-
1
-
-
28244471359
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). (1996) S2A. Specific Aspects of Regulatory Genotoxicity Tests for Pharmaceuticals
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). (1996) Guideline for Industry. S2A. Specific Aspects of Regulatory Genotoxicity Tests for Pharmaceuticals
-
Guideline for Industry
-
-
-
2
-
-
0345424863
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER)(1997) S2B. Genotoxicity: A Standard Battery for Genotoxicity Testing of Pharmaceuticals
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). (1997) Guidance for Industry. S2B. Genotoxicity: A Standard Battery for Genotoxicity Testing of Pharmaceuticals.
-
Guidance for Industry
-
-
-
3
-
-
2542510245
-
ICH-Harmonised guidances on genotoxicity testing of pharmaceuticals: Evolution, reasoning and impact
-
DOI 10.1016/S1383-5742(99)00004-6, PII S1383574299000046
-
Müller, L., Kikuchi, Y., Probst, G., Schechtman, L., Shimada, H., Sofuni, T. and Tweats, D. (1999) ICH-harmonized guidance on genotoxicity testing of pharmaceuticals; evolution, reasoning and impact. Mutat. Res., 436, 195-225 (Pubitemid 29246090)
-
(1999)
Mutation Research - Reviews in Mutation Research
, vol.436
, Issue.3
, pp. 195-225
-
-
Muller, L.1
Kikuchi, Y.2
Probst, G.3
Schechtman, L.4
Shimada, H.5
Sofuni, T.6
Tweats, D.7
-
4
-
-
84925559790
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) (1996) S1A. The Need for Long-term Rodent Carcinoge-nicity Studies of Pharmaceuticals
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) (1996) Guidelines for Industry. S1A. The Need for Long-term Rodent Carcinoge-nicity Studies of Pharmaceuticals
-
Guidelines for Industry
-
-
-
5
-
-
0345424863
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) (1997) S1B. Testing for Carcinogenicity of Pharmaceuticals
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) (1997) Guidance for Industry. S1B. Testing for Carcinogenicity of Pharmaceuticals.
-
Guidance for Industry
-
-
-
6
-
-
77954436403
-
-
Sweetman, S.C. (ed.) 35th edn. Pharmaceutical Press, London
-
Sweetman, S.C. (ed.) (2007) Martindale. The Complete Drug Reference. 35th edn. Pharmaceutical Press, London, pp. 1526-1602.
-
(2007)
Martindale. The Complete Drug Reference
, pp. 1526-1602
-
-
-
7
-
-
0035012857
-
A review of the genotoxicity of marketed pharmaceuticals
-
Snyder, R. D. and Green, J. W. (2001) A review of the genotoxicity of marketed pharmaceuticals. Mutat. Res., 488, 151-169.
-
(2001)
Mutat. Res.
, vol.488
, pp. 151-169
-
-
Snyder, R.D.1
Green, J.W.2
-
9
-
-
77954446139
-
Registry of toxic effects of chemical substances, 1985-1986
-
U.S. Department of Health and Human Sciences. (1988) Washington, DC: National Institute for Occupational Safety and Health. 10. 59th edn. Thomson PDR, Montvale, NJ
-
U.S. Department of Health and Human Sciences. (1988) Registry of Toxic Effects of Chemical Substances, 1985-1986. Washington, DC: National Institute for Occupational Safety and Health. 10. (2005) Physicians' Desk Reference. 59th edn. Thomson PDR, Montvale, NJ.
-
(2005)
Physicians' Desk Reference
-
-
-
10
-
-
0025058381
-
Genotoxicity of naturally occurring hydroxyanthra-quinones
-
Westendorf, J., Marquardt, H., Poginski, B., Dominiak, M., Schmidt, J. and Marquardt, H. (1990) Genotoxicity of naturally occurring hydroxyanthra-quinones. Mutat. Res., 240, 1-12.
-
(1990)
Mutat. Res.
, vol.240
, pp. 1-12
-
-
Westendorf, J.1
Marquardt, H.2
Poginski, B.3
Dominiak, M.4
Schmidt, J.5
Marquardt, H.6
-
11
-
-
0026699561
-
Mutagenicity of crude senna and senna glycosides in Salmonella typhimurium
-
Sandnes, D., Johansen, T., Teien, G. and Ulsaker, G. (1992) Mutagenicity of crude senna and senna glycosides in Salmonella typhimurium. Toxicology, 71, 165-172.
