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Volumn 106, Issue 50, 2009, Pages 21437-21441

Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans

Author keywords

Emotional; Polymorphism; Social

Indexed keywords

OXYTOCIN; OXYTOCIN RECEPTOR;

EID: 75849116589     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909579106     Document Type: Article
Times cited : (629)

References (44)
  • 1
    • 31444453954 scopus 로고    scopus 로고
    • Dendritic peptide release and peptide-dependent behaviours
    • Ludwig M, Leng G (2006) Dendritic peptide release and peptide-dependent behaviours. Nature Rev 7:126-136.
    • (2006) Nature Rev , vol.7 , pp. 126-136
    • Ludwig, M.1    Leng, G.2
  • 2
    • 45549103898 scopus 로고    scopus 로고
    • Brain oxytocin: A key regulator of emotional and social behaviours in both females and males
    • Neumann ID (2008) Brain oxytocin: A key regulator of emotional and social behaviours in both females and males. J Neuroendocrinol 20:858-865.
    • (2008) J Neuroendocrinol , vol.20 , pp. 858-865
    • Neumann, I.D.1
  • 4
    • 0035069755 scopus 로고    scopus 로고
    • The oxytocin receptor system: Structure, function, and regulation
    • Gimpl G, Fahrenholz F (2001) The oxytocin receptor system: Structure, function, and regulation. Physiol Rev 81:629-683.
    • (2001) Physiol Rev , vol.81 , pp. 629-683
    • Gimpl, G.1    Fahrenholz, F.2
  • 5
    • 55849119537 scopus 로고    scopus 로고
    • Oxytocin, vasopressin, and the neurogenetics of sociality
    • Donaldson ZR, Young LJ (2008) Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322:900-904.
    • (2008) Science , vol.322 , pp. 900-904
    • Donaldson, Z.R.1    Young, L.J.2
  • 6
    • 0036454227 scopus 로고    scopus 로고
    • Involvement of the brain oxytocin system in stress coping: Interactions with the hypothalamo-pituitary-adrenal axis
    • Neumann ID (2002) Involvement of the brain oxytocin system in stress coping: Interactions with the hypothalamo-pituitary-adrenal axis. Progress Brain Res 139:147-162.
    • (2002) Progress Brain Res , vol.139 , pp. 147-162
    • Neumann, I.D.1
  • 7
    • 0035256912 scopus 로고    scopus 로고
    • The neurobiology of attachment
    • Insel TR, Young LJ (2001) The neurobiology of attachment. Nature Rev 2:129-136.
    • (2001) Nature Rev , vol.2 , pp. 129-136
    • Insel, T.R.1    Young, L.J.2
  • 8
    • 42649145854 scopus 로고    scopus 로고
    • Oxytocin increases generosity in humans
    • Zak PJ, Stanton AA, Ahmadi S (2007) Oxytocin increases generosity in humans. PloS One 2:e1128.
    • (2007) PloS One , vol.2
    • Zak, P.J.1    Stanton, A.A.2    Ahmadi, S.3
  • 10
  • 12
    • 35349010189 scopus 로고    scopus 로고
    • Evidence for a neuroendocrinological foundation of human affiliation: Plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding
    • Feldman R, Weller A, Zagoory-Sharon O, Levine A (2007) Evidence for a neuroendocrinological foundation of human affiliation: Plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding. Psychol Sci 18:965-970.
    • (2007) Psychol Sci , vol.18 , pp. 965-970
    • Feldman, R.1    Weller, A.2    Zagoory-Sharon, O.3    Levine, A.4
  • 14
    • 67649635332 scopus 로고    scopus 로고
    • Empathy toward strangers triggers oxytocin release and subsequent generosity
    • Barraza JA, Zak PJ (2009) Empathy toward strangers triggers oxytocin release and subsequent generosity. Ann N Y Acad Sci 1167:182-189.
    • (2009) Ann N Y Acad Sci , vol.1167 , pp. 182-189
    • Barraza, J.A.1    Zak, P.J.2
  • 15
    • 33748093784 scopus 로고    scopus 로고
    • The neuroscience of affiliation: Forging links between basic and clinical research on neuropeptides and social behavior
    • Bartz JA, Hollander E (2006) The neuroscience of affiliation: Forging links between basic and clinical research on neuropeptides and social behavior. Hormones Behav 50:518-528.
    • (2006) Hormones Behav , vol.50 , pp. 518-528
    • Bartz, J.A.1    Hollander, E.2
  • 16
    • 63049110712 scopus 로고    scopus 로고
    • Psychological and metabolic stress: A recipe for accelerated cellular aging?
    • Epel ES (2009) Psychological and metabolic stress: A recipe for accelerated cellular aging? Hormones 8:7-22.
    • (2009) Hormones , vol.8 , pp. 7-22
    • Epel, E.S.1
  • 17
    • 59249090252 scopus 로고    scopus 로고
    • Disruption of fear memory through dual-hormone gene therapy
    • Rodrigues SM, Sapolsky RM (2009) Disruption of fear memory through dual-hormone gene therapy. Biol Psychiatry 65:441-444.
    • (2009) Biol Psychiatry , vol.65 , pp. 441-444
    • Rodrigues, S.M.1    Sapolsky, R.M.2
