-
1
-
-
10744233432
-
Intensity-modulated radiotherapy (IMRT): The most important advance in radiotherapy since the linear accelerator?
-
Nutting C. Intensity-modulated radiotherapy (IMRT): The most important advance in radiotherapy since the linear accelerator? Br J Radiol 2003;76:673.
-
(2003)
Br J Radiol
, vol.76
, pp. 673
-
-
Nutting, C.1
-
2
-
-
44649092578
-
New developments in radiation therapy for head and neck cancer: Intensity-modulated radiation therapy and hypoxia targeting
-
Lee NY, Le QT. New developments in radiation therapy for head and neck cancer: Intensity-modulated radiation therapy and hypoxia targeting. Semin Oncol 2008;35:236-250
-
(2008)
Semin Oncol
, vol.35
, pp. 236-250
-
-
Lee, N.Y.1
Le, Q.T.2
-
3
-
-
35348837437
-
A phase i study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer
-
Guerrero Urbano T, Clark CH, Hansen VN, Adams EJ, A'Hern R, Miles EA, et al. A phase I study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer. Radiother Oncol 2007;85:36-41.
-
(2007)
Radiother Oncol
, vol.85
, pp. 36-41
-
-
Guerrero Urbano, T.1
Clark, C.H.2
Hansen, V.N.3
Adams, E.J.4
A'Hern, R.5
Miles, E.A.6
-
4
-
-
34547814325
-
Intensity modulated radiotherapy improves target coverage and parotid gland sparing when delivering total mucosal irradiation in patients with squamous cell carcinoma of head and neck of unknown primary site
-
Bhide S, Clark C, Harrington K, Nutting CM. Intensity modulated radiotherapy improves target coverage and parotid gland sparing when delivering total mucosal irradiation in patients with squamous cell carcinoma of head and neck of unknown primary site. Med Dosim 2007;32:188-195
-
(2007)
Med Dosim
, vol.32
, pp. 188-195
-
-
Bhide, S.1
Clark, C.2
Harrington, K.3
Nutting, C.M.4
-
5
-
-
28944440684
-
The impact of introducing intensity modulated radiotherapy into routine clinical practice
-
Miles EA, Clark CH, Urbano MT, Bidmead M, Dearnaley DP, Harrington KJ, et al. The impact of introducing intensity modulated radiotherapy into routine clinical practice. Radiother Oncol 2005;77:241-246
-
(2005)
Radiother Oncol
, vol.77
, pp. 241-246
-
-
Miles, E.A.1
Clark, C.H.2
Urbano, M.T.3
Bidmead, M.4
Dearnaley, D.P.5
Harrington, K.J.6
-
6
-
-
0034681783
-
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data
-
MACHNC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer
-
Pignon JP, Bourhis J, Domenge C, Designé L.Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data. MACHNC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949-955
-
(2000)
Lancet
, vol.355
, pp. 949-955
-
-
Pignon, J.P.1
Bourhis, J.2
Domenge, C.3
Designé, L.4
-
7
-
-
2342592623
-
Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer
-
DOI 10.1056/NEJMoa032641
-
Bernier J, Domenge C, Ozsahin M, Matuszewska K, Lefèbvre JL, Greiner RH, et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350:1945-1952 (Pubitemid 38580197)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.19
, pp. 1945-1952
-
-
Bernier, J.1
Domenge, C.2
Ozsahin, M.3
Matuszewska, K.4
Lefebvre, J.-L.5
Greiner, R.H.6
Giralt, J.7
Maingon, P.8
Rolland, F.9
Bolla, M.10
Cognetti, F.11
Bourhis, J.12
Kirkpatrick, A.13
Van Glabbeke, M.14
-
8
-
-
2342517421
-
Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
-
Cooper JS, Pajak TF, Forastiere AA, Jacobs J, Campbell BH, Saxman SB, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-1944
-
(2004)
N Engl J Med
, vol.350
, pp. 1937-1944
-
-
Cooper, J.S.1
Pajak, T.F.2
Forastiere, A.A.3
Jacobs, J.4
Campbell, B.H.5
Saxman, S.B.6
-
9
-
-
44949120769
-
Molecular pathogenesis of head and neck cancers
-
Singh B. Molecular pathogenesis of head and neck cancers. J Surg Oncol 2008;97:634-639
-
(2008)
J Surg Oncol
, vol.97
, pp. 634-639
-
-
Singh, B.1
-
10
-
-
37748998995
-
Biology of cancer
-
Harrington KJ. Biology of cancer. Medicine 2008;36:1-5.
