A non-traumatic Staphylococcus aureus osteomyelitis model in pigs

In Vivo

Volumn 24, Issue 3, 2010, Pages 257-264

  Jensen, Henrik Elvang ^a   Nielsen, Ole Lerberg ^a   Agerholm, Jørgen Steen ^a   Iburg, Tine ^a   Johansen, Louise Kruse ^a   Johannesson, Eleonora ^a   Møller, Maiken ^a   Jahn, Line ^a   Munk, Liselotte ^a   Aalbæk, Bent ^a   Leifsson, Pall Skuli ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Osteomyelitis; Pig; Porcine model; Pyaemia; Staphylococcus aureus

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; EXPERIMENTAL INFECTION; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; NONHUMAN; OSTEOMYELITIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SWINE;

EID: 77954106824     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Marriott I, Gray DL, Rati DM, Fowler VGJr, Stryjewski ME, Levin LS, Hudson, MC and Bost KL: Osteoblasts produce monocyte chemoattractant protein-1 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. Bone 37: 504-512, 2005.
2. Gelfan MS, Cleveland KO, Heck RK and Goswami R: Pathological fracture in acute osteomyelitis of long bones secondary to community-acquired methicillin-resistant Staphylococcus aureus: two cases and review of the literature. Am J Med Sci 332: 357-360, 2006.
3. Lazzarini L, Mader JT and Calhoun JH: Osteomyelitis in long bones. J Bone Joint Surg 56: 2305-2318, 2004.
4. Goergens ED, McEvoy A, Watson M and Barrett IR: Acute ostomyelitis and septic arthritis in children. J Paediatr Child Health 41: 59-62, 2005.
5. Liljegren CH, Aalbæk B, Nielsen OL and Jensen HE: Some new aspects of the pathology, pathogenesis, and aetiology of disseminated lung lesions in pigs. APMIS 111: 531-538, 2003.
6. Jensen HE, Jensen B, Ambjerg J and Aalbæk B: Chronic purulent osteomyelitis complicated by chondritis at the costochondral junction of slaughter pigs. Eur J Vet Pathol 5: 3-7, 1999.
7. An YH, Kang QK and Arciola CR: Animal models of osteomyelitis. Int J Artif Organs 29: 407-420, 2006.
8. Morris TH: Antibiotic therapeutics in laboratory animals. Lab Anim 29: 16-36, 1995.
9. Speers DJ and Nade SML: Ultrastructural studies of adherence of Staphylococcus aureus in experimental acute hematogenous osteomyelitis. Infec Immun 49: 443-446, 1985.
10. Deysine M, Rosario E and Isenberg HD: Acute hematogenous osteomyelitis: an experimental model. Surgery 79: 97-99, 1976. (Pubitemid 8006961)
11. Fukushima N, Yokoyama K, Sasahara T, Dobashi Y and Itoman M: Establishment of rat model of acute staphylococcal osteomyelitis: relationship between inoculation dose and development of osteomyelitis. Arch Orthop Traum Surg 125: 169-176, 2005.
12. Zak O and Sande MA: Introduction: the role of animal models in the evaluation of new antibiotics. In: Experimental Models in Antimicrobial Chemotherapy, Vol I. Zak O and Sande MA (eds.). Orlando: Academic Press, pp. 1-5, 1986.
13. Koschmieder R, Ritzerfeld W and Homeyer L: Gentamycinzusatz zum Polymethylmethacrylat zur Behandlung von Knocheninfektionen. Zeitschr Orthop Grenzgeb 113: 147-149, 1975.
14. Patterson AL, Galloway RH, Baumgartner JC and Barsoum IS: Development of chronic mandibular osteomyelitis in a mini swine model. J Oral Maxillofac Surg 51: 1358-1362, 1993.