-
(1992)
Toxicology
, vol.71
, pp. 165-172
-
-
Sandnes, D.1
Johansen, T.2
Teien, G.3
Ulsaker, G.4
-
12
-
-
0026769537
-
The mutagenic constituents of rubia tinctorum
-
Kawasaki, Y., Goda, Y. and Yoshihira, K. (1992) The mutagenic constituents of rubia tinctorum. Chem. Pharm. Bull., 40, 1504-1509.
-
(1992)
Chem. Pharm. Bull.
, vol.40
, pp. 1504-1509
-
-
Kawasaki, Y.1
Goda, Y.2
Yoshihira, K.3
-
13
-
-
0027427672
-
The genotoxicity status of senna
-
Heidemann, A., Miltenburger, H. G. and Mengs, U. (1993) The genotoxicity status of senna. Pharmacology, 47 (Suppl. 1), 178-186. (Pubitemid 23291030)
-
(1993)
Pharmacology
, vol.47
, Issue.SUPPL. 1
, pp. 178-186
-
-
Heidemann, A.1
Miltenbuger, H.G.2
Mengs, U.3
-
15
-
-
0030005876
-
Genotoxicity of aloeemodin in vitro and in vivo
-
DOI 10.1016/0165-1218(95)00084-4
-
Heidemann, A., Voelkner, W. and Mengs, U. (1996) Genotoxicity of aloeemodin in vitro and in vivo. Mutat. Res., 367, 123-133. (Pubitemid 26099865)
-
(1996)
Mutation Research - Genetic Toxicology
, vol.367
, Issue.3
, pp. 123-133
-
-
Heidemann, A.1
Volkner, W.2
Mengs, U.3
-
16
-
-
84870940120
-
-
U.S. National Library of Medicine\Toxnet
-
U.S. National Library of Medicine\Toxnet, Toxicology Data Network. http://www.toxnet.nlm.nih.gov.
-
Toxicology Data Network
-
-
-
17
-
-
84925561127
-
-
FDA Center for Drug Evaluation and Research.
-
FDA, Center for Drug Evaluation and Research. http://www.fda.cder.
-
-
-
-
18
-
-
33645129908
-
Phenolphthalein and bisacodyl: Assessment of genotoxic and carcinogenic responses in heterozygous p53 (\+/-) mice and Syrian hamster embryo (SHE) assay
-
Stoll, R. E., Blanchard, K. T., Stoltz, J. H., Majerka, J. B., Furst, S., Lilly, P. D. and Mennear, J. H. (2006) Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (\+/-) mice and Syrian hamster embryo (SHE) assay. Toxicol. Sci., 90, 440-450.
-
(2006)
Toxicol. Sci.
, vol.90
, pp. 440-450
-
-
Stoll, R.E.1
Blanchard, K.T.2
Stoltz, J.H.3
Majerka, J.B.4
Furst, S.5
Lilly, P.D.6
Mennear, J.H.7
-
19
-
-
0023250909
-
Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals
-
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K. and Speck, W. (1987) Salmonella mutagenicity tests. Part III: results from the testing of 255 chemicals. Environ. Mol. Mutagen., 9 (Suppl. 9), 1-110. (Pubitemid 17115119)
-
(1987)
Environmental Mutagenesis
, vol.9
, Issue.SUPPL. 9
, pp. 1-110
-
-
Zeiger, E.1
Anderson, B.2
Haworth, S.3
-
20
-
-
84912912133
-
IARC monographs on the evaluation of carcinogenic risks to humans
-
International Agency for Research on Cancer IARC, Lyon, France
-
International Agency for Research on Cancer (1990) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol.50. Pharmaceutical Drugs, IARC, Lyon, France.
