Influence of hypoxia induced by minimally invasive prostatectomy on gene expression: Implications for biomarker analysis

American Journal of Translational Research

Volumn 2, Issue 3, 2010, Pages 210-222

  Erickson, Heidi S ^a,b   Josephson, John W ^b   Vira, Manish ^b,c   Albert, Paul S ^d   Gillespie, John W ^e   Rodriguez Canales, Jaime ^b   Pinto, Peter A ^b   Chuaqui, Rodrigo F ^a   Emmert Buck, Michael R ^b   Coleman, Jonathan A ^b,f  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c The Arthur Smith Institute for Urology   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e SAIC FREDERICK INC   (United States)

^f MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Gene expression analysis; Hypoxia; Laparoscopic surgery; Prostatectomy; Tissue microdissection; Warm ischemia

Indexed keywords

5 METHYLTETRAHYDROFOLATE HOMOCYSTEINE METHYLTRANSFERASE; BETA ACTIN; BIOLOGICAL MARKER; CYCLOPHILIN A; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MESSENGER RNA; PROSTATE SPECIFIC ANTIGEN; RNA 18S; STAT5B PROTEIN; TRANSFERRIN RECEPTOR; VASCULOTROPIN A; VON HIPPEL LINDAU PROTEIN;

ADULT; AGED; ARTICLE; BLEEDING; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GLEASON SCORE; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; ISCHEMIA; LAPAROSCOPIC SURGERY; MALE; MICRODISSECTION; MINIMALLY INVASIVE SURGERY; NUCLEOTIDE SEQUENCE; OPERATION DURATION; PROSTATE BIOPSY; PROSTATE CANCER; PROSTATECTOMY; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; STROMA CELL; URETHRA;