  • 18
    • 0347627798 scopus 로고    scopus 로고
    • Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
    • EhlertU
    • Heinrichs M, Baumgartner T, Kirschbaum C, EhlertU(2003) Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 54:1389-1398.
    • (2003) Biol Psychiatry , vol.54 , pp. 1389-1398
    • Heinrichs, M.1    Baumgartner, T.2    Kirschbaum, C.3
  • 19
    • 0345222472 scopus 로고    scopus 로고
    • Social isolation and cardiovascular disease: An atherosclerotic pathway?
    • Knox SS, Uvnas-Moberg K (1998) Social isolation and cardiovascular disease: An atherosclerotic pathway? Psychoneuroendocrinology 23:877-890.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 877-890
    • Knox, S.S.1    Uvnas-Moberg, K.2
  • 20
    • 35649025870 scopus 로고    scopus 로고
    • Oxytocin attenuates amygdala responses to emotional faces regardless of valence
    • Domes G, et al. (2007) Oxytocin attenuates amygdala responses to emotional faces regardless of valence. Biol Psychiatry 62:1187-1190.
    • (2007) Biol Psychiatry , vol.62 , pp. 1187-1190
    • Domes, G.1
  • 21
    • 47549116536 scopus 로고    scopus 로고
    • New aspects of oxytocin receptor function revealed by knockout mice: Sociosexual behaviour and control of energy balance
    • Nishimori K, et al. (2008) New aspects of oxytocin receptor function revealed by knockout mice: Sociosexual behaviour and control of energy balance. Progress Brain Res 170:79-90.
    • (2008) Progress Brain Res , vol.170 , pp. 79-90
    • Nishimori, K.1
  • 22
    • 27644476955 scopus 로고    scopus 로고
    • Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
    • Takayanagi Y, et al. (2005) Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci USA 102:16096-16101.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16096-16101
    • Takayanagi, Y.1
  • 23
    • 21344444796 scopus 로고    scopus 로고
    • Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population
    • Wu S, et al. (2005) Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry 58:74-77.
    • (2005) Biol Psychiatry , vol.58 , pp. 74-77
    • Wu, S.1
  • 24
    • 45149102502 scopus 로고    scopus 로고
    • Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting
    • Bakermans-Kranenburg MJ, van Ijzendoorn MH (2008) Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. Soc Cogn Affect Neurosci 3:128-134.
    • (2008) Soc Cogn Affect Neurosci , vol.3 , pp. 128-134
    • Bakermans-Kranenburg, M.J.1    van Ijzendoorn, M.H.2
  • 25
    • 0034223169 scopus 로고    scopus 로고
    • Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight
    • Taylor SE, et al. (2000) Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychol Rev 107:411-429.
    • (2000) Psychol Rev , vol.107 , pp. 411-429
    • Taylor, S.E.1
  • 26
    • 0037248788 scopus 로고    scopus 로고
    • Theory of mind and psychopathy: Can psychopathic individuals read the 'language of the eyes'?
    • Richell RA, et al. (2003) Theory of mind and psychopathy: Can psychopathic individuals read the 'language of the eyes'? Neuropsychologia 41:523-526.
    • (2003) Neuropsychologia , vol.41 , pp. 523-526
    • Richell, R.A.1
  • 27
    • 0035087628 scopus 로고    scopus 로고
    • The "Reading the Mind in the Eyes" Test revised version: A study with normal adults, and adults with Asperger syndrome or high-functioning autism
    • Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I (2001) The "Reading the Mind in the Eyes" Test revised version: A study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry Allied Disc 42:241-251.
    • (2001) J Child Psychol Psychiatry Allied Disc , vol.42 , pp. 241-251
    • Baron-Cohen, S.1    Wheelwright, S.2    Hill, J.3    Raste, Y.4    Plumb, I.5
  • 28
    • 60749102683 scopus 로고    scopus 로고
    • Age-related decline in mentalizing skills across adult life span
    • Pardini M, Nichelli PF (2009) Age-related decline in mentalizing skills across adult life span. Exp Aging Res 35:98-106.
    • (2009) Exp Aging Res , vol.35 , pp. 98-106
    • Pardini, M.1    Nichelli, P.F.2
  • 29
    • 3543119581 scopus 로고    scopus 로고
    • The empathy quotient: An investigation of adults with Asperger syndrome or high functioning autism, and normal sex differences
    • Baron-Cohen S, Wheelwright S (2004) The empathy quotient: An investigation of adults with Asperger syndrome or high functioning autism, and normal sex differences. J Autism Dev Disord 34:163-175.
    • (2004) J Autism Dev Disord , vol.34 , pp. 163-175
    • Baron-Cohen, S.1    Wheelwright, S.2
  • 30
    • 85043740534 scopus 로고
    • Measuring individual differences in empathy: Evidence for a multi-dimensional approach