-
(1990)
Pharmaceutical Drugs
, vol.50
-
-
-
21
-
-
0024461339
-
Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro: II. Results with 20 chemicals
-
Loveday, K. S., Lugo, M. H., Resnick, M. A., Anderson, B. E. and Zeiger, E. (1989) Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro: II. Results with 20 chemicals. Envron. Mol. Mutagen., 13, 60-94 (Pubitemid 19252658)
-
(1989)
Environmental and Molecular Mutagenesis
, vol.13
, Issue.1
, pp. 60-94
-
-
Loveday, K.S.1
Lugo, M.H.2
Resnick, M.A.3
Anderson, B.E.4
Zeiger, E.5
-
23
-
-
0020693140
-
Mutagenicity of anthraquinones in the Salmonella preincubation test
-
Tikkanen, L., Matsushima, T. and Natori, S. (1983) Mutagenicity of anthraquinones in the Salmonella preincubation test. Mutat. Res., 116, 297-304. (Pubitemid 13184879)
-
(1983)
Mutation Research
, vol.116
, Issue.3-4
, pp. 297-304
-
-
Tikkanen, L.1
Matsushima, T.2
Natori, S.3
-
24
-
-
0026576710
-
Mutagenicity of substituted anthraquinones in the Ames/Salmonella microsome system
-
Krivobok, S., Seigle-Murandi, F., Steiman, R., Marzin, D. R. and Bettina, V. (1992) Mutagenicity of substituted anthraquinones in the Ames/Salmonella microsome system. Mutat. Res., 279, 1-8.
-
(1992)
Mutat. Res.
, vol.279
, pp. 1-8
-
-
Krivobok, S.1
Seigle-Murandi, F.2
Steiman, R.3
Marzin, D.R.4
Bettina, V.5
-
25
-
-
0023034964
-
The salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program
-
Kier, L. E., Brusick, D. J., Auletta, A. E. et al. (1986) The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 168, 69-240.
-
(1986)
Mutat. Res.
, vol.168
, pp. 69-240
-
-
Kier, L.E.1
Brusick, D.J.2
Auletta, A.E.3
-
26
-
-
0030596126
-
Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: Topoisomerase II mediated?
-
DOI 10.1016/S0165-1218(96)90105-6, PII S0165121896000924
-
Mueller, O., Eckart, I., Lutz, W. K. and Stopper, H. (1996) Genotoxicity of the laxative drug components emodin, aloe-emodin, and danthron in mammalian cells: topoisomerase mediated? Mutat. Res., 371, 165-173. (Pubitemid 27036279)
-
(1996)
Mutation Research - Genetic Toxicology
, vol.371
, Issue.3-4
, pp. 165-173
-
-
Muller, S.O.1
Eckert, I.2
Lutz, W.K.3
Stopper, H.4
-
27
-
-
0021243939
-
Genotoxicity of a variety of mycotoxins in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes
-
Mori, H., Kawai, K., Ohbayashi, F., Kuniyasu, T., Yamazaki, M., Hamasaki, T. and Williams, G. M. (1984) Genotoxicity of a variety od mycotoxins in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes. Cancer Res., 44, 2918-2923. (Pubitemid 14083209)
-
(1984)
Cancer Research
, vol.44
, Issue.7
, pp. 2918-2923
-
-
Mori, H.1
Kawai, K.2
Ohbayashi, F.3
-
28
-
-
0032507619
-
Factors affecting the genotoxic potency ranking of natural anthraquinones in mammalian cell culture systems
-
DOI 10.1016/S1383-5718(98)00047-3, PII S1383571898000473
-
Mueller, S. O., Lutz, W. K. and Stopper, H. (1998) Factors affecting the genotoxic potency ranking of natural anthraquinones in mammalian cell culture systems. Mutat. Res., 414, 125-129. (Pubitemid 28284946)
-
(1998)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.414
, Issue.1-3
, pp. 125-129
-
-
Mueller, S.O.1
Lutz, W.K.2
Stopper, H.3
-
29
-
-
0022515456
-
Carcinogenicity of chrysazin in large intestine and liver of mice
-
Mori, H., Sugie, S., Niwa, K., Yoshimi, N., Tanaka, T. and Hirono, I. (1986) Carcinogenicity of chrysazin in large intestine and liver of mice. Jap. J. Cancer Res. (GANN), 77, 871-876. (Pubitemid 16006780)
-
(1986)
Japanese Journal of Cancer Research
, vol.77
, Issue.9
, pp. 871-876
-
-
Mori, H.1
Sugie, S.2
Niwa, K.3
-
30
-
-
77954436954
-
-
National Cancer Institute/National Toxicology Program. U.S. Department of Health and Human Services. TR-446
-
(1996) NCI/NTP Carcinogenesis Technical Report Series. National Cancer Institute/National Toxicology Program. U.S. Department of Health and Human Services. TR-446.
