메뉴 건너뛰기




Volumn 32, Issue 1, 2010, Pages 130-142

Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons

Author keywords

acetylcholine; ChAT; CHT1; narcolepsy; VAChT

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINE ACETYLTRANSFERASE; MESSENGER RNA; NEUROPEPTIDE RECEPTOR; OREXIN RECEPTOR; UNCLASSIFIED DRUG; VESICULAR ACETYLCHOLINE TRANSPORTER;

EID: 77954411827     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2010.07259.x     Document Type: Article
Times cited : (27)

References (63)
  • 3
    • 34347387212 scopus 로고    scopus 로고
    • The high-affinity choline transporter: A critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice
    • Bazalakova, M.H. Blakely, R.D. (2006) The high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice. Handb. Exp. Pharmacol., 175, 525 544.
    • (2006) Handb. Exp. Pharmacol. , vol.175 , pp. 525-544
    • Bazalakova, M.H.1    Blakely, R.D.2
  • 4
    • 0035869483 scopus 로고    scopus 로고
    • Acetylcholine becomes the major excitatory neurotransmitter in the hypothalamus in vitro in the absence of glutamate excitation
    • Belousov, A.B., O'Hara, B.F. Denisova, J.V. (2001) Acetylcholine becomes the major excitatory neurotransmitter in the hypothalamus in vitro in the absence of glutamate excitation. J. Neurosci., 21, 2015 2027.
    • (2001) J. Neurosci. , vol.21 , pp. 2015-2027
    • Belousov, A.B.1    O'Hara, B.F.2    Denisova, J.V.3
  • 5
    • 0036715172 scopus 로고    scopus 로고
    • Calcium-dependent regulation of cholinergic cell phenotype in the hypothalamus in vitro
    • Belousov, A.B., Hunt, N.D., Raju, R.P. Denisova, J.V. (2002) Calcium-dependent regulation of cholinergic cell phenotype in the hypothalamus in vitro. J. Neurophysiol., 88, 1352 1362.
    • (2002) J. Neurophysiol. , vol.88 , pp. 1352-1362
    • Belousov, A.B.1    Hunt, N.D.2    Raju, R.P.3    Denisova, J.V.4
  • 7
    • 61849169563 scopus 로고    scopus 로고
    • Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels
    • Brooks, N.P., Mexal, S. Stitzel, J.A. (2009) Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels. Brain Res., 1263, 1 9.
    • (2009) Brain Res. , vol.1263 , pp. 1-9
    • Brooks, N.P.1    Mexal, S.2    Stitzel, J.A.3
  • 8
    • 0036546690 scopus 로고    scopus 로고
    • Direct and indirect excitation of laterodorsal tegmental neurons by hypocretin/orexin peptides: Implications for wakefulness and narcolepsy
    • Burlet, S., Tyler, C.J. Leonard, C.S. (2002) Direct and indirect excitation of laterodorsal tegmental neurons by hypocretin/orexin peptides: implications for wakefulness and narcolepsy. J. Neurosci., 22, 2862 2872.
    • (2002) J. Neurosci. , vol.22 , pp. 2862-2872
    • Burlet, S.1    Tyler, C.J.2    Leonard, C.S.3
  • 10
    • 2942672555 scopus 로고    scopus 로고
    • M2 muscarinic receptors in pontine reticular formation of C57BL/6J mouse contribute to rapid eye movement sleep generation
    • Coleman, C.G., Lydic, R. Baghdoyan, H.A. (2004) M2 muscarinic receptors in pontine reticular formation of C57BL/6J mouse contribute to rapid eye movement sleep generation. Neuroscience, 126, 821 830.
    • (2004) Neuroscience , vol.126 , pp. 821-830
    • Coleman, C.G.1    Lydic, R.2    Baghdoyan, H.A.3
  • 12
    • 12344268679 scopus 로고    scopus 로고
    • Stimulation of cortical acetylcholine release by orexin A
    • Fadel, J., Pasumarthi, R. Reznikov, L.R. (2005) Stimulation of cortical acetylcholine release by orexin A. Neuroscience, 130, 541 547.
