Hypoxia, tumor endothelium, and targets for therapy

Advances in Experimental Medicine and Biology

Volumn 566, Issue , 2005, Pages 31-38

  Teicher, Beverly A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; BIOINFORMATICS; CELL ISOLATION; CONFERENCE PAPER; ENDOTHELIUM CELL; HUMAN; HYPOXIA; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; SERIAL ANALYSIS OF GENE EXPRESSION; TUMOR CELL; TUMOR CLASSIFICATION; TUMOR VOLUME;

ANIMALS; ANOXIA; CELL LINE, TUMOR; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; HUMANS; INDOLES; MICE; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33646883484     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/0-387-26206-7_5     Document Type: Conference Paper

References (15)

1. C. M. Doll, M. Milosevic, M. Pintilie, R. P. Hill, and A. W. Fyles, Estimating hypoxic status in human tumors: A simulation using Eppendorf oxygen probe data in cervical cancer patients, Int. J. Radiat. Oncol. Biol. Phys. 55(5), 1239-1246 (2003).
2. A. Fyles, M. Milosevic, D. Hedley, M. Pintilie, W. Levin, L. Manchul, and R. P. Hill, Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer, J. Clin. Oncol. 20(3), 680-687 (2002).
3. J.-Y. Wang, K.-Y. Chen, J.-T. Wang, J.-H. Chen, J.-W. Lin, H.-C. Wang, L.-N. Lee, and P.-C. Yang, Outcome and prognostic factors for patients with non-small cell lung cancer and severe radiation pneumonitis, Int. J. Radiat. Oncol. Biol. Phys. 54(3), 735-741 (2002).
4. J. Dunst, T. Kuhnt, H. G. Strauss, U. Krause, T. Pelz, H. Koelbl, and G. Haensgen, Anemia in cervical cancers: impact on survival, patterns of relapse, and association with hypoxia and angiogenesis, Int. J. Radiat. Oncol. Biol. Phys. 56(3), 778-787 (2003).
5. B. Movsas, J. D. Chapman, A. L. Hanlon, E. M. Horwitz, W. H. Pinover, R. E. Greenberg, C. Stobbe, and G. E. Hanks, Hypoxia in human prostate carcinoma: An Eppendorf PO2 study, Am. J. Clin. Oncol. 24(5), 458-461 (2001).
6. P. Subarsky, and R. P. Hill, The hypoxic tumor microenvironment and metastatic progression, Clin. Exp. Metastasis 20, 237-250 (2003).
7. S. A. Holden, Y. Emi, Y. Kakeji, D. Northey, and B. A. Teicher, Host distribution and response to antitumor alkylating agents of EMT-6 tumor cells from subcutaneous tumor implants, Cancer Chemother. Pharmacol. 40, 87-93 (1997).
8. B. A. Teicher, G. Ara, S. R. Keyes, R. S. Herbst, and E. Frei III, Acute in vivo resistance in high-dose therapy, Clin. Cancer Res. 4, 483-491 (1998).
9. B. St. Croix, C. Rago, V. Velculescu, G. Traverso, K. E. Romans, E. Montgomery, A. Lai, G. J. Riggins, C. Lengauer, B. Vogelstein, and K. W. Kinzler, Genes expressed in human tumor endothelium, Science 289(5482), 1197-1202 (2000).
10. R. G. Bagley, J. Walter-Yohrling, X. Cao, W. Weber, B. Simons, B. P. Cook, S. D. Chartrand, C. Wang, S. L. Madden, and B. A. Teicher, Endothelial precursor cells as a model of tumor endothelium: characterization and comparison with mature endothelial cells, Cancer Res. 63(18), 5866-5873 (2003).
11. Y. Kakeji, and B. A. Teicher, Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents, Invest. New Drugs 15, 39-48 (1997).
12. K. A. Keyes, L. Mann, K. Cox, P. Treadway, P. Iversen, Y.-F. Chen, and B. A. Teicher, Circulating angiogenic growth factor levels in mice bearing human tumors using Luminex multiplex technology, Cancer Chemother. Pharmacol. 51, 321-327 (2003).
13. K. Keyes, K. Cox, P. Treadway, L. Mann, C. Shih, M. M. Faul, and B. A. Teicher, An in vitro tumor model: analysis of angiogenic factor expression after chemotherapy, Cancer Res. 62, 5597-5602 (2002).
14. B. A. Teicher, K. Menon, E. Alvarez, E. Galbreath, C. Shih, and M. M. Faul, Antiangiogenic and antitumor effects of a protein Kinase Cb inhibitor in human T98G glioblastoma multiforme xenografts, Clin. Cancer Res. 7, 634-640 (2001).
15. K. A. Keyes, L. Mann, M. Sherman, E. Galbreath, L. Schirtzinger, D. Ballard, Y.-F. Chen, P. Iversen, and B. A. Teicher, LY317615 decreases plasma VEGF levels in human tumor xenograft bearing mice, Cancer Chemother. Pharmacol. 53(2), 133-140 (2003).