-
(2008)
Medicine
, vol.36
, pp. 1-5
-
-
Harrington, K.J.1
-
11
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
17744373466
-
Biological signifi cance of c-erbB family oncogenes in head and neck cancer
-
Rogers SJ, Harrington KJ, Rhys-Evans P, O-Charoenrat P, Eccles SA. Biological signifi cance of c-erbB family oncogenes in head and neck cancer. Cancer Metastasis Rev 2005;24:47-69.
-
(2005)
Cancer Metastasis Rev
, vol.24
, pp. 47-69
-
-
Rogers, S.J.1
Harrington, K.J.2
Rhys-Evans, P.3
O-Charoenrat, P.4
Eccles, S.A.5
-
13
-
-
0037190809
-
The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors
-
Khademi B, Shirazi FM, Vasei M, Doroudchi M, Gandomi B, Modjtahedi H, et al. The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors. Cancer Lett 2002;184:223-230
-
(2002)
Cancer Lett
, vol.184
, pp. 223-230
-
-
Khademi, B.1
Shirazi, F.M.2
Vasei, M.3
Doroudchi, M.4
Gandomi, B.5
Modjtahedi, H.6
-
14
-
-
0027359459
-
Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer
-
Dassonville O, Formento JL, Francoual M, Ramaioli A, Santini J, Schneider M, et al. Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J Clin Oncol 1993;11:1873-1878
-
(1993)
J Clin Oncol
, vol.11
, pp. 1873-1878
-
-
Dassonville, O.1
Formento, J.L.2
Francoual, M.3
Ramaioli, A.4
Santini, J.5
Schneider, M.6
-
15
-
-
0030200866
-
The signifi cance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity
-
Kusukawa J, Harada H, Shima I, Sasaguri Y, Kameyama T, Morimatsu M. The signifi cance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity. Eur J Cancer B Oral Oncol 1996;32:217-221
-
(1996)
Eur J Cancer B Oral Oncol
, vol.32
, pp. 217-221
-
-
Kusukawa, J.1
Harada, H.2
Shima, I.3
Sasaguri, Y.4
Kameyama, T.5
Morimatsu, M.6
-
16
-
-
0036024532
-
The role of c-erbB receptors and ligands in head and neck squamous cell carcinoma
-
O-charoenrat P, Rhys-Evans PH, Modjtahedi H, Eccles SA.The role of c-erbB receptors and ligands in head and neck squamous cell carcinoma. Oral Oncol 2002;38:627-650
-
(2002)
Oral Oncol
, vol.38
, pp. 627-650
-
-
O-Charoenrat, P.1
Rhys-Evans, P.H.2
Modjtahedi, H.3
Eccles, S.A.4
-
17
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
-
Downward J, Yarden Y, Mayes E, Scrace G, Totty N, Stockwell P, et al. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature 1984;307:521-527
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
Scrace, G.4
Totty, N.5
Stockwell, P.6
-
18
-
-
0027183870
-
Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
-
Grandis JR, Tweardy DJ. Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.Cancer Res 1993;53:3579-3584
-
(1993)
Cancer Res
, vol.53
, pp. 3579-3584
-
-
Grandis, J.R.1
Tweardy, D.J.2
-
19
-
-
0028292482
-
Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis
-
Shin DM, Ro JY, Hong WK, Hittelman WN. Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994;54:3153-3159
-
(1994)
Cancer Res
, vol.54
, pp. 3153-3159
-
-
Shin, D.M.1
Ro, J.Y.2
Hong, W.K.3
Hittelman, W.N.4
-
20
-
-
0013650320
-
Asynchronous modulation of transforming growth factor alpha and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma
-
Rubin Grandis J, Tweardy DJ, Melhem MF. Asynchronous modulation of transforming growth factor alpha and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma. Clin Cancer Res 1998;4:13-20.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 13-20
-
-
Rubin Grandis, J.1
Tweardy, D.J.2
Melhem, M.F.3
-
21
-
-
0031426819
-
Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck
-
Ibrahim SO, Vasstrand EN, Liavaag PG, Johannessen AC, Lillehaug JR. Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck. Anticancer Res 1997;17:4539-4546
-
(1997)
Anticancer Res
, vol.17
, pp. 4539-4546
