-
2
-
-
2142853538
-
Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma
-
Beck SD, Patel MI, Snyder ME et al. Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma. Ann Surg Oncol 2004; 11: 71-77.
-
(2004)
Ann Surg Oncol
, vol.11
, pp. 71-77
-
-
Beck, S.D.1
Patel, M.I.2
Snyder, M.E.3
-
3
-
-
0037407573
-
Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
-
DOI 10.1097/00000478-200305000-00005
-
Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Path 2003; 27: 612-624. (Pubitemid 36514472)
-
(2003)
American Journal of Surgical Pathology
, vol.27
, Issue.5
, pp. 612-624
-
-
Cheville, J.C.1
Lohse, C.M.2
Zincke, H.3
Weaver, A.L.4
Blute, M.L.5
-
4
-
-
53849131709
-
Renal cell carcinoma with rhabdoid features. Divergent differentiation of conventional (clear cell) carcinoma
-
Klimis T, Karvounis H. Renal cell carcinoma with rhabdoid features. Divergent differentiation of conventional (clear cell) carcinoma. J BUON 2008; 13: 433-436.
-
(2008)
J BUON
, vol.13
, pp. 433-436
-
-
Klimis, T.1
Karvounis, H.2
-
5
-
-
0032772880
-
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
-
Motzer RJ, Mazumadar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol 1999; 17: 2530-2540. (Pubitemid 29368255)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2530-2540
-
-
Motzer, R.J.1
Mazumdar, M.2
Bacik, J.3
Berg, W.4
Amsterdam, A.5
Ferrara, J.6
-
6
-
-
35148857486
-
Sunitinib Efficacy Against Advanced Renal Cell Carcinoma
-
DOI 10.1016/j.juro.2007.07.030, PII S0022534707017661
-
Motzer RJ, Michaelson MD, Rosenberg J et al. Sunitinib efficacy against advanced renal cell carcinoma. J Urol 2007; 178: 1883-1887. (Pubitemid 47538608)
-
(2007)
Journal of Urology
, vol.178
, Issue.5
, pp. 1883-1887
-
-
Motzer, R.J.1
Michaelson, M.D.2
Rosenberg, J.3
Bukowski, R.M.4
Curti, B.D.5
George, D.J.6
Hudes, G.R.7
Redman, B.G.8
Margolin, K.A.9
Wilding, G.10
-
7
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 1993; 260: 1317-1320. (Pubitemid 23231974)
-
(1993)
Science
, vol.260
, Issue.5112
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
Yao, M.4
Duh, F.-M.5
Orcutt, M.L.6
Stackhouse, T.7
Kuzmin, I.8
Modi, W.9
Geil, L.10
Schmidt, L.11
Zhou, F.12
Li, H.13
Ming Hui, W.14
Chen, F.15
Glenn, G.16
Choyke, P.17
Walther, M.M.18
Weng, Y.19
-
8
-
-
0042342564
-
The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer
-
DOI 10.1056/NEJMp030061
-
George DJ, Kaelin WG Jr. The von Hippel-Lindau protein, vascular endothelial growth factor and kidney cancer. N Engl J Med 2003; 349: 419-421. (Pubitemid 36910018)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 419-421
-
-
George, D.J.1
Kaelin Jr., W.G.2
-
9
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N, Kerbel R. Angiogenesis as a therapeutic target. Nature 2005; 438: 967-974.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.2
-
11
-
-
0030786569
-
Tumor-infiltrating dendritic cells are defective in their antigen- Presenting function and inducible B7 expression in rats
-
DOI 10.1002/(SICI)1097-0215(19970807)72:4<619::AID-IJC12>3.0.CO;2-6
-
Chaux P, Moutet M, Martin M, Martin F. Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. Int J Cancer 1997; 72: 619-624. (Pubitemid 27356163)
-
(1997)
International Journal of Cancer
, vol.72
, Issue.4
, pp. 619-624
-
-
Chaux, P.1
Favre, N.2
Martin, M.3
Martin, F.4
-
12
-
-
0029997017
-
Dendritic cells in antitumor immune responses I. Defective antigen presentation in tumor-bearing hosts
-
Gabrilovich DI, Ciemik IF, Carbone DP. Dendritic cells in antitumor immune responses I. Defective antigen presentation in tumor-bearing hosts. Cell Immunol 1996; 170: 101-110.