    • (2005) Neuroscience , vol.130 , pp. 541-547
    • Fadel, J.1    Pasumarthi, R.2    Reznikov, L.R.3
  • 13
    • 2542599213 scopus 로고    scopus 로고
    • The choline transporter resurfaces: New roles for synaptic vesicles?
    • Ferguson, S.M. Blakely, R.D. (2004) The choline transporter resurfaces: new roles for synaptic vesicles? Mol. Interv., 4, 22 37.
    • (2004) Mol. Interv. , vol.4 , pp. 22-37
    • Ferguson, S.M.1    Blakely, R.D.2
  • 15
    • 2942535959 scopus 로고    scopus 로고
    • Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice
    • Ferguson, S.M., Bazalakova, M., Savchenko, V., Tapia, J.C., Wright, J. Blakely, R.D. (2004) Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice. Proc. Natl Acad. Sci. USA, 101, 8762 8767.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 8762-8767
    • Ferguson, S.M.1    Bazalakova, M.2    Savchenko, V.3    Tapia, J.C.4    Wright, J.5    Blakely, R.D.6
  • 16
    • 0016468979 scopus 로고
    • A rapid radiochemical method for the determination of choline acetyltransferase
    • Fonnum, F. (1975) A rapid radiochemical method for the determination of choline acetyltransferase. J. Neurochem., 24, 407 409.
    • (1975) J. Neurochem. , vol.24 , pp. 407-409
    • Fonnum, F.1
  • 17
    • 35448996142 scopus 로고    scopus 로고
    • Food-elicited increases in cortical acetylcholine release require orexin transmission
    • Frederick-Duus, D., Guyton, M.F. Fadel, J. (2007) Food-elicited increases in cortical acetylcholine release require orexin transmission. Neuroscience, 149, 499 507.
    • (2007) Neuroscience , vol.149 , pp. 499-507
    • Frederick-Duus, D.1    Guyton, M.F.2    Fadel, J.3
  • 18
    • 34548472182 scopus 로고    scopus 로고
    • Promoter analysis of human glutamate carboxypeptidase II
    • Han, L., Wong, D.L., Tsai, G., Jiang, Z. Coyle, J.T. (2007) Promoter analysis of human glutamate carboxypeptidase II. Brain Res., 1170, 1 12.
    • (2007) Brain Res. , vol.1170 , pp. 1-12
    • Han, L.1    Wong, D.L.2    Tsai, G.3    Jiang, Z.4    Coyle, J.T.5
  • 19
    • 0035006525 scopus 로고    scopus 로고
    • Hypocretin/orexin, sleep and narcolepsy
    • Hungs, M. Mignot, E. (2001) Hypocretin/orexin, sleep and narcolepsy. Bioessays, 23, 397 408.
    • (2001) Bioessays , vol.23 , pp. 397-408
    • Hungs, M.1    Mignot, E.2
  • 20
    • 0025343860 scopus 로고
    • Immunohistochemical study of choline acetyltransferase-immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat
    • Jones, B.E. (1990) Immunohistochemical study of choline acetyltransferase-immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat. J. Comp. Neurol., 295, 485 514.
    • (1990) J. Comp. Neurol. , vol.295 , pp. 485-514
    • Jones, B.E.1
  • 24
    • 0001858941 scopus 로고    scopus 로고
    • Behavioral and polysomnographic characterization of orexin-1 receptor and orexin-2 receptor double knockout mice
    • Kisanuki, Y.Y., Chemelli, R.M., Tokita, S., Willie, J.T., Sinton, C.M. Yanagisawa, M. (2001) Behavioral and polysomnographic characterization of orexin-1 receptor and orexin-2 receptor double knockout mice. Sleep, 24, A22.
    • (2001) Sleep , vol.24 , pp. 22
    • Kisanuki, Y.Y.1    Chemelli, R.M.2    Tokita, S.3    Willie, J.T.4    Sinton, C.M.5    Yanagisawa, M.6
  • 25
    • 3042552335 scopus 로고    scopus 로고
    • Hypocretin/orexin peptide signaling in the ascending arousal system: Elevation of intracellular calcium in the mouse dorsal raphe and laterodorsal tegmentum
    • Kohlmeier, K.A., Inoue, T. Leonard, C.S. (2004) Hypocretin/orexin peptide signaling in the ascending arousal system: elevation of intracellular calcium in the mouse dorsal raphe and laterodorsal tegmentum. J. Neurophysiol., 92, 221 235.
