Protecting motor networks during perinatal ischemia: The case for delta-opioid receptors

Annals of the New York Academy of Sciences

Volumn 1198, Issue , 2010, Pages 260-270

  Johnson, Stephen M ^a   Turner, Sara M F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

ischemia; neuroprotection; opioid; perinatal

Indexed keywords

DELTA OPIATE RECEPTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; NEUROPROTECTIVE AGENT; POTASSIUM; SODIUM;

BLOOD BRAIN BARRIER; BLOOD PLACENTA BARRIER; CONFERENCE PAPER; HUMAN; ISCHEMIA; MOTONEURON; NERVE CELL NETWORK; NEUROPROTECTION; PERINATAL ISCHEMIA; POTASSIUM TRANSPORT; RECEPTOR UPREGULATION; RESPIRATION DEPRESSION; SEIZURE; SODIUM TRANSPORT; BLOOD FLOW VELOCITY; BRAIN CIRCULATION; FEMALE; NERVE CELL; NEWBORN; NEWBORN DISEASE; NEWBORN HYPOXIA; PATHOPHYSIOLOGY; PERINATAL CARE; PHYSIOLOGY; PREGNANCY; PRENATAL DIAGNOSIS; REVIEW; SYNAPSE;

MAMMALIA;

ASPHYXIA NEONATORUM; BLOOD FLOW VELOCITY; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; ISCHEMIA; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTRANSMITTER AGENTS; PERINATAL CARE; POTASSIUM; PREGNANCY; PRENATAL DIAGNOSIS; RECEPTORS, OPIOID, DELTA; SODIUM; SYNAPSES;

EID: 77954574721     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2010.05434.x     Document Type: Conference Paper

References (74)