    • Davis MH (1983) Measuring individual differences in empathy: Evidence for a multi-dimensional approach. J Personal Social Psychol 44:113-126.
    • (1983) J Personal Social Psychol , vol.44 , pp. 113-126
    • Davis, M.H.1
  • 31
    • 0024397805 scopus 로고
    • Neural systems involved in fear-potentiated startle
    • Davis M (1989) Neural systems involved in fear-potentiated startle. Ann N Y Acad Sci 563:165-183.
    • (1989) Ann N Y Acad Sci , vol.563 , pp. 165-183
    • Davis, M.1
  • 32
    • 0034597928 scopus 로고    scopus 로고
    • Fear and anxiety: Animal models and human cognitive psychophysiology
    • Lang PJ, Davis M, Ohman A (2000) Fear and anxiety: Animal models and human cognitive psychophysiology. J Affect Disord 61:137-159.
    • (2000) J Affect Disord , vol.61 , pp. 137-159
    • Lang, P.J.1    Davis, M.2    Ohman, A.3
  • 34
    • 47649083963 scopus 로고    scopus 로고
    • Impact of prosocial neuropeptides on human brain function
    • Meyer-Lindenberg A (2008) Impact of prosocial neuropeptides on human brain function. Prog Brain Res 170:463-470.
    • (2008) Prog Brain Res , vol.170 , pp. 463-470
    • Meyer-Lindenberg, A.1
  • 35
    • 0032020651 scopus 로고    scopus 로고
    • Relations between affect and personality:Supportfor the affect-level and affective-reactivity views
    • Gross JJ,SuttonSK, KetelaarT(1998) Relations between affect and personality:Supportfor the affect-level and affective-reactivity views. Personal Soc Psychol Bull 24:279-288.
    • (1998) Personal Soc Psychol Bull , vol.24 , pp. 279-288
    • Gross, J.J.1    Sutton, S.K.2    Ketelaar, T.3
  • 37
    • 63449098569 scopus 로고    scopus 로고
    • Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict
    • Ditzen B, et al. (2009) Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. Biol Psychiatry 65:728-731.
    • (2009) Biol Psychiatry , vol.65 , pp. 728-731
    • Ditzen, B.1
  • 38
    • 59849119626 scopus 로고    scopus 로고
    • Influence of a "warm touch" support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol
    • Holt-Lunstad J, Birmingham WA, Light KC (2008) Influence of a "warm touch" support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol. Psychosom Med 70:976-985.
    • (2008) Psychosom Med , vol.70 , pp. 976-985
    • Holt-Lunstad, J.1    Birmingham, W.A.2    Light, K.C.3
  • 39
    • 34047153763 scopus 로고    scopus 로고
    • Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism
    • Jacob S, et al. (2007) Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism. Neurosci Lett 417:6-9.
    • (2007) Neurosci Lett , vol.417 , pp. 6-9
    • Jacob, S.1
  • 40
    • 0024706409 scopus 로고
    • Relation of sympathy and personal distress to prosocial behavior: A multimethod study
    • Eisenberg N, et al. (1989) Relation of sympathy and personal distress to prosocial behavior: A multimethod study. J Personal Soc Psychol 57:55-66.
    • (1989) J Personal Soc Psychol , vol.57 , pp. 55-66
    • Eisenberg, N.1
  • 41
    • 33750492310 scopus 로고    scopus 로고
    • Respiratory sinus arrhythmia, emotion, and emotion regulation during social interaction
    • Butler EA, Wilhelm FH, Gross JJ (2006) Respiratory sinus arrhythmia, emotion, and emotion regulation during social interaction. Psychophysiology 43:612-622.
    • (2006) Psychophysiology , vol.43 , pp. 612-622
    • Butler, E.A.1    Wilhelm, F.H.2    Gross, J.J.3
  • 42
    • 0024118211 scopus 로고
    • The startle probe response: A new measure of emotion?
    • Vrana SR, Spence EL, Lang PJ (1988) The startle probe response: A new measure of emotion? J Abnorm Psychol 97:487-491.
    • (1988) J Abnorm Psychol , vol.97 , pp. 487-491
    • Vrana, S.R.1    Spence, E.L.2    Lang, P.J.3
  • 43
    • 0001782722 scopus 로고    scopus 로고
    • Self-report measurement of adult attachment: An integrative overview
    • eds Simpson JA, Rholes WS Guilford Press, New York, pp
    • Brennan KA, Clark CL, Shaver PR (1998) Self-report measurement of adult attachment: An integrative overview. Attachment Theory and Close Relationships, eds Simpson JA, Rholes WS (Guilford Press, New York), pp 46-76
    • (1998) Attachment Theory and Close Relationships , pp. 46-76
    • Brennan, K.A.1    Clark, C.L.2    Shaver, P.R.3
  • 44
    • 0025245673 scopus 로고
    • The Parental Bonding Instrument. A decade of research
    • Parker G (1990) The Parental Bonding Instrument. A decade of research. Soc Psychiatry Psychiatr Epidemiol 25:281-282.
    • (1990) Soc Psychiatry Psychiatr Epidemiol , vol.25 , pp. 281-282
    • Parker, G.1


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