    • (2004) J. Neurophysiol. , vol.92 , pp. 221-235
    • Kohlmeier, K.A.1    Inoue, T.2    Leonard, C.S.3
  • 26
    • 57349100377 scopus 로고    scopus 로고
    • Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: Noisy cation current activation and selective enhancement of ca transients mediated by L-type calcium channels
    • Kohlmeier, K.A., Watanabe, S., Tyler, C.J., Burlet, S. Leonard, C.S. (2008) Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of ca transients mediated by L-type calcium channels. J. Neurophysiol., 100, 2265 2281.
    • (2008) J. Neurophysiol. , vol.100 , pp. 2265-2281
    • Kohlmeier, K.A.1    Watanabe, S.2    Tyler, C.J.3    Burlet, S.4    Leonard, C.S.5
  • 27
    • 0035136410 scopus 로고    scopus 로고
    • Carbachol models of REM sleep: Recent developments and new directions
    • Kubin, L. (2001) Carbachol models of REM sleep: recent developments and new directions. Arch. Ital. Biol., 139, 147 168.
    • (2001) Arch. Ital. Biol. , vol.139 , pp. 147-168
    • Kubin, L.1
  • 29
    • 0034120302 scopus 로고    scopus 로고
    • Application of real-time polymerase chain reaction for the quantitation of interleukin-1beta mRNA upregulation in brain ischemic tolerance
    • Li, X. Wang, X. (2000) Application of real-time polymerase chain reaction for the quantitation of interleukin-1beta mRNA upregulation in brain ischemic tolerance. Brain Res. Protoc., 5, 211 217.
    • (2000) Brain Res. Protoc. , vol.5 , pp. 211-217
    • Li, X.1    Wang, X.2
  • 30
    • 0033529520 scopus 로고    scopus 로고
    • The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
    • Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P.J., Nishino, S. Mignot, E. (1999) The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell, 98, 365 376.
    • (1999) Cell , vol.98 , pp. 365-376
    • Lin, L.1    Faraco, J.2    Li, R.3    Kadotani, H.4    Rogers, W.5    Lin, X.6    Qiu, X.7    De Jong, P.J.8    Nishino, S.9    Mignot, E.10
  • 32
    • 0037114685 scopus 로고    scopus 로고
    • Microinjection of neostigmine into the pontine reticular formation of C57BL/6J mouse enhances rapid eye movement sleep and depresses breathing
    • Lydic, R., Douglas, C.L. Baghdoyan, H.A. (2002) Microinjection of neostigmine into the pontine reticular formation of C57BL/6J mouse enhances rapid eye movement sleep and depresses breathing. Sleep, 25, 835 841.
    • (2002) Sleep , vol.25 , pp. 835-841
    • Lydic, R.1    Douglas, C.L.2    Baghdoyan, H.A.3
  • 34
    • 33645988822 scopus 로고    scopus 로고
    • Virtues and woes of AChE alternative splicing in stress-related neuropathologies
    • Meshorer, E. Soreq, H. (2006) Virtues and woes of AChE alternative splicing in stress-related neuropathologies. TiNs, 29, 216 223.
    • (2006) TiNs , vol.29 , pp. 216-223
    • Meshorer, E.1    Soreq, H.2
  • 35
    • 0027511711 scopus 로고
    • Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: Induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems
    • Mignot, E., Nishino, S., Sharp, L.H., Arrigoni, J., Siegel, J.M., Reid, M.S., Edgar, D.M., Ciaranello, R.D. Dement, W.C. (1993) Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. J. Neurosci., 13, 1057 1064.
    • (1993) J. Neurosci. , vol.13 , pp. 1057-1064
    • Mignot, E.1    Nishino, S.2    Sharp, L.H.3    Arrigoni, J.4    Siegel, J.M.5    Reid, M.S.6    Edgar, D.M.7    Ciaranello, R.D.8    Dement, W.C.9
  • 40
    • 37549011413 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia
    • Pichiule, P., Chavez, J.C., Schmidt, A.M. Vannucci, S.J. (2007) Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia. J. Biol. Chem., 282, 36330 36340.