-
-
Ibrahim, S.O.1
Vasstrand, E.N.2
Liavaag, P.G.3
Johannessen, A.C.4
Lillehaug, J.R.5
-
22
-
-
0033990714
-
Clinical relevance of erbB-1 and-2 oncogenes in oral carcinomas
-
Werkmeister R, Brandt B, Joos U. Clinical relevance of erbB-1 and-2 oncogenes in oral carcinomas. Oral Oncol 2000;36:100-105
-
(2000)
Oral Oncol
, vol.36
, pp. 100-105
-
-
Werkmeister, R.1
Brandt, B.2
Joos, U.3
-
23
-
-
0032085325
-
Immunohistochemical analysis of the oncoprotein c-erbB-2 expression in oral benign and malignant lesions
-
Wilkman TS, Hietanen JH, Malmström MJ, Konttinen YT. Immunohistochemical analysis of the oncoprotein c-erbB-2 expression in oral benign and malignant lesions. Int J Oral Maxillofac Surg 1998;27:209-212
-
(1998)
Int J Oral Maxillofac Surg
, vol.27
, pp. 209-212
-
-
Wilkman, T.S.1
Hietanen, J.H.2
Malmström, M.J.3
Konttinen, Y.T.4
-
24
-
-
0038538474
-
Comparison of gene expression between metastatic derivatives and their poorly metastatic parental cells implicates crucial tumor-environment interaction in metastasis of head and neck squamous cell carcinoma
-
Chen Z, Zhang K, Zhang X, Yuan XH, Yuan Z, Jin L, et al. Comparison of gene expression between metastatic derivatives and their poorly metastatic parental cells implicates crucial tumor-environment interaction in metastasis of head and neck squamous cell carcinoma. Clin Exp Metastasis 2003;20:335-342
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 335-342
-
-
Chen, Z.1
Zhang, K.2
Zhang, X.3
Yuan, X.H.4
Yuan, Z.5
Jin, L.6
-
25
-
-
33749035470
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting
-
Sok JC, Coppelli FM, Thomas SM, Lango MN, Xi S, Hunt JL, et al. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res 2006;12:5064-5073
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5064-5073
-
-
Sok, J.C.1
Coppelli, F.M.2
Thomas, S.M.3
Lango, M.N.4
Xi, S.5
Hunt, J.L.6
-
26
-
-
0035834663
-
Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 coreceptor
-
Hellyer NJ, Kim MS, Koland JG. Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 coreceptor. J Biol Chem 2001;276:42153-42161
-
(2001)
J Biol Chem
, vol.276
, pp. 42153-42161
-
-
Hellyer, N.J.1
Kim, M.S.2
Koland, J.G.3
-
27
-
-
0026793914
-
Oral cancer progression and c-erbB-2/neu proto-oncogene expression
-
Hou L, Shi D, Tu SM, Zhang HZ, Hung MC, Ling D. Oral cancer progression and c-erbB-2/neu proto-oncogene expression. Cancer Lett 1992;65:215-220
-
(1992)
Cancer Lett
, vol.65
, pp. 215-220
-
-
Hou, L.1
Shi, D.2
Tu, S.M.3
Zhang, H.Z.4
Hung, M.C.5
Ling, D.6
-
28
-
-
0034782219
-
Colocalization of multiple ErbB receptors in stratifi ed epithelium of oral squamous cell carcinoma
-
Bei R, Pompa G, Vitolo D, Moriconi E, Ciocci L, Quaranta M. Colocalization of multiple ErbB receptors in stratifi ed epithelium of oral squamous cell carcinoma. J Pathol 2001;195:343-348
-
(2001)
J Pathol
, vol.195
, pp. 343-348
-
-
Bei, R.1
Pompa, G.2
Vitolo, D.3
Moriconi, E.4
Ciocci, L.5
Quaranta, M.6
-
29
-
-
0033372557
-
Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members
-
Xia W, Lau YK, Zhang HZ, Xiao FY, Johnston DA, Liu AR. Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin Cancer Res 1999;5:4164-4174
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4164-4174
-
-
Xia, W.1
Lau, Y.K.2
Zhang, H.Z.3
Xiao, F.Y.4
Johnston, D.A.5
Liu, A.R.6
-
30
-
-
0037710530
-
Epidermal growth factor receptor family tyrosine kinases as signal integrators and therapeutic targets
-
Barnes CJ, Kumar R. Epidermal growth factor receptor family tyrosine kinases as signal integrators and therapeutic targets. Cancer Metastasis Rev 2003;22:301-307
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 301-307
-
-
