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development 133:1565-1573.
-
(2006)
Development
, vol.133
, pp. 1565-1573
-
-
Nowotschin, S.1
Liao, J.2
Gage, P.J.3
Epstein, J.A.4
Campione, M.5
Morrow, B.E.6
-
39
-
-
0033212985
-
Abnormal Nodal flow precedes situs inversus in iv and inv mice
-
Okada Y, Nonaka S, Tanaka Y, Saijoh Y, Hamada H, Hirokawa N (1999) Abnormal Nodal flow precedes situs inversus in iv and inv mice. Mol Cell 4:459-468.
-
(1999)
Mol Cell
, vol.4
, pp. 459-468
-
-
Okada, Y.1
Nonaka, S.2
Tanaka, Y.3
Saijoh, Y.4
Hamada, H.5
Hirokawa, N.6
-
40
-
-
36549035731
-
Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo
-
Oki S, Hashimoto R, Okui Y, Shen MM, Mekada E, Otani H, Saijoh Y, Hamada H (2007) Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo. Development 134:3893-3904.
-
(2007)
Development
, vol.134
, pp. 3893-3904
-
-
Oki, S.1
Hashimoto, R.2
Okui, Y.3
Shen, M.M.4
Mekada, E.5
Otani, H.6
Saijoh, Y.7
Hamada, H.8
-
41
-
-
0036479029
-
Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry
-
Olbrich H, Haffner K, Kispert A, Volkel A, Volz A, Sasmaz G, Reinhardt R, Hennig S, Lehrach H, Konietzko N, Zariwala M, Noone PG, Knowles M, Mitchison HM, Meeks M, Chung EM, Hildebrandt F, Sudbrak R, Omran H (2002) Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nat Genet 30:143-144.
-
(2002)
Nat Genet
, vol.30
, pp. 143-144
-
-
Olbrich, H.1
Haffner, K.2
Kispert, A.3
Volkel, A.4
Volz, A.5
Sasmaz, G.6
Reinhardt, R.7
Hennig, S.8
Lehrach, H.9
Konietzko, N.10
Zariwala, M.11
Noone, P.G.12
Knowles, M.13
Mitchison, H.M.14
Meeks, M.15
Chung, E.M.16
Hildebrandt, F.17
Sudbrak, R.18
Omran, H.19
-
42
-
-
0037232490
-
Node and midline defects are associated with left-right development in Delta1 mutant embryos
-
Przemeck GK, Heinzmann U, Beckers J, Hrabe de Angelis M (2003) Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development 130:3-13.
-
(2003)
Development
, vol.130
, pp. 3-13
-
-
Przemeck, G.K.1
Heinzmann, U.2
Beckers, J.3
Hrabe De Angelis, M.4
-
43
-
-
28244501046
-
Left-right asymmetry and congenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination
-
Ramsdell AF (2005) Left-right asymmetry and congenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination. Dev Biol 288:1-20.
-
(2005)
Dev Biol
, vol.288
, pp. 1-20
-
-
Ramsdell, A.F.1
-
44
-
-
8444251340
-
Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates
-
Rana AA, Barbera JP, Rodriguez TA, Lynch D, Hirst E, Smith JC, Beddington RS (2004) Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates. Development 131:4999-5007.
-
(2004)
Development
, vol.131
, pp. 4999-5007
-
-
Rana, A.A.1
Barbera, J.P.2
Rodriguez, T.A.3
Lynch, D.4
Hirst, E.5
Smith, J.C.6
Beddington, R.S.7
-
45
-
-
0028354113
-
Alterations in gene expression during mesoderm formation and axial patterning in Brachyury (T) embryos
-
Rashbass P, Wilson V, Rosen B, Beddington RS (1994) Alterations in gene expression during mesoderm formation and axial patterning in Brachyury (T) embryos. Int J Dev Biol 38:35-44.
-
(1994)
Int J Dev Biol
, vol.38
, pp. 35-44
-
-
Rashbass, P.1
Wilson, V.2
Rosen, B.3
Beddington, R.S.4
-
46
-
-
0037598796
-
Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos
-
Raya A, Kawakami Y, Rodriguez-Esteban C, Buscher D, Koth CM, Itoh T, Morita M, Raya RM, Dubova I, Bessa JG, de la Pompa JL, Belmonte JC (2003) Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. Genes Dev 17:1213-1218.
-
(2003)
Genes Dev
, vol.17
, pp. 1213-1218
-
-
Raya, A.1
Kawakami, Y.2
Rodriguez-Esteban, C.3
Buscher, D.4
Koth, C.M.5
Itoh, T.6
Morita, M.7
Raya, R.M.8
Dubova, I.9
Bessa, J.G.10
De La Pompa, J.L.11
Belmonte, J.C.12
-
47
-
-
0347192982
-
Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination
-
Raya A, Kawakami Y, Rodriguez-Esteban C, Ibanes M, Rasskin-Gutman D, Rodriguez-Leon J, Buscher D, Feijo JA, Izpisua Belmonte JC (2004) Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination. Nature 427:121-128.
-
(2004)
Nature
, vol.427
, pp. 121-128
-
-
Raya, A.1
Kawakami, Y.2
Rodriguez-Esteban, C.3
Ibanes, M.4
Rasskin-Gutman, D.5
Rodriguez-Leon, J.6
Buscher, D.7
Feijo, J.A.8
Izpisua Belmonte, J.C.9
-
48
-
-
65449133141
-
Signaling pathways controlling second heart field development
-
Rochais F, Mesbah K, Kelly RG (2009) Signaling pathways controlling second heart field development. Circ Res 104: 933-942.
-
(2009)
Circ Res
, vol.104
, pp. 933-942
-
-
Rochais, F.1
Mesbah, K.2
Kelly, R.G.3
-
49
-
-
46149123644
-
Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly
-
Roessler E, Ouspenskaia MV, Karkera JD, Velez JI, Kantipong A, Lacbawan F, Bowers P, Belmont JW, Towbin JA, Goldmuntz E, Feldman B, Muenke M (2008) Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly. Am J Hum Genet 83:18-29.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 18-29
-
-
Roessler, E.1
Ouspenskaia, M.V.2
Karkera, J.D.3
Velez, J.I.4
Kantipong, A.5
Lacbawan, F.6
Bowers, P.7
Belmont, J.W.8
Towbin, J.A.9
Goldmuntz, E.10
Feldman, B.11
Muenke, M.12
-
50
-
-
70349324257
-
The motile cilium in development and disease: emerging new insights
-
Roy S (2009) The motile cilium in development and disease: emerging new insights. Bioessays 31:694-699.
-
(2009)
Bioessays
, vol.31
, pp. 694-699
-
-
Roy, S.1
-
51
-
-
0033969935
-
Left-right asymmetric expression of Lefty2 and Nodal is induced by a signaling pathway that includes the transcription factor FAST2
-
Saijoh Y, Adachi H, Sakuma R, Yeo CY, Yashiro K, Watanabe M, Hashiguchi H, Mochida K, Ohishi S, Kawabata M, Miyazono K, Whitman M, Hamada H (2000) Left-right asymmetric expression of Lefty2 and Nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell 5:35-47.
-
(2000)
Mol Cell
, vol.5
, pp. 35-47
-
-
Saijoh, Y.1
Adachi, H.2
Sakuma, R.3
Yeo, C.Y.4
Yashiro, K.5
Watanabe, M.6
Hashiguchi, H.7
Mochida, K.8
Ohishi, S.9
Kawabata, M.10
Miyazono, K.11
Whitman, M.12
Hamada, H.13
-
52
-
-
0345255908
-
Nodal signaling in vertebrate development
-
Schier AF (2003) Nodal signaling in vertebrate development. Annu Rev Cell Dev Biol 19:589-621.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 589-621
-
-
Schier, A.F.1
-
53
-
-
77954759754
-
Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 Mutations
-
Schwabe GC, Hoffmann K, Loges NT, Birker D, Rossier C, de Santi MM, Olbrich H, Fliegauf M, Failly M, Liebers U, Collura M, Gaedicke G, Mundlos S, Wahn U, Blouin JL, Niggemann B, Omran H, Antonarakis SE, Bartoloni L (2007) Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 Mutations. Hum Mutat.
-
(2007)
Hum Mutat
-
-
Schwabe, G.C.1
Hoffmann, K.2
Loges, N.T.3
Birker, D.4
Rossier, C.5
De Santi, M.M.6
Olbrich, H.7
Fliegauf, M.8
Failly, M.9
Liebers, U.10
Collura, M.11
Gaedicke, G.12
Mundlos, S.13
Wahn, U.14
Blouin, J.L.15
Niggemann, B.16
Omran, H.17
Antonarakis, S.E.18
Bartoloni, L.19
-
54
-
-
0028905544
-
Requirement for Lim1 in headorganizer function
-
Shawlot W, Behringer RR (1995) Requirement for Lim1 in headorganizer function. Nature 374:425-430.
-
(1995)
Nature
, vol.374
, pp. 425-430
-
-
Shawlot, W.1
Behringer, R.R.2
-
55
-
-
33745612029
-
The left-right axis in the mouse: from origin to morphology
-
Shiratori H, Hamada H (2006) The left-right axis in the mouse: from origin to morphology. Development 133:2095-2104.
-
(2006)
Development
, vol.133
, pp. 2095-2104
-
-
Shiratori, H.1
Hamada, H.2
-
56
-
-
17744364498
-
Two-step regulation of left-right asymmetric expression of Pitx2: initiation by Nodal signaling and maintenance by Nkx2
-
Shiratori H, Sakuma R, Watanabe M, Hashiguchi H, Mochida K, Sakai Y, Nishino J, Saijoh Y, Whitman M, Hamada H (2001) Two-step regulation of left-right asymmetric expression of Pitx2: initiation by Nodal signaling and maintenance by Nkx2. Mol Cell 7:137-149.
-
(2001)
Mol Cell
, vol.7
, pp. 137-149
-
-
Shiratori, H.1
Sakuma, R.2
Watanabe, M.3
Hashiguchi, H.4
Mochida, K.5
Sakai, Y.6
Nishino, J.7
Saijoh, Y.8
Whitman, M.9
Hamada, H.10
-
57
-
-
51549114034
-
Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis
-
Slough J, Cooney L, Brueckner M (2008) Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis. Dev Dyn 237:2304-2314.
-
(2008)
Dev Dyn
, vol.237
, pp. 2304-2314
-
-
Slough, J.1
Cooney, L.2
Brueckner, M.3
-
58
-
-
0030656618
-
Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
-
Supp DM, Witte DP, Potter SS, Brueckner M (1997) Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389:963-966.
-
(1997)
Nature
, vol.389
, pp. 963-966
-
-
Supp, D.M.1
Witte, D.P.2
Potter, S.S.3
Brueckner, M.4
-
59
-
-
0037229694
-
A two-cilia model for vertebrate leftright axis specification
-
Tabin CJ, Vogan KJ (2003) A two-cilia model for vertebrate leftright axis specification. Genes Dev 17:1-6.
-
(2003)
Genes Dev
, vol.17
, pp. 1-6
-
-
Tabin, C.J.1
Vogan, K.J.2
-
60
-
-
33846465548
-
Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry
-
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG (2007) Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proc Natl Acad Sci USA 104:846-851.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 846-851
-
-
Takeuchi, J.K.1
Lickert, H.2
Bisgrove, B.W.3
Sun, X.4
Yamamoto, M.5
Chawengsaksophak, K.6
Hamada, H.7
Yost, H.J.8
Rossant, J.9
Bruneau, B.G.10
-
61
-
-
18744406718
-
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward Nodal flow is critical for left-right determination
-
Tanaka Y, Okada Y, Hirokawa N (2005) FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward Nodal flow is critical for left-right determination. Nature 435:172-177.
-
(2005)
Nature
, vol.435
, pp. 172-177
-
-
Tanaka, Y.1
Okada, Y.2
Hirokawa, N.3
-
62
-
-
37249093137
-
Long-range action of Nodal requires interaction with GDF1
-
Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y (2007) Long-range action of Nodal requires interaction with GDF1. Genes Dev 21:3272-3282.
-
(2007)
Genes Dev
, vol.21
, pp. 3272-3282
-
-
Tanaka, C.1
Sakuma, R.2
Nakamura, T.3
Hamada, H.4
Saijoh, Y.5
-
63
-
-
42049098616
-
Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs
-
Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M (2008) Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circ Res 102:813-822.
-
(2008)
Circ Res
, vol.102
, pp. 813-822
-
-
Tessari, A.1
Pietrobon, M.2
Notte, A.3
Cifelli, G.4
Gage, P.J.5
Schneider, M.D.6
Lembo, G.7
Campione, M.8
-
64
-
-
0033613180
-
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the Shh and retinoic acid pathways in the control of Lefty-1
-
Tsukui T, Capdevila J, Tamura K, Ruiz-Lozano P, Rodriguez- Esteban C, Yonei-Tamura S, Magallon J, Chandraratna RA, Chien K, Blumberg B, Evans RM, Belmonte JC (1999) Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the Shh and retinoic acid pathways in the control of Lefty-1. Proc Natl Acad Sci USA 96:11376-11381.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11376-11381
-
-
Tsukui, T.1
Capdevila, J.2
Tamura, K.3
Ruiz-Lozano, P.4
Rodriguez-, E.C.5
Yonei-Tamura, S.6
Magallon, J.7
Chandraratna, R.A.8
Chien, K.9
Blumberg, B.10
Evans, R.M.11
Belmonte, J.C.12
-
65
-
-
34047098378
-
Role of bone morphogenetic proteins in cardiac differentiation
-
van Wijk B, Moorman AF, van den Hoff MJ (2007) Role of bone morphogenetic proteins in cardiac differentiation. Cardiovasc Res 74:244-255.
-
(2007)
Cardiovasc Res
, vol.74
, pp. 244-255
-
-
Van Wijk, B.1
Moorman, A.F.2
Van Den Hoff, M.J.3
-
66
-
-
51949085076
-
Hedgehog: functions and mechanisms
-
Varjosalo M, Taipale J (2008) Hedgehog: functions and mechanisms. Genes Dev 22:2454-2472.
-
(2008)
Genes Dev
, vol.22
, pp. 2454-2472
-
-
Varjosalo, M.1
Taipale, J.2
-
67
-
-
0347003520
-
Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects
-
Ware SM, Peng J, Zhu L, Fernbach S, Colicos S, Casey B, Towbin J, Belmont JW (2004) Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects. Am J Hum Genet 74:93-105.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 93-105
-
-
Ware, S.M.1
Peng, J.2
Zhu, L.3
Fernbach, S.4
Colicos, S.5
Casey, B.6
Towbin, J.7
Belmont, J.W.8
-
68
-
-
0036338736
-
Phenotyping transgenic embryos: a rapid 3-D screening method based on episcopic fluorescence image capturing
-
Weninger WJ, Mohun T (2002) Phenotyping transgenic embryos: a rapid 3-D screening method based on episcopic fluorescence image capturing. Nat Genet 30:59-65.
-
(2002)
Nat Genet
, vol.30
, pp. 59-65
-
-
Weninger, W.J.1
Mohun, T.2
-
69
-
-
17244379390
-
Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development
-
Weninger WJ, Floro KL, Bennett MB, Withington SL, Preis JI, Barbera JP, Mohun TJ, Dunwoodie SL (2005) Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development. Development 132:1337-1348.
-
(2005)
Development
, vol.132
, pp. 1337-1348
-
-
Weninger, W.J.1
Floro, K.L.2
Bennett, M.B.3
Withington, S.L.4
Preis, J.I.5
Barbera, J.P.6
Mohun, T.J.7
Dunwoodie, S.L.8
-
70
-
-
0035872927
-
The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse
-
Yamamoto M, Meno C, Sakai Y, Shiratori H, Mochida K, Ikawa Y, Saijoh Y, Hamada H (2001) The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev 15:1242-1256.
-
(2001)
Genes Dev
, vol.15
, pp. 1242-1256
-
-
Yamamoto, M.1
Meno, C.2
Sakai, Y.3
Shiratori, H.4
Mochida, K.5
Ikawa, Y.6
Saijoh, Y.7
Hamada, H.8
-
71
-
-
0012547516
-
Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate
-
Yamamoto M, Mine N, Mochida K, Sakai Y, Saijoh Y, Meno C, Hamada H (2003) Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate. Development 130:1795-1804.
-
(2003)
Development
, vol.130
, pp. 1795-1804
-
-
Yamamoto, M.1
Mine, N.2
Mochida, K.3
Sakai, Y.4
Saijoh, Y.5
Meno, C.6
Hamada, H.7
-
72
-
-
36448961540
-
Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms
-
Yamanaka Y, Tamplin OJ, Beckers A, Gossler A, Rossant J (2007) Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell 13:884-896.
-
(2007)
Dev Cell
, vol.13
, pp. 884-896
-
-
Yamanaka, Y.1
Tamplin, O.J.2
Beckers, A.3
Gossler, A.4
Rossant, J.5
-
73
-
-
0033215180
-
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
-
Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM (1999) Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev 13:2527-2537.
-
(1999)
Genes Dev
, vol.13
, pp. 2527-2537
-
-
Yan, Y.T.1
Gritsman, K.2
Ding, J.3
Burdine, R.D.4
Corrales, J.D.5
Price, S.M.6
Talbot, W.S.7
Schier, A.F.8
Shen, M.M.9
-
74
-
-
36048995640
-
Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
-
Yashiro K, Shiratori H, Hamada H (2007) Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch. Nature 450:285-288.
-
(2007)
Nature
, vol.450
, pp. 285-288
-
-
Yashiro, K.1
Shiratori, H.2
Hamada, H.3
-
75
-
-
0036679122
-
The essential role of Cited2, a negative regulator for HIF-1{alpha}, in heart development and neurulation
-
Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Prabhakar NR, Herrup K, Conlon RA, Hoit BD, Watanabe M, Yang YC (2002) The essential role of Cited2, a negative regulator for HIF-1{alpha}, in heart development and neurulation. Proc Natl Acad Sci USA 99:10488-10493.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10488-10493
-
-
Yin, Z.1
Haynie, J.2
Yang, X.3
Han, B.4
Kiatchoosakun, S.5
Restivo, J.6
Yuan, S.7
Prabhakar, N.R.8
Herrup, K.9
Conlon, R.A.10
Hoit, B.D.11
Watanabe, M.12
Yang, Y.C.13
-
76
-
-
0035958941
-
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node
-
Zhang XM, Ramalho-Santos M, McMahon AP (2001) Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell 106:781-792.
-
(2001)
Cell
, vol.106
, pp. 781-792
-
-
Zhang, X.M.1
Ramalho-Santos, M.2
McMahon, A.P.3
|