15. Ball RO, House JD, Wykes LJ and Pencharz PB: A piglet model for neonatal amino acid metabolism during total parenteral nutrition. In: Advances in Swine in Biomedical Research, Vol. 2. Tumbleson ME and Schook LB (eds.). New York: Plenum Press pp. 713-731, 1996.
16. Hau J: Animal models. In: Handbook of Laboratory Animal Science, Vol 2. Hau J and Van Hoosier GL (eds.). Orlando; CRC Press, pp. 1-9, 2003.
17. Harris DL and Alexander TJL: Methods of Disease Control. In: Diseases of Swine (8th edn). Straw BE, Dállaire SY, Mengeling WL and Taylor DJ (eds.). Iowa: Iowa State University Press, pp. 1077-1110, 1999.
18. Nielsen OL, Iburg T, Aalbaek B, Leifsson PS, Agerholm JS, Heegaard P, Boye M, Simon S, Jensen KB, Christensen, S, Meisen K, Bak AK, Backman ER, Jørgensen MH, Groegler DK, Jensen AL, Kjelgaard-Hansen M and Jensen HE: A pig model of acute Staphylococcus aureus- induced pyemia. Acta Vet Scand 57: 1-6, 2009.
19. Sambrook J and Russell DW: Molecular Cloning. A Laboratory Manual, (3rd edn.), Vol. 3., appendix A2.2. New York: Cold Spring Harbor Laboratory Press, 2001.
20. Bancroft JD and Stevens A: Theory and Practice of Histological Techniques (4th edn.). New York: Churchill Livingstone, 1996.
21. Lew DP and Waldvogel FA: Osteomyelitis. Lancet 364: 369-379, 2004.
22. Weisbrode SE: Bone and Joints. In: Pathologic Basis of Veterinary Diseases (4th edn.). McGavin MD and Zachary F (eds). St. Louis: Mosby Elsevier, pp. 1041-1105, 2007.
23. Alderson M, Speers D, Emslie K and Nade S: Acute hematogenous osteomyelitis and septic arthritis - a single disease. A hypothesis based upon the presence of transphyseal blood vessels. J Bone Joint Surg 68: 268-274, 1986. (Pubitemid 16155786)
24. Rissing JP, Buxton TB, Fisher J, Harris R and Shockley RK: Arachidonic acid facilitates experimental chronic osteomyelitis in rats. Infec Immun 49: 141-144, 1985. (Pubitemid 15062881)
25. Reott MA, Ritchie-Miller SL, Anguita J and Hudson MC: TRAIL expression is induced in both osteoblasts containing intracellular Staphylococcus aureus and uninfected osteoblasts in infected cultures. FEMS Microbiol Lett 278: 185-192, 2008.
26. Dehring DJ, Crocker SH, Wismar BL, Steinberg SM, Lowery BD and Cloutier CT: Comparison of live bacteria infusion in a porcine model of acute respiratory failure. J Surg Res 34: 151-158, 1983.
27. Carek PJ, Dickerson LM and Sack JL: Diagnosis and management of osteomyelitis. Am Fam Physician 63: 2413-1420, 2001.
28. Bearman GML and Wenzel RP: Bacteremias: A leading cause of death. Arch Med Res 36: 646-659, 2005.
29. Yao L, Berman JW, Factor SM and Lowy FD: Correlation of histopathologic and bacteriologic changes with cytokine expression in an experimental murine model of bacteremic Staphylococcus aureus infection. Infec Immun 65: 3889-3895, 1997.
30. Davis JS: Management of bone and joint infections due to Staphylococcus aureus. Intern Med J 35(Suppl 2): 79-96, 2005.
31. Sia IG and Berbari EF: Osteomyelitis. Best Pract Res Clin Rheumatol 20: 1065-1081, 2006.
32. Ciampolini J and Harding KG: Pathophysiology of chronic bacterial osteomyelitis. Why do antibiotics fail so often? Postgrad Med J 76: 479-483, 2000.
33. Miwa K, Fukuyama M, Matsuno N, Masuda S, Oyama Y, Ikeda K and Ikeda T: Superantigen-induced multiple organ dysfunction in a toxin-concentration- controlled and sequential parameter-monitored swine sepsis model. Inter J Infec Dis 10: 14-24, 2006.