Requirement of NF-kappaB signalling pathway for modulation of the cholinergic muscarinic M3 receptor expression by INGAP-PP in insulin-producing cells

European Journal of Pharmacology

Volumn 642, Issue 1-3, 2010, Pages 37-46

  Paula, Flavia M M ^a   Barbosa, Helena C L ^a   Carneiro, Everardo M ^a   Persaud, Shanta J ^b   Gagliardino, Juan J ^c   Boschero, Antonio C ^a   Souza, Kleber L A ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c University of La Plata CONICET   (Argentina)

Author keywords

Cholinergic receptor; Diabetes; Gene expression regulation; MAChR; Pseudoislet; Transcription factor

Indexed keywords

BETA ACTIN; CALCIUM; CYCLINE; ILOTROPIN DERIVED REG3 RELATED ISLET NEOGENESIS ASSOCIATED PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUSCARINIC M3 RECEPTOR; MYC PROTEIN; POLYPEPTIDE; PROTEIN KINASE B; PROTEIN P85; S6 KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ACETYLCHOLINE; CARBACHOL; CYTOKINE; INGAP PEPTIDE; PEPTIDE FRAGMENT; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA;

ARTICLE; CALCIUM CELL LEVEL; CELL PROLIFERATION; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DRUG MECHANISM; GENE EXPRESSION REGULATION; IN VITRO STUDY; INSULIN RELEASE; MITOSIS RATE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SERUM RESPONSIVE ELEMENT; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANIMAL; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; ENZYME ACTIVE SITE; GENE SILENCING; GENETICS; INTRACELLULAR SPACE; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; RAT; REPRODUCIBILITY; TUMOR CELL LINE; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCHOLINE; ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARBACHOL; CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYTOKINES; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; INSULIN-SECRETING CELLS; INTRACELLULAR SPACE; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MYC; RATS; RECEPTOR, MUSCARINIC M3; REPRODUCIBILITY OF RESULTS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, SMALL INTERFERING; SERUM RESPONSE ELEMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; UP-REGULATION; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77954620581     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.05.056     Document Type: Article

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