Reduction of bone cancer pain by CB1 activation and TRPV1 inhibition

Journal of Anesthesia

Volumn 24, Issue 2, 2010, Pages 328-332

  Kawamata, Tomoyuki ^a,b   Niiyama, Yukitoshi ^a   Yamamoto, Jun ^a   Furuse, Shingo ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5' IODORESINIFERATOXIN; CANNABINOID 1 RECEPTOR; VANILLOID RECEPTOR 1;

ANALGESIC ACTIVITY; BONE CANCER; CANCER PAIN; CONFERENCE PAPER; DOWN REGULATION; NERVE CELL EXCITABILITY; NEUROPATHIC PAIN; NONHUMAN; PROTEIN EXPRESSION; QUALITY OF LIFE; SPINAL GANGLION; UPREGULATION;

ANIMALS; BONE NEOPLASMS; DISEASE MODELS, ANIMAL; DITERPENES; HUMANS; MICE; PAIN; RECEPTOR, CANNABINOID, CB1; TRPV CATION CHANNELS;

EID: 77954535910     PISSN: 09138668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00540-010-0919-0     Document Type: Conference Paper

References (17)

1. Schwei MJ, Honore P, Rogers SD, Salak-Johnson JL, Finke MP, Ramnaraine ML, Clohisy DR, Mantyh PW. Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci. 1999;19:10886-10897
2. Peters CM, Ghilardi JR, Keyser CP, Kubota K, Lindsay TH, Luger NM, Mach DB, Schwei MJ, Sevcik MA, Mantyh PW. Tumor-induced injury of primary afferent sensory nerve fibers in bone cancer pain. Exp Neurol. 2005;193:85-100.
3. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron. 1998;21:531-543
4. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000;288:306-313
5. Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2- yl)tetrahydropyrazine-1(2H)- carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties. II. In vivo characterization in rat models of inflammatory and neuropathic pain. J Pharmacol Exp Ther. 2003;306:387-393
6. Rashid MH, Inoue M, Bakoshi S, Ueda H. Increased expression of vanilloid receptor 1 on myelinated primary afferent neurons contributes to the antihyperanalgesic effect of capsaicin cream in diabetic neuropathic pain in mice. J Pharmacol Exp Ther. 2003;306:709-717
7. Niiyama Y, Kawamata T, Yamamoto J, Omote K, Namiki A. Bone cancer increases transient receptor potential vanilloid subfamily 1 expression within distinct subpopulations of dorsal root ganglion neurons. Neuroscience. 2007;148:560-572
8. Kawamata T, Ji W, Yamamoto J, Niiyama Y, Furuse S, Namiki A. Contribution of transient receptor potential vanilloid subfamily 1 to endothelin-1-induced thermal hyperalgesia. Neuroscience. 2008;154:1067-1076
9. Yamamoto J, Kawamata T, Niiyama Y, Omote K, Namiki A. Down-regulation of mu opioid receptor expression within distinct subpopulations of dorsal root ganglion neurons in a murine model of bone cancer pain. Neuroscience. 2008;151:65-72.
10. Niiyama Y, Kawamata T, Yamamoto J, Furuse S, Omote K, Namiki A. SB366791, a TRPV1 antagonist, potentiates analgesic effects of systemic morphine on bone cancer pain. Br J Anaesth. 2009;102:251-258
11. Morisset V, Urban L. Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. J Neurophysiol. 2001;86:40-48
12. Kelly S, Chapman V. Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo. J Neurophysiol. 2001;86:3061-3064
13. Sagar DR, Kelly S, Millns PJ, O'Shaughnessey CT, Kendall DA, Chapman V. Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats. Eur J Neurosci. 2005;22:371-379
14. Drew LJ, Harris J, Millns PJ, Kendall DA, Chapman V. Activation of spinal cannabinoid 1 receptors inhibits C-fibre driven hyperexcitable neuronal responses and increases [35S]GTPgammaS binding in the dorsal horn of the spinal cord of noninflamed and inflamed rats. Eur J Neurosci. 2000;12:2079-2086
15. Rahn EJ, Makriyannis A, Hohmann AG. Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats. Br J Pharmacol. 2007;152:765-777
16. Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci. 2007;10:870-879
17. Furuse S, Kawamata T, Yamamoto J, Niiyama Y, Omote K, Watanabe M, Namiki A. Reduction of bone cancer pain by activation of spinal cannabinoid receptor 1 and its expression in the superficial dorsal horn of the spinal cord in a murine model of bone cancer pain. Anesthesiology. 2009;111:173-186