Increased ratio of vascular endothelial growth factor to semaphorin3A is a negative prognostic factor in human meningiomas

Neuropathology

Volumn 30, Issue 5, 2010, Pages 537-546

  Barresi, Valeria ^a   Tuccari, Giovanni ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

meningioma; MVD; neo angiogenesis; NRP 1; SEMA3A; VEGF

Indexed keywords

NEUROPILIN 1; SEMAPHORIN 3A; VASCULOTROPIN; SEMA3A PROTEIN, HUMAN; VASCULOTROPIN A;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CLINICAL ARTICLE; FEMALE; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MALE; MENINGIOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR GROWTH; KAPLAN MEIER METHOD; MENINGEAL NEOPLASMS; METABOLISM; MICROVASCULATURE; MIDDLE AGED; MORTALITY; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MICROVESSELS; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; NEUROPILIN-1; PROGNOSIS; SEMAPHORIN-3A; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954563353     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2010.01105.x     Document Type: Article

References (39)

1. Perry A, Stafford SL, Scheithauer BW et al. "Malignancy" in meningiomas: a clinico-pathological study of 116 patients with grading implications. Cancer 1999 85 : 2046 2056.
2. Barresi V, Cerasoli S, Vitarelli E, Tuccari G. Density of microvessel positive for CD105 (endoglin) is related to prognosis in meningiomas. Acta Neuropathol 2007 114 : 147 156.
3. Barresi V, Vitarelli E, Cerasoli S. Semaphorin3A immunohistochemical expression in human meningiomas: correlation with the microvessel density. Virchows Arch 2009 454 : 563 571.
4. Perry A, Louis DN, Scheithauer BW et al. Meningiomas. In : Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, eds. WHO Classification of Tumors of the Central Nervous System. Lyon : IARCC press, 2007 164 172.
5. Barresi V, Cerasoli S, Tuccari G. Correlative evidence that tumor cell-derived caveolin-1 mediates angiogenesis in meningiomas. Neuropathology 2008 28 : 472 478.
6. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992 267 : 10931 10934.
7. Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997 18 : 4 25.
8. Christov C, Lechapt-Zalcman E, Adle-Biassette H, Nachev S, Gherardi RK. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptor flt-1 in microcystic meningiomas. Acta Neuropathol 1999 98 : 414 420.
9. Otsuka S, Tamiya T, Ono Y et al. The relationship between peritumoral brain edema and the expression of vascular endothelial growth factor and its receptors in intracranial meningiomas. J Neurooncol 2004 70 : 349 357.
10. Pistolesi S, Fontanini G, Camacci T et al. Meningioma-associated brain oedema: the role of angiogenic factors and pial blood supply. J Neurooncol 2002 60 : 159 164.
11. Pistolesi S, Boldrini L, Gisfredi S et al. Angiogenesis in intracranial meningiomas: immunohistochemical and molecular study. Neuropathol Appl Neurobiol 2004 30 : 118 125.
12. Nishikawa R, Cheng SY, Nagashima R, Huang HJ, Cavenee WK, Matsutani M. Expression of vascular endothelial growth factor in human brain tumors. Acta Neuropathol 1998 96 : 453 462.
13. Pietsch T, Valter MM, Wolf HK. Expression and distribution of vascular endothelial growth factor protein in human brain tumors. Acta Neuropathol 1997 93 : 109 117.
14. Maiuri F, De Caro Mdel B, Esposito F et al. Recurrences of meningiomas: predictive value of pathological features and hormonal and growth factors. J Neurooncol 2007 82 : 63 68.
15. Luo Y, Raible D, Raper JA. Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 1993 75 : 217 227.
16. Soker S, Takashima S, Miao HQ et al. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform specific receptor for vascular endothelial growth factor. Cell 1998 92 : 735 745.
17. Guttmann-Raviv N, Shraga-Heled N, Varshavsky A et al. Semaphorin-3A and semaphoring-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. J Biol Chem 2007 282 : 26294 26305.
