Oxytocin receptor polymorphisms and adult attachment style in patients with depression

Psychoneuroendocrinology

Volumn 34, Issue 10, 2009, Pages 1506-1514

  Costa, Barbara ^a   Pini, Stefano ^a   Gabelloni, Pamela ^a   Abelli, Marianna ^a   Lari, Lisa ^a   Cardini, Alessandra ^a   Muti, Matteo ^a   Gesi, Camilla ^a   Landi, Stefano ^a   Galderisi, Silvana ^b   Mucci, Armida ^b   Lucacchini, Antonio ^a   Cassano, Giovanni B ^a   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Adult attachment style; Bipolar depression; Haplotype; Oxytocin; Oxytocin receptor; Single nucleotide polymorphisms; Unipolar depression

Indexed keywords

OXYTOCIN RECEPTOR;

ADULT; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; COHORT ANALYSIS; CONTROLLED STUDY; EMOTIONAL ATTACHMENT; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PRIORITY JOURNAL; PSYCHOMETRY; QUESTIONNAIRE; RNA SPLICING; SCORING SYSTEM; SEPARATION ANXIETY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANXIETY, SEPARATION; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MOOD DISORDERS; OBJECT ATTACHMENT; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, OXYTOCIN; RNA SPLICING;

EID: 70349798585     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2009.05.006     Document Type: Article

References (48)