-
(1996)
NCI/NTP Carcinogenesis Technical Report Series
-
-
-
31
-
-
0022458177
-
Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals
-
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T. and Mortelmans, K. (1988) Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals. Environ. Mol. Mutagen., 11 (Suppl. 12), 1-158. (Pubitemid 16084504)
-
(1986)
Environmental Mutagenesis
, vol.8
, Issue.SUPPL. 7
, pp. 1-119
-
-
Mortelmans, K.1
Haworth, S.2
Lawlor, T.3
-
32
-
-
77954440779
-
-
Technical Report Series 446 NUIHB publication no. 97-3362. U.S. Department of Health and Human Services, National Toxicology Program. National Institute of Environmental Health Sciences, Research Triangle Park, NC
-
(1996) Toxicology and carcinogenesis studies of 1-trans-delta-9-tetrahy- drocannabinol in F344 rats and B6C3F1 mice (gavage studies). Technical Report Series no. 446. NUIHB publication no. 97-3362. U.S. Department of Health and Human Services, National Toxicology Program. National Institute of Environmental Health Sciences, Research Triangle Park, NC.
-
(1996)
Toxicology and Carcinogenesis Studies of 1-trans-delta-9-tetrahy- drocannabinol in F344 Rats and B6C3F1 Mice (Gavage Studies)
-
-
-
33
-
-
0019483223
-
Sister-chromatid exchanges: A report of the GENE-TOX Program
-
Latt, S. A., Allen, J. and Bloom, S. E. (1981) Sister chromatid exchanges: a report of the Gene-Tox Program. Mutat. Res., 87, 17-62. (Pubitemid 11042443)
-
(1981)
Mutation Research
, vol.87
, Issue.1
, pp. 17-62
-
-
Latt, S.A.1
Allen, J.2
Bloom, S.E.3
-
34
-
-
0020554896
-
Cell transformation by chemical agents\a review ad analysis of the literature
-
Heidelberger, C., Freeman, A. E., Pienta, R. J. et al. (1983) Cell transformation by chemical agents\a review ad analysis of the literature. Mutat. Res., 114, 283-385.
-
(1983)
Mutat. Res.
, vol.114
, pp. 283-385
-
-
Heidelberger, C.1
Freeman, A.E.2
Pienta, R.J.3
-
35
-
-
0025352906
-
The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program
-
Mavournin, K. E., Blakey, D. H., Cimino, M. C., Salamone, M. F. and Heddle, J. A. (1990) The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 239, 29-80. (Pubitemid 20209463)
-
(1990)
Mutation Research
, vol.239
, Issue.1
, pp. 29-80
-
-
Mavournin, K.H.1
Blakey, D.H.2
Cimino, M.C.3
Salamone, M.F.4
Heddle, J.A.5
-
36
-
-
0020622741
-
An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals: A report of the U.S. Environmental Protection Agency Gene-Tox Program
-
Wyrobek, A. J., Gordon, L. A., Burkhart, J. G., Francis, M. W., Kapp, R. W., Jr., Letz, G., Malling, H. V., Topham, J. C. and Whorton, M. D. (1983) An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 115, 1-72. (Pubitemid 13122041)
-
(1983)
Mutation Research
, vol.115
, Issue.1
, pp. 1-72
-
-
Wyrobek, A.J.1
Gordon, L.A.2
Burkhart, J.G.3
-
37
-
-
77954434658
-
Toxicology and carcinogenesis studies of scopolamine hydrobromide trihydrate in F344/N rats and B6C3F1 mice (gavage studies)
-
National Toxicology Program
-
National Toxicology Program. (1997) Toxicology and carcinogenesis studies of scopolamine hydrobromide trihydrate in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol. Progr. Tech. Rep. Ser., 445.
-
(1997)
Natl Toxicol. Progr. Tech. Rep. Ser.
