Dichotomizing continuous predictors in multiple regression: A bad idea

Statistics in Medicine

Volumn 25, Issue 1, 2006, Pages 127-141

  Royston, Patrick ^a   Altman, Douglas G ^b   Sauerbrei, Willi ^c  

^a MRC CLINICAL TRIALS UNIT   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Categorization; Clinical research; Continuous covariates; Dichotomization; Efficiency; Regression

Indexed keywords

AZATHIOPRINE; BILIRUBIN; PLACEBO;

ALGORITHM; ARTICLE; CLINICAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COVARIANCE; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE REGRESSION; PRIMARY BILIARY CIRRHOSIS; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STATISTICAL MODEL; SURVIVAL TIME; TREATMENT OUTCOME; TREATMENT RESPONSE; VALIDATION PROCESS;

AGE FACTORS; ALBUMINS; ANTIMETABOLITES; AZATHIOPRINE; BILIRUBIN; CHOLESTASIS; DATA INTERPRETATION, STATISTICAL; HUMANS; LIVER CIRRHOSIS, BILIARY; RANDOMIZED CONTROLLED TRIALS; REGRESSION ANALYSIS;

EID: 31344435149     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.2331     Document Type: Article

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