    • (2007) J. Biol. Chem. , vol.282 , pp. 36330-36340
    • Pichiule, P.1    Chavez, J.C.2    Schmidt, A.M.3    Vannucci, S.J.4
  • 41
    • 0032189780 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin
    • van den Pol, A.N., Gao, X.B., Obrietan, K., Kildruff, T.S. Belousov, A.B. (1998) Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. J. Neurosci., 18, 7962 7971.
    • (1998) J. Neurosci. , vol.18 , pp. 7962-7971
    • Van Den Pol, A.N.1    Gao, X.B.2    Obrietan, K.3    Kildruff, T.S.4    Belousov, A.B.5
  • 42
    • 11844267249 scopus 로고    scopus 로고
    • Microinjection of neostigmine into the pontine reticular formation of the mouse: Further evaluation of a proposed REM sleep enhancement technique
    • Pollock, M.S. Mistlberger, R.E. (2005) Microinjection of neostigmine into the pontine reticular formation of the mouse: further evaluation of a proposed REM sleep enhancement technique. Brain Res., 1031, 253 267.
    • (2005) Brain Res. , vol.1031 , pp. 253-267
    • Pollock, M.S.1    Mistlberger, R.E.2
  • 43
    • 0024407511 scopus 로고
    • Mapping neuronal inputs to REM sleep induction sites with carbachol-fluorescent microspheres
    • Quattrochi, J.J., Mamelak, A.N., Madison, R.D., Macklis, J.D. Hobson, J.A. (1989) Mapping neuronal inputs to REM sleep induction sites with carbachol-fluorescent microspheres. Science, 245, 984 986.
    • (1989) Science , vol.245 , pp. 984-986
    • Quattrochi, J.J.1    Mamelak, A.N.2    Madison, R.D.3    MacKlis, J.D.4    Hobson, J.A.5
  • 44
    • 47949132482 scopus 로고    scopus 로고
    • Orexins stimulate steroidogenic acute regulatory protein expression through multiple signaling pathways in human adrenal H295R cells
    • Ramanjaneya, M., Conner, A.C., Chen, J., Stanfield, P.R. Randeva, H.S. (2008) Orexins stimulate steroidogenic acute regulatory protein expression through multiple signaling pathways in human adrenal H295R cells. Endocrinology, 149, 4106 4115.
    • (2008) Endocrinology , vol.149 , pp. 4106-4115
    • Ramanjaneya, M.1    Conner, A.C.2    Chen, J.3    Stanfield, P.R.4    Randeva, H.S.5
  • 45
    • 0028343793 scopus 로고
    • Cholinergic mechanisms in canine narcolepsy-II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy
    • Reid, M.S., Siegel, J.M., Dement, W.C. Mignot, E. (1994a) Cholinergic mechanisms in canine narcolepsy-II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy. Neuroscience, 59, 523 530.
    • (1994) Neuroscience , vol.59 , pp. 523-530
    • Reid, M.S.1    Siegel, J.M.2    Dement, W.C.3    Mignot, E.4
  • 46
    • 0028100312 scopus 로고
    • Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors
    • Reid, M.S., Tafti, M., Nishino, S., Siegel, J.M., Dement, W.C. Mignot, E. (1994b) Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. Sleep, 17, 424 435.
    • (1994) Sleep , vol.17 , pp. 424-435
    • Reid, M.S.1    Tafti, M.2    Nishino, S.3    Siegel, J.M.4    Dement, W.C.5    Mignot, E.6
  • 47
    • 0028314282 scopus 로고
    • Cholinergic mechanisms in canine narcolepsy- I. Modulation of cataplexy via local drug administration into the pontine reticular formation
    • Reid, M.S., Tafty, M., Geary, J.N., Nishino, S., Siegel, J.M., Dement, W.C. Mignot, E. (1994c) Cholinergic mechanisms in canine narcolepsy- I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience, 59, 511 522.