Barnes, C.J.1
Kumar, R.2
-
31
-
-
0034084314
-
Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
-
Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000;6:2166-2174
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2166-2174
-
-
Huang, S.M.1
Harari, P.M.2
-
32
-
-
0035254521
-
Head and neck cancer as a clinical model for molecular targeting of therapy: Combining EGFR blockade with radiation
-
Harari PM, Huang SM. Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation. Int J Radiat Oncol Biol Phys 2001;49:427-433
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 427-433
-
-
Harari, P.M.1
Huang, S.M.2
-
33
-
-
0035409904
-
IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
-
Herbst RS, Kim ES, Harari PM. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer. Expert Opin Biol Ther 2001;1:719-732
-
(2001)
Expert Opin Biol Ther
, vol.1
, pp. 719-732
-
-
Herbst, R.S.1
Kim, E.S.2
Harari, P.M.3
-
34
-
-
0036561431
-
Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade
-
Huang SM, Li J, Harari PM. Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade. Mol Cancer Ther 2002;1:507-514
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 507-514
-
-
Huang, S.M.1
Li, J.2
Harari, P.M.3
-
35
-
-
19244366949
-
Phase i studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
Baselga J, Pfi ster D, Cooper MR, Cohen R, Burtness B, Bos M, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000;18:904-914
-
(2000)
J Clin Oncol
, vol.18
, pp. 904-914
-
-
Baselga, J.1
Pfi Ster, D.2
Cooper, M.R.3
Cohen, R.4
Burtness, B.5
Bos, M.6
-
36
-
-
0034895886
-
Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer
-
Shin DM, Donato NJ, Perez-Soler R, Shin HJ, Wu JY, Zhang P, et al. Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer. Clin Cancer Res 2001;7:1204-1213
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1204-1213
-
-
Shin, D.M.1
Donato, N.J.2
Perez-Soler, R.3
Shin, H.J.4
Wu, J.Y.5
Zhang, P.6
-
37
-
-
0035398021
-
Phase i study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
-
Robert F, Ezekiel MP, Spencer SA, Meredith RF, Bonner JA, Khazaeli MB, et al. Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J Clin Oncol 2001;19:3234-3243
-
(2001)
J Clin Oncol
, vol.19
, pp. 3234-3243
-
-
Robert, F.1
Ezekiel, M.P.2
Spencer, S.A.3
Meredith, R.F.4
Bonner, J.A.5
Khazaeli, M.B.6
-
38
-
-
24944490558
-
Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck
-
Herbst RS, Arquette M, Shin DM, Dicke K, Vokes EE, Azarnia N, et al. Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck. J Clin Oncol 2005;23:5578-5587
-
(2005)
J Clin Oncol
, vol.23
, pp. 5578-5587
-
-
Herbst, R.S.1
Arquette, M.2
Shin, D.M.3
Dicke, K.4
Vokes, E.E.5
Azarnia, N.6
-
39
-
-
23844523253
-
Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck
-
Baselga J, Trigo JM, Bourhis J, Tortochaux J, Cortés-Funes H, Hitt R, et al. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2005;23:5568-5577
-
(2005)
J Clin Oncol
, vol.23
, pp. 5568-5577
-
-
Baselga, J.1
Trigo, J.M.2
Bourhis, J.3
Tortochaux, J.4
Cortés-Funes, H.5
Hitt, R.6
-
40
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354:567-578
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
-
41
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, Remenar E, Kawecki A, Rottey S, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008;359:1116-1127
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
Remenar, E.4
Kawecki, A.5
Rottey, S.6
-
42
-
-
33746862936
-
Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer
-
Heymach JV, Nilsson M, Blumenschein G, Papadimitrakopoulou V, Herbst R. Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer. Clin Cancer Res 2006;12:4441s-5s.