1. Raju, T.N., K.B. Nelson, D. Ferriero, et al. 2007. NICHD-NINDS perinatal stroke workshop participants: ischemic perinatal stroke: summary of a workshop sponsored by the National Institute of Neurological Disorders and Stroke. Pediatrics 120 : 609 616.
2. Nelson, K.B. 2007. Perinatal ischemic stroke. Stroke 38 : 742 745.
3. Badr, L.K. I. Purdy. 2006. Brain injury in the infant: the old, the new and the uncertain. J. Perinat. Neonat. Nurs. 20 : 163 175.
4. Volpe, J.J. 1994. Brain injury in the premature infant-current concepts. Prev. Med. 23 : 638 645.
5. Whitelaw, A. M. Thoresen. 2002. Clinical trials of treatments after perinatal asphyxia. Curr. Opin. Pediatr. 14 : 664 668.
6. Legido, A., C.D. Katsetos, O.P. Mishra, et al. 2000. Perinatal hypoxic ischemic encephalopathy: current and future treatments. Intl. Ped. 15 : 143 151.
7. Laugesaar, R., A. Kolk, T. Tomberg, et al. 2007. Acutely and retrospectively diagnosed perinatal stroke: a population-based study. Stroke 38 : 2234 2240.
8. Palsdottir, K., A. Dagbjartsson, T. Thorkelsson, et al. 2007. Birth asphyxia and hypoxic ischemic encephalopathy, incidence and obstertric risk. Laeknabladid 93 : 595 601.
9. Volpe, J.J. 2001. Perinatal brain injury: from pathogenesis to neuroprotection. Ment. Retard. Dev. Disabil. Res. Rev. 7 : 56 64.
10. Sotero de Menezes, M., & D.W.W. Shaw. 2006. Hypoxic-ischemic brain injury in the newborn. eMedicine April, 1 39.
11. van Schie, P.E.M., J.G. Becher, A.J. Dallmeijer, et al. 2007. Motor outcome at the age of one after perinatal hypoxic-ischemic encephalopathy. Neuropediatrics 38 : 71 77.
12. Ruggieri, M., A. Smarason M. Pike. 1999. Spinal cord insults in the prenatal, perinatal, and neonatal periods. Dev. Med. & Child Neurol. 41 : 311 317.
13. Barnette, A.R. T.E. Inder. 2009. Evaluation and management of stroke in the neonate. Clin. Perinatol. 36 : 125 136.
14. Robertson, N.J. O. Iwata. 2007. Bench to bedside strategies for optimizing neuroprotection following perinatal hypoxia-ischemia in high and low resource settings. Early Hum. Dev. 83 : 801 811.
15. Sanders, R.D., H.J. Manning, D. Ma, et al. 2007. Perinatal neuroprotection. Curr. Anaesth. Crit. Care 18 : 215 224.
16. Johnston, M.W. 2005. Excitotoxicity in perinatal brain injury. Brain Pathol. 15 : 234 240.
17. Hagberg, H., K. Blomgren C. Mallard. 2001. Neuroprotection of the fetal and neonatal brain. In Fetal and Neonatal Neurology and Neurosurgery. M.I. Levene, F.A. Cherenak, M. Whittle, Eds 505 520. 3rd ed. Churchill Livingstone. London.
18. van Bel, F. F. Groenendaal. 2008. Long-term pharmacologic neuroprotection after birth asphyxia: where do we stand? Neonatology 94 : 203 210.
19. Röther, J. 2008. Neuroprotection does not work Stroke 39 : 523 524.
20. Hussain, M.S. A. Shuaib. 2008. Research into neuroprotection must continue but with a different approach. Stroke 39 : 521 522.
21. Clancy, B., B. Kersh, J. Hyde, et al. 2007. Web-based method for translating neurodevelopment from laboratory species to humans. Neuroinformatics 5 : 79 94.
22. Borlongan, C.V., Y. Wang T.P. Su. 2004. Delta opioid peptide [D-Ala2 D-Leu5] enkephalin: linking hibernation and neuroprotection. Frontiers Biosci. 9 : 3392 3398.
23. Drew, K.L., M.E. Rice, T.B. Kuhn, et al. 2001. Neuroprotective adaptations in hibernation: therapeutic implications for ischemia-reperfusion, traumatic brain injury and neurodegenerative diseases. Free Radic. Biol. Med. 31 : 563 573.
24. Drew, K.L., C.L. Buck, B.M. Barnes, et al. 2007. Central nervous system regulation of mammalian hibernation: implications for metabolic suppression and ischemia tolerance. J. Neurochem. 102 : 1713 1726.
25. Oeltgen, P.R., S.P. Nilekani, P.A. Nuchols, et al. 1988. Further studies on opioids and hibernation: delta opioid receptor ligand selectively induced hibernation in summer-active ground squirrels. Life Sci. 43 : 1565 1574.
26. Govindaswami, M., S.A. Brown, J. Yu, et al. 2008. Delta 2-specific opioid receptor agonist and hibernating woodchuck plasma fraction provide ischemic neuroprotection. Acad. Emerg. Med. 15 : 265 266.