EID: 77954674283     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Emmert-Buck MR, Strausberg RL, Krizman DB, Bonaldo MF, Bonner RF, Bostwick DG, Brown MR, Buetow KH, Chuaqui RF, Cole KA, Duray PH, Englert CR, Gillespie JW, Greenhut S, Grouse L, Hillier LW, Katz KS, Klausner RD, Kuznetzov V, Lash AE, Lennon G, Linehan WM, Liotta LA, Marra MA, Munson PJ, Ornstein DK, Prabhu VV, Prange C, Schuler GD, Soares MB, Tolstoshev CM, Vocke CD and Waterston RH. Molecular Profiling of Clinical Tissue Specimens: Feasibility and Applications. J Mol Diagn 2000; 2: 60-66.
2. Chen CN, Lin JJ, Chen JJ, Lee PH, Yang CY, Kuo ML, Chang KJ and Hsieh FJ. Gene expression profile predicts patient survival of gastric cancer after surgical resection. J Clin Oncol 2005; 23: 7286-7295.
3. Almeida A, Paul Thiery J, Magdelenat H and Radvanyi F. Gene expression analysis by realtime reverse transcription polymerase chain reaction: influence of tissue handling. Analytical Biochemistry 2004; 328: 101-108.
4. Sorensen BS, Hao J, Overgaard J, Vorum H, Honore B, Alsner J and Horsman MR. Influence of oxygen concentration and pH on expression of hypoxia induced genes. Radiotherapy and Oncology 2005; 76: 187-193.
5. Dash A, Maine IP, Varambally S, Shen R, Chinnaiyan AM and Rubin MA. Changes in Differential Gene Expression because of Warm Ischemia Time of Radical Prostatectomy Specimens. Am J Pathol 2002; 161: 1743-1748.
6. Gillespie JW, Best CJM, Bichsel VE, Cole KA, Greenhut SF, Hewitt SM, Ahram M, Gathright YB, Merino MJ, Strausberg RL, Epstein JI, Hamilton SR, Gannot G, Baibakova GV, Calvert VS, Flaig MJ, Chuaqui RF, Herring JC, Pfeifer J, Petricoin EF, Linehan WM, Duray PH, Bova GS and Emmert-Buck MR. Evaluation of Non-Formalin Tissue Fixation for Molecular Profiling Studies. Am J Pathol 2002; 160: 449-457.
7. Erickson HS, Albert PS, Gillespie JW, Rodriguez-Canales J, Marston Linehan W, Pinto PA, Chuaqui RF and Emmert-Buck MR. Quantitative RT-PCR gene expression analysis of laser microdissected tissue samples. Nat Protoc 2009; 4: 902-922.
8. Erickson HS, Albert PS, Gillespie JW, Wallis BS, Rodriguez-Canales J, Linehan WM, Gonzalez S, Velasco A, Chuaqui RF and Emmert-Buck MR. Assessment of normalization strategies for quantitative RT-PCR using microdissected tissue samples. Lab Invest 2007; 87: 951-962.
9. Best CJ, Gillespie JW, Yi Y, Chandramouli GV, Perlmutter MA, Gathright Y, Erickson HS, Georgevich L, Tangrea MA, Duray PH, Gonzalez S, Velasco A, Linehan WM, Matusik RJ, Price DK, Figg WD, Emmert-Buck MR and Chuaqui RF. Molecular alterations in primary prostate cancer after androgen ablation therapy. Clin Cancer Res 2005; 11: 6823-6834.
10. Michiels C. Physiological and Pathological Responses to Hypoxia. Am J Pathol 2004; 164: 1875-1882.
11. Best CJ, Leiva IM, Chuaqui RF, Gillespie JW, Duray PH, Murgai M, Zhao Y, Simon R, Kang JJ, Green JE, Bostwick DG, Linehan WM and Emmert-Buck MR. Molecular differentiation of high-and moderate-grade human prostate cancer by cDNA microarray analysis. Diagn Mol Pathol 2003; 12: 63-70.
12. Zhu LJ and Altmann SW. mRNA and 18S-RNA coapplication-reverse transcription for quantitative gene expression analysis. Anal Biochem 2005; 345: 102-109.
13. Ohl F, Jung M, Radonic A, Sachs M, Loening SA and Jung K. Identification and validation of suitable endogenous reference genes for gene expression studies of human bladder cancer. J Urol 2006; 175: 1915-1920.
14. Schmid H, Cohen CD, Henger A, Irrgang S, Schlondorff D and Kretzler M. Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies. Kidney Int 2003; 64: 356-360.
15. Cohen CD, Frach K, Schlondorff D and Kretzler M. Quantitative gene expression analysis in renal biopsies: a novel protocol for a high throughput multi center application. Kidney Int 2002; 61: 133-140.
16. Livak KJ and Schmittgen TD. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-[Delta][Delta]CT Method. Methods 2001; 25: 402-408.
17. Fink L, Seeger W, Ermert L, Hanze J, Stahl U, Grimminger F, Kummer W and Bohle RM. Realtime quantitative RT-PCR after laser-assisted cell picking. Nat Med 1998; 4: 1329-1333.
18. Xu LL, Sun C, Petrovics G, Makarem M, Furusato B, Zhang W, Sesterhenn IA, McLeod DG, Sun L, Moul JW and Srivastava S. Quantitative expression profile of PSGR in prostate cancer. Prostate Cancer Prostatic Dis 2006; 9: 56-61.
19. Lin DW, Coleman IM, Hawley S, Huang CY, Dumpit R, Gifford D, Kezele P, Hung H, Knudsen BS, Kristal AR and Nelson PS. Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis. J Clin Oncol 2006; 24: 3763-3770.
20. Ghafar MA, Anastasiadis AG, Chen MW, Burchardt M, Olsson LE, Xie H, Benson MC and Buttyan R. Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells. Prostate 2003; 54: 58-67.
21. Vogt M, Puntschart A, Geiser J, Zuleger C, Billeter R and Hoppeler H. Molecular adaptations in human skeletal muscle to endurance training under simulated hypoxic conditions. J Appl Physiol 2001; 91: 173-182.
22. Wouters BG, Weppler SA, Koritzinsky M, Landuyt W, Nuyts S, Theys J, Chiu RK and Lambin P. Hypoxia as a target for combined modality treatments. European Journal of Cancer 2002; 38: 240-257.
23. Burroughs KD, Oh J, Barrett JC and DiAugustine RP. Phosphatidylinositol 3-Kinase and Mek1/2 Are Necessary for Insulin-Like Growth Factor-IInduced Vascular Endothelial Growth Factor Synthesis in Prostate Epithelial Cells: A Role for Hypoxia-Inducible Factor-1? Mol Cancer Res 2003; 1: 312-322.
24. Gao N, Ding M, Zheng JZ, Zhang Z, Leonard SS, Liu KJ, Shi X and Jiang B-H. Vanadate-induced Expression of Hypoxia-inducible Factor 1alpha and Vascular Endothelial Growth Factor through Phosphatidylinositol 3-Kinase/Akt Pathway and Reactive Oxygen Species. J. Biol. Chem. 2002; 277: 31963-31971.
25. Maynard MA and Ohh M. Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer. Am J Nephrol 2004; 24: 1-13.
26. Yang YM, Bost F, Charbono W, Dean N, McKay R, Rhim JS, Depatie C and Mercola D. C-Jun NH (2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma. Clin Cancer Res 2003; 9: 391-401.
27. Leiva IM, Emmert-Buck MR and Gillespie JW. Handling of clinical tissue specimens for molecular profiling studies. Curr Issues Mol Biol 2003; 5: 27-35.
28. Larkin JE, Frank BC, Gavras H, Sultana R and Quackenbush J. Independence and reproducibility across microarray platforms. Nat Methods 2005; 2: 337-344.