-
(1996)
Cell Immunol
, vol.170
, pp. 101-110
-
-
Gabrilovich, D.I.1
Ciemik, I.F.2
Carbone, D.P.3
-
13
-
-
0033568001
-
Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo
-
Ohm JE, Shurin MR, Esche C et al. Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo. J Immunol 1999; 163: 3260-3268. (Pubitemid 29431827)
-
(1999)
Journal of Immunology
, vol.163
, Issue.6
, pp. 3260-3268
-
-
Ohm, J.E.1
Shurin, M.R.2
Esche, C.3
Lotze, M.T.4
Carbone, D.P.5
Gabrilovich, D.I.6
-
14
-
-
0029842830
-
Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
-
DOI 10.1038/nm1096-1096
-
Gabrilovich DI, Chen HL, Girgis KR et al. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 1996; 2: 1096-1103. (Pubitemid 26338628)
-
(1996)
Nature Medicine
, vol.2
, Issue.10
, pp. 1096-1103
-
-
Gabrilovich, D.I.1
Chen, H.L.2
Girgis, K.R.3
Cunningham, H.T.4
Meny, G.M.5
Nadaf, S.6
Kavanaugh, D.7
Carbone, D.P.8
-
15
-
-
2542470851
-
Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines
-
DOI 10.1007/s00262-003-0466-8
-
Takahashi A, Kono K, Ichihara F et al. Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines. Cancer Immunol Immunother 2004; 53: 543-550. (Pubitemid 38680261)
-
(2004)
Cancer Immunology, Immunotherapy
, vol.53
, Issue.6
, pp. 543-550
-
-
Takahashi, A.1
Kono, K.2
Ichihara, F.3
Sugai, H.4
Fujii, H.5
Matsumoto, Y.6
-
16
-
-
10844238910
-
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation
-
Dikov MM, Ohm JE, Ray N et al. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J Immunol 2005; 174: 215-222. (Pubitemid 40007407)
-
(2005)
Journal of Immunology
, vol.174
, Issue.1
, pp. 215-222
-
-
Dikov, M.M.1
Ohm, J.E.2
Ray, N.3
Tchekneva, E.E.4
Burlison, J.5
Moghanaki, D.6
Nadaf, S.7
Carbone, D.P.8
-
17
-
-
34548125294
-
Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
-
DOI 10.1158/1078-0432.CCR-07-0409
-
Fricke I, Mirza N, Dupont J et al. Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin Cancer Res 2007; 13: 4840-4848. (Pubitemid 47298146)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.16
, pp. 4840-4848
-
-
Fricke, I.1
Mirza, N.2
Dupont, J.3
Lockhart, C.4
Jackson, A.5
Lee, J.-H.6
Sosman, J.A.7
Gabrilovich, D.I.8
-
18
-
-
0037777538
-
VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression
-
Ohm JE, Gabrilovich DI, Sempowski GD et al. VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression. Blood 2003; 101: 4878-4886.
-
(2003)
Blood
, vol.101
, pp. 4878-4886
-
-
Ohm, J.E.1
Gabrilovich, D.I.2
Sempowski, G.D.3
-
19
-
-
7144227930
-
Recombinant human IL-2, recombinant human interferon alpha-2a, or both in metastatic renal-cell carcinoma
-
Groupe Francais d'Immunotherapie
-
Negrier S, Escudier B, Lasset C et al. Recombinant human IL-2, recombinant human interferon alpha-2a, or both in metastatic renal-cell carcinoma. Groupe Francais d'Immunotherapie. N Engl J Med 1998; 338: 1272-1278.
