Do alterations in mitochondrial DNA play a role in breast carcinogenesis?

Journal of Oncology

Volumn , Issue , 2010, Pages

  Rohan, Thomas E ^a   Wong, Lee Jun ^b   Wang, Tao ^a   Haines, Jonathan ^c   Kabat, Geoffrey C ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

BREAST CARCINOGENESIS; CANCER CELL; CANCER RISK; DNA POLYMORPHISM; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; REVIEW;

EID: 77954600212     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2010/604304     Document Type: Review

References (119)

1. Lichtenstein P., Holm N. V., Verkasalo P. K., Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark, and Finland The New England Journal of Medicine 2000 343 2 78 85
2. Beral V., Bull D., Doll R., Peto R., Reeves G., Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58 209 women with breast cancer and 101 986 women without the disease The Lancet 2001 358 9291 1389 1399
3. Thompson D., Easton D., The genetic epidemiology of breast cancer genes Journal of Mammary Gland Biology and Neoplasia 2004 9 3 221 236
4. Hartmann L. C., Sellers T. A., Frost M. H., Benign breast disease and the risk of breast cancer The New England Journal of Medicine 2005 353 3 229 237
5. Schnitt S. J., Benign breast disease and breast cancer risk: morphology and beyond American Journal of Surgical Pathology 2003 27 6 836 841
6. Adami H., Hunter D., Trichopoulous D., Textbook of Cancer Epidemiology 2002 New York, NY, USA Oxford University Press
7. Kelsey J. L., Gammon M. D., John E. M., Reproductive factors and breast cancer Epidemiologic Reviews 1993 15 1 36 47
8. Russo J., Moral R., Balogh G. A., Mailo D., Russo I. H., The protective role of pregnancy in breast cancer Breast Cancer Research 2005 7 3 131 142
9. Beral V., Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer The Lancet 1997 350 9084 1047 1059
10. Rossouw J. E., Anderson G. L., Prentice R. L., Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial Journal of the American Medical Association 2002 288 3 321 333
11. Linos E., Holmes M. D., Willett W. C., Diet and breast cancer Current Oncology Reports 2007 9 1 31 41
12. Hamajima N., Hirose K., Tajima K., Alcohol, tobacco and breast cancercollaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease British Journal of Cancer 2002 87 11 1234 1245
13. Reynolds P., Hurley S., Goldberg D. E., Active smoking household passive smoking, and breast cancer: evidence from the California Teachers Study Journal of the National Cancer Institute 2004 96 1 29 37 (Pubitemid 38180957)
14. Monninkhof E. M., Elias S. G., Vlems F. A., Physical activity and breast cancer: a systematic review Epidemiology 2007 18 1 137 157
15. World Cancer Research Fund/American Institute for Cancer Research, Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective 2007 Washington, DC, USA AICR
16. Duncan A. M., The role of nutrition in the prevention of breast cancer AACN Clinical Issues 2004 15 1 119 135
17. Van Gils C. H., Peeters P. H. M., Bueno-de-Mesquita H. B., Consumption of vegetables and fruits and risk of breast cancer Journal of the American Medical Association 2005 293 2 183 193
18. Ambrosone C. B., Oxidants and antioxidants in breast cancer Antioxidants and Redox Signaling 2000 2 4 903 917
19. Halliwell B., Oxidative stress and cancer: have we moved forward? Biochemical Journal 2007 401 1 1 11
20. Kang D. H., Oxidative stress, DNA damage, and breast cancer AACN Clinical Issues 2002 13 4 540 549
21. Marnett L. J., Oxyradicals and DNA damage Carcinogenesis 2000 21 3 361 370
22. Klaunig J. E., Kamendulis L. M., The role of oxidative stress in carcinogenesis Annual Review of Pharmacology and Toxicology 2004 44 239 267
