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Volumn 9, Issue 6, 2010, Pages 2909-2919

Metabolomic patterns in glioblastoma and changes during radiotherapy: A clinical microdialysis study

Author keywords

chemometrics; gas chromatography mass spectrometry; glioblastoma; metabolomics; predictive metabolomics; radiotherapy; treatment response

Indexed keywords

ABDOMEN; ARTICLE; BRAIN; CANCER RADIOTHERAPY; CATHETER; GAS CHROMATOGRAPHY; GLIOBLASTOMA; HUMAN; METABOLITE; MICRODIALYSIS; PRIORITY JOURNAL; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 77954611048     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr901088r     Document Type: Article
Times cited : (79)

References (49)
  • 1
    • 47949089526 scopus 로고    scopus 로고
    • Practical approaches to proteomic biomarkers within prostate cancer radiotherapy trials
    • Christensen, E.; Evans, K. R.; Menard, C.; Pintilie, M.; Bristow, R. G. Practical approaches to proteomic biomarkers within prostate cancer radiotherapy trials. Cancer Metastasis Rev. 2008, 27 (3), 375-385
    • (2008) Cancer Metastasis Rev. , vol.27 , Issue.3 , pp. 375-385
    • Christensen, E.1    Evans, K.R.2    Menard, C.3    Pintilie, M.4    Bristow, R.G.5
  • 2
    • 33745061390 scopus 로고    scopus 로고
    • Protein expression in experimental malignant glioma varies over time and is altered by radiotherapy treatment
    • Wibom, C.; Pettersson, F.; Sjostrom, M.; Henriksson, R.; Johansson, M.; Bergenheim, A. T. Protein expression in experimental malignant glioma varies over time and is altered by radiotherapy treatment. Br. J. Cancer 2006, 94 (12), 1853-1863
    • (2006) Br. J. Cancer , vol.94 , Issue.12 , pp. 1853-1863
    • Wibom, C.1    Pettersson, F.2    Sjostrom, M.3    Henriksson, R.4    Johansson, M.5    Bergenheim, A.T.6
  • 3
    • 33846027509 scopus 로고    scopus 로고
    • The clinical value of proton magnetic resonance spectroscopy in adult brain tumours
    • Sibtain, N. A.; Howe, F. A.; Saunders, D. E. The clinical value of proton magnetic resonance spectroscopy in adult brain tumours. Clin. Radiol. 2007, 62 (2), 109-119
    • (2007) Clin. Radiol. , vol.62 , Issue.2 , pp. 109-119
    • Sibtain, N.A.1    Howe, F.A.2    Saunders, D.E.3
  • 4
    • 0028060589 scopus 로고
    • Proton magnetic resonance spectroscopy of brain tumors: An in vitro study
    • discussion 613-614
    • Kinoshita, Y.; Kajiwara, H.; Yokota, A.; Koga, Y. Proton magnetic resonance spectroscopy of brain tumors: an in vitro study. Neurosurgery 1994, 35 (4), 606-13, and discussion 613-614
    • (1994) Neurosurgery , vol.35 , Issue.4 , pp. 606-13
    • Kinoshita, Y.1    Kajiwara, H.2    Yokota, A.3    Koga, Y.4
  • 5
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: Current analytical technologies
    • Dunn, W. B.; Bailey, N. J.; Johnson, H. E. Measuring the metabolome: current analytical technologies. Analyst 2005, 130 (5), 606-625
    • (2005) Analyst , vol.130 , Issue.5 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.2    Johnson, H.E.3
  • 6
    • 24644481093 scopus 로고    scopus 로고
    • High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses
    • Jonsson, P.; Johansson, A. I.; Gullberg, J.; Trygg, J.; A, J.; Grung, B.; Marklund, S.; Sjostrom, M.; Antti, H.; Moritz, T. High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses. Anal. Chem. 2005, 77 (17), 5635-5642
    • (2005) Anal. Chem. , vol.77 , Issue.17 , pp. 5635-5642
    • Jonsson, P.1    Johansson, A.I.2    Gullberg, J.3    Trygg, J.4    A, J.5    Grung, B.6    Marklund, S.7    Sjostrom, M.8    Antti, H.9    Moritz, T.10
  • 8
    • 0019855502 scopus 로고
    • Classification of human cancer cells by means of capillary gas chromatography and pattern recognition analysis