18. Miao HQ, Soker S, Feiner L et al. Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. J Cell Biol 1999 12 : 233 242.
19. Soker S, Maio HQ, Nomi M et al. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165 receptor binding. J Biol Chem 2002 85 : 357 368.
20. Osada R, Horiuchi A, Kikuchi N et al. Expression of semaphorins, vascular endothelial growth factor and their common receptor neuropilins and allelic loss of semaphorin locus in epithaelial ovarian neoplasms: increased ratio of vascular endothelial growth factor to semaphoring is a poor prognostic factor in ovarian carcinomas. Hum Pathol 2006 37 : 1414 1425.
21. Simpson D. The recurrence of intracranial meningiomas after surgical treatment. J Neurol Neurosurg Psychiatry 1957 20 : 22 39.
22. Villegas G, Tufro A. Ontogeny of semaphorins 3A and 3F and their receptors neuropilins 1 and 2 in the kidney. Gene Expr Patterns 2002 2 : 151 155. (Pubitemid 36356030)
23. Gougos A, St Jacques S, Greaves A et al. Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells, leukemic cells, and syncytiotrophoblasts. Int Immunol 1992 4 : 83 92.
24. Perry A, Stafford SL, Scheithauer BW et al. The prognostic significance of MIB-1, p53, and DNA flow cytometry in completely resected primary meningiomas. Cancer 1998 82 : 2262 2269.
25. Miller DW, Graulich W, Karges B et al. Elevated expression of endoglin, a component of the TGF-β receptor complex, correlates with proliferation of tumour endothelial cells. Int J Cancer 1999 81 : 568 572.
26. Panagopoulos AT, Lancellotti CL, Veiga JC, de Aguiar PH, Colquhoun A. Expression of cell adhesion proteins and proteins related to angiogenesis and fatty acid metabolism in benign, atypical, and anaplastic meningiomas. J Neurooncol 2008 89 : 73 87.
27. Provias J, Claffey K, delAguila L, Lau N, Feldkamp M, Guha A. Meningiomas: role of vascular endothelial growth factor/vascular permeability factor in angiogenesis and peritumoral edema. Neurosurgery 1997 40 : 1016 1026. (Pubitemid 27202686)
28. Bachelder RE, Lipscomb EA, Lin X et al. Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Res 2003 63 : 5230 5233.
29. Vacca A, Scavelli C, Serini G et al. Loss of inhibitory semaphorin3A (sema3A) autocrine loops in bone marrow endothelial cells of patients with multiple myeloma. Blood 2006 108 : 1661 1667.
30. Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood 2001 98 : 1904 1913.
31. Catalano A, Caprari P, Rodilossi S et al. Cross-talk between vascular endothelial growth factor and semaphorin-3A pathway in the regulation of normal and malignant mesothelial cell proliferation. FASEB J 2004 18 : 358 360.
32. Kamitani H, Masuzawa H, Kanazawa I et al. Recurrence of convexity meningiomas: tumour cells in the arachnoid membrane. Surg Neurol 2001 56 : 228 235.
33. Kinjo T, al-Mefty O, Kanaan I. Grade zero removal of supratentorial convexity meningiomas. Neurosurgery 1993 33 : 394 399.
34. Pan Q, Chanthery Y, Liang WC et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell 2007 11 : 53 67.
35. Ding H, Wu X, Roncari L et al. Expression and regulation of neuropilin-1 in human astrocytomas. Int J Cancer 2000 88 : 584 592.
36. Hu B, Guo P, Bar-Joseph I et al. Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway. Oncogene 2007 26 : 5577 5586.
37. Marcus K, Johnson M, Adam RM et al. Tumor cell-associated neuropilin-1 and vascular endothelial growth factor expression as determinants of tumor growth in neuroblastoma. Neuropathology 2005 25 : 178 187.
38. Osada H, Tokunaga T, Nishi M et al. Overexpression of the neuropilin 1 (NRP1) gene correlated with poor prognosis in human glioma. Anticancer Res 2004 2B : 547 552.
39. Hansel DE, Wilentz RE, Yeo CJ, Schulick RD, Montgomery E, Maitra A. Expression of neuropilin-1 in high grade dysplasia, invasive cancer and metastases of the human gastro-intestinal tract. Am J Surg Pathol 2004 28 : 347 356.