메뉴 건너뛰기




Volumn 49, Issue 12, 2006, Pages 2910-2919

Evidence for the homeostatic regulation of induced beta cell mass expansion

Author keywords

Beta cell mass; Beta cell neogenesis; Diabetes mellitus; Endogenous progenitor cell therapy; Islet neogenesis

Indexed keywords

GLUCOSE; ISLET NEOGENESIS ASSOCIATED PROTEIN 104 118; PROTEIN; UNCLASSIFIED DRUG;

EID: 33750908049     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-006-0428-8     Document Type: Article
Times cited : (15)

References (50)
  • 1
    • 0021251188 scopus 로고
    • The life story of the pancreatic B cell
    • Hellerstrom C (1984) The life story of the pancreatic B cell. Diabetologia 26:393-400
    • (1984) Diabetologia , vol.26 , pp. 393-400
    • Hellerstrom, C.1
  • 2
    • 0021777067 scopus 로고
    • Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited
    • Kloppel G, Lohr M, Habich K, Oberholzer M, Heitz PU (1985) Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited. Surv Synth Pathol Res 4:110-125
    • (1985) Surv Synth Pathol Res , vol.4 , pp. 110-125
    • Kloppel, G.1    Lohr, M.2    Habich, K.3    Oberholzer, M.4    Heitz, P.U.5
  • 4
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 5
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352:837-853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 6
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy
    • Writing team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group
    • Writing team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group (2003) Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy. JAMA 290:2159-2167
    • (2003) JAMA , vol.290 , pp. 2159-2167
  • 7
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA et al (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230-238
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3
  • 8
    • 0035085643 scopus 로고    scopus 로고
    • Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
    • Ryan EA, Lakey JR, Rajotte RV et al (2001) Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50:710-719
    • (2001) Diabetes , vol.50 , pp. 710-719
    • Ryan, E.A.1    Lakey, J.R.2    Rajotte, R.V.3
  • 9
    • 0035017734 scopus 로고    scopus 로고
    • Pancreas transplantation for treatment of diabetes mellitus
    • Sutherland DE, Gruessner RW, Gruessner AC (2001) Pancreas transplantation for treatment of diabetes mellitus. World J Surg 25:487-496
    • (2001) World J Surg , vol.25 , pp. 487-496
    • Sutherland, D.E.1    Gruessner, R.W.2    Gruessner, A.C.3
  • 10
    • 0038819981 scopus 로고    scopus 로고
    • Edmonton's islet success tough to duplicate elsewhere
    • Ault A (2003) Edmonton's islet success tough to duplicate elsewhere. Lancet 361:2054
    • (2003) Lancet , vol.361 , pp. 2054
    • Ault, A.1
  • 11
    • 21344462346 scopus 로고    scopus 로고
    • Five-year follow-up after clinical islet transplantation
    • Ryan EA, Paty BW, Senior PA et al (2005) Five-year follow-up after clinical islet transplantation. Diabetes 54:2060-2069
    • (2005) Diabetes , vol.54 , pp. 2060-2069
    • Ryan, E.A.1    Paty, B.W.2    Senior, P.A.3
  • 12
    • 24144446405 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice
    • Suarez-Pinzon WL, Yan Y, Power R, Brand SJ, Rabinovitch A (2005) Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice. Diabetes 54:2596-2601
    • (2005) Diabetes , vol.54 , pp. 2596-2601
    • Suarez-Pinzon, W.L.1    Yan, Y.2    Power, R.3    Brand, S.J.4    Rabinovitch, A.5
  • 13
    • 0036968693 scopus 로고    scopus 로고
    • Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin
    • Brand SJ, Tagerud S, Lambert P et al (2002) Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin. Pharmacol Toxicol 91:414-420
    • (2002) Pharmacol Toxicol , vol.91 , pp. 414-420
    • Brand, S.J.1    Tagerud, S.2    Lambert, P.3
  • 14
    • 7044241260 scopus 로고    scopus 로고
    • A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell mass and reverses diabetes in C57BL/6J mice
    • Rosenberg L, Lipsett M, Yoon JW et al (2004) A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell mass and reverses diabetes in C57BL/6J mice. Ann Surg 240:875-884
    • (2004) Ann Surg , vol.240 , pp. 875-884
    • Rosenberg, L.1    Lipsett, M.2    Yoon, J.W.3
