Age dependence of expression of growth factor receptors in porcine ACL fibroblasts

Journal of Orthopaedic Research

Volumn 28, Issue 8, 2010, Pages 1107-1112

  Vavken, Patrick ^a   Saad, Fawzy A ^a   Murray, Martha M ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

ACL repair; Gene expression; Growth factor receptor; Platelet rich plasma; Tissue engineering

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VASCULOTROPIN RECEPTOR;

AGE DISTRIBUTION; ANIMAL CELL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; AGING; ANIMAL; BIOSYNTHESIS; CYTOLOGY; METABOLISM; THROMBOCYTE RICH PLASMA;

AGING; ANIMALS; ANTERIOR CRUCIATE LIGAMENT; FEMALE; PLATELET-RICH PLASMA; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SWINE;

EID: 77954693470     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21111     Document Type: Article

References (39)

1. Louboutin H, Debarge R, Richou J, et al. 2009. Osteoarthritis in patients with anterior cruciate ligament rupture: a review of risk factors. Knee 16:239-244.
2. Oiestad BE, Engebretsen L, Storheim K, et al. 2009. Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med 37:1434-1443.
3. Gillquist J, Messner K. 1999. Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med 27:143-156. (Pubitemid 29184727)
4. Lohmander LS, Ostenberg A, Englund M, et al. 2004. High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury. Arthritis Rheum 50:3145-3152. (Pubitemid 39371990)
5. Meunier A, Odensten M, Good L. 2007. Long-term results after primary repair or non-surgical treatment of anterior cruciate ligament rupture: a randomized study with a 15-year follow-up. Scand J Med Sci Sports 17:230-237.
6. von Porat A, Roos EM, Roos H. 2004. High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes. Ann Rheum Dis 63:269-273. (Pubitemid 38250669)
7. Murray MM. 2009. Current status and potential of primary ACL repair. Clin Sports Med 28:51-61.
8. Vavken P, Murray MM. 2009. Translational studies in ACL repair. Tissue Eng Part A. (E-pub ahead of print).
9. Murray MM, Martin SD, Spector M. 2000. Migration of cells from human anterior cruciate ligament explants into collagen- glycosaminoglycan scaffolds. J Orthop Res 18:557-564.
10. Murray MM, Palmer M, Abreu E, et al. 2009. Platelet-rich plasma alone is not sufficient to enhance suture repair of the ACL in skeletally immature animals: an in vivo study. J Orthop Res 27:639-645.
11. Murray MM, Spector M. 2001. The migration of cells from the ruptured human anterior cruciate ligament into collagen-glycosaminoglycan regeneration templates in vitro. Biomaterials 22:2393-2402. (Pubitemid 32666230)
12. Murray MM, Spindler KP, Abreu E, et al. 2007. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res 25: 81-91. (Pubitemid 46070734)
13. Murray MM, Spindler KP, Ballard P, et al. 2007. Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen-platelet-rich plasma scaffold. J Orthop Res 25:1007-1017. (Pubitemid 47233077)
14. Murray MM, Spindler KP, Devin C, et al. 2006. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthop Res 24:820-830. (Pubitemid 43804978)
15. Fleming BC, Carey JL, Spindler KP, et al. 2008. Can suture repair of ACL transection restore normal anteroposterior laxity of the knee? An ex vivo study. J Orthop Res 26:1500-1505.
16. Fleming BC, Spindler KP, Palmer M, et al. 2009. Collagen-platelet composites improve the biomechanical properties of healing ACL grafts in a porcine model. AJSM 37:1554-1563.
17. Spindler KP, Murray MM, Carey JL, et al. 2009. The use of platelets to affect functional healing of an anterior cruciate ligament (ACL) autograft in a caprine ACL reconstruction model. J Orthop Res 27:631-638.
