Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene

Journal of Immunology

Volumn 184, Issue 9, 2010, Pages 5075-5084

  Fraser, Heather I ^a   Dendrou, Calliope A ^a   Healy, Barry ^a   Rainbow, Daniel B ^a   Howlett, Sarah ^a   Smink, Luc J ^a   Gregory, Simon ^b,d   Steward, Charles A ^b   Todd, John A ^a   Peterson, Laurence B ^c,e   Wicker, Linda S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c MERCK RESEARCH LABORATORIES   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IDD18 PROTEIN; IDD3 PROTEIN; INTERLEUKIN 2; NETRIN G1; PROTEIN; UNCLASSIFIED DRUG; VAV3 PROTEIN; INSULIN; NERVE PROTEIN; NETRIN-G1; VAV PROTEIN; VAV3 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DIABETES MELLITUS; AUTOIMMUNE DISEASE; C57BL 6 MOUSE; CHROMOSOME 13; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; EXON; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENE TARGETING; INTRON; MALE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SINGLE NUCLEOTIDE POLYMORPHISM; THYMOCYTE; ALLELE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHROMOSOME MAP; CONGENIC STRAIN; CROSS BREEDING; DISEASE MODEL; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; METHODOLOGY; PANCREAS ISLET BETA CELL; PATHOLOGY; PHYSIOLOGY;

ALLELES; ANIMALS; CROSSES, GENETIC; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; EXONS; FEMALE; GENE EXPRESSION REGULATION; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, INBRED NOD; NERVE TISSUE PROTEINS; PHYSICAL CHROMOSOME MAPPING; PROTO-ONCOGENE PROTEINS C-VAV;

EID: 77954504241     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903734     Document Type: Article

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