-
(1998)
N Engl J Med
, vol.338
, pp. 1272-1278
-
-
Negrier, S.1
Escudier, B.2
Lasset, C.3
-
20
-
-
0033978220
-
Systemic therapy for renal cell carcinoma
-
Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J Urol 2000; 163: 408-417. (Pubitemid 30060482)
-
(2000)
Journal of Urology
, vol.163
, Issue.2
, pp. 408-417
-
-
Motzer, R.J.1
Russo, P.2
-
21
-
-
36448930484
-
Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: Results of a randomized controlled trial
-
DOI 10.1002/cncr.23056
-
Negrier S, Perol D, Ravaud A et al. Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: results of a randomized controlled trial. Cancer 2007; 110: 2468-2477. (Pubitemid 350174932)
-
(2007)
Cancer
, vol.110
, Issue.11
, pp. 2468-2477
-
-
Negrier, S.1
Perol, D.2
Ravaud, A.3
Chevreau, C.4
Bay, J.-O.5
Delva, R.6
Sevin, E.7
Caty, A.8
Escudier, B.9
-
22
-
-
36749016244
-
Sunitinib, sorafenib and mTOR inhibitors in renal cancer
-
Radulovic S, Bjelogrlic SK. Sunitinib, sorafenib and mTOR inhibitors in renal cancer. J BUON 2007; 12(Suppl 1): S151-S162.
-
(2007)
J BUON
, vol.12
, Issue.SUPPL. 1
-
-
Radulovic, S.1
Bjelogrlic, S.K.2
-
23
-
-
33744954585
-
Sunitinib in patient swim metastatic renal cell carcinoma
-
Motzer RJ, Rini BI, Bukowski RM et al. Sunitinib in patient swim metastatic renal cell carcinoma. JAMA 2006; 295: 2516-2524.
-
(2006)
JAMA
, vol.295
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
-
24
-
-
33846181370
-
Sunitinib versus interferon alpha in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczack P et al. Sunitinib versus interferon alpha in metastatic renal-cell carcinoma. N Engl J Med 2007; 356: 115-124.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczack, P.3
-
25
-
-
63849092341
-
Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: Clinical outcomes and plasma angiogenesis markers
-
Kontovinis LF, Papazisis KT, Touplikioti P et al. Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. BMC Cancer 2009; 9: 82.
-
(2009)
BMC Cancer
, vol.9
, pp. 82
-
-
Kontovinis, L.F.1
Papazisis, K.T.2
Touplikioti, P.3
-
26
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007; 356: 115-134.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
27
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier B, Pluzanska A, Koralewski P et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007; 370: 2103-2111. (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
28
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007; 356: 2271-2281. (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
29
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomized, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomized, placebo-controlled phase III trial. Lancet 2008; 372: 449-456.
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
30
-
-
0032741283
-
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
-
Gabrilovich DI, Ishida T, Nadaf S et al. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res 1999; 5: 2963-2970. (Pubitemid 29493976)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.10
, pp. 2963-2970
-
-
Gabrilovich, D.I.1
Ishida, T.2
Nadaf, S.3
Ohm, J.E.4
Carbone, D.P.5
-
31
-
-
28344453449
-
Interferon-alpha2a is sufficient for promoting dendritic cell immunogenicity
-
DOI 10.1111/j.1365-2249.2005.02933.x
-
Tamir A, Jordan WJ, Ritter M et al. Interferon-alpha2a is sufficient for promoting dendritic cell immunogenicity. Clin Exp Immunol 2005; 142: 471-480. (Pubitemid 41719843)
-
(2005)
Clinical and Experimental Immunology
, vol.142
, Issue.3
, pp. 471-480
-
-
Tamir, A.1
Jordan, W.J.2
Ritter, M.3
Habib, N.4
Lechler, R.I.5
Foster, G.R.6
Lombardi, G.7
-
32
-
-
48749092867
-
First-line bevacizumab combined with reduced dose interferon-alpha2a is active in patients with metastatic renal cell carcinoma
-
Melichar B, Koralewski P, Ravaud A et al. First-line bevacizumab combined with reduced dose interferon-alpha2a is active in patients with metastatic renal cell carcinoma. Ann Oncol 2008; 19: 1470-1476.