18. Anitua E, Sanchez M, Nurden AT, et al. 2006. Autologous fibrin matrices: a potential source of biological mediators that modulate tendon cell activities. J Biomed Mater Res A 77: 285-293. (Pubitemid 47233530)
19. Creaney L, Hamilton B. 2008. Growth factor delivery methods in the management of sports injuries: the state of play. Br J Sports Med 42:314-320. (Pubitemid 351702675)
20. Eppley BL, Woodell JE, Higgins J. 2004. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg 114: 1502-1508. (Pubitemid 40361959)
21. Sanchez M, Anitua E, Azofra J, et al. 2007. Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35:245-251. (Pubitemid 46145405)
22. Mastrangelo A, Magarian E, Palmer M, et al. 2009. The effect of skeletal maturity on the regenerative function of intrinsic ACL cells. J Orthop Res (E-pub ahead of print).
23. Mastrangelo A, Haus B, Vavken P, et al. 2009. Immature animals have denser anterior cruciate ligament wound site cell repopulation than adolescent or adult animals. J Orthop Res (in press).
24. Everts PA, Knape JT, Weibrich G, et al. 2006. Platelet-rich plasma and platelet gel: a review. J Extra Corpor Technol 38:174-187. (Pubitemid 351506605)
25. Weibrich G, Kleis WK, Hafner G, et al. 2002. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 30:97-102. (Pubitemid 34846492)
26. Hofstaetter JG, Saad FA, Samuel RE, et al. 2004. Differential expression of VEGF isoforms and receptors in knee joint menisci under systemic hypoxia. Biochem Biophys Res Commun 324:667-672.
27. Hofstaetter JG, Wunderlich L, Samuel RE, et al. 2005. Systemic hypoxia alters gene expression levels of structural proteins and growth factors in knee joint cartilage. Biochem Biophys Res Commun 330:386-394. (Pubitemid 40417658)
28. van den Dolder J, Mooren R, Vloon AP, et al. 2006. Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells. Tissue Eng 12:3067-3073. (Pubitemid 44846412)
29. Murray M, Rice K, Wright RJ, et al. 2003. The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold. J Orthop Res 21:238-244. (Pubitemid 36322542)
30. El-Sharkawy H, Kantarci A, Deady J, et al. 2007. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol 78:661-669.
31. Bonner JC, Badgett A, Lindroos PM, et al. 1995. Transforming growth factor beta 1 downregulates the platelet-derived growth factor alpha-receptor subtype on human lung fibroblasts in vitro. Am J Respir Cell Mol Biol 13:496-505.
32. Ichiki Y, Smith E, LeRoy EC, et al. 1995. Different effects of basic fibroblast growth factor and transforming growth factorbeta on the two platelet-derived growth factor receptors' expression in scleroderma and healthy human dermal fibroblasts. J Invest Dermatol 104:124-127.
33. Messadi DV, Le A, Berg S, et al. 1998. Effect of TGF-beta 1 on PDGF receptors expression in human scar fibroblasts. Front Biosci 3:a16-a22.
34. Altman DG, Royston P. 2006. The cost of dichotomising continuous variables. Br Med J 332:1080.
35. Royston P, Altman DG, Sauerbrei W. 2006. Dichotomizing continuous predictors in multiple regression: a bad idea. Stat Med 25:127-141. (Pubitemid 43136953)
36. Petrova TV, Makinen T, Alitalo K. 1999. Signaling via vascular endothelial growth factor receptors. Exp Cell Res 253:117.
37. Clark DA, Coker R. 1998. Molecules in focus transforming growth factor-beta (TGF-[beta]). Int J Biochem Cell Biol 30:293.
38. Ellis IR, Schor SL. 1998. Differential mitogenic and biosynthetic response of fetal and adult skin fibroblasts to TGF-beta isoforms. Cytokine 10:281-289.
39. Kottler UB, Junemann AG, Aigner T, et al. 2005. Comparative effects of TGF-beta 1 and TGF-beta 2 on extracellular matrix production, proliferation, migration, and collagen contraction of human Tenon's capsule fibroblasts in pseudoexfoliation and primary open-angle glaucoma. Exp Eye Res 80:121-134. (Pubitemid 40126520)