, vol.445
-
-
-
38
-
-
33748178209
-
DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assays
-
DOI 10.1016/j.mrgentox.2006.06.001, PII S1383571806001586
-
Snyder, R. D., Ewing, D. and Hendry, L. B. (2006) DNA intercalative potential of marketed drugs testing positive in in vitro assays. Mutat. Res., 609, 47-59. (Pubitemid 44311611)
-
(2006)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.609
, Issue.1
, pp. 47-59
-
-
Snyder, R.D.1
Ewing, D.2
Hendry, L.B.3
-
39
-
-
0028556222
-
Mutagenicity study of mesalazine
-
Nagasawa, Y., Miwa, Y., Hongyo, T., Sugawara, M. and Kawase, S. (1994) Mutagenicity study of mesalazine. Oyo Yakuri, 48, 501-509.
-
(1994)
Oyo Yakuri
, vol.48
, pp. 501-509
-
-
Nagasawa, Y.1
Miwa, Y.2
Hongyo, T.3
Sugawara, M.4
Kawase, S.5
-
40
-
-
0024401672
-
Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: Results with 27 chemicals
-
Loveday, K. S., Anderson, B. E., Resnick, M. A. and Zeiger, E. (1990) Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro. Part V: results with 46 chemicals. Environ. Mol. Mutagen., 16, 272-303. (Pubitemid 19245677)
-
(1989)
Environmental and Molecular Mutagenesis
, vol.13
, Issue.2
, pp. 133-193
-
-
Gulati, D.K.1
Witt, K.2
Anderson, B.3
Zeiger, E.4
Shelby, M.D.5
-
41
-
-
0028954935
-
Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells
-
Martelli, A., Brambilla Campart, G., Canonero, R., Mattioli, F. and Brambilla, G. (1995) Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells. Toxicol. Appl. Pharmacol., 131, 185-191.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.131
, pp. 185-191
-
-
Martelli, A.1
Brambilla Campart, G.2
Canonero, R.3
Mattioli, F.4
Brambilla, G.5
-
42
-
-
0028918417
-
Evaluation of DNA-damaging clastogenic, and promoting activity of metoclopramide and procainamide in rats
-
Mereto, E., Robbiano, L., Ghia, M., Allavena, A., Martelli, A. and Brambilla, G. (1995) Evaluation of DNA-damaging, clastogenic, and promoting activity of metoclopramide and procainamide in rats. Toxicol. Appl. Pharmacol., 131, 192-197.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.131
, pp. 192-197
-
-
Mereto, E.1
Robbiano, L.2
Ghia, M.3
Allavena, A.4
Martelli, A.5
Brambilla, G.6
-
43
-
-
0031737429
-
Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays
-
DOI 10.1016/S0300-483X(98)00101-2, PII S0300483X98001012
-
Martelli, A., Mattioli, F., Mereto, E., Brambilla Campart, G., Sini, D., Bergamaschi, G. and Brambilla, G. (1998) Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays. Toxicology, 130, 29-41. (Pubitemid 28488573)
-
(1998)
Toxicology
, vol.130
, Issue.1
, pp. 29-41
-
-
Martelli, A.1
Mattioli, F.2
Mereto, E.3
Brambilla Campart, G.4
Sini, D.5
Bergamaschi, G.6
Brambilla, G.7
-
44
-
-
0027217202
-
Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase
-
Crofton-Sleigh, C., Doherty, A., Ellard, S., Parry, E. M. and Venit, S. (1993) Micronucleus assay using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochrome P-450 and microsomal epoxide hydrolase. Mutagenesis, 8, 363-372. (Pubitemid 23226781)
-
(1993)
Mutagenesis
, vol.8
, Issue.4
, pp. 363-372
-
-
Crofton-Sleigh, C.1
Doherty, A.2
Ellard, S.3
Parry, E.M.4
Venitt, S.5
-
45
-
-
0027265409
-
Lack of evidence of omeprazole genotoxicity in Sprague-Dawley rats
-
Mereto, E., Ghia, M., Martelli, A. and Brambilla, G. (1993) Lack of evidence of omeprazole genotoxicity in Sprague-Dawley rats. Mutagenesis, 8, 379-386 (Pubitemid 23273979)
-
(1993)
Mutagenesis
, vol.8
, Issue.5
, pp. 379-386
-
-
Mereto, E.1
Ghia, M.2
Martelli, A.3
Brambilla, G.4
-
46
-
-
33845690718
-
-
International Agency for Research on Cancer. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. IARC, Lyon, France
-
International Agency for Research on Cancer. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. (2000). Some Antiviral and Antineoplastic Drugs and Other Pharmaceutical Agents. Vol.76. IARC, Lyon, France.