-
(2008)
Ann Oncol
, vol.19
, pp. 1470-1476
-
-
Melichar, B.1
Koralewski, P.2
Ravaud, A.3
-
33
-
-
52549127241
-
Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3) K-mTOR-p70S6K pathway
-
Cao W, Manicassamy S, Tang H et al. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3) K-mTOR-p70S6K pathway. Nat Immunol 2008; 9: 1157-1164.
-
(2008)
Nat Immunol
, vol.9
, pp. 1157-1164
-
-
Cao, W.1
Manicassamy, S.2
Tang, H.3
-
34
-
-
56049092542
-
Dendritic cell derived IL-18 production is inhibited by rapamycin and sanglifehrin A, but not cyclosporine a
-
Ko H, Hambly BD, Eris JM et al. Dendritic cell derived IL-18 production is inhibited by rapamycin and sanglifehrin A, but not cyclosporine A. Transpl Immunol 2008; 20: 99-105.
-
(2008)
Transpl Immunol
, vol.20
, pp. 99-105
-
-
Ko, H.1
Hambly, B.D.2
Eris, J.M.3
-
35
-
-
0037441902
-
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression
-
WoltmanAM, van der Kooij SW, Coffer PJ et al. Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood 2003; 101: 1439-1445.
-
(2003)
Blood
, vol.101
, pp. 1439-1445
-
-
Woltman, A.M.1
Van Der Kooij, S.W.2
Coffer, P.J.3
-
36
-
-
50949130076
-
Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells
-
Ohtani M, Nagai S, Kondo S et al. Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. Blood 2008; 112: 635-643.
-
(2008)
Blood
, vol.112
, pp. 635-643
-
-
Ohtani, M.1
Nagai, S.2
Kondo, S.3
-
37
-
-
54949109311
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response
-
Weichhart T, Costantino G, Poglitsch M et al. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 2008; 29: 565-577.
-
(2008)
Immunity
, vol.29
, pp. 565-577
-
-
Weichhart, T.1
Costantino, G.2
Poglitsch, M.3
-
38
-
-
53249111806
-
Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival
-
Van Cruijsen H, van der Veldt AA, Vroling L etal. Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival. Clin Cancer Res 2008; 14: 5884-5892.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5884-5892
-
-
Van Cruijsen, H.1
Van Der Veldt, A.A.2
Vroling, L.3
-
39
-
-
77954405261
-
Immunologic effects of sunitinib in renal cell carcinoma
-
abstr
-
Lenahan C, Cho D, Bissonnette A et al. Immunologic effects of sunitinib in renal cell carcinoma. J Clin Oncol 2008; 26 (Suppl): 14551 (abstr).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
, pp. 14551
-
-
Lenahan, C.1
Cho, D.2
Bissonnette, A.3
-
40
-
-
58149179532
-
Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients
-
Finke J, Rini B, Ireland J, Rayman P et al. Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients. Clin Cancer Res 2008; 14: 6674-6682.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6674-6682
-
-
Finke, J.1
Rini, B.2
Ireland, J.3
Rayman, P.4
-
41
-
-
44249093051
-
The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients
-
Osada T, Chong G, Tansik R et al. The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients. Cancer Immunol Immunother 2008; 57: 1115-1124.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1115-1124
-
-
Osada, T.1
Chong, G.2
Tansik, R.3
-
42
-
-
0036401105
-
BAY 43-9006: Preclinical data
-
Wilhelm S, Chien DS. BAY 43-9006: preclinical data. Curr Pharm Des 2002; 8: 2255-2257.
-
(2002)
Curr Pharm des
, vol.8
, pp. 2255-2257
-
-
Wilhelm, S.1
Chien, D.S.2
-
43
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004; 64: 7099-7109.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
44
-
-
0028208969
-
Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes
-
Franklin RA, Tordai A, Patel H et al. Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes. J Clin Invest 1994; 93: 2134-2140.