23. Goodman M., Bostick R. M., Dash C., Flanders W. D., Mandel J. S., Hypothesis: oxidative stress score as a combined measure of pro-oxidant and antioxidant exposures Annals of Epidemiology 2007 17 5 394 399
24. Canter J. A., Kallianpur A. R., Parl F. F., Millikan R. C., Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women Cancer Research 2005 65 17 8028 8033
25. Jakupciak J. P., Wang W., Markowitz M. E., Mitochondrial DNA as a cancer biomarker Journal of Molecular Diagnostics 2005 7 2 258 267
26. Fliss M. S., Usadel H., Caballero O. L., Facile detection of mitochondrial DNA mutations in tumors and bodily fluids Science 2000 287 5460 2017 2019
27. Frezza C., Gottlieb E., Mitochondria in cancer: not just innocent bystanders Seminars in Cancer Biology 2009 19 1 4 11
28. Hood D. A., Adhihetty P. J., Colavecchia M., Mitochondrial biogenesis and the role of the protein import pathway Medicine and Science in Sports and Exercise 2003 35 1 86 94
29. Jackson M. J., Papa S., Bolanos J., Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function Molecular Aspects of Medicine 2002 23 13 209 285
30. Petros J. A., Baumann A. K., Ruiz-Pesini E., mtDNA mutations increase tumorigenicity in prostate cancer Proceedings of the National Academy of Sciences of the United States of America 2005 102 3 719 724
31. Yager J. D., Liehr J. G., Molecular mechanisms of estrogen carcinogenesis Annual Review of Pharmacology and Toxicology 1996 36 203 232
32. Wright R. M., McManaman J. L., Repine J. E., Alcohol-induced breast cancer: a proposed mechanism Free Radical Biology and Medicine 1999 26 3-4 348 354
33. Brandon M., Baldi P., Wallace D. C., Mitochondrial mutations in cancer Oncogene 2006 25 34 4647 4662
34. Carew J. S., Huang P., Mitochondrial defects in cancer Molecular Cancer 2002 1, article 9
35. Klaunig J. E., Kamendulis L. M., Hocevar B. A., Oxidative stress and oxidative damage in carcinogenesis Toxicologic Pathology 2010 38 1 96 109
36. Covarrubias D., Bai R.-K., Wong L.-J. C., Leal S. M., Mitochondrial DNA variant interactions modify breast cancer risk Journal of Human Genetics 2008 53 10 924 928
37. DiMauro S., Schon E. A., Mitochondrial respiratory-chain diseases The New England Journal of Medicine 2003 348 26 2656 2668
38. Taanman J.-W., The mitochondrial genome: structure, transcription, translation and replication Biochimica et Biophysica Acta 1999 1410 2 103 123
39. Jeong S.-Y., Seol D.-W., The role of mitochondria in apoptosis Journal of Biochemistry and Molecular Biology 2008 41 1 11 22
40. Henze K., Martin W., Evolutionary biology: essence of mitochondria Nature 2003 426 6963 127 128
41. Freitas R. Jr., Basic Capabilities 1999 Austin, Tex, USA Landes Bioscience
42. Vander A., Sherman J., Luciano D., Human Physiology: The Mechanisms of Body Function 1990 5th New York, NY, USA McGraw-Hill
43. Becker W., Deamer D., The World of the Cell 1991 2nd Redwood City, Calif, USA Benjamin/Cummings
44. Betteridge D. J., What is oxidative stress? Metabolism 2000 49 2, supplement 1 3 8
45. Karihtala P., Soini Y., Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies APMIS 2007 115 2 81 103
46. Chatterjee A., Mambo E., Sidransky D., Mitochondrial DNA mutations in human cancer Oncogene 2006 25 34 4663 4674
47. Bae Y. S., Kang S. W., Seo M. S., Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation Journal of Biological Chemistry 1997 272 1 217 221
48. Leslie N. R., The redox regulation of PI 3-kinase-dependent signaling Antioxidants and Redox Signaling 2006 8 9-10 1765 1774
49. Basu S., F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications Antioxidants and Redox Signaling 2008 10 8 1405 1434
50. Nemoto S., Finkel T., Ageing and the mystery at Arles Nature 2004 429 6988 149 152
51. Chen J. Q., Brown T. R., Yager J. D., Mechanisms of hormone carcinogenesis: evolution of views, role of mitochondria Advances in Experimental Medicine and Biology 2008 630 1 18