1. aan het Rot M., Mathew S.J., and Charney D.S. Neurobiological mechanisms in major depressive disorder. CMAJ 180 (2009) 305-313
2. Bartholomew K., and Horowitz L.M. Attachment style among young adults: a test of a four-category model. J. Pers. Soc. Psychol. 61 (1991) 226-244
3. Bell C.J., Nicholson H., Mulder R.T., Luty S.E., and Joyce P.R. Plasma oxytocin levels in depression and their correlation with the temperament dimension of reward dependence. J. Psychopharmacol. 20 5 (2006) 656-660
4. Bifulco A., Moran P.M., Ball C., and Bernazzani O. Adult attachment style. I. Its relationship to clinical depression. Soc. Psychiatry Psychiatr. Epidemiol. 37 (2002) 50-59
5. Bottonari K.A., Roberts J.E., Kelly M.A., Kashdan T.B., and Ciesla J.A. A prospective investigation of the impact of attachment style on stress generation among clinically depressed individuals. Behav. Res. Ther. 45 1 (2007) 179-188
6. Brennan K.A., Clark C.L., and Shaver P.R. Self-report measurement of adult attachment: an integrative overview. In: Simpson J.A., and Rholes W.S. (Eds). Attachment Theory and Close Relationships (1998), Guilford Press, New York 46-76
7. Carlson E.A. A prospective longitudinal study of attachment disorganization/disorientation. Child Dev. 69 (1998) 1107-1128
8. Carnelley K.B., Pietromonacó P.R., and Jaffe K. Depression, working models of others, and relationship functioning. J. Pers. Soc. Psychol. 66 (1994) 127-140
9. Carter C.S. Neuroendocrine perspectives on social attachment and love. Psychoneuroendocrinology 23 (1998) 779-818
10. Collins N.L. Working models of attachment: implications for explanation, emotion and behavior. J. Pers. Soc. Psychol. 71 (1996) 810-832
11. Conradi H.J., and de Jonge P. Recurrent depression and the role of adult attachment: a prospective and a retrospective study. J. Affect. Disord. (2008) 10.1016/j.jad.2008.10.027
12. Cubells J.F., Kobayashi K., Nagatsu T., Kidd K.K., Kidd J.R., Calafell F., et al. Population genetics of a functional variant of the dopamine beta-hydroxylase gene (DBH). Am. J. Med. Genet. 74 (1997) 374-379
13. Cyranowski J.M., Hofkens T.L., Frank E., Seltman H., Cai H.M., and Amico J.A. Evidence of dysregulated peripheral oxytocin release among depressed women. Psychosom. Med. 70 (2008) 967-975
14. Donaldson Z.R., and Young L.J. Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322 (2008) 900-904
15. Donnellan M.B., Burt S.A., Levendosky A.A., and Klump K.L. Genes, personality, and attachment in adults: a multivariate behavioral genetic analysis. Pers. Soc. Psychol. Bull. 34 (2008) 3-16
16. Feeney J.A., Noller P., and Hanrahan M. Assessing adult attachment. In: Sperling M.B., and Berman W.H. (Eds). Attachment in Adults: Clinical and Developmental Perspectives (1994), Guilford Press, New York 128-152
17. First M.B., Spitzer R.L., Gibbon M., and Williams J.B.W. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I/P) (2002), Biometrics Research, New York State Psychiatric Institute, New York
18. Fossati A., Feeney J.A., Donati D., Donini M., Novella L., Bagnato M., Acquarini E., and Maffei C. On the dimensionality of the Attachment Style Questionnaire in Italian clinical and nonclinical participants. J. Soc. Pers. Relat. 20 (2003) 55-79
19. Fraley R.C., Fazzari D.A., Bonanno G.A., and Dekel S. Attachment and psychological adaptation in high exposure survivors of the September 11th attack on the World Trade Center. Pers. Soc. Psychol. Bull. 32 4 (2006) 538-551
20. Gillath O., Shaver P.R., Baek J.M., and Chun D.S. Genetic correlates of adult attachment style. Pers. Soc. Psychol. Bull. 34 (2008) 1396-1405
21. Griffin D.W., and Bartholomew K. Models of the self and other: fundamental dimensions underlying measures of adult attachment. J. Pers. Soc. Psychol. 67 (1994) 430-445
22. Grippo A.J., Gerena D., Huang J., Kumar N., Shah M., Ughreja R., and Carter C.S. Social isolation induces behavioral and neuroendocrine disturbances relevant to depression in female and male prairie voles. Psychoneuroendocrinology 32 (2007) 966-980
23. Hamet P., and Tremblay J. Genetics and genomics of depression. Metabolism 54 (2005) 10-15
24. Hamilton M. The assessment of anxiety states by rating. Br. J. Med. Psychol. 32 (1959) 50-55
25. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 23 (1960) 56-62
26. Hazan C., and Shaver P. Romantic love conceptualized as an attachment process. J. Pers. Soc. Psychol. 52 (1987) 511-524
27. Insel T.R. A neurobiological basis of social attachment. Am. J. Psychiatry 154 (1997) 726-734
28. Insel T.R. Oxytocin-a neuropeptide for affiliation: evidence from behavioral, receptor autoradiographic, and comparative studies. Psychoneuroendocrinology 17 (1992) 3-35
29. Main M. Introduction to the special section on attachment and psychopathology. 2. Overview of the field of attachment. J. Consult. Clin. Psychol. 64 (1996) 237-243
30. Manicavasagar V., Silove D., Wagner R., and Drobny J. A selfreport questionnaire for measuring separation anxiety in adulthood. Comp. Psychiatry 44 (2003) 146-153
31. Martinowich K., Schloesser R.J., and Manji H.K. Bipolar disorder: from genes to behavior pathways. J. Clin. Invest. 119 (2009) 726-736
32. Mickelson K.D., Kessler R.C., and Shaver P.R. Adult attachment in a nationally representative sample. J. Pers. Soc. Psychol. 73 (1997) 1092-1106
33. Mikulincer M., and Shaver P.R. Attachment in Adulthood: Structure Dynamics, and Change. Activation, Psychodynamics, and Interpersonal Processes (2007), Guilford Press, New York
34. Murphy B., and Bates G.W. Adult attachment style and vulnerability to depression. Person. Individ. Diff. 22 (1997) 835-844
35. Purba J.S., Hoogendijk W.J., Hofman M.A., and Swaab D.F. Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression. Arch. Gen. Psychiatry 53 (1996) 137-143
36. Scantamburlo G., Hansenne M., Fuchs S., Pitchot W., Maréchal P., Pequeux C., Ansseau M., and Legros J.J. Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology 32 (2007) 407-410
37. Shaver P.R., Schachner D.A., and Mikulincer M. Attachment style, excessive reassurance seeking, relationship processes, and depression. Pers. Soc. Psychol. Bull. 31 (2005) 343-359
38. Shear K., Jin R., Ruscio A.M., Walters E.E., and Kessler R.C. Prevalence and correlates of estimated DSM-IV child and adult separation anxiety disorder in the National Comorbidity Survey Replication. Am. J. Psychiatry 163 (2006) 1074-1083
39. Stephens M., and Donnelly P. A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet. 73 (2003) 1162-1169
40. Swaab D.F., Bao A.M., and Lucassen P.J. The stress system in the human brain in depression and neurodegeneration. Ageing Res. Rev. 4 (2005) 141-194
41. Uvnäs-Moberg K. Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology 23 (1998) 819-835
42. Van Ijzendoorn M.H., and Bakermans-Kranenburg M.J. DRD4 7-repeat polymorphism moderates the association between maternal unresolved loss or trauma and infant disorganization. Attach. Hum. Dev. 8 (2006) 291-307
43. Van Londen, Goekoop J.G., van Kempen G.M., Frankhuijzen-Sierevogel A.C., Wiegant V.M., van der Velde E.A., and De Wied D. Plasma levels of arginine vasopressin elevated in patients with major depression. Neuropsychopharmacology 17 (1997) 284-292
44. Wang S.S., Kamphuis W., Huitinga I., Zhou J.N., and Swaab D.F. Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances. Mol. Psychiatry 13 (2008) 786-799
45. Weiss K.M., and Clark A.G. Linkage disequilibrium and the mapping of complex human traits. Trends Genet. 18 (2002) 19-24
46. Wu S., Jia M., Ruan Y., Liu J., Guo Y., Shuang M., Gong X., Zhang Y., Yang X., and Zhang D. Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol. Psychiatry 58 (2005) 74-77
47. Young R.C., Biggs J.T., Ziegler V.E., and Meger D.A. A racing scale for mania: reliability, validity and sensitivity. Br. J. Psychiatry 133 (1978) 429-433
48. Zetzsche T., Frasch A., Jirikowski G., Murck H., and Steigner A. Nocturnal oxytocin secretion is reduced in major depression. Biol. Psychiatry 39 (1996) 584