-
(2006)
Clin Cancer Res
, vol.12
-
-
Heymach, J.V.1
Nilsson, M.2
Blumenschein, G.3
Papadimitrakopoulou, V.4
Herbst, R.5
-
43
-
-
45349097237
-
Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer
-
Wu M, Rivkin A, Pham T. Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer. Clin Ther 2008;30:14-30.
-
(2008)
Clin Ther
, vol.30
, pp. 14-30
-
-
Wu, M.1
Rivkin, A.2
Pham, T.3
-
44
-
-
51449117743
-
Augmentation of radiation response by panitumumab in models of upper aerodigestive tract cancer
-
Kruser TJ, Armstrong EA, Ghia AJ, Huang S, Wheeler DL, Radinsky R, et al. Augmentation of radiation response by panitumumab in models of upper aerodigestive tract cancer. Int J Radiat Oncol Biol Phys 2008;72:534-542
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.72
, pp. 534-542
-
-
Kruser, T.J.1
Armstrong, E.A.2
Ghia, A.J.3
Huang, S.4
Wheeler, D.L.5
Radinsky, R.6
-
45
-
-
0033763084
-
ZD1839 ('Iressa') as an anticancer agent
-
Baselga J, Averbuch SD. ZD1839 ('Iressa') as an anticancer agent. Drugs 2000;60:33-40.
-
(2000)
Drugs
, vol.60
, pp. 33-40
-
-
Baselga, J.1
Averbuch, S.D.2
-
46
-
-
0034489914
-
Effi cacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
-
Sirotnak FM, Zakowski MF, Miller VA, Scher HI, Kris MG. Effi cacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 2000;6:4885-4892
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4885-4892
-
-
Sirotnak, F.M.1
Zakowski, M.F.2
Miller, V.A.3
Scher, H.I.4
Kris, M.G.5
-
48
-
-
0036842170
-
Phase i safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with fi ve selected solid tumor types
-
Baselga J, Rischin D, Ranson M, Calvert H, Raymond E, Kieback DG, et al.Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with fi ve selected solid tumor types. J Clin Oncol 2002;20:4292-4302
-
(2002)
J Clin Oncol
, vol.20
, pp. 4292-4302
-
-
Baselga, J.1
Rischin, D.2
Ranson, M.3
Calvert, H.4
Raymond, E.5
Kieback, D.G.6
-
49
-
-
0036569870
-
ZD1839, a selective oral epidermal growth factor receptortyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase i trial
-
Ranson M, Hammond LA, Ferry D, Kris M, Tullo A, Murray PI, et al. ZD1839, a selective oral epidermal growth factor receptortyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial. J Clin Oncol 2002;20:2240-2250
-
(2002)
J Clin Oncol
, vol.20
, pp. 2240-2250
-
-
Ranson, M.1
Hammond, L.A.2
Ferry, D.3
Kris, M.4
Tullo, A.5
Murray, P.I.6
-
50
-
-
0037106377
-
Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase i trial
-
Herbst RS, Maddox AM, Rothenberg ML, Small EJ, Rubin EH, Baselga J, et al. Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J Clin Oncol 2002;20:3815-3825
-
(2002)
J Clin Oncol
, vol.20
, pp. 3815-3825
-
-
Herbst, R.S.1
Maddox, A.M.2
Rothenberg, M.L.3
Small, E.J.4
Rubin, E.H.5
Baselga, J.6
-
51
-
-
0037673681
-
Phase i pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefi tinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors
-
Nakagawa K, Tamura T, Negoro S, Kudoh S, Yamamoto N, Yamamoto N, et al. Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefi tinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors. Ann Oncol 2003;14:922-930
-
(2003)
Ann Oncol
, vol.14
, pp. 922-930
-
-
Nakagawa, K.1