52. Chance B., Sies H., Boveris A., Hydroperoxide metabolism in mammalian organs Physiological Reviews 1979 59 3 527 605
53. Kumaraguruparan R., Kabalimoorthy J., Nagini S., Correlation of tissue lipid peroxidation and antioxidants with clinical stage and menopausal status in patients with adenocarcinoma of the breast Clinical Biochemistry 2005 38 2 154 158
54. Malins D. C., Haimanot R., Major alterations in the nucleotide structure of DNA in cancer of the female breast Cancer Research 1991 51 19 5430 5432
55. Malins D. C., Holmes E. H., Polissar N. L., Gunselman S. J., The etiology of breast cancer: characteristic alterations in hydroxyl radical-induced DNA base lesions during oncogenesis with potential for evaluating incidence risk Cancer 1993 71 10 3036 3043
56. Musarrat J., Arezina-Wilson J., Wani A. A., Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis European Journal of Cancer 1996 32 7 1209 1214
57. Tas F., Hansel H., Belce A., Oxidative stress in breast cancer Medical Oncology 2005 22 1 11 15
58. Li D., Zhang W., Zhu J., Oxidative DNA damage and 8-hydroxy-2- deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer Molecular Carcinogenesis 2001 31 4 214 223
59. Wang M., Dhingra K., Hittelman W. N., Liehr J. G., De Andrade M., Li D., Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues Cancer Epidemiology Biomarkers and Prevention 1996 5 9 705 710
60. Gnen A., Erten D., Aslan S., Akinci M., imek B., Torun M., Lipid peroxidation and antioxidant status in blood and tissue of malignant breast tumor and benign breast disease Cell Biology International 2006 30 4 376 380
61. Punnonen K., Ahotupa M., Asaishi K., Hyoty M., Kudo R., Punnonen R., Antioxidant enzyme activities and oxidative stress in human breast cancer Journal of Cancer Research and Clinical Oncology 1994 120 6 374 377
62. Djuric Z., Heilbrun L. K., Simon M. S., Levels of 5-hydroxymethyl- 2′ -deoxyuridine in DNA from blood as a marker of breast cancer Cancer 1996 77 4 691 696
63. Gnen A., zkan Y., Torun M., imek B., Plasma malondialdehyde (MDA) levels in breast and lung cancer patients Journal of Clinical Pharmacy and Therapeutics 2001 26 2 141 144
64. Huang Y.-L., Sheu J.-Y., Lin T.-H., Association between oxidative stress and changes of trace elements in patients with breast cancer Clinical Biochemistry 1999 32 2 131 136
65. Khanzode S. S., Muddeshwar M. G., Khanzode S. D., Dakhale G. N., Antioxidant enzymes and lipid peroxidation in different stages of breast cancer Free Radical Research 2004 38 1 81 85
66. Kumaraguruparan R., Subapriya R., Kabalimoorthy J., Nagini S., Antioxidant profile in the circulation of patients with fibroadenoma and adenocarcinoma of the breast Clinical Biochemistry 2002 35 4 275 279 (Pubitemid 34804896)
67. Ray G., Batra S., Shukla N. K., Lipid peroxidation, free radical production and antioxidant status in breast cancer Breast Cancer Research and Treatment 2000 59 2 163 170
68. ener D. E., Gnen A., Akinci M., Torun M., Lipid peroxidation and total antioxidant status in patients with breast cancer Cell Biochemistry and Function 2007 25 4 377 382
69. Yeh C.-C., Hou M.-F., Tsai S.-M., Superoxide anion radical, lipid peroxides and antioxidant status in the blood of patients with breast cancer Clinica Chimica Acta 2005 361 1-2 104 111
70. Rossner P. Jr., Gammon M. D., Terry M. B., Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk Cancer Epidemiology Biomarkers and Prevention 2006 15 4 639 644
71. Alagol H., Erdem E., Sancak B., Turkmen G., Camlibel M., Bugdayci G., Nitric oxide biosynthesis and malondialdehyde levels in advanced breast cancer Australian and New Zealand Journal of Surgery 1999 69 9 647 650
