Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons

Epilepsia

Volumn 49, Issue 10, 2008, Pages 1795-1802

  Deshpande, Laxmikant S ^a   Nagarkatti, Nisha ^b   Ziobro, Julie M ^b   Sombati, Sompong ^a   Delorenzo, Robert J ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Carisbamate; Epilepsy; Neuronal cultures; Neuroprotection

Indexed keywords

ANTICONVULSIVE AGENT; CARISBAMATE; MAGNESIUM; UNCLASSIFIED DRUG; CARBAMIC ACID DERIVATIVE; PHENOBARBITAL; S 2 O CARBAMOYL 1 O CHLOROPHENYL ETHANOL; S-2-O-CARBAMOYL-1-O-CHLOROPHENYL-ETHANOL;

ARTICLE; BRAIN INJURY; CONTROLLED STUDY; EPILEPTIC DISCHARGE; EPILEPTIC STATE; NERVE CELL CULTURE; NERVE CELL NETWORK; NEUROPROTECTION; PRIORITY JOURNAL; ACTION POTENTIAL; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG EFFECT; EPILEPSY; HIPPOCAMPUS; METHODOLOGY; NERVE CELL; NEWBORN; PATCH CLAMP; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTICONVULSANTS; CARBAMATES; CELL DEATH; CELLS, CULTURED; EPILEPSY; HIPPOCAMPUS; MAGNESIUM; NEURONS; PATCH-CLAMP TECHNIQUES; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 58149241018     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.01667.x     Document Type: Article

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