Tocopherol induced angiogenesis in placental vascular network in late pregnant ewes

Reproductive Biology and Endocrinology

Volumn 8, Issue , 2010, Pages

  Kasimanickam, Ramanathan K ^a   Kasimanickam, Vanmathy R ^a   Rodriguez, Jacobo S ^a   Pelzer, Kevin D ^b   Sponenberg, Philip D ^b   Thatcher, Craig D ^c  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GAMMA TOCOPHEROL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; PLACEBO; PLACENTAL GROWTH FACTOR; TOCOPHEROL; VASCULOTROPIN; HYPOXIA INDUCIBLE FACTOR 1; PLACENTA PROTEIN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG TISSUE LEVEL; EWE; FEMALE; GENE EXPRESSION; GESTATIONAL AGE; MORPHOMETRICS; NONHUMAN; PLACENTA DEVELOPMENT; ALGORITHM; ANIMAL; BLOOD; BREEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; ORAL DRUG ADMINISTRATION; PLACENTA; PREGNANCY; RANDOMIZED CONTROLLED TRIAL; VASCULARIZATION;

ADMINISTRATION, ORAL; ALGORITHMS; ANIMALS; FEMALE; GENE EXPRESSION REGULATION; GESTATIONAL AGE; HYPOXIA-INDUCIBLE FACTOR 1; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; PREGNANCY, ANIMAL; TOCOPHEROLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954397964     PISSN: None     EISSN: 14777827     Source Type: Journal    
DOI: 10.1186/1477-7827-8-86     Document Type: Article

References (50)

