Enhanced 1,3-propanediol production by supply of organic acids and repeated fed-batch culture

Journal of Industrial Microbiology and Biotechnology

Volumn 37, Issue 7, 2010, Pages 681-687

  Xue, Xuedong ^a   Li, Wei ^a   Li, Zhimin ^a   Xia, Yuelan ^a   Ye, Qin ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

1,3 Propanediol; Klebsiella pneumoniae; Organic acid mixture; Repeated fed batch culture

Indexed keywords

1,3 PROPANEDIOL; ACETIC ACID; ALCOHOL; CARBOXYLIC ACID; CITRIC ACID; FUMARIC ACID; GLYCEROL; LACTIC ACID; SUCCINIC ACID; 1,3-PROPANEDIOL; PROPANEDIOL DERIVATIVE;

ARTICLE; BIOREACTOR; CELL DENSITY; CELL GROWTH; FED BATCH CULTURE; KLEBSIELLA PNEUMONIAE; NONHUMAN; CULTURE TECHNIQUE; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY;

ACIDS, ACYCLIC; BIOREACTORS; CULTURE TECHNIQUES; FERMENTATION; KLEBSIELLA PNEUMONIAE; PROPYLENE GLYCOLS;

KLEBSIELLA PNEUMONIAE;

EID: 77954690511     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-010-0711-z     Document Type: Article

References (23)

1. Biebl H, Menzel K, Zeng AP, Deckwer WD (1999) Microbial production of PDO. Appl Microbiol Biotechnol 52:289-297
2. Zeng AP, Biebl H (2002) Bulk chemicals from biotechnology: the case of PDO production and the new trends. Adv Biochem Eng Biotechnol 74:239-259
3. Reimann A, Biebl H, Deckwer WD (1998) Production of 1,3 propanediol by Clostridium butyricum in continuous culture with cell recycling. Appl Microbiol Biotechnol 49:359-363
4. El-Ziney MG, Arneborg N, Uyttendaele M, Debevere J, Jakobsen M (1998) Characterization of growth and metabolite production of Lactobacillus reuteri during glucose/glycerol fermentation in batch and continuous cultures. Biotechnol Lett 20:913-916
5. Biebl H (1991) Glycerol fermentation to PDO by Clostridium butyricum: measurement of product inhibition by use of a pHauxostat. Appl Microbiol Biotechnol 35:701-705
6. Menzel K, Ahrens K, Zeng AP, Deckwer WD (1998) Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: IV. Enzymes and fluxes of pyruvate metabolism. Biotechnol Bioeng 60:617-626 (Pubitemid 28498604)
7. Colin T, Bories A, Moulin G (2000) Inhibition of Clostridium butyricun by PDO and diols during glycerol fermentation. Appl Microbiol Biotechnol 54:201-205
8. Huang H, Gong CS, Tsao GT (2002) Production of 1,3-propanediol by Klebsiella pneumoniae. Appl Biochem Biotechnol 98:687-698
9. Menzel K, Zeng AP, Deckwer WD (1997) Hight concentration and productivity of PDO from continuous fermentation of glycerol by Klebsiella pneumoniae. Enzyme Microb Technol 20:82-86
10. Ji XJ, Huang H, Zhu JG, Hu N, Li S (2009) Efficient PDO production by fed-batch culture of Klebsiella pneumoniae: the role of pH fluctuation. Appl Biochem Biotechnol 159:605-613
11. Zheng ZM, Hu QL, Hao J, Xu F, Guo N, Sun Y, Liu DH (2008) Statistical optimization of culture conditions for PDO by Klebsiella pneumoniae AC15 via central composite design. Bioresour Technol 5:1052-1056
12. Cheng KK, Liu HJ, Liu DH (2005) Multiple growth inhibition of Klebsiella pneumoniae in PDO fermentation. Biotechnol Lett 27:19-22
13. Zeng AP, Menzel K, Deckwer WD (1996) Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: II analysis of metabolic rates and pathways under oscillation and steady-state conditions. Biotechnol Bioeng 52:561-571
14. Yang G, Tian J, Li J (2007) Fermentation of PDO by a lactate deficient mutant of Klebsiella oxytoca under microaerobic conditions. Appl Microbiol Biotechnol 73:1017-1024
15. Zhang YP, Liu M, Du CY, Shen JY, Cao ZA (2006) Effect of byproducts on cell growth and biosynthesis of PDO by Klebsiella pneumoniae. Chin J Proc Eng 6:804-808 (in Chinese)
16. Lin RH, Liu HJ, Hao J, Cheng KK, Liu DH (2005) Enhancement of PDO production by Klebsiella pneumoniae with fumarate addition. Biotechnol Lett 27:1755-1759
17. Wan HM, Chen CC, Giridhar R, Chang TS, Wu WT (2005) Reapeated-bach production of kojic acid in a cell-retention fermenter using Aspergillus oryzae M3B9. J Ind Microbiol Biotechnol 32:227-233
18. Ito T, Sota H, Honda H, Shimizu K, Kobayashi T (1991) Efficient acetic acid production by repeated fed-batch fermentation using two fermentors. Appl Microbiol Biotechnol 36:295-299
19. Bradford P, Pohle WD, Gunther JK, Mehlenbacher VC (1942) Determination of glycerol by oxidation with periodic acid. Oil Soap 19:189-193
20. Fond O, Jansen NB, Tsao GT (1985) A model of acetate and 2,3- butanediol inhibition of the growth and metabolism of Klebsiella oxytoca. Biotechnol Lett 7:727-732
21. Guan GP, Wang HB, Tian JH (2008) Effect of succinate on aerobic fermentation of 1,3-propanediol from glycerol by Klebsiella oxytaca. Food Ferment Ind 34(5):14-17 (in Chinese)
22. Wang LM, Gan RY, Jin P, Dong MY (2006) Effect of some organic acids on cell growth and 1,3-propanediol production. Fine Chem 5:439-442 (in Chinese)
23. Nelson DL, Cox MM (2000) Lehninger principles of biochemistry, 3rd edn. Worth Publishers, New York