-
(2000)
Some Antiviral and Antineoplastic Drugs and Other Pharmaceutical Agents
, vol.76
-
-
-
47
-
-
0022458177
-
Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals
-
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B. and Zeiger, E. (1986) Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ. Mutagen., 8 (Suppl. 7), 1-119. (Pubitemid 16084504)
-
(1986)
Environmental Mutagenesis
, vol.8
, Issue.SUPPL. 7
, pp. 1-119
-
-
Mortelmans, K.1
Haworth, S.2
Lawlor, T.3
-
48
-
-
0023609111
-
Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals
-
Galloway, S. M., Armstrong, M. J., Reuben, C. et al. (1987) Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluation of 108 chemicals. Environ. Mol. Mutagen., 10 (Suppl. 10), 1-175. (Pubitemid 18039247)
-
(1987)
Environmental and Molecular Mutagenesis
, vol.10
, Issue.SUPPL. 10
, pp. 1-175
-
-
Galloway, S.M.1
Armstrong, M.J.2
Reuben, C.3
Colman, S.4
Brown, B.5
Cannon, C.6
Bloom, A.D.7
Nakamura, F.8
Ahmed, M.9
Duk, S.10
Rimpo, J.11
Margolin, B.H.12
Resnick, M.A.13
Anderson, B.14
Zeiger, E.15
-
49
-
-
0021230015
-
Chromosome mutation tests for mutagenesis in Drosophila melanogaster. A report of the U.S. Environmental Protection Agency Gene-Tox Program
-
Valencia, R., Abrahamson, S., Lee, W. R., Von Halle, E. S., Woodruff, R. C., Wuergler, F. E. and Zimmering, S. (1984) Chromosome mutation tests for mutagenesis in Drosophila melanogaster. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 134, 61-88. (Pubitemid 14097629)
-
(1984)
Mutation Research
, vol.134
, Issue.1
, pp. 61-88
-
-
Valencia, R.1
Abrahamson, S.2
Lee, W.R.3
-
50
-
-
0021278672
-
Mutagenicity tests of ranitidine hydrochloride
-
Okumura, K., Morita, T., Nagaki, T., Watanabe, Y. and Tsuji, H. (1984) Mutagenicity tests of ranitidine hydrochloride. Oyo Yakuri, 28, 163-169. (Pubitemid 14067234)
-
(1984)
Pharmacometrics
, vol.28
, Issue.1
, pp. 163-169
-
-
Okumura, K.1
Morita, T.2
Nagaki, T.3
-
51
-
-
0020638780
-
Genotoxicity of nitrosated ranitidine
-
De Flora, S., Bennicelli, C., Camoirano, A. and Zanacchi, P. (1983) Genotoxicity of nitrosated ranitidine. Carcinogenesis, 4, 255-260. (Pubitemid 13091939)
-
(1983)
Carcinogenesis
, vol.4
, Issue.3
, pp. 255-260
-
-
De Flora, S.1
Bennicelli, C.2
Camoirano, A.3
-
52
-
-
0020601054
-
DNA damage induced by nitrosated ranitidine in cultured mammalian cells
-
Maura, A., Pino, A., Robbiano, L., Cajelli, E., Finollo, R., Cavanna, M. and Brambilla, G. (1983) DNA damage induced by nitrosated ranitidine in cultured mammalian cells. Toxicol. Lett., 18, 97-102. (Pubitemid 13048000)
-
(1983)
Toxicology Letters
, vol.18
, Issue.1-2
, pp. 97-102
-
-
Maura, A.1
Pino, A.2
Robbiano, L.3
-
53
-
-
0021032742
-
Unscheduled DNA synthesis induced by nitrosated ranitidine in primary cultures of rat hepatocytes
-
Martelli, A., Fugassa, E., Voci, A. and Brambilla, G. (1983) Unscheduled DNA synthesis induced by nitrosated ranitidine in primary cultures of rat hepatocytes. Mutat. Res., 122, 373-376. (Pubitemid 14219255)