-
(1994)
J Clin Invest
, vol.93
, pp. 2134-2140
-
-
Franklin, R.A.1
Tordai, A.2
Patel, H.3
-
45
-
-
45149084681
-
Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation
-
DOI 10.1038/leu.2008.58, PII LEU200858
-
Zhao W, Gu YH, Song R et al. Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation. Leukemia 2008; 22: 1226-1233. (Pubitemid 351833791)
-
(2008)
Leukemia
, vol.22
, Issue.6
, pp. 1226-1233
-
-
Zhao, W.1
Gu, Y.H.2
Song, R.3
Qu, B.Q.4
Xu, Q.5
-
46
-
-
47049127786
-
Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses
-
Hipp MM, Hiff N, Walter S et al. Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood 2008; 111: 5610-5620.
-
(2008)
Blood
, vol.111
, pp. 5610-5620
-
-
Hipp, M.M.1
Hiff, N.2
Walter, S.3
-
47
-
-
34447343347
-
Hypertension as a predictive factor of Sunitinib activity [1]
-
DOI 10.1093/annonc/mdm184
-
Rixe O, Billemont B, Izzedine H. Hypertension as apredictive factor of sunitinib activity. Ann Oncol 2007; 18: 1117. (Pubitemid 47050505)
-
(2007)
Annals of Oncology
, vol.18
, Issue.6
, pp. 1117
-
-
Rixe, O.1
Billemont, B.2
Izzedine, H.3
-
48
-
-
60849103018
-
Evaluation of thyroid dysfunction as a candidate surrogate marker for efficacy of sunitinib in patients (pts) with advanced renal cell carcinoma (RCC)
-
abstr
-
Wolter P, Stefan C, Decallonne B et al. Evaluation of thyroid dysfunction as a candidate surrogate marker for efficacy of sunitinib in patients (pts) with advanced renal cell carcinoma (RCC). J Clin Oncol 2008; 26 (Suppl): 5126 (abstr).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
, pp. 5126
-
-
Wolter, P.1
Stefan, C.2
Decallonne, B.3
-
49
-
-
77954419346
-
In vitro and in vivo analysis of synergistic antitumor effects of interferon-α and sorafenib in renal cell carcinoma
-
abstr
-
Eto M, Takeucbi A, Ohki T et al. In vitro and in vivo analysis of synergistic antitumor effects of interferon-α and sorafenib in renal cell carcinoma. J Clin Oncol 2008; 26 (Suppl): 16143 (abstr).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
, pp. 16143
-
-
Eto, M.1
Takeucbi, A.2
Ohki, T.3
-
50
-
-
57449084262
-
A randomized phase II trial of sorafenib versus sorafenib plus low-dose interferon-alfa: Clinical results and biomarker analysis
-
abstr
-
Tannik NM, Zurita AJ, Heymach JV et al. A randomized phase II trial of sorafenib versus sorafenib plus low-dose interferon-alfa: Clinical results and biomarker analysis. J Clin Oncol 2008; 26(Suppl): 5093 (abstr).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
, pp. 5093
-
-
Tannik, N.M.1
Zurita, A.J.2
Heymach, J.V.3
-
51
-
-
67650327598
-
Metastatic renal cell carcinoma: Many treatment options, one patient
-
Rini BI. Metastatic renal cell carcinoma: many treatment options, one patient. J Clin Oncol 2009; 27: 3225-3234.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3225-3234
-
-
Rini, B.I.1
-
52
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
Fyge G, Fisher RI, Rosenberg SA et al. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 1995; 13: 688-696.
-
(1995)
J Clin Oncol
, vol.13
, pp. 688-696
-
-
Fyge, G.1
Fisher, R.I.2
Rosenberg, S.A.3
-
53
-
-
48249117436
-
High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma: A retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006
-
Klapper JA, Downey SG, Smith FO et al. High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma: a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006. Cancer 2008; 113: 293-301.
