GW0742, A high-affinity PPAR-β/δ agonist, inhibits acute lung injury in mice

Shock

Volumn 33, Issue 4, 2010, Pages 426-435

  Di Paola, Rosanna ^a   Crisafulli, Concetta ^b   Mazzon, Emanuela ^a   Esposito, Emanuela ^a   Paterniti, Irene ^b   Galuppo, Maria ^b   Genovese, Tiziana ^a,b   Thiemermann, Christoph ^c   Cuzzocrea, Salvatore ^a,b  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Apoptosis; Carrageenan; Cytokines; Lipid peroxidation; Pleurisy; PMNs

Indexed keywords

3 NITROTYROSINE; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; CARRAGEENAN; FAS LIGAND; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PROTEIN BAX; PROTEIN BCL 2; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; 3-NITROTYROSINE; DRUG DERIVATIVE; I KAPPA B; INDUCIBLE NITRIC OXIDE SYNTHASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NOS2 PROTEIN, MOUSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR RELA; TYROSINE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PLEURISY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SHAM PROCEDURE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; SECRETION;

ACUTE LUNG INJURY; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARRAGEENAN; I-KAPPA B PROTEINS; LIPID PEROXIDATION; LUNG; MALE; MICE; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; PLEURISY; PPAR DELTA; PPAR-BETA; PROTO-ONCOGENE PROTEINS C-BCL-2; THIAZOLES; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 77954703383     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181b8f2fb     Document Type: Article

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