    • (1994) Neuroscience , vol.59 , pp. 511-522
    • Reid, M.S.1    Tafty, M.2    Geary, J.N.3    Nishino, S.4    Siegel, J.M.5    Dement, W.C.6    Mignot, E.7
  • 49
    • 0022971071 scopus 로고
    • Cholinergic neurons of the laterodorsal tegmental nucleus: Efferent and afferent connections
    • Satoh, K. Fibiger, H.C. (1986) Cholinergic neurons of the laterodorsal tegmental nucleus: Efferent and afferent connections. J. Comp. Neurol., 253, 277 302.
    • (1986) J. Comp. Neurol. , vol.253 , pp. 277-302
    • Satoh, K.1    Fibiger, H.C.2
  • 50
    • 0028306032 scopus 로고
    • Target determination of neurotransmitter phenotype in sympathetic neurons
    • Schotzinger, R., Yin, X. Landis, S. (1994) Target determination of neurotransmitter phenotype in sympathetic neurons. J. Neurobiol., 25, 620 639.
    • (1994) J. Neurobiol. , vol.25 , pp. 620-639
    • Schotzinger, R.1    Yin, X.2    Landis, S.3
  • 51
    • 0027466299 scopus 로고
    • Aminergic and cholinergic afferents to REM sleep induction regions of the pontine reticular formation in the rat
    • Semba, K. (1993) Aminergic and cholinergic afferents to REM sleep induction regions of the pontine reticular formation in the rat. J. Comp. Neurol., 330, 543 556.
    • (1993) J. Comp. Neurol. , vol.330 , pp. 543-556
    • Semba, K.1
  • 52
    • 0025018187 scopus 로고
    • Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat
    • Semba, K., Reiner, P.B. Fibiger, H.C. (1990) Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat. Neuroscience, 38, 485 514.
    • (1990) Neuroscience , vol.38 , pp. 485-514
    • Semba, K.1    Reiner, P.B.2    Fibiger, H.C.3
  • 53
    • 39849091107 scopus 로고    scopus 로고
    • Spectrophotometric and colorimetric determination of protein concentration
    • Simonian, M.H. Smith, J.A. (2006) Spectrophotometric and colorimetric determination of protein concentration. Curr. Protoc. Mol. Biol., 10, 11A.
    • (2006) Curr. Protoc. Mol. Biol. , vol.10
    • Simonian, M.H.1    Smith, J.A.2
  • 55
    • 0031047887 scopus 로고    scopus 로고
    • Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog
    • Tafti, M., Nishino, S., Liao, W.C., Dement, W.C. Mignot, E. (1997) Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. J. Comp. Neurol., 379, 185 197.
    • (1997) J. Comp. Neurol. , vol.379 , pp. 185-197
    • Tafti, M.1    Nishino, S.2    Liao, W.C.3    Dement, W.C.4    Mignot, E.5
  • 59
    • 0002685341 scopus 로고
    • Ascending cholinergic pathways in the rat brain
    • In. Steriade, M. Biesold, D. eds. Oxford University Press
    • Wainer, B.H. Mesulam, M.M. (1990) Ascending cholinergic pathways in the rat brain. In Steriade, M. Biesold, D. (eds Brain Cholinergic Systems. Oxford University Press
    • (1990) Brain Cholinergic Systems.
    • Wainer, B.H.1    Mesulam, M.M.2
  • 60
    • 0019728944 scopus 로고
    • 2+ in the transmitter choice made by cultured sympathetic neurons
    • 2+ in the transmitter choice made by cultured sympathetic neurons. J. Neurosci., 1, 343 350.
    • (1981) J. Neurosci. , vol.1 , pp. 343-350
    • Walicke, P.A.1    Patterson, P.H.2
  • 61
    • 77954408679 scopus 로고    scopus 로고
    • Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center
    • Willie, J.T. (2005) Lessons From Sleepy Mice: Narcolepsy and the Orexin Neuropeptide System. Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center
    • (2005) Lessons from Sleepy Mice: Narcolepsy and the Orexin Neuropeptide System.
    • Willie, J.T.1
  • 63
    • 24944534978 scopus 로고    scopus 로고
    • Real-time PCR for mRNA quantitation
    • Wong, M.L. Medrano, J.F. (2005) Real-time PCR for mRNA quantitation. BioTechniques, 39, 75 85.
    • (2005) BioTechniques , vol.39 , pp. 75-85
    • Wong, M.L.1    Medrano, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.