    • Jellum, E.; Bjornson, I.; Nesbakken, R.; Johansson, E.; Wold, S. Classification of human cancer cells by means of capillary gas chromatography and pattern recognition analysis. J. Chromatogr. 1981, 217, 231-237
    • (1981) J. Chromatogr. , vol.217 , pp. 231-237
    • Jellum, E.1    Bjornson, I.2    Nesbakken, R.3    Johansson, E.4    Wold, S.5
  • 9
    • 50649113948 scopus 로고    scopus 로고
    • Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy
    • Tabatabaei, P.; Bergstrom, P.; Henriksson, R.; Bergenheim, A. T. Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy. J. Neurooncol. 2008, 90 (1), 35-39
    • (2008) J. Neurooncol. , vol.90 , Issue.1 , pp. 35-39
    • Tabatabaei, P.1    Bergstrom, P.2    Henriksson, R.3    Bergenheim, A.T.4
  • 11
    • 0344642991 scopus 로고    scopus 로고
    • Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis
    • Roslin, M.; Henriksson, R.; Bergstrom, P.; Ungerstedt, U.; Bergenheim, A. T. Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis. J. Neurooncol. 2003, 61 (2), 151-160
    • (2003) J. Neurooncol. , vol.61 , Issue.2 , pp. 151-160
    • Roslin, M.1    Henriksson, R.2    Bergstrom, P.3    Ungerstedt, U.4    Bergenheim, A.T.5
  • 12
    • 20044385570 scopus 로고    scopus 로고
    • A microdialysis technique for routine measurement of macromolecules in the injured human brain
    • and discussion 1268-1270
    • Hillman, J.; Aneman, O.; Anderson, C.; Sjogren, F.; Saberg, C.; Mellergard, P. A microdialysis technique for routine measurement of macromolecules in the injured human brain. Neurosurgery 2005, 56 (6), 1264-8, and discussion 1268-1270
    • (2005) Neurosurgery , vol.56 , Issue.6 , pp. 1264-1268
    • Hillman, J.1    Aneman, O.2    Anderson, C.3    Sjogren, F.4    Saberg, C.5    Mellergard, P.6
  • 13
    • 67049117519 scopus 로고    scopus 로고
    • Predictive metabolomics evaluation of nutrition-modulated metabolic stress responses in human blood serum during the early recovery phase of strenuous physical exercise
    • Chorell, E.; Moritz, T.; Branth, S.; Antti, H.; Svensson, M. B. Predictive metabolomics evaluation of nutrition-modulated metabolic stress responses in human blood serum during the early recovery phase of strenuous physical exercise. J. Proteome Res. 2009, 8 (6), 2966-2977
    • (2009) J. Proteome Res. , vol.8 , Issue.6 , pp. 2966-2977
    • Chorell, E.1    Moritz, T.2    Branth, S.3    Antti, H.4    Svensson, M.B.5
  • 15
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structures (OPLS)
    • Trygg, J.; Wold, S. Orthogonal projections to latent structures (OPLS). J. Chemom. 2002, 16 (3), 119-128
    • (2002) J. Chemom. , vol.16 , Issue.3 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 16
    • 0000629975 scopus 로고
    • Cross-Validatory Choice and Assessment of Statistical Predictions
    • Stone, M. Cross-Validatory Choice and Assessment of Statistical Predictions. J. R. Stat. Soc., Ser. B (Methodological) 1974, 36 (2), 111-147
    • (1974) J. R. Stat. Soc. Ser. B (Methodological) , vol.36 , Issue.2 , pp. 111-147
    • Stone, M.1
  • 18
  • 23
    • 33847370301 scopus 로고    scopus 로고
    • Tumour metabolomics in animal models of human cancer
    • Griffin, J. L.; Kauppinen, R. A. Tumour metabolomics in animal models of human cancer. J. Proteome Res. 2007, 6 (2), 498-505.
    • (2007) J. Proteome Res. , vol.6 , Issue.2 , pp. 498-505
    • Griffin, J.L.1    Kauppinen, R.A.2
  • 25
    • 0033909858 scopus 로고    scopus 로고
    • Extracellular glutamate and other metabolites in and around RG2 rat glioma: An intracerebral microdialysis study
    • Behrens, P. F.; Langemann, H.; Strohschein, R.; Draeger, J.; Hennig, J. Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study. J Neurooncol. 2000, 47 (1), 11-22.
    • (2000) J Neurooncol. , vol.47 , Issue.1 , pp. 11-22