Tamura, T.2
Negoro, S.3
Kudoh, S.4
Yamamoto, N.5
Yamamoto, N.6
-
52
-
-
0038276045
-
Improvements in quality of life and disease-related symptoms in phase i trials of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in non-small cell lung cancer and other solid tumors
-
LoRusso PM, Herbst RS, Rischin D, Ranson M, Calvert H, Raymond E, et al. Improvements in quality of life and disease-related symptoms in phase I trials of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in non-small cell lung cancer and other solid tumors. Clin Cancer Res 2003;9:2040-2048
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2040-2048
-
-
Lo Russo, P.M.1
Herbst, R.S.2
Rischin, D.3
Ranson, M.4
Calvert, H.5
Raymond, E.6
-
53
-
-
0037674062
-
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
-
Cohen EE, Rosen F, Stadler WM, Recant W, Stenson K, Huo D, et al. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003;21:1980-1987
-
(2003)
J Clin Oncol
, vol.21
, pp. 1980-1987
-
-
Cohen, E.E.1
Rosen, F.2
Stadler, W.M.3
Recant, W.4
Stenson, K.5
Huo, D.6
-
54
-
-
28544432807
-
Phase II trial of gefi tinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
-
Cohen EE, Kane MA, List MA, Brockstein BE, Mehrotra B, Huo D, et al. Phase II trial of gefi tinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. Clin Cancer Res 2005;11:8418-8424
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8418-8424
-
-
Cohen, E.E.1
Man, K.2
Man, L.3
Brockstein, B.E.4
Mehrotra, B.5
Huo, D.6
-
55
-
-
33644842102
-
Gefi tinib (ZD1839, Iressa) as palliative treatment in recurrent or metastatic head and neck cancer
-
Kirby AM, A'Hern RP, D'Ambrosio C, Tanay M, Syrigos KN, Rogers SJ, et al. Gefi tinib (ZD1839, Iressa) as palliative treatment in recurrent or metastatic head and neck cancer. Br J Cancer 2006;94:631-636
-
(2006)
Br J Cancer
, vol.94
, pp. 631-636
-
-
Kirby, A.M.1
A'Hern, R.P.2
D'Ambrosio, C.3
Tanay, M.4
Syrigos, K.N.5
Rogers, S.J.6
-
56
-
-
0037068741
-
Antitumor activity of GW572016: A dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways
-
Xia W, Mullin RJ, Keith BR, Liu LH, Ma H, Rusnak DW, et al. Antitumor activity of GW572016: A dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways. Oncogene 2002;21:6255-6263
-
(2002)
Oncogene
, vol.21
, pp. 6255-6263
-
-
Xia, W.1
Mullin, R.J.2
Keith, B.R.3
Liu, L.H.4
Man, H.5
Rusnak, D.W.6
-
57
-
-
23944476155
-
Phase i safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
-
Burris HA 3rd, Hurwitz HI, Dees EC, Dowlati A, Blackwell KL, O'Neil B, et al. Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol 2005;23:5305-5313
-
(2005)
J Clin Oncol
, vol.23
, pp. 5305-5313
-
-
Burris III, H.A.1
Hurwitz, H.I.2
Dees, E.C.3
Dowlati, A.4
Blackwell, K.L.5
O'Neil, B.6
-
58
-
-
77954436168
-
Effect of lapatinib on apoptosis and proliferation: Results of a phase II randomised study in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN)
-
(abstract 688O)
-
Del Campo JM, Sebastian P, Hitt R, Carracedo C, Lokanatha D, Bourhis J, et al. Effect of lapatinib on apoptosis and proliferation: Results of a phase II randomised study in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Ann Oncol 2008;19; viii217 (abstract 688O).
