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Volumn 24, Issue 3, 2010, Pages 160-165

The role of indoleamine 2,3 dioxygenase in the induction of immune tolerance in organ transplantation

Author keywords

[No Author keywords available]

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; TRYPTOPHAN;

EID: 77954386836     PISSN: 0955470X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trre.2010.04.003     Document Type: Review
Times cited : (19)

References (51)
  • 1
    • 0021845998 scopus 로고
    • Indoleamine 2,3-dioxygenase-with special reference to the mechanism of interferon action
    • Hayaishi O. Indoleamine 2,3-dioxygenase-with special reference to the mechanism of interferon action. Biken J 1985, 28:39-49.
    • (1985) Biken J , vol.28 , pp. 39-49
    • Hayaishi, O.1
  • 2
    • 0023077208 scopus 로고
    • Indoleamine 2,3-dioxygenase
    • Yoshida R., Hayaishi O. Indoleamine 2,3-dioxygenase. Methods Enzymol 1987, 142:188-195.
    • (1987) Methods Enzymol , vol.142 , pp. 188-195
    • Yoshida, R.1    Hayaishi, O.2
  • 4
    • 0033376234 scopus 로고    scopus 로고
    • Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway
    • Thomas S.R., Stocker R. Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway. Redox Rep 1999, 4:199-220.
    • (1999) Redox Rep , vol.4 , pp. 199-220
    • Thomas, S.R.1    Stocker, R.2
  • 5
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: tolerance and tryptophan catabolism
    • Mellor A.L., Munn D.H. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004, 4:762-774.
    • (2004) Nat Rev Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 6
    • 0037769110 scopus 로고    scopus 로고
    • Dendritic cells in immunity and tolerance-do they display opposite functions?
    • Moser M. Dendritic cells in immunity and tolerance-do they display opposite functions?. Immunity 2003, 19:5-8.
    • (2003) Immunity , vol.19 , pp. 5-8
    • Moser, M.1
  • 7
    • 0345827684 scopus 로고    scopus 로고
    • Dendritic cells: emerging pharmacological targets of immunosuppressive drugs
    • Hackstein H., Thomson A.W. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol 2004, 4:24-34.
    • (2004) Nat Rev Immunol , vol.4 , pp. 24-34
    • Hackstein, H.1    Thomson, A.W.2
  • 8
    • 0035291879 scopus 로고    scopus 로고
    • Systemic and local immunosuppression in pancreatic cancer patients
    • von Bernstorff W., Voss M., Freichel S., et al. Systemic and local immunosuppression in pancreatic cancer patients. Clin Cancer Res 2001, 7(3 Suppl):925s-932s.
    • (2001) Clin Cancer Res , vol.7 , Issue.3 SUPPL
    • von, B.W.1    Voss, M.2    Freichel, S.3
  • 9
    • 13544276554 scopus 로고    scopus 로고
    • Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function
    • Koneru M., Schaer D., Monu N., et al. Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function. J Immunol 2005, 174:1830-1840.
    • (2005) J Immunol , vol.174 , pp. 1830-1840
    • Koneru, M.1    Schaer, D.2    Monu, N.3
  • 10
    • 0028925944 scopus 로고
    • Negative transcriptional regulation in anergic T cells
    • Becker J.C., Brabletz T., Kirchner T., et al. Negative transcriptional regulation in anergic T cells. Proc Natl Acad Sci U S A 1995, 92:2375-2378.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2375-2378
    • Becker, J.C.1    Brabletz, T.2    Kirchner, T.3
  • 11
    • 1642396607 scopus 로고    scopus 로고
    • Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
    • Munn D.H., Sharma M.D., Mellor A.L. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J Immunol 2004, 172:4100-4110.
    • (2004) J Immunol , vol.172 , pp. 4100-4110
    • Munn, D.H.1    Sharma, M.D.2    Mellor, A.L.3
  • 12
    • 0019748201 scopus 로고
    • Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung
    • Yoshida R., Urade Y., Nakata K., et al. Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung. Arch Biochem Biophys 1981, 212:629-637.
    • (1981) Arch Biochem Biophys , vol.212 , pp. 629-637
    • Yoshida, R.1    Urade, Y.2    Nakata, K.3
  • 13
    • 2142754480 scopus 로고    scopus 로고
    • Nitric oxide-mediated regulation of gamma interferon-induced bacteriostasis: inhibition and degradation of human indoleamine 2,3-dioxygenase
    • Hucke C., MacKenzie C.R., Adjogble K.D., et al. Nitric oxide-mediated regulation of gamma interferon-induced bacteriostasis: inhibition and degradation of human indoleamine 2,3-dioxygenase. Infect Immun 2004, 72:2723-2730.
    • (2004) Infect Immun , vol.72 , pp. 2723-2730
    • Hucke, C.1    MacKenzie, C.R.2    Adjogble, K.D.3
  • 14
    • 0037090313 scopus 로고    scopus 로고
    • Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses
    • Mellor A.L., Keskin D.B., Johnson T., et al. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. J Immunol 2002, 168:3771-3776.
    • (2002) J Immunol , vol.168 , pp. 3771-3776
    • Mellor, A.L.1    Keskin, D.B.2    Johnson, T.3
  • 15
    • 0033215041 scopus 로고    scopus 로고
    • Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?
    • Mellor A.L., Munn D.H. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?. Immunol Today 1999, 20:469-473.
    • (1999) Immunol Today , vol.20 , pp. 469-473
    • Mellor, A.L.1    Munn, D.H.2
  • 16
    • 0038281451 scopus 로고    scopus 로고
    • Tryptophan catabolism and regulation of adaptive immunity
    • Mellor A.L., Munn D.H. Tryptophan catabolism and regulation of adaptive immunity. J Immunol 2003, 170:5809-5813.
    • (2003) J Immunol , vol.170 , pp. 5809-5813
    • Mellor, A.L.1    Munn, D.H.2
  • 17
    • 0032555614 scopus 로고    scopus 로고
    • Prevention of allogeneic fetal rejection by tryptophan catabolism
    • Munn D.H., Zhou M., Attwood J.T., et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998, 281:1191-1193.
    • (1998) Science , vol.281 , pp. 1191-1193
    • Munn, D.H.1    Zhou, M.2    Attwood, J.T.3
  • 18
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 19
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995, 155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 20
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot J.D., Rasmussen J.P., Gavin M.A., et al. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005, 6:1142-1151.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3
  • 21
    • 34247376017 scopus 로고    scopus 로고
    • Tryptophan catabolism in IDO+ plasmacytoid dendritic cells
    • Fallarino F., Gizzi S., Mosci P., et al. Tryptophan catabolism in IDO+ plasmacytoid dendritic cells. Curr Drug Metab 2007, 8:209-216.
    • (2007) Curr Drug Metab , vol.8 , pp. 209-216
    • Fallarino, F.1    Gizzi, S.2    Mosci, P.3
  • 22
    • 70350050540 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in lung allