Social interaction prevents the development of depressive-like behavior post nerve injury in mice: A potential role for oxytocin

Psychosomatic Medicine

Volumn 72, Issue 6, 2010, Pages 519-526

  Norman, Greg J ^a,c   Karelina, Kate ^b   Morris, John S ^a   Zhang, Ning ^b   Cochran, Megan ^b   Devries, A Courtney ^a,b,c  

^a Departments of Psychology   (United States)

^b Institute for Behavioral Medicine Research   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Depression; Interleukin .; Neuropathic; Oxytocin; Social

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; NEUROPEPTIDE; OXYTOCIN; PROTEIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; FORCED SWIMMING TEST; FRONTAL CORTEX; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; SOCIAL INTERACTION; SOCIAL ISOLATION;

ANIMALS; BEHAVIOR, ANIMAL; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; OXYTOCIN; PAIN THRESHOLD; PERIPHERAL NERVES; PHYSICAL EXERTION; PREFRONTAL CORTEX; RECEPTORS, OXYTOCIN; SOCIAL BEHAVIOR; SOCIAL ENVIRONMENT; SOCIAL ISOLATION; SWIMMING;

EID: 77954759328     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0b013e3181de8678     Document Type: Article

References (42)

1. Gatchel RJ, Turk DC (Editors), Psychological Approaches to Pain Management: A Practitioner's Handbook
2. Wise TN, Fishbain DA, Holder-Perkins V. Painful physical symptoms in depression: a clinical challenge. Pain Med 2007;2(8 Suppl):S75-82.
3. Neugebauer V, Li W, Bird GC, Han JS. The amygdala and persistent pain. Neuroscientist 2004;10:221-34.
4. Xu H, Wu LJ, Wang H, Zhang X, Vadakkan KI, Kim SS, Steenland HW, Zhuo M. Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex. J Neurosci 2008;28:7445-53.
5. Apkarian AV, Lavarello S, Randolf A, Berra HH, Chialvo DR, Bese-dovsky HO, del Rey A. Expression of IL-1beta in supraspinal brain regions in rats with neuropathic pain. Neurosci Lett 2006;407:176-81.
6. Goncalves L, Silva R, Pinto-Ribeiro F, Pego JM, Bessa JM, Pertovaara A, Sousa N, Almeida A. Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat. Exp Neurol 2008;213:48-56.
7. Metz AE, Yau HJ, Centeno MV, Apkarian AV, Martina M. Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain. Proc Natl Acad Sci USA 2009;106:2423-8.
8. Dworkin RH, Gitlin MJ. Clinical aspects of depression in chronic pain patients. Clin J Pain 1991;7:79-94.
9. Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008;9:46-56.
10. Norman GJ, Karelina K, Zhang N, Walton JC, Morris JS, Devries AC. Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury. Mol Psychiatry 2010;15: 404-14.
11. Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 2006;27:24-31.
12. Detillion CE, Craft TK, Glasper ER, Prendergast BJ, DeVries AC. Social facilitation of wound healing. Psychoneuroendocrinology 2004;29: 1004-11.
13. DeVries AC, Craft TK, Glasper ER, Neigh GN, Alexander JK. 2006 Curt P. Richter award winner: social influences on stress responses and health. Psychoneuroendocrinology 2007;32:587-603.
14. Turner RA, Altemus M, Enos T, Cooper B, McGuinness T. Preliminary research on plasma oxytocin in normal cycling women: investigating emotion and interpersonal distress. Psychiatry 1999;62:97-113.
15. Grewen KM, Girdler SS, Amico J, Light KC. Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosom Med 2005;67:531-8.
16. Ferguson JN, Aldag JM, Insel TR, Young LJ. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J Neurosci 2001;21:8278-85.
17. Young LJ. The neurobiology of social recognition, approach, and avoidance. Biol Psychiatry 2002;51:18-26.
18. Grippo AJ, Wu KD, Hassan I, Carter CS. Social isolation in prairie voles induces behaviors relevant to negative affect: toward the development of a rodent model focused on co-occurring depression and anxiety. Depress Anxiety 2008;25:E17-26.
19. Miranda-Cardenas Y, Rojas-Piloni G, Martinez-Lorenzana G, Rodriguez-Jimenez J, Lopez-Hidalgo M, Freund-Mercier MJ, Condes-Lara M. Oxy-tocin and electrical stimulation of the paraventricular hypothalamic nucleus produce antinociceptive effects that are reversed by an oxytocin antagonist. Pain 2006;122:182-9.
20. Arletti R, Bertolini A. Oxytocin acts as an antidepressant in two animal models of depression. Life Sci 1987;41:1725-30.
21. Slattery DA, Neumann ID. Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats. Neuropharmacol-ogy 2009;58:56-61.
22. Bourquin AF, Süveges M, Pertin M, Gilliard N, Sardy S, Davison AC, Spahn DR, Decosterd I. Assessment and analysis of mechanical allo-dynia-like behavior induced by spared nerve injury (SNI) in the mouse. Pain 2006;122:14.e1-14.
23. Porsolt RD, Brossard G, Hautbois C, Roux S. Rodent models of depression: forced swimming and tail suspension behavioral despair tests in rats and mice. Curr Protoc Neurosci 2001;Chapter 8:Unit 8.10A.
24. Vanegas H, Schaible HG. Descending control of persistent pain: inhibitory or facilitatory? Brain Res Brain Res Rev 2004;46:295-309.
25. Levine J, Barak Y, Chengappa KN, Rapoport A, Rebey M, Barak V. Cerebrospinal cytokine levels in patients with acute depression. Neuro-psychobiology 1999;40:171-6.
26. Anisman H, Ravindran AV, Griffiths J, Merali Z. Endocrine and cytokine correlates of major depression and dysthymia with typical or atypical features. Mol Psychiatry 1999;4:182-8.
27. Thomas AJ, Davis S, Morris C, Jackson E, Harrison R, O'Brien JT. Increase in interleukin-1beta in late-life depression. Am J Psychiatry 2005;162:175-7.
28. Strouse TB. The relationship between cytokines and pain/depression: a review and current status. Curr Pain Headache Rep 2007;11:98-103.
29. Yu YW, Chen TJ, Hong CJ, Chen HM, Tsai SJ. Association study of the interleukin-1 beta (C-511T) genetic polymorphism with major depressive disorder, associated symptomatology, and antidepressant response. Neu- ropsychopharmacology 2003;28:1182-5.
30. Clodi M, Vila G, Geyeregger R, Riedl M, Stulnig TM, Struck J, Luger TA, Luger A. Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men. Am J Physiol Endocrinol Metab 2008;295:E686-91.
31. Petersson M, Wiberg U, Lundeberg T, Uvnas-Moberg K. Oxytocin decreases carrageenan induced inflammation in rats. Peptides 2001;22: 1479-84.
32. Condes-Lara M, Rojas-Piloni G, Martinez-Lorenzana G, Lopez-Hidalgo M, Rodriguez-Jimenez J. Hypothalamospinal oxytocinergic antinocicep-tion is mediated by GABAergic and opiate neurons that reduce A-delta and C fiber primary afferent excitation of spinal cord cells. Brain Res 2009;1247:38-49.
33. Craig AD. A new view of pain as a homeostatic emotion. Trends Neurosci 2003;26:303-7.
34. Schorscher-Petchu A, Sotocinal S, Crawley JN, Young LJ, Quirion R, Mogil JS. Oxytocin-induced analgesia is not mediated by the oxytocin receptor, but rather by the vasopressin-1A receptor: Evidence from oxy-tocin-and vasopressin-receptor knockout mice. Program No. 170.19. Poster No. X21. Chicago, IL: Society for Neuroscience, 2009. http://www.abstractsonline.com/Plan/start. aspx. Accessed April 8, 2010.
35. Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U. Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 2003;54:1389-98.
36. Manning M, Stoev S, Chini B, Durroux T, Mouillac B, Guillon G. Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents. Prog Brain Res 2008;170:473-512.
37. Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E. Oxytocin increases trust in humans. Nature 2005;435:673-6.
38. Guastella AJ, Carson DS, Dadds MR, Mitchell PB, Cox RE. Does oxytocin influence the early detection of angry and happy faces? Psy- choneuroendocrinology 2009;34:220-5.
39. Ditzen B, Schaer M, Gabriel B, Bodenmann G, Ehlert U, Heinrichs M. Intranasal oxytocin increases positive communication and reduces corti-sol levels during couple conflict. Biol Psychiatry 2009;65:728-31.
40. Lucht MJ, Barnow S, Sonnenfeld C, Rosenberger A, Grabe HJ, Schroe-der W, Volzke H, Freyberger HJ, Herrmann FH, Kroemer H, Rosskopf D. Associations between the oxytocin receptor gene (OXTR) and affect, loneliness and intelligence in normal subjects. Prog Neuropsychophar-macol Biol Psychiatry 2009;33:860-6.
41. Costa B, Pini S, Gabelloni P, Abelli M, Lari L, Cardini A, Muti M, Gesi C, Landi S, Galderisi S, Mucci A, Lucacchini A, Cassano GB, Martini C. Oxytocin receptor polymorphisms and adult attachment style in patients with depression. Psychoneuroendocrinology 2009;34:1506-14.
42. Rodrigues SM, Saslow LR, Garcia N, John OP, Keltner D. Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. Proc Natl Acad Sci USA 2009;106:21437-41.