In vitro evaluation of folic acid modified carboxymethyl chitosan nanoparticles loaded with doxorubicin for targeted delivery

Journal of Materials Science: Materials in Medicine

Volumn 21, Issue 5, 2010, Pages 1587-1597

  Sahu, Sumanta K ^a   Mallick, Sanjay K ^a   Santra, Susmita ^a   Maiti, Tapas K ^a   Ghosh, Sudip K ^a   Pramanik, Panchanan ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER DRUG; APOPTOSIS; AVERAGE SIZE; BIFUNCTIONAL; CANCER CELLS; CARBOXYMETHYL CHITOSAN; CELLULAR UPTAKE; COVALENTLY BONDED; DOXORUBICIN; DRUG CARRIER; DRUG LOADING; DRUG RELEASE PATTERNS; ETHYLAMINE; FLOW-CYTOMETRIC ANALYSIS; FOLIC ACIDS; IN-VITRO EVALUATION; PH SENSITIVE; TARGETED DELIVERY; TARGETED DRUG DELIVERY; TARGETED NANOPARTICLE;

CELL DEATH; CHITIN; CHITOSAN; CONFOCAL MICROSCOPY; DRUG DELIVERY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FOURIER TRANSFORMS; LIGHT TRANSMISSION; MULTILAYERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC ACIDS; RESONANCE; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; WAVELET TRANSFORMS;

NANOPARTICLES;

CHITOSAN DERIVATIVE; DOXORUBICIN; FOLIC ACID; NANOPARTICLE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CONFOCAL MICROSCOPY; COVALENT BOND; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; DRUG UPTAKE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

CHITOSAN; DOXORUBICIN; DRUG CARRIERS; FLOW CYTOMETRY; FOLIC ACID; HELA CELLS; HEMATINICS; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OXIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 77954534030     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-010-3998-4     Document Type: Article

References (38)