1. Folkman J, Klagsbrun M. Angiogenic factors. Science 1987, 235:442-447. 10.1126/science.2432664, 2432664.
2. Sherer DM, Abulafia O. Angiogenesis during implantation, and placental and early embryonic development. Placenta 2001, 22:1-13. 10.1053/plac.2000.0588, 11162347.
3. Gruber M, Simon MC. Hypoxia-inducible factors, hypoxia, and tumor angiogenesis. Curr Opin Hematol 2006, 13:169-174. 10.1097/01.moh.0000219663.88409.35, 16567961.
4. Teicher BA. Hypoxia, tumor endothelium, and targets for therapy. Adv Exp Med Biol 2005, 566:31-38. full_text, 16594131.
5. Rojas A, Figueroa H, Re L, Morales MA. Oxidative stress at the vascular wall: Mechanistic and pharmacological aspects. Arch Med Res 2006, 37:436-448. 10.1016/j.arcmed.2005.11.012, 16624640.
6. Sauer H, Wartenberg M. Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor induced angiogenesis. Antioxid Redox Signal 2005, 7:1423-434. 10.1089/ars.2005.7.1423, 16356105.
7. Liu Y, Zhao H, Li H, Kalyanaraman B, Nicolosi AC, Gutterman DD. Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res 2003, 93:573-580. 10.1161/01.RES.0000091261.19387.AE, 12919951.
8. Zafari AM, Ushio-Fukai M, Akers M, Yin Q, Shah A, Harrison DG, Taylor WR, Griendling KK. Role of NADH/NADPH oxidase derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension 1998, 32:488-495.
9. Jones DP. Radical-free biology of oxidative stress. Am J Physiol Cell Physiol 2008, 295:C849-868. 10.1152/ajpcell.00283.2008, 2575825, 18684987.
10. Burton GJ, Hempstock J, Jauniaux E. Oxygen, early embryonic metabolism and radical mediated embryopathies. Reprod Biomed Online 2003, 6:84-96. 10.1016/S1472-6483(10)62060-3, 12626148.
11. Wiznitzer A, Furman B, Mazor M, Reece EA. The role of prostanoids in the development of diabetic embryopathy. Sem Reprod Endocrinol 1999, 17:175-181.
12. Jauniaux E, Hempstock J, Greenwold N, Burton GJ. Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancy. Am J Pathol 2003, 162:115-125. 1851128, 12507895.
13. Jauniaux E, Watson AL, Hempstock J, Bao Y-P, Skepper JN, Burton GJ. Onset of placental blood flow and trophoblastic oxidative stress: a possible factor in human early pregnancy failure. Am J Pathol 2000, 157:2111-122. 1885754, 11106583.
14. Traber MG, Burton GW, Hamilton RL. Vitamin E trafficking. Ann N Y Acad Sci 2004, 1031:1-12. 10.1196/annals.1331.001, 15753129.
15. Williamson KS, Gabbita SP, Mou S, West M, Pye QN, Markesbery WR, Cooney RV, Grammas P, Reimann-Phillip U, Floyd RA, Hensley K. The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain. Nitric Oxide 2002, 6:221-227. 10.1006/niox.2001.0399, 11890747.
16. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, Mordan LJ. γ-Tocopherol detoxification of nitrogen dioxide: Superiority to α-tocopherol. Proc Natl Acad Sci USA 1993, 90:1771-1775. 10.1073/pnas.90.5.1771, 45961, 8446589.
17. Saldeen T, Li D, Mehta JL. Differential effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis. J Am Coll Cardiol 1999, 34:1208-1215. 10.1016/S0735-1097(99)00333-2, 10520814.
18. Burton GW, Traber MG. Vitamin E: antioxidant activity, biokinetics, and bioavailability. Ann Rev of Nutr 1990, 10:357-382.
19. Ozer NK, Sirikci O, Taha S, San T, Moser U, Azzi A. Effect of vitamin E and probucol on dietary cholesterol-induced atherosclerosis in rabbits. Free Radic Biol Med 1998, 24:226-233. 10.1016/S0891-5849(97)00136-6, 9433896.
20. Keaney JF, Gaziano JM, Xu A, Frei B, Curran-Celentano J, Shwaery GT, Loscalzo J, Vita JA. Low-dose α-tocopherol improves and high-dose α-tocopherol worsens endothelial vasodilator function in cholesterol- fed rabbits. J Clin Invest 1994, 93:844-851. 10.1172/JCI117039, 293946, 8113416.
21. Kontush A, Finckh B, Karten B, Kohlschutter A, Beisiegel U. Antioxidant and prooxidant activity of α-tocopherol in human plasma and low density lipoprotein. J Lipid Res 1996, 37:1436-1448.
22. Versari D, Daghini E, Rodriguez-Porcel M, Sattler K, Galili O, Pilarczyk K, Napoli C, Lerman LO, Lerman A. Chronic antioxidant supplementation impairs coronary endothelial function and myocardial perfusion in normal pigs. Hypertension 2006, 47:475-481. 10.1161/01.HYP.0000201445.77125.26, 16446399.
23. Shibata A, Nakagawa K, Sookwong P, Tsuduki T, Oikawa S, Miyazawa T. δ-Tocotrienol suppresses VEGF induced angiogenesis whereas r-tocopherol does not. J Agri Food Chem 2009, 57:8696-8704.
24. Hewitt DP, Mark PJ, Waddell BJ. Glucocorticoids prevent the normal increase in placental vascularity during late pregnancy in the rat. Endocrinology 2006, 147:5568-5574. 10.1210/en.2006-0825, 16959835.
25. Regnaulta TRH, Galanb HL, Parkera TA, Anthony RV. Placental development in normal and compromised pregnancies-A review. Placenta 2002, 23:S119-129. 10.1053/plac.2002.0792, 11978069.
