3,3′-Diindolylmethane suppresses 12-O-tetradecanoylphorbol-13- acetate-induced inflammation and tumor promotion in mouse skin via the downregulation of inflammatory mediators

Molecular Carcinogenesis

Volumn 49, Issue 7, 2010, Pages 672-683

  Kim, Eun Ji ^a   Park, Heesook ^a   Kim, Jongdai ^b   Park, Jung Han Yoon ^a  

^a Hallym University   (South Korea)

^b Kangwon National University   (South Korea)

Author keywords

Cyclooxygenase; Inducible nitric oxide synthase; Inflammation; NF B; Skin papilloma

Indexed keywords

3,3' DIINDOLYLMETHANE; CXCL11 CHEMOKINE; CYCLOOXYGENASE 2; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; SYNAPTOTAGMIN I; 3,3'-DIINDOLYLMETHANE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; AUTACOID; CXCL5 PROTEIN, MOUSE; I KAPPA B KINASE; INDOLE DERIVATIVE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; NOS2 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA BINDING; DNA MICROARRAY; DRUG STRUCTURE; EDEMA; FEMALE; GEL MOBILITY SHIFT ASSAY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CARCINOGENESIS; SKIN INFLAMMATION; SKIN TUMOR; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; EAR; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; PAPILLOMA; PATHOLOGY;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTICARCINOGENIC AGENTS; CHEMOKINE CXCL5; CYCLOOXYGENASE 2; EAR; EDEMA; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION; I-KAPPA B KINASE; INDOLES; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MICE; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PAPILLOMA; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 77954462453     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20640     Document Type: Article

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