72. Gerber M., Richardson S., Crastes de Paulet P., Pujol H., Crastes de Paulet A., Relationship between vitamin E and polyunsaturated fatty acids in breast cancer. Nutritional and metabolic aspects Cancer 1989 64 11 2347 2353
73. Dai Q., Gao Y.-T., Shu X.-O., Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Wmen's Health Study Journal of Clinical Oncology 2009 27 15 2482 2488
74. Martin L. J., Boyd N. F., Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence Breast Cancer Research 2008 10 1 201
75. Boyd N. F., McGuire V., The possible role of lipid peroxidation in breast cancer risk Free Radical Biology and Medicine 1991 10 3-4 185 190
76. Mannello F., Tonti G. A. M., Pagliarani S., The 8-epimer of prostaglandin F2, a marker of lipid peroxidation and oxidative stress, is decreased in the nipple aspirate fluid of women with breast cancer International Journal of Cancer 2007 120 9 1971 1976
77. DiMauro S., Mitochondrial DNA medicine Bioscience Reports 2007 27 13 5 9
78. Cavalli L. R., Liang B. C., Mutagenesis, tumorigenicity, and apoptosis: are the mitochondria involved? Mutation Research 1998 398 1-2 19 26
79. Wallace D. C., A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine Annual Review of Genetics 2005 39 359 407
80. Zamzami N., Kroemer G., The mitochondrion in apoptosis: how Pandora's box opens Nature Reviews Molecular Cell Biology 2001 2 1 67 71
81. Zhu W., Qin W., Bradley P., Wessel A., Puckett C. L., Sauter E. R., Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid Carcinogenesis 2005 26 1 145 152
82. Kulawiec M., Safina A., Desouki M. M., Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion Cancer Biology and Therapy 2008 7 11 1732 1743
83. Bianchi M. S., Bianchi N. O., Bailliet G., Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients Cytogenetics and Cell Genetics 1995 71 1 99 103
84. Parrella P., Xiao Y., Fliss M., Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates Cancer Research 2001 61 20 7623 7626
85. Tan D.-J., Bai R.-K., Wong L.-J. C., Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer Cancer Research 2002 62 4 972 976
86. Tseng L.-M., Yin P.-H., Chi C.-W., Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer Genes Chromosomes and Cancer 2006 45 7 629 638
87. Wang C.-Y., Wang H.-W., Yao Y.-G., Kong Q.-P., Zhang Y.-P., Somatic mutations of mitochondrial genome in early stage breast cancer International Journal of Cancer 2007 121 6 1253 1256
88. Zhu W., Qin W., Sauter E. R., Large-scale mitochondrial DNA deletion mutations and nuclear genome instability in human breast cancer Cancer Detection and Prevention 2004 28 2 119 126
89. Ye C., Shu X. O., Pierce L., Mutations in the mitochondrial DNA D-loop region and breast cancer risk Breast Cancer Research and Treatment 2010 119 2 431 436
90. Dani M. A., Dani S. U., Lima S. P., Less DeltamtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation Genetics and Molecular Research 2004 3 3 395 409
91. Bai R.-K., Leal S. M., Covarrubias D., Liu A., Wong L.-J. C., Mitochondrial genetic background modifies breast cancer risk Cancer Research 2007 67 10 4687 4694
92. Canter J. A., Kallianpur A. R., Parl F. F., Millikan R. C., In response: mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women Cancer Research 2006 66 3 1880 1881
93. Czarnecka A. M., Krawczyk T., Zdrozny M., Mitochondrial NADH-dehydrogenase subunit 3 (ND3) polymorphism (A10398G) and sporadic breast cancer in Poland Breast Cancer Research and Treatment 2010 121 2 511 518
94. Darvishi K., Sharma S., Bhat A. K., Rai E., Bamezai R. N. K., Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer Cancer Letters 2007 249 2 249 255
95. Mosquera-Miguel A., Alvarez-Iglesias V., Carracedo A., Is mitochondrial DNA variation associated with sporadic breast cancer risk? Cancer Research 2008 68 2 623 625