26. Panfili G, Fratianni A, Irano M. Normal phase High-Performance Liquid Chromatography method for the determination of tocopherols and tocotrienols in Cereals. J Agric Food Chem 2003, 51:3940-3944. 10.1021/jf030009v, 12822927.
27. Katsanidis E, Addis PB. Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. Free Radic Biol Med 1999, 27:1137-1140. 10.1016/S0891-5849(99)00205-1, 10641704.
28. Tsatsaris V, Goffin F, Munaut C, Brichant JF, Pignon MR, Noel A, Schaaps JP, Cabrol D, Frankenne F, Foidart JM. Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences. J Clin Endocrinol Metab 2003, 88:5555-5563. 10.1210/jc.2003-030528, 14602804.
29. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
30. Doukas CN, Maglogiannis I, Chatziioannou AA. Computer supported angiogensis quantification using image analysis and statistical averaging. IEEE Transact Informat Tech Biomed 2008, 12:650-657.
31. Talavera-Adame D, Xiong Y, Zhoa T, Arias AE, Sierra-Honigmann MR, Farkas DL. Quantitative and morphometric evaluation of the angiogenic effects of leptin. J Biomed Optics 2008, 13:064017, 1-7.
32. Traber MG, Elsner A, Brigelius-Flohe R. Synthetic as compared with natural vitamin E is preferentially excreted as alpha-CEHC in human urine: studies using deuterated alpha-tocopheryl acetates. FEBS Lett 1998, 437:145-148. 10.1016/S0014-5793(98)01210-1, 9804189.
33. Lodge JK, Hall WL, Jeanes YM, Proteggente AR. Physiological factors influencing vitamin E biokinetics. Ann N Y Acad Sci 2004, 1031:60-73. 10.1196/annals.1331.006, 15753134.
34. Behrens WA, Madère R. Alpha- and gamma tocopherol concentrations in human serum. J Am Coll Nutr 1986, 5:91-106.
35. Bates CJ, Mishra GD, Prentice A. Gamma-tocopherol as a possible marker for nutrition-related risk: results from four National Diet and Nutrition Surveys in Britain. Br J Nutr 2004, 92:137-150. 10.1079/BJN20041156, 15230997.
36. Ferrari L, Herber R, Batt AM, Siest G. Differential effects of human recombinant interleukin-1 beta and dexamethasone on hepatic drug metabolizing enzymes in male and female rats. Biochem Pharmacol 1993, 45:2269-2277. 10.1016/0006-2952(93)90198-6, 8517867.
37. Shedlofsky SI, Israel BC, McClain CJ, Hill DB, Blouin RA. Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism. J Clin Invest 1994, 94:2209-2214. 10.1172/JCI117582, 330046, 7989576.
38. Leonard SW, Paterson E, Atkinson JK, Ramakrishnan R, Cross CE, Traber MG. Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production. Free Radic Biol Med 2005, 38:857-866. 10.1016/j.freeradbiomed.2004.12.001, 15749381.
39. Traber MG, Burton GW, Hughes L, Ingold KU, Hidaka H, Malloy M, Kane J, Hyams J, Kayden HJ. Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism. J Lipid Res 1992, 33:1171-182.
40. Zygmunt M, Herr F, Munstedt K, Lang U, Liang OD. Angiogenesis and vasculogenesis in pregnancy. Eur J Obstet Gynecol Reprod Biol 2003, 110:S10-S18. 10.1016/S0301-2115(03)00168-4, 12965086.
41. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995, 1:27-31. 10.1038/nm0195-27, 7584949.
42. Reynolds LP, Borowicz PP, Vonnahme KA, Johnson ML, Grazul-Bilska AT, Redmer DA, Caton JS. Placental angiogenesis in sheep models of compromised pregnancy. J Physiol 2005, 15:43-58.
43. Borowicz PP, Arnold DR, Johnson ML, Grazul-Bilska AT, Redmer DA, Reynolds LP. Placental growth throughout the last two thirds of pregnancy in sheep: vascular development and angiogenic factor expression. Biol Reprod 2007, 76:259-267. 10.1095/biolreprod.106.054684, 17050858.
44. Ahmad S, Hewett PW, Wang P, Al-Ani B, Cudmore M, Fujisawa T, Haigh JJ, le Noble F, Wang L, Mukhopadhyay D, Ahmed A. Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis. Circ Res 2006, 99:715-722. 10.1161/01.RES.0000243989.46006.b9, 16946136.
45. Cooney RV, Harwood PJ, Franke AA, Narala K, Sundstorm AK, Berggren PO, Mordan LJ. Products of gamma-tocopherol reaction with NO2 and their formation in rat insulinoma (RINm5F) cells. Free Radic Biol Med 1995, 19:259-269. 10.1016/0891-5849(95)00019-T, 7557540.
46. Carr A, Frei B. The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide. Free Radic Biol Med 2000, 28:1806-1814. 10.1016/S0891-5849(00)00225-2, 10946222.
47. Semenza GL. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999, 15:551-578. 10.1146/annurev.cellbio.15.1.551, 10611972.
48. Jain S, Maltepe E, Lu MM, Simon C, Bradfield CA. Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mech Dev 1998, 73:117-123. 10.1016/S0925-4773(98)00038-0, 9545558.
49. Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu C, Labosky PA, Simon MC, Keith B. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006, 20:557-570. 10.1101/gad.1399906, 1410808, 16510872.
50. Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, Jeltsch M, Mitchell C, Alitalo K, Shima D, Betsholtz C. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 2003, 161:1163-1177. 10.1083/jcb.200302047, 2172999, 12810700.