  • 15
    • 0036310118 scopus 로고    scopus 로고
    • Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue
    • Rooman I, Lardon J, Bouwens L (2002) Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes 51:686-690
    • (2002) Diabetes , vol.51 , pp. 686-690
    • Rooman, I.1    Lardon, J.2    Bouwens, L.3
  • 16
    • 27744481287 scopus 로고    scopus 로고
    • Metaplasia in the pancreas
    • Lardon J, Bouwens L (2005) Metaplasia in the pancreas. Differentiation 73:278-286
    • (2005) Differentiation , vol.73 , pp. 278-286
    • Lardon, J.1    Bouwens, L.2
  • 17
    • 0001334566 scopus 로고
    • Nesidioblastoma, the islet tumor of the pancreas
    • Laidlaw GF (1938) Nesidioblastoma, the islet tumor of the pancreas. Am J Pathol 14:125-139
    • (1938) Am J Pathol , vol.14 , pp. 125-139
    • Laidlaw, G.F.1
  • 18
    • 0028876097 scopus 로고
    • Multiple genetic alterations in malignant metastatic insulinomas
    • Pavelic K, Hrascan R, Kapitanovic S et al (1995) Multiple genetic alterations in malignant metastatic insulinomas. J Pathol 177:395-400
    • (1995) J Pathol , vol.177 , pp. 395-400
    • Pavelic, K.1    Hrascan, R.2    Kapitanovic, S.3
  • 19
    • 0031787342 scopus 로고    scopus 로고
    • Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice
    • Wagner M, Luhrs H, Kloppel G, Adler G, Schmid RM (1998) Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice. Gastroenterology 115:1254-1262
    • (1998) Gastroenterology , vol.115 , pp. 1254-1262
    • Wagner, M.1    Luhrs, H.2    Kloppel, G.3    Adler, G.4    Schmid, R.M.5
  • 21
    • 0028985830 scopus 로고
    • Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: Effect of lactogenic hormones
    • Parsons JA, Bartke A, Sorenson RL (1995) Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: effect of lactogenic hormones. Endocrinology 136:2013-2021
    • (1995) Endocrinology , vol.136 , pp. 2013-2021
    • Parsons, J.A.1    Bartke, A.2    Sorenson, R.L.3
  • 22
    • 0028845665 scopus 로고
    • Apoptosis contributes to the involution of beta cell mass in the post partum rat pancreas
    • Scaglia L, Smith FE, Bonner-Weir S (1995) Apoptosis contributes to the involution of beta cell mass in the post partum rat pancreas. Endocrinology 136:5461-5468
    • (1995) Endocrinology , vol.136 , pp. 5461-5468
    • Scaglia, L.1    Smith, F.E.2    Bonner-Weir, S.3
  • 23
    • 0035863007 scopus 로고    scopus 로고
    • Postnatal mammary gland morphogenesis
    • Silberstein GB (2001) Postnatal mammary gland morphogenesis. Microsc Res Tech 52:155-162
    • (2001) Microsc Res Tech , vol.52 , pp. 155-162
    • Silberstein, G.B.1
  • 24
    • 0035862998 scopus 로고    scopus 로고
    • Apoptosis in normal and neoplastic mammary gland development
    • Strange R, Metcalfe T, Thackray L, Dang M (2001) Apoptosis in normal and neoplastic mammary gland development. Microsc Res Tech 52:171-181
    • (2001) Microsc Res Tech , vol.52 , pp. 171-181
    • Strange, R.1    Metcalfe, T.2    Thackray, L.3    Dang, M.4
  • 25
    • 0033111697 scopus 로고    scopus 로고
    • Introduction: Mammary gland involution and apoptosis of mammary epithelial cells
    • Furth PA (1999) Introduction: mammary gland involution and apoptosis of mammary epithelial cells. J Mammary Gland Biol Neoplasia 4:123-127
    • (1999) J Mammary Gland Biol Neoplasia , vol.4 , pp. 123-127
    • Furth, P.A.1
  • 26
    • 0035862992 scopus 로고    scopus 로고
    • Vascular remodelling during the normal and malignant life cycle of the mammary gland
    • Djonov V, Andres AC, Ziemiecki A (2001) Vascular remodelling during the normal and malignant life cycle of the mammary gland. Microsc Res Tech 52:182-189
    • (2001) Microsc Res Tech , vol.52 , pp. 182-189
    • Djonov, V.1    Andres, A.C.2    Ziemiecki, A.3
  • 28
    • 0030054222 scopus 로고    scopus 로고
    • Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways
    • Li M, Hu J, Heermeier K, Hennighausen L, Furth PA (1996) Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways. Cell Growth Differ 7:13-20
    • (1996) Cell Growth Differ , vol.7 , pp. 13-20
    • Li, M.1    Hu, J.2    Heermeier, K.3    Hennighausen, L.4    Furth, P.A.5
  • 29
    • 0030961803 scopus 로고    scopus 로고
    • Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution
    • Li M, Liu X, Robinson G et al (1997) Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proc Natl Acad Sci USA 94:3425-3430
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3425-3430
    • Li, M.1    Liu, X.2    Robinson, G.3
  • 30
    • 0020639481 scopus 로고
    • A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas
    • Rosenberg L, Brown RA, Duguid WP (1983) A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas. J Surg Res 35:63-72
    • (1983) J Surg Res , vol.35 , pp. 63-72
    • Rosenberg, L.1    Brown, R.A.2    Duguid, W.P.3
  • 31
    • 0028062752 scopus 로고
    • Beta-cell proliferation in normal and streptozotocin-treated newborn rats: Site, dynamics and capacity
    • Wang RN, Bouwens L, Kloppel G (1994) Beta-cell proliferation in normal and streptozotocin-treated newborn rats: site, dynamics and capacity. Diabetologia 37:1088-1096
    • (1994) Diabetologia , vol.37 , pp. 1088-1096
    • Wang, R.N.1    Bouwens, L.2    Kloppel, G.3
  • 32
    • 0036266272 scopus 로고    scopus 로고
    • Beta-cell neogenesis during prolonged hyperglycemia in rats
    • Lipsett M, Finegood DT (2002) Beta-cell neogenesis during prolonged hyperglycemia in rats. Diabetes 51:1834-1841
    • (2002) Diabetes , vol.51 , pp. 1834-1841
    • Lipsett, M.1    Finegood, D.T.2
  • 33
    • 0031841517 scopus 로고    scopus 로고
    • Extra-insular beta cells associated with ductules are frequent in adult human pancreas
    • Bouwens L, Pipeleers DG (1998) Extra-insular beta cells associated with ductules are frequent in adult human pancreas. Diabetologia 41:629-633
    • (1998) Diabetologia , vol.41 , pp. 629-633
    • Bouwens, L.1    Pipeleers, D.G.2
  • 34
    • 0035008598 scopus 로고    scopus 로고
    • Adaptation of beta-cell mass to substrate oversupply: Enhanced function with normal gene expression
    • Steil GM, Trivedi N, Jonas JC et al (2001) Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression. Am J Physiol Endocrinol Metab 280:E788-E796
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Steil, G.M.1    Trivedi, N.2    Jonas, J.C.3
  • 35
    • 0030903840 scopus 로고    scopus 로고
    • Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat
    • Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S (1997) Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138:1736-1741
    • (1997) Endocrinology , vol.138 , pp. 1736-1741
    • Scaglia, L.1    Cahill, C.J.2    Finegood, D.T.3    Bonner-Weir, S.4
  • 36
    • 0028987251 scopus 로고
    • Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model
    • Finegood DT, Scaglia L, Bonner-Weir S (1995) Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 44:249-256
    • (1995) Diabetes , vol.44 , pp. 249-256
    • Finegood, D.T.1    Scaglia, L.2    Bonner-Weir, S.3
  • 37
    • 0038522555 scopus 로고    scopus 로고
    • Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats
    • Paris M, Bernard-Kargar C, Berthault MF, Bouwens L, Ktorza A (2003) Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats. Endocrinology 144:2717-2727
    • (2003) Endocrinology , vol.144 , pp. 2717-2727
    • Paris, M.1    Bernard-Kargar, C.2    Berthault, M.F.3    Bouwens, L.4    Ktorza, A.5
  • 38
    • 25844442369 scopus 로고    scopus 로고
    • INGAP-related pentadecapeptide: Its modulatory effect upon insulin secretion
    • Borelli MI, Stoppiglia LF, Rezende LF et al (2005) INGAP-related pentadecapeptide: its modulatory effect upon insulin secretion. Regul Pept 131:97-102
    • (2005) Regul Pept , vol.131 , pp. 97-102
    • Borelli, M.I.1    Stoppiglia, L.F.2    Rezende, L.F.3
  • 39
    • 0028331909 scopus 로고
    • Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein
    • Watanabe T, Yonemura Y, Yonekura H et al (1994) Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein. Proc Natl Acad Sci USA 91:3589-3592
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3589-3592
    • Watanabe, T.1    Yonemura, Y.2    Yonekura, H.3
  • 40
    • 0031792577 scopus 로고    scopus 로고
    • Amelioration of diabetes in nonobese diabetic mice with advanced disease by linomide-induced immunoregulation combined with Reg protein treatment