96. Pezzotti A., Kraft P., Hankinson S. E., Hunter D. J., Buring J., Cox D. G., The mitochondrial A10398G polymorphism, interaction with alcohol consumption, and breast cancer risk PLoS One 2009 4 4, article e5356
97. Setiawan V. W., Chu L.-H., John E. M., Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women Cancer Genetics and Cytogenetics 2008 181 1 16 19
98. Ye C., Gao Y.-T., Wen W., Association of mitochondrial DNA displacement loop (CA)n dinucleotide repeat polymorphism with breast cancer risk and survival among Chinese women Cancer Epidemiology Biomarkers and Prevention 2008 17 8 2117 2122
99. Altshuler D., Daly M. J., Lander E. S., Genetic mapping in human disease Science 2008 322 5903 881 888
100. Roy D., Cai Q., Felty Q., Narayan S., Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers Journal of Toxicology and Environmental Health Part B 2007 10 4 235 257
101. Masayesva B. G., Mambo E., Taylor R. J., Mitochondrial DNA content increase in response to cigarette smoking Cancer Epidemiology Biomarkers and Prevention 2006 15 1 19 24
102. Miro O., Alonso J. R., Jarreta D., Casademont J., Urbano-Marquez A., Cardellach F., Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes Carcinogenesis 1999 20 7 1331 1336
103. Smith P. R., Cooper J. M., Govan G. G., Harding A. H. V., Schapira A. H. V., Smoking and mitochondrial function: a model for environmental toxins Quarterly Journal of Medicine 1993 86 10 657 660
104. Tan D., Goerlitz D. S., Dumitrescu R. G., Associations between cigarette smoking and mitochondrial DNA abnormalities in buccal cells Carcinogenesis 2008 29 6 1170 1177
105. Shen J., Platek M., Mahasneh A., Ambrosone C. B., Zhao H., Mitochondrial copy number and risk of breast cancer: a pilot study Mitochondrion 2010 10 1 62 68
106. Platek M. E., Shields P. G., Tan D., Alcohol consumption and breast tumor mitochondrial DNA mutations Breast Cancer Research and Treatment 2010 121 2 453 460
107. Civitarese A. E., Ravussin E., Minireview: mitochondrial energetics and insulin resistance Endocrinology 2008 149 3 950 954
108. Abnet C. C., Huppi K., Carrera A., Control region mutations and common deletion are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma BMC Cancer 2004 4, article 30
109. Lee H.-C., Li S.-H., Lin J.-C., Wu C.-C., Yeh D.-C., Wei Y.-H., Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma Mutation Research 2004 547 1-2 71 78
110. Ma Y., Bai R.-K., Trieu R., Wong L.-J. C., Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids Biochimica et Biophysica Acta 2010 1797 1 29 37
111. Tan D.-J., Chang J., Liu L.-L., Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer BMC Cancer 2006 6, article 93
112. Yin P. H., Lee H. C., Chau G. Y., Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma British Journal of Cancer 2004 90 12 2390 2396
113. Polyak K., Li Y., Zhu H., Somatic mutations of the mitochondrial genome in human colorectal tumours Nature Genetics 1998 20 3 291 293
114. Antoniou A., Pharoah P. D. P., Narod S., Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies American Journal of Human Genetics 2003 72 5 1117 1130
115. Bradbury A. R., Olopade O. I., Genetic susceptibility to breast cancer Reviews in Endocrine and Metabolic Disorders 2007 8 3 255 267
116. Antoniou A. C., Easton D. F., Models of genetic susceptibility to breast cancer Oncogene 2006 25 43 5898 5905
117. Manolio T. A., Brooks L. D., Collins F. S., A HapMap harvest of insights into the genetics of common disease Journal of Clinical Investigation 2008 118 5 1590 1605
118. Shoubridge E. A., Nuclear genetic defects of oxidative phosphorylation Human Molecular Genetics 2001 10 20 2277 2284
119. Koene S., Smeitink J., Mitochondrial medicine: entering the era of treatment Journal of Internal Medicine 2009 265 2 193 209