27. Musacchia, X. 1959. The viability of Chrysemys picta submerged at various temperatures. Physiol. Zool. 32 : 47 50.
28. Xia, Y. G.G. Haddad. 2001. Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain. J. Comp. Neurol. 436 : 202 210.
29. Pamenter, M.E. L.T. Buck. 2008. delta-Opioid receptor antagonism induces NMDA receptor-dependent excitotoxicity in anoxic turtle cortex. J. Exp. Biol. 211 : 3512 3517.
30. Menger, M.D. B. Vollmar. 2007. Pathomechanisms of ischemia-reperfusion injury as the basis for novel preventive strategies: is it time for the introduction of pleiotropic compounds? Transplant Proc. 39 : 485 488.
31. + entry in mouse cortex. Cereb. Cortex. 18 : 2217 2227.
32. + leakage in the cortex. Cell Mol. Life Sci. 66 : 1105 1115.
33. +) influx in the cortex during acute hypoxia. J. Cell Physiol. 212 : 60 67.
34. +) channels. J. Physiol. 555 : 489 502.
35. Chao, D., D.F. Donnelly, Y. Feng, et al. 2007. Cortical delta-opioid receptors potentiate K+ homeostasis during anoxia and oxygen-glucose deprivation. J. Cereb. Blood Flow Metab. 27 : 356 368.
36. Glaum, S.R., R.J. Miller D.L. Hammond. 1994. Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord. J. Neurosci. 14 : 4965 4971.
37. Bie, B., W. Zhu Z.Z. Pan. 2009. Rewarding morphine-induced synaptic function of delta-opioid receptors on central glutamate synapses. J. Pharmacol. Exp. Ther. 329 : 290 296.
38. Zhu, M., M.W. Li, X.S. Tian, et al. 2009. Neuroprotective role of delta-opioid receptors against mitochondrial respiratory chain injury. Brain Res. 1252 : 183 191.
39. Peng, P.H., H.S. Huang, Y.J. Lee, et al. 2009. Novel role for the delta-opioid receptor in hypoxic preconditioning in rat retinas. J. Neurochem. 108 : 741 754.
40. Tsao, L.I., B. Ladenheim, A.M. Andrews, et al. 1998. Delta opioid peptide [D-Ala2,D-leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administrations of methamphetamine: involvement of opioid receptors and reactive oxygen species. J. Pharmacol. Exp. Ther. 287 : 322 331.
41. Davis, D.P. P.M. Patel. 2003. Ischemic preconditioning in the brain. Curr. Opin. Anaesthesiol. 16 : 447 452.
42. Dirnagl, U., R.P. Simon J.M. Hallenbeck. 2003. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 26 : 248 254.
43. Gross, G.J. 2003. Role of opioids in acute and delayed preconditioning. J. Mol. Cell. Cardiol. 35 : 709 718.
44. Zhang, J., H. Qian, P. Zhao, et al. 2006. Rapid hypoxia preconditioning protects cortical neurons from glutamate toxicity through delta-opioid receptor. Stroke 37 : 1094 1099.
45. Ma, M.C., H. Qian, F. Ghassemi, et al. 2005. Oxygen-sensitive [delta]-opioid receptor-regulated survival and death signals: novel insights into neuronal preconditioning and protection. J. Biol. Chem. 280 : 16208 16218.
46. Zhao, P., Y. Huang Z. Zuo. 2006. Opioid preconditioning induces opioid receptor-dependent delayed neuroprotection against ischemia in rats. J. Neuropathol. Exp. Neurol. 65 : 945 952.
47. Attali, B., D. Saya Z. Vogel. 1990. Pre- and postnatal development of opiate receptor subtypes in rat spinal cord. Brain Res. Dev. Brain Res. 53 : 97 102.
48. McDowell, J. I. Kitchen. 1986. Ontogenesis of delta-opioid receptors in rat brain using [3H][D-Pen2, D-Pen5]enkephalin as a binding ligand. Eur. J. Pharmacol. 128 : 287 289.
49. Szucs, M. C.J. Coscia. 1990. Evidence for delta-opioid binding and GTP-regulatory proteins in 5-day-old rat brain membranes. J. Neurochem. 54 : 1419 1425.
50. Milligan, G., R.A. Streaty, P. Gierschik, et al. 1987. Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain. J. Biol. Chem. 262 : 8626 8630.
51. Mailly, P., M. Gastard, A. Cupo. 1999. Subcellular distribution of delta-opioid receptors in the rat spinal cord: an approach using a three-dimensional reconstruction of confocal series of immunolabelled neurons. J. Neurosci. Methods 87 : 17 24.
52. Sales, N., Y. Charnay, J.M. Zajac, et al. 1989. Ontogeny of mu and delata opioid receptors and of neutral endopeptidase in human spinal cord: an autoradiographic study. J. Chem. Neuroanat. 2 : 179 188.