-
(2008)
Ann Oncol
, vol.19
-
-
Del Campo, J.M.1
Sebastian, P.2
Hitt, R.3
Carracedo, C.4
Lokanatha, D.5
Bourhis, J.6
-
59
-
-
77954432862
-
A phase i study to establish the recommended phase II dose of lapatinib in combination with chemoradiation in patients with locally advanced squamous cell carcinoma of the head and neck
-
(in press)
-
Harrington KJ, El-Hariry IA, Holford CS, Lusinchi A, Nutting CM, Rosine D, et al. A phase I study to establish the recommended phase II dose of lapatinib in combination with chemoradiation in patients with locally advanced squamous cell carcinoma of the head and neck. J Clin Oncol (in press).
-
J Clin Oncol
-
-
Harrington, K.J.1
El-Hariry, I.A.2
Holford, C.S.3
Lusinchi, A.4
Nutting, C.M.5
Rosine, D.6
-
60
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med 2006;57:1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
61
-
-
44649197646
-
Targeting angiogenesis in head and neck cancer
-
Seiwert TY, Cohen EE. Targeting angiogenesis in head and neck cancer. Semin Oncol 2008;35:274-285
-
(2008)
Semin Oncol
, vol.35
, pp. 274-285
-
-
Seiwert, T.Y.1
Cohen, E.E.2
-
62
-
-
33845286942
-
Vascular disrupting agents
-
Lippert JW 3rd. Vascular disrupting agents. Bioorg Med Chem. 2007;15:605-615
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 605-615
-
-
Lippert III, J.W.1
-
63
-
-
0027497564
-
In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum caffrum (arid shrub)
-
el-Zayat AA, Degen D, Drabek S, Clark GM, Pettit GR, Von Hoff DD. In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum caffrum (arid shrub). Anticancer Drugs 1993;4:19-25.
-
(1993)
Anticancer Drugs
, vol.4
, pp. 19-25
-
-
El-Zayat, A.A.1
Degen, D.2
Drabek, S.3
Clark, G.M.4
Pettit, G.R.5
Von Hoff, D.D.6
-
64
-
-
0029902597
-
Antivascular approaches to solid tumour therapy: Evaluation of tubulin binding agents
-
Chaplin DJ, Pettit GR, Parkins CS, Hill SA. Antivascular approaches to solid tumour therapy: Evaluation of tubulin binding agents. Br J Cancer Suppl 1996;27:S86-8.
-
(1996)
Br J Cancer Suppl
, vol.27
-
-
Chaplin, D.J.1
Pettit, G.R.2
Parkins, C.S.3
Hill, S.A.4
-
65
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain RK. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 2005;307:58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
66
-
-
35748970483
-
Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
-
Fukumura D, Jain RK. Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization. Microvasc Res 2007;74:72-84.
-
(2007)
Microvasc Res
, vol.74
, pp. 72-84
-
-
Fukumura, D.1
Jain, R.K.2
-
67
-
-
49049086338
-
Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
-
Ashkenazi A, Holland P, Eckhardt SG. Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J Clin Oncol 2008;26:3621-3630
-
(2008)
J Clin Oncol
, vol.26
, pp. 3621-3630
-
-
Ashkenazi, A.1
Holland, P.2
Eckhardt, S.G.3
-
69
-
-
28144459799
-
Combination bcl-2 antisense and radiation therapy for nasopharyngeal cancer
-
Yip KW, Mocanu JD, Au PY, Sleep GT, Huang D, Busson P, et al.Combination bcl-2 antisense and radiation therapy for nasopharyngeal cancer. Clin Cancer Res 2005;11:8131-8144
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8131-8144
-
-
Yip, K.W.1
Mocanu, J.D.2
Au, P.Y.3
Sleep, G.T.4
Huang, D.5
Busson, P.6
-
70
-
-
33745222843
-
Systemic Bcl-2 antisense oligodeoxynucleotide in combination with cisplatin cures EBV+ nasopharyngeal carcinoma xenografts in SCID mice
-
Lacy J, Loomis R, Grill S, Srimatkandada P, Carbone R, Cheng YC. Systemic Bcl-2 antisense oligodeoxynucleotide in combination with cisplatin cures EBV+ nasopharyngeal carcinoma xenografts in SCID mice. Int J Cancer 2006;119:309-316
-
(2006)
Int J Cancer
, vol.119
, pp. 309-316
-
-
Lacy, J.1
Loomis, R.2
Grill, S.3
Srimatkandada, P.4
Carbone, R.5
Cheng, Y.C.6
-
72
-
-
0036653127
-
Cyclindependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells
-
Mihara M, Shintani S, Kiyota A, Matsumura T, Wong DT. Cyclindependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells. Int J Oncol 2002;21:95-101.
