Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus

European Journal of Neuroscience

Volumn 32, Issue 1, 2010, Pages 80-88

  Nagarkatti, Nisha ^a   Deshpande, Laxmikant S ^b   Carter, Dawn S ^b   Delorenzo, Robert J ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

calcium dynamics; cultured hippocampal neurons; epileptogenesis; Fura 2; patch clamp electrophysiology; rat

Indexed keywords

CALCIUM; DANTROLENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; EPILEPTIC DISCHARGE; EPILEPTIC STATE; EPILEPTOGENESIS; HIPPOCAMPUS; IN VITRO STUDY; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CELL DEATH; CELLS, CULTURED; DANTROLENE; DIZOCILPINE MALEATE; EPILEPSY; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; MUSCARINIC AGONISTS; MUSCLE RELAXANTS, CENTRAL; NEURONS; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 77954413689     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2010.07262.x     Document Type: Article

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