-
(1983)
Mutation Research
, vol.122
, Issue.3-4
, pp. 373-376
-
-
Martelli, A.1
Fugassa, E.2
Voci, A.3
Brambilla, G.4
-
54
-
-
0021030060
-
Genotoxic effects in rodents given high oral doses of ranitidine and sodium nitrite
-
Brambilla, G., Cavanna, M., Faggin, P., Maura, A., Pino, A., Ricci, R. and Robbiano, L. (1983) Genotoxic effects in rodents given high oral doses of ranitidine and sodium nitrite. Carcinogenesis, 4, 1281-1285. (Pubitemid 14229456)
-
(1983)
Carcinogenesis
, vol.4
, Issue.10
, pp. 1281-1285
-
-
Brambilla, G.1
Cavanna, M.2
Faggin, P.3
-
55
-
-
0031041992
-
Mechanistic studies on genotoxicity and carcinogenicity of salicylazosulfapyridine an anti-inflammatory medicine
-
Iatropoulos, M. J., Williams, G. M., Abdo, K. M., Kari, F. W. and Hart, R. W. (1997) Mechanistic studies on genotoxicity and carcinogenicity of salicylazosulfapyridine an anti-inflammatory medicine. Exp. Toxicol. Pathol., 49, 15-28.
-
(1997)
Exp. Toxicol. Pathol.
, vol.49
, pp. 15-28
-
-
Iatropoulos, M.J.1
Williams, G.M.2
Abdo, K.M.3
Kari, F.W.4
Hart, R.W.5
-
56
-
-
84925559665
-
Toxicology and carcinogenesis studies of salicylazosulfapyridine (CAS No. 599-79-1) in F344/N rats and B6C3F1 mice (gavage studies)
-
National Toxicology Program (1997) Toxicology and carcinogenesis studies of salicylazosulfapyridine (CAS No. 599-79-1) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol. Program Tech. Rep. Ser., 457.
-
(1997)
Natl Toxicol. Program Tech. Rep. Ser.
, vol.457
-
-
Toxicology Program, N.1
-
57
-
-
0023855146
-
A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures
-
Ishidate, M., Jr., Harnois, M. C. and Sofuni, T. (1988) A comprehensive analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures. Mutat. Res., 195, 151-213. (Pubitemid 18066068)
-
(1988)
Mutation Research
, vol.195
, Issue.2
, pp. 151-213
-
-
Ishidate Jr., M.1
Harnois, M.C.2
Sofuni, T.3
-
58
-
-
67349136621
-
Genotoxicity and carcinogenicity studies of analgesics anti-inflammatory drugs and antipyretics
-
Brambilla, G. and Martelli, A. (2009) Genotoxicity and carcinogenicity studies of analgesics, anti-inflammatory drugs and antipyretics. Pharmacol. Res., 60, 1-17.
-
(2009)
Pharmacol. Res.
, vol.60
, pp. 1-17
-
-
Brambilla, G.1
Martelli, A.2
-
59
-
-
36249013225
-
Genotoxicity and carcinogenicity studies of benzodiazepines
-
DOI 10.1016/j.phrs.2007.08.006, PII S1043661807001582
-
Brambilla, G., Carrozzino, R. and Martelli, A. (2007) Genotoxicity and carcinogenicity studies of benzodiazepines. Pharmacol. Res., 56, 443-458. (Pubitemid 350137767)
-
(2007)
Pharmacological Research
, vol.56
, Issue.6
, pp. 443-458
-
-
Brambilla, G.1
Carrozzino, R.2
Martelli, A.3
-
60
-
-
0023239438
-
A comprehensive analysis of data on the clastogenicity genesis in rodents from in vitro genetic toxicity assays
-
Tennant, R. W., Margolin, B. H., Shelby, M. D. et al. (1987) A comprehensive analysis of data on the clastogenicity genesis in rodents from in vitro genetic toxicity assays. Science, 236, 933-941.
