TBK1-targeted suppression of TRIF-dependent signaling pathway of toll-like receptor 3 by auranofin

Archives of Pharmacal Research

Volumn 33, Issue 6, 2010, Pages 939-945

  Park, Se Jeong ^a   Lee, A Neum ^a   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

Auranofin; IRF3; Poly I:C ; TBK1; Toll like receptors; TRIF

Indexed keywords

ADAPTOR PROTEIN; AURANOFIN; BINDING PROTEIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN ACTIVATOR BINDING KINASE 1; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL INTERLEUKIN 1 RECEPTOR DOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIRHEUMATIC AGENTS; ANTIVIRAL AGENTS; AURANOFIN; CELL LINE; CHEMOKINE CXCL10; GENES, REPORTER; HUMANS; INTERFERON INDUCERS; INTERFERON REGULATORY FACTOR-3; MICE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3;

EID: 77954478293     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0618-2     Document Type: Article

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