    • Behrens, P.F.1    Langemann, H.2    Strohschein, R.3    Draeger, J.4    Hennig, J.5
  • 26
    • 0029367916 scopus 로고
    • Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours
    • Florian, C. L.; Preece, N. E.; Bhakoo, K. K.; Williams, S. R.; Noble, M. Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours. NMR Biomed. 1995, 8 (6), 253-264
    • (1995) NMR Biomed. , vol.8 , Issue.6 , pp. 253-264
    • Florian, C.L.1    Preece, N.E.2    Bhakoo, K.K.3    Williams, S.R.4    Noble, M.5
  • 28
    • 6344261877 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism
    • McKnight, T. R. Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism. Semin. Oncol. 2004, 31 (5), 605-617
    • (2004) Semin. Oncol. , vol.31 , Issue.5 , pp. 605-617
    • McKnight, T.R.1
  • 29
    • 0033198997 scopus 로고    scopus 로고
    • Glioma cells release excitotoxic concentrations of glutamate
    • Ye, Z. C.; Sontheimer, H. Glioma cells release excitotoxic concentrations of glutamate. Cancer Res. 1999, 59 (17), 4383-4391
    • (1999) Cancer Res. , vol.59 , Issue.17 , pp. 4383-4391
    • Ye, Z.C.1    Sontheimer, H.2
  • 30
    • 35148854098 scopus 로고    scopus 로고
    • Autocrine glutamate signaling promotes glioma cell invasion
    • Lyons, S. A.; Chung, W. J.; Weaver, A. K.; Ogunrinu, T.; Sontheimer, H. Autocrine glutamate signaling promotes glioma cell invasion. Cancer Res. 2007, 67 (19), 9463-9471
    • (2007) Cancer Res. , vol.67 , Issue.19 , pp. 9463-9471
    • Lyons, S.A.1    Chung, W.J.2    Weaver, A.K.3    Ogunrinu, T.4    Sontheimer, H.5
  • 31
    • 41749114501 scopus 로고    scopus 로고
    • A role for glutamate in growth and invasion of primary brain tumors
    • Sontheimer, H. A role for glutamate in growth and invasion of primary brain tumors. J. Neurochem. 2008, 105 (2), 287-295
    • (2008) J. Neurochem. , vol.105 , Issue.2 , pp. 287-295
    • Sontheimer, H.1
  • 32
    • 0034800265 scopus 로고    scopus 로고
    • Glutamate release promotes growth of malignant gliomas
    • Takano, T.; Lin, J. H.; Arcuino, G.; Gao, Q.; Yang, J.; Nedergaard, M. Glutamate release promotes growth of malignant gliomas. Nat. Med. 2001, 7 (9), 1010-1015
    • (2001) Nat. Med. , vol.7 , Issue.9 , pp. 1010-1015
    • Takano, T.1    Lin, J.H.2    Arcuino, G.3    Gao, Q.4    Yang, J.5    Nedergaard, M.6
  • 33
    • 33751243646 scopus 로고    scopus 로고
    • Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2,4 diaminobutyric acid (DAB)
    • Bergenheim, A. T.; Roslin, M.; Ungerstedt, U.; Waldenstrom, A.; Henriksson, R.; Ronquist, G. Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2,4 diaminobutyric acid (DAB). J. Neurooncol. 2006, 80 (3), 285-293
    • (2006) J. Neurooncol. , vol.80 , Issue.3 , pp. 285-293
    • Bergenheim, A.T.1    Roslin, M.2    Ungerstedt, U.3    Waldenstrom, A.4    Henriksson, R.5    Ronquist, G.6
  • 34
    • 0035808579 scopus 로고    scopus 로고
    • Effect of extracellular long-time microperfusion of high concentrations of glutamate and glycine on picrotoxin seizure thresholds in the hippocampus of freely moving rats
    • Sierra-Paredes, G.; Senra-Vidal, A.; Sierra-Marcuno, G. Effect of extracellular long-time microperfusion of high concentrations of glutamate and glycine on picrotoxin seizure thresholds in the hippocampus of freely moving rats. Brain Res. 2001, 888 (1), 19-25.
    • (2001) Brain Res. , vol.888 , Issue.1 , pp. 19-25
    • Sierra-Paredes, G.1    Senra-Vidal, A.2    Sierra-Marcuno, G.3
  • 35
    • 0030741163 scopus 로고    scopus 로고
    • Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy
    • Kinoshita, Y.; Yokota, A. Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy. NMR Biomed. 1997, 10 (1), 2-12.
    • (1997) NMR Biomed. , vol.10 , Issue.1 , pp. 2-12
    • Kinoshita, Y.1    Yokota, A.2