-
(1987)
Science
, vol.236
, pp. 933-941
-
-
Tennant, R.W.1
Margolin, B.H.2
Shelby, M.D.3
-
61
-
-
0025184162
-
Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: Confirming of earlier results with 41 additional chemicals
-
Zeiger, E., Haseman, J. K., Shelby, M. D., Margolin, B. H. and Tennant, R. W. (1990) Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals. Environ. Mol. Mutagen., 16 (Suppl. 18), 1-14. (Pubitemid 20376833)
-
(1990)
Environmental and Molecular Mutagenesis
, vol.16
, Issue.SUPPL. 18
, pp. 1-14
-
-
Zeiger, E.1
Haseman, J.K.2
Shelby, M.D.3
Margolin, B.H.4
Tennant, R.W.5
-
62
-
-
21544473568
-
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens: I. Sensitivity, specificity and relative predictivity
-
DOI 10.1016/j.mrgentox.2005.02.004, PII S1383571805000835
-
Kirkland, D. J., Aardema, M., Henderson, L. and Muller, L. (2005) Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity. Mutat. Res., 584, 1-256. (Pubitemid 40922793)
-
(2005)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.584
, Issue.1-2
, pp. 1-256
-
-
Kirkland, D.1
Aardema, M.2
Henderson, L.3
Muller, L.4
-
63
-
-
33846237598
-
th IWGT, San Francisco, 9-10 September 2005
-
th IWGT, San Francisco, 9-10 September 2005. Mutat. Res., 627, 5-9.
-
(2005)
Mutat. Res.
, vol.627
, pp. 5-9
-
-
Kirkland, D.J.1
Hayashi, M.2
Jacobson-Kram, D.3
Kasper, P.4
MacGregor, J.T.5
Muller, L.6
Uno, Y.7
-
64
-
-
33846165551
-
Strategy for genotoxicity testing: Hazard identification and risk assessment in relation to in vitro testing
-
DOI 10.1016/j.mrgentox.2006.10.003, PII S1383571806003706, Reports of the 4th International Workshop on Genotoxicity Testing (IWGT), September 9-10, 2005, San Francisco, CA, USA
-
Thybaud, V., Aardema, M., Clements, J. et al. (2007) Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing. Mutat. Res., 627, 41-58. (Pubitemid 46091766)
-
(2007)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.627
, Issue.1
, pp. 41-58
-
-
Thybaud, V.1
Aardema, M.2
Clements, J.3
Dearfield, K.4
Galloway, S.5
Hayashi, M.6
Jacobson-Kram, D.7
Kirkland, D.8
MacGregor, J.T.9
Marzin, D.10
Ohyama, W.11
Schuler, M.12
Suzuki, H.13
Zeiger, E.14
-
65
-
-
33846186786
-
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests. I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards
-
DOI 10.1016/j.mrgentox.2006.10.005, PII S138357180600372X, Reports of the 4th International Workshop on Genotoxicity Testing (IWGT), September 9-10, 2005, San Francisco, CA, USA
-
Tweats, D. J., Blakey, D., Heflich, R. H. et al. (2007) Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests. I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards. Mutat. Res., 627, 78-91. (Pubitemid 46098931)
-
(2007)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.627
, Issue.1
, pp. 78-91
-
-
Tweats, D.J.1
Blakey, D.2
Heflich, R.H.3
Jacobs, A.4
Jacobsen, S.D.5
Morita, T.6
Nohmi, T.7
O'Donovan, M.R.8
Sasaki, Y.F.9
Sofuni, T.10
Tice, R.11
-
66
-
-
0038351753
-
IARC monographs on the evaluation of carcinogenic risks to humans supplement 7
-
International Agency for Research on Cancer IARC, Lyon, France
-
International Agency for Research on Cancer. (1987) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Supplement 7. Overall Evaluation of Carcinogenicity: An Updating of IARC Monographs, Vol.1-42. IARC, Lyon, France.
-
(1987)
Overall Evaluation of Carcinogenicity: An Updating of IARC Monographs
, vol.1-42
-
-
-
67
-
-
33947600311
-
Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products
-
DOI 10.1016/j.mrrev.2006.09.003, PII S1383574206000937
-
Brambilla, G. and Martelli, A. (2007) Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products. Mutat. Res., 635, 17-52. (Pubitemid 46482377)
-
(2007)
Mutation Research - Reviews in Mutation Research
, vol.635
, Issue.1
, pp. 17-52
-
-
Brambilla, G.1
Martelli, A.2
|