53. Zagon, I.S., D.M. Gibo P.J. McLaughlin. 1990. Adult and developing human cerebella exhibit different profiles of opioid binding sites. Brain Res. 523 : 62 68.
54. Scherrer, G., N. Imamachi, & Y.Q. Cao, et al. 2009. Dissociation of the opioid receptor mechanisms that control mechanical and heat pain. Cell 137 : 1148 1159.
55. Williams, S.A., T.J. Abbruscato, V.J. Hruby, et al. 1996. Passage of a delta-opioid receptor selective enkephalin, [D-penicillamine2,5] enkephalin, across the blood-brain and the blood-cerebrospinal fluid barriers. J. Neurochem. 66 : 1289 1299.
56. Ampasavate, C., G.A. Chandorkar, D.G. Vande Velde, et al. 2002. Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier. Int. J. Pharm. 233 : 85 98.
57. Horiuchi, T., M. Kawaguchi, T. Sakamoto, et al. 2004. The effects of the delta-opioid agonist SNC80 on hind-limb motor function and neuronal injury after spinal cord ischemia in rats. Anesth. Analg. 99 : 235 240.
58. Jha, A., S. Das Gupta S.B. Deshpande. 2003. Deprenyl blocks the aglycemia-induced depression of the synaptic transmission but not the ischemia-induced depression in neonatal rat spinal cord in vitro. Neurosci. Res. 47 : 23 29.
59. Freiberg, S.M. S.M. Johnson. 2008. Delta-opioid receptor (DOR) activation provides neuroprotection against oxygen-glucose deprivation (OGD) in neonatal spinal respiratory motor circuits in vitro. Soc. Neurosci. Abst. 152.2.
60. Shook, J.E., W.D. Watkins E.M. Camporesi. 1990. Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depression. Am. Rev. Respir. Dis. 142 : 895 909.
61. May, C.N., M.R. Dashwood, C.J. Whitehead, et al. 1989. Differential cardiovascular and respiratory responses to central administration of selective opioid agonists in conscious rabbits: correlation with receptor distribution. Br. J. Pharmacol. 98 : 903 913.
62. Kiritsy-Roy, J.A., L. Marson G.R. van Loon. 1989. Sympathoadrenal, cardiovascular and blood gas responses to highly selective Mu and Delta opioid peptides. J. Pharmacol. Exp. Ther. 251 : 1096 1103.
63. Su, Y.F., R. McNutt K.J. Chang. 1998. Delta-opioid ligand reverses alfentanil-induced respiratory depression not antinociception. J. Pharmacol. Exp. Ther. 287 : 815 823.
64. Clapp, J.F., A. Kett, N. Olariu, et al. 1997. Cardiovascular and metabolic responses to two receptor-selective opioid agonists in pregnant sheep. Am. J. Obstet. Gynecol. 178 : 397 401.
65. Szeto, H.H., Y. Soong, D. Wu, et al. 1999. Respiratory depression after intravenous administration of δ-selective opioid peptide analogs. Peptides 20 : 101 105.
66. Greer, J.J., J.E. Carter Z. al-Zubaidy. 1995. Opioid depression of respiration in neonatal rats. J. Physiol. 485 : 845 855.
67. Takita, K., E.A. Herlenius, S.G. Lindahl, et al. 1997. Actions of opioids on respiratory activity via activation of brainstem mu-, delta-, and kappa-receptors; an in-vitro study. Brain Res. 778 : 233 241.
68. Takeda, S., L.I. Eriksson, Y. Yamamoto, et al. 2001. Opioid action on respiratory neuron activity of the isolated respiratory network in newborn rats. Anesthesiology 95 : 740 749.
69. 2]deltorphin I. Eur. J. Pharmacol. 230 : 85 88. (Pubitemid 23024984)
70. Cheng, P.Y., D.L. Wu, Y. Soong, et al. 1993. Role of μ1 and δ-opioid receptors in modulation of fetal EEG and respiratory activity. Am. J. Physiol. 265 : R433 R438.
71. Szeto, H.H., P.Y. Cheng, Y. Soong, et al. 1995. Lack of relationship between opioid-induced changes in fetal breathing and plasma glucose levels. Am. J. Physiol. 269 : R702 R707.
72. Szeto, H.H., P.Y. Cheng, D.L. Wu, et al. 1994. Effects of the delta-opioid agonist, [D-Pen2, D-Pen5]-enkephalin, on fetal lamb EEG. Pharmacol. Biochem. Behav. 49 : 795 800.
73. Danielsson, I., M. Gasior, G.W. Stevenson, et al. 2006. Electroencephalographic and convulsant effects of the delta opioid agonist SNC80 in rhesus monkeys. Pharmacol. Biochem. Behav. 85 : 428 434.
74. Kakinohana, M., S. Nakamura, T. Fuchigami, et al. 2006. Mu and delta, but not kappa, opioid agonists induce spastic paraparesis after a short period of spinal cord ischaemia in rats. Br. J. Anaesth. 96 : 88 94.