-
(2008)
Cancer
, vol.113
, pp. 293-301
-
-
Klapper, J.A.1
Downey, S.G.2
Smith, F.O.3
-
54
-
-
16644401873
-
Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.206
-
McDermott DF, Regan MM, Clark JI et al. Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. J Clin Oncol 2005; 23: 133-141. (Pubitemid 41702632)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.1
, pp. 133-141
-
-
McDermott, D.F.1
Regan, M.M.2
Clark, J.I.3
Flaherty, L.E.4
Weiss, G.R.5
Logan, T.F.6
Kirkwood, J.M.7
Gordon, M.S.8
Sosman, J.A.9
Ernstoff, M.S.10
Tretter, C.P.G.11
Urba, W.J.12
Smith, J.W.13
Margolin, K.A.14
Mier, J.W.15
Gollob, J.A.16
Dutcher, J.P.17
Atkins, M.B.18
-
55
-
-
0042914703
-
Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
-
Yang JC, Sherry RM, Steinberg SM et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol 2003; 21: 3127-3132.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3127-3132
-
-
Yang, J.C.1
Sherry, R.M.2
Steinberg, S.M.3
-
56
-
-
0033514050
-
Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomized controlled trial: Medical Research Council, Renal Cancer Collaborators
-
Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomized controlled trial: Medical Research Council, Renal Cancer Collaborators. Lancet 1999; 353: 14-17.
-
(1999)
Lancet
, vol.353
, pp. 14-17
-
-
-
58
-
-
0035048096
-
Cytokine therapy for metastatic renal cell carcinoma
-
Bukowski RM. Cytokine therapy for metastatic renal cell carcinoma. Semin Urol Oncol 2001; 19: 148-154. (Pubitemid 32410348)
-
(2001)
Seminars in Urologic Oncology
, vol.19
, Issue.2
, pp. 148-154
-
-
Bukowshi, R.M.1
-
59
-
-
0036138580
-
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
DOI 10.1200/JCO.20.1.289
-
Motzer RJ, Bacik J, Murphy BA et al. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 2002; 20: 289-296. (Pubitemid 34032623)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.1
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.A.3
Russo, P.4
Mazumdar, M.5
-
60
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.02.2574
-
Motzer RJ, Michaelson MD, Redman BG et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006; 24: 16-24. (Pubitemid 46630489)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
Hudes, G.R.4
Wilding, G.5
Figlin, R.A.6
Ginsberg, M.S.7
Kim, S.T.8
Baum, C.M.9
Deprimo, S.E.10
Li, J.Z.11
Bello, C.L.12
Theuer, C.P.13
George, D.J.14
Rini, B.I.15
-
61
-
-
35548931472
-
Randomized phase III trial of first-line treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: Final results
-
Szcylik C, Demkow T, Staehler M et al. Randomized phase III trial of first-line treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: final results. J Clin Oncol 2007; 25: 5025.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5025
-
-
Szcylik, C.1
Demkow, T.2
Staehler, M.3
-
62
-
-
48649094719
-
Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (MRCC)
-
abstr 5024
-
Figlin RA, Hutson TE, Tomczak P et al. Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (MRCC). J Clin Oncol 2008; 26(Suppl): 256S (abstr 5024).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Figlin, R.A.1
Hutson, T.E.2
Tomczak, P.3
-
63
-
-
34548315347
-
Final results of the randomized phase III trial of sorafenib in advanced renal cell carcinoma: Survival and biomarker analysis
-
abstr 5023
-
Bukowski RM, Eisen T, Szczylik C et al. Final results of the randomized phase III trial of sorafenib in advanced renal cell carcinoma: survival and biomarker analysis. J Clin Oncol 2007; 25(Suppl): 240S (abstr 5023).
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Bukowski, R.M.1
Eisen, T.2
Szczylik, C.3
-
64
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
DOI 10.1056/NEJMoa021491
-
Yang JC, Haworth L, Sherry RM et al. Randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003; 349: 427-434. (Pubitemid 36910021)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
65
-
-
35648938219
-
Randomized phase DJ study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
-
Bukowski RM, Kabbinavar FF, Figlin RA et al. Randomized phase DJ study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. J Clin Oncol 2007; 25: 4536-4541.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4536-4541
-
-
Bukowski, R.M.1
Kabbinavar, F.F.2
Figlin, R.A.3
-
66
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
Atkins MB, Hidalgo M, Stadler WM et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol 2004; 22: 909-912.
-
(2004)
J Clin Oncol
, vol.22
, pp. 909-912
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
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