  • 36
    • 12544249525 scopus 로고    scopus 로고
    • Translational neurochemical research in acute human brain injury: The current status and potential future for cerebral microdialysis
    • Hillered, L.; Vespa, P. M.; Hovda, D. A. Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis. J. Neurotrauma 2005, 22 (1), 3-41.
    • (2005) J. Neurotrauma , vol.22 , Issue.1 , pp. 3-41
    • Hillered, L.1    Vespa, P.M.2    Hovda, D.A.3
  • 37
    • 60349088264 scopus 로고    scopus 로고
    • Intracerebral monitoring in comatose patients treated with hypothermia after a cardiac arrest
    • Nordmark, J.; Rubertsson, S.; Mortberg, E.; Nilsson, P.; Enblad, P. Intracerebral monitoring in comatose patients treated with hypothermia after a cardiac arrest. Acta Anaesthesiol. Scand. 2009, 53 (3), 289-298
    • (2009) Acta Anaesthesiol. Scand. , vol.53 , Issue.3 , pp. 289-298
    • Nordmark, J.1    Rubertsson, S.2    Mortberg, E.3    Nilsson, P.4    Enblad, P.5
  • 38
    • 0038681998 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy ((1)H MRS) of human brain tumours: Assessment of differences between tumour types and its applicability in brain tumour categorization
    • Majos, C.; Alonso, J.; Aguilera, C.; Serrallonga, M.; Perez-Martin, J.; Acebes, J. J.; Arus, C.; Gili, J. Proton magnetic resonance spectroscopy ((1)H MRS) of human brain tumours: assessment of differences between tumour types and its applicability in brain tumour categorization. Eur. Radiol. 2003, 13 (3), 582-591
    • (2003) Eur. Radiol. , vol.13 , Issue.3 , pp. 582-591
    • Majos, C.1    Alonso, J.2    Aguilera, C.3    Serrallonga, M.4    Perez-Martin, J.5    Acebes, J.J.6    Arus, C.7    Gili, J.8
  • 40
    • 0029906468 scopus 로고    scopus 로고
    • Glioma invasion in vitro: Regulation by matrix metalloprotease-2 and protein kinase C
    • Uhm, J. H.; Dooley, N. P.; Villemure, J. G.; Yong, V. W. Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C. Clin. Exp. Metastasis 1996, 14 (5), 421-433
    • (1996) Clin. Exp. Metastasis , vol.14 , Issue.5 , pp. 421-433
    • Uhm, J.H.1    Dooley, N.P.2    Villemure, J.G.3    Yong, V.W.4
  • 42
    • 35848947240 scopus 로고    scopus 로고
    • Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells
    • Karmakar, S.; Banik, N. L.; Ray, S. K. Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells. Neurochem. Res. 2007, 32 (12), 2094-2102
    • (2007) Neurochem. Res. , vol.32 , Issue.12 , pp. 2094-2102
    • Karmakar, S.1    Banik, N.L.2    Ray, S.K.3
  • 43
    • 0031977852 scopus 로고    scopus 로고
    • Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain
    • Hillered, L.; Valtysson, J.; Enblad, P.; Persson, L. Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain. J. Neurol. Neurosurg. Psychiatry 1998, 64 (4), 486-491
    • (1998) J. Neurol. Neurosurg. Psychiatry , vol.64 , Issue.4 , pp. 486-491
    • Hillered, L.1    Valtysson, J.2    Enblad, P.3    Persson, L.4
  • 44
    • 0028986939 scopus 로고
    • In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation
    • Mahmood, U.; Alfieri, A. A.; Ballon, D.; Traganos, F.; Koutcher, J. A. In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation. Cancer Res. 1995, 55 (6), 1248-1254
    • (1995) Cancer Res. , vol.55 , Issue.6 , pp. 1248-1254
    • Mahmood, U.1    Alfieri, A.A.2    Ballon, D.3    Traganos, F.4    Koutcher, J.A.5
  • 45
    • 0019226227 scopus 로고
    • Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli
    • Foote, R. S.; Mitra, S.; Pal, B. C. Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli. Biochem. Biophys. Res. Commun. 1980, 97 (2), 654-659
    • (1980) Biochem. Biophys. Res. Commun. , vol.97 , Issue.2 , pp. 654-659
    • Foote, R.S.1    Mitra, S.2    Pal, B.C.3


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