-
(2002)
Int J Oncol
, vol.21
, pp. 95-101
-
-
Mihara, M.1
Shintani, S.2
Kiyota, A.3
Matsumura, T.4
Wong, D.T.5
-
73
-
-
33846254185
-
A phase i trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days
-
Benson C, White J, De Bono J, O'Donnell A, Raynaud F, Cruickshank C, et al. A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days. Br J Cancer 2007;96:29-37.
-
(2007)
Br J Cancer
, vol.96
, pp. 29-37
-
-
Benson, C.1
White, J.2
De Bono, J.3
O'Donnell, A.4
Raynaud, F.5
Cruickshank, C.6
-
74
-
-
7944233068
-
Head and neck chapter in treatment of cancer
-
Price P Sikora K. editors Edition 1.. Chapman and Hall Medical London UK
-
Munro AJ, MacDougall RH, Stafford ND. Head and Neck Chapter in Treatment of Cancer. In: Price P, Sikora K. editors. Treatment of Cancer Edition 1.. Chapman and Hall Medical, London UK:; 2002. p. 313-390
-
(2002)
Treatment of Cancer
, pp. 313-390
-
-
Munro, A.J.1
MacDougall, R.H.2
Stafford, N.D.3
-
75
-
-
0027216010
-
Diagnosis and management of squamous cell carcinoma of unknown primary tumor site of the neck
-
De Braud F, al-Sarraf M. Diagnosis and management of squamous cell carcinoma of unknown primary tumor site of the neck. Semin Oncol 1993;20:273-278
-
(1993)
Semin Oncol
, vol.20
, pp. 273-278
-
-
De Braud, F.1
Al-Sarraf, M.2
-
76
-
-
17244382652
-
The infl uence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx, and hypopharynx: N0 versus N+
-
Layland MK, Sessions DG, Lenox J. The infl uence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx, and hypopharynx: N0 versus N+. Laryngoscope 2005;115:629-639
-
(2005)
Laryngoscope
, vol.115
, pp. 629-639
-
-
Layland, M.K.1
Sessions, D.G.2
Lenox, J.3
-
77
-
-
0034080318
-
The biology of chemokines and their receptors
-
Rossi D, Zlotnik A. The biology of chemokines and their receptors. Annu Rev Immunol 2000;18:217-242
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 217-242
-
-
Rossi, D.1
Zlotnik, A.2
-
79
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Müller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Müller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
-
80
-
-
34548295350
-
Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival
-
Pitkin L, Luangdilok S, Corbishley C, Wilson PO, Dalton P, Bray D, et al. Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival Br J Cancer 2007;97:670-677
-
(2007)
Br J Cancer
, vol.97
, pp. 670-677
-
-
Pitkin, L.1
Luangdilok, S.2
Corbishley, C.3
Wilson, P.O.4
Dalton, P.5
Bray, D.6
-
81
-
-
41749086697
-
Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: Implications for therapy
-
Wang J, Seethala RR, Zhang Q, Gooding W, van Waes C, Hasegawa H, et al. Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: Implications for therapy. J Natl Cancer Inst 2008;100:502-512
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 502-512
-
-
Wang, J.1
Seethala, R.R.2
Zhang, Q.3
Gooding, W.4
Van Waes, C.5
Hasegawa, H.6
-
82
-
-
3042616145
-
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
-
Liang Z, Wu T, Lou H, Yu X, Taichman RS, Lau SK, et al. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res 2004;64:4302-4308
-
(2004)
Cancer Res
, vol.64
, pp. 4302-4308
-
-
Liang, Z.1
Wu, T.2
Lou, H.3
Yu, X.4
Taichman, R.S.5
Lau, S.K.6
|