1. Uhrich KE, Cannizzaro SM, Langer RS, Shakesheff KM. Polymeric systems for controlled drug release. Chem Rev. 1999;99: 3181-3198
2. Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev. 2003;55:329-347
3. Marin RV, Ng CH, Wilke M, Tiersch B, Fratzl P, Peter MG. Sizecontrolled hydroxyapatite nanoparticles as self-organized organic-inorganic composite materials. Biomaterials. 2005;26: 5414-5426
4. Marinakos SM, Anderson MF, Ryan JA, Martin LD, Feldheim DL. Encapsulation, permeability, and cellular uptake characteristics of hollow nanometer-sized conductive polymer capsules. J Phys Chem B. 2001;105:8872-8876
5. Maeda H, Bharate GY, Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur J Pharm Biopharm. 2009;71:409-419
6. Faraji AH, Wipf P. Nanoparticles in cellular drug delivery. Bioorg Med Chem. 2009;17:2950-2962
7. Singh R, Lillard JW Jr. Nanoparticle-based targeted drug delivery. Exp Mol Pathol. 2009;86:215-223
8. Breunig M, Bauer S, Goepferich A. Polymers and nanoparticles: intelligent tools for intracellular targeting. Eur J Pharm Biopharm. 2008;68:112-128
9. Brannon-Peppas L, Blanchester JO. Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev. 2004;56:1649-1659
10. Vauthier C, Dubernet C, Chauvierre C, Brigger I, Couvreur P. Drug delivery to resistant tumors: the potential of poly(alkyl cyanoacrylate) nanoparticles. J Control Release. 2003;93:151-160
11. Liang HF, Chen CT, Chen SC, Kulkarni AR, Chiu YL, Chen MC, et al. Paclitaxel-loaded poly(g-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer. Biomaterials. 2006;27:2051-2059
12. Sheikh FA, Barakat NAM, Kanjwal MA, Aryal S, Khil MS, Kim HY. Novel self-assembled amphiphilic poly (epsilon-caprolactone)- grafted-poly (vinyl alcohol) nanoparticles: hydrophobic and hydrophilic drugs carrier nanoparticles. J Mater Sci: Mater Med. 2009;20:821-831
13. Mitra S, Gaur U, Ghosh PC, Maitra AN. Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. J Control Release. 2001;74:317-323
14. Ravi Kumar MNV, Muzzarelli RAA, Muzzarelli C, Sashiwa H, Domb AJ. Chitosan chemistry and pharmaceutical perspectives. Chem Rev. 2004;104:6017-6084
15. Yinsong W, Lingrong L, Jian W, Zhang Q. Preparation and characterization of self-aggregated nanoparticles of cholesterol-modi- Wed O-carboxymethyl chitosan conjugates. Carbohydr Polym. 2007; 69:597-606.
16. Weitman SD, Lark RH, Coney LR, Fort DW, Frasca V, Zurawski VRJ, et al. Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues. Cancer Res. 1992;52:3396-3401
17. Lee RJ, Low PS. Delivery of liposomes into cultured KB cells via folate receptor- mediated endocytosis. J Biol Chem. 1994;269: 3198-3204
18. Guo W, Hinkle GH, Lee RJ. Folate: a novel receptor-based targeted radiopharmaceutical for tumor imaging. J Nucl Med. 1999;40:1563-1569
19. Van Steenis JH, Van Maarseveen EM, Verbaan FJ, Verrijk R, Crommelin DJA. Preparation and characterization of folate-targeted pEG-coated pDMAEMA-based polyplexes. J Control Release. 2003; 87:167-176
20. Dauty E, Remy JS, Zuber G, Behr JP. Intracellular delivery of nanometric DNA particles via the folate receptor. Bioconjug Chem. 2002;13:831-839
21. Aronov O, Horowitz AT, Gabizon A, Gibson D. Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro Studies. Bioconjug Chem. 2003;14:563-574
22. Yoo HS, Park TG. Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Release. 2004;96:273-283
23. Hattori Y, Maitani Y. Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer. J Control Release. 2004;97:173-183
24. Ishida T, Kirchmeier MJ, Moase EH, Zalipsky S, Allen TM. Targeted delivery and triggered release of liposomal doxorubicin enhances cytotoxicity against human B lymphoma cells. Biochim Biophys Acta. 2001;1515:144-158
25. Yang Y, Jiang JS, Du B, Gan ZF, Qian M, Zhang P. Preparation and properties of a novel drug delivery system with both magnetic and biomolecular targeting. J Mater Sci: Mater Med. 2009; 20:301-307
26. Minkoa T, Batrakovab EV, Lib S, Lib Y, Pakunlua RI, Alakhovc VY, et al. Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells. J Control Release. 2005;105:269-278
27. Wang Y, Bansal V, Zelikin AN, Frank C. Templated synthesis of single-component polymer capsules and their application in drug delivery. Nano Lett. 2008;8:1741-1745
28. Engin K, Leeper DB, Cater JR, Thistlethwaite AJ, Tupchong L, McFarlane JD. Extracellular pH distribution in human tumors. Int J Hyperth. 1995;11:211-216
29. Ojugo ASE, Mesheehy PMJ, McIntyre DJO, McCoy C, Stubbs M, Leach MO, et al. Measurement of the extracellular pH of solid tumors in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes. NMR Biomed. 1999;12: 495-504.
30. Van Sluis R, Bhujwalla ZM, Ballerteros P, Alverez J, Cerdan S, Galons JP, et al. In vivo imaging of extracellular pH using 1H MSRI. Magn Reson Med. 1999;41:743-750
31. Decuzzi P, Ferrari M. The role of specific and non-specific interactions in receptor-mediated endocytosis of nanoparticles. Biomaterials. 2007;28:2915-2922
32. Park JS, Han TH, Lee KY, Han SS, Hwang JJ, et al. N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release. J Control Release. 2006;115:37-45.
33. Mellman I, Fuchs R, Helenius A. Acidification of the endocytic and exocytic pathways. Annu Rev Biochem. 1986;55:773-800.
34. Mohapatra S, Mallick SK, Maiti TK, Ghosh SK, Pramanik P. Synthesis of highly stable folic acid conjugated magnetite nanoparticles for targeting cancer cells. Nanotechnology. 2007; 18:385102-385111
35. Das M, Mishra D, Maiti TK, Basak A, Pramanik P. Bio-functionalization of magnetite nanoparticles using an aminophosphonic acid coupling agent: new, ultradispersed, iron-oxide folate nanoconjugates for cancer-specific targeting. Nanotechnology. 2008;19:415101-415115
36. Chen XG, Park HJ. Chemical characteristics of O-carboxymethyl chitosans related to the preparation conditions. Carbohydr Polym. 2003;53:355-359
37. Gabizon A, Horowitz AT, Goren D, Tzemach D, Shavit FM, Qazen MM, et al. Targeting folate receptor with folate linked to extremities of poly (ethylene glycol)-grafted liposomes: in vitro studies. Bioconjug Chem. 1999;10:289-298
38. Zhang Z, Lee SH, Feng SS. Folate-decorated poly (lactide-coglycolide)- vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials. 2007;28:1889-1899