    • Gross DJ, Weiss L, Reibstein I et al (1998) Amelioration of diabetes in nonobese diabetic mice with advanced disease by linomide-induced immunoregulation combined with Reg protein treatment. Endocrinology 139:2369-2374
    • (1998) Endocrinology , vol.139 , pp. 2369-2374
    • Gross, D.J.1    Weiss, L.2    Reibstein, I.3
  • 41
    • 0036894357 scopus 로고    scopus 로고
    • Production and characterization of Reg knockout mice: Reduced proliferation of pancreatic beta-cells in Reg knockout mice
    • Unno M, Nata K, Noguchi N et al (2002) Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice. Diabetes 51(Suppl 3):S478-S483
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3
    • Unno, M.1    Nata, K.2    Noguchi, N.3
  • 42
    • 0033286202 scopus 로고    scopus 로고
    • The Reg gene family and Reg proteins: With special attention to the regeneration of pancreatic beta-cells
    • Okamoto H (1999) The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells. J Hepatobiliary Pancreat Surg 6:254-262
    • (1999) J Hepatobiliary Pancreat Surg , vol.6 , pp. 254-262
    • Okamoto, H.1
  • 43
    • 3242747335 scopus 로고    scopus 로고
    • Control of expression of the lectin-like protein Reg-1 by gastrin: Role of the Rho family GTPase RhoA and a C-rich promoter element
    • Ashcroft FJ, Varro A, Dimaline R, Dockray GJ (2004) Control of expression of the lectin-like protein Reg-1 by gastrin: role of the Rho family GTPase RhoA and a C-rich promoter element. Biochem J 381:397-403
    • (2004) Biochem J , vol.381 , pp. 397-403
    • Ashcroft, F.J.1    Varro, A.2    Dimaline, R.3    Dockray, G.J.4
  • 44
    • 31444432880 scopus 로고    scopus 로고
    • Increased vulnerability of newly forming beta cells to cytokine-induced cell death
    • Meier JJ, Ritzel RA, Maedler K, Gurlo T, Butler PC (2006) Increased vulnerability of newly forming beta cells to cytokine-induced cell death. Diabetologia 49:83-89
    • (2006) Diabetologia , vol.49 , pp. 83-89
    • Meier, J.J.1    Ritzel, R.A.2    Maedler, K.3    Gurlo, T.4    Butler, P.C.5
  • 45
    • 33750927777 scopus 로고    scopus 로고
    • Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein (INGAP) expression
    • (in press)
    • Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L (2006) Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein (INGAP) expression. J Endocrinol (in press)
    • (2006) J Endocrinol
    • Petropavlovskaia, M.1    Makhlin, J.2    Sampalis, J.3    Rosenberg, L.4
  • 46
    • 34548361966 scopus 로고    scopus 로고
    • The role of islet neogenesis-associated protein (INGAP) in islet neogenesis
    • (in press)
    • Lipsett M, Hanley S, Castellarin M et al (2006) The role of islet neogenesis-associated protein (INGAP) in islet neogenesis. Cell Biochem Biophys (in press)
    • (2006) Cell Biochem Biophys
    • Lipsett, M.1    Hanley, S.2    Castellarin, M.3
  • 47
    • 0027449197 scopus 로고
    • A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development
    • Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE (1993) A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 42:1715-1720
    • (1993) Diabetes , vol.42 , pp. 1715-1720
    • Bonner-Weir, S.1    Baxter, L.A.2    Schuppin, G.T.3    Smith, F.E.4
  • 48
    • 18744394636 scopus 로고    scopus 로고
    • Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats
    • Wang GS, Rosenberg L, Scott FW (2005) Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats. Lab Invest 85:675-688
    • (2005) Lab Invest , vol.85 , pp. 675-688
    • Wang, G.S.1    Rosenberg, L.2    Scott, F.W.3
  • 49
    • 0027276885 scopus 로고
    • Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
    • Gu D, Sarvetnick N (1993) Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice. Development 118:33-46
    • (1993) Development , vol.118 , pp. 33-46
    • Gu, D.1    Sarvetnick, N.2
  • 50
    • 27744603796 scopus 로고    scopus 로고
    • Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: Indirect evidence for islet regeneration?
    • Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC (2005) Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia 48:2221-2228
    • (2005) Diabetologia , vol.48 , pp. 2221-2228
    • Meier, J.J.1    Bhushan, A.2    Butler, A.E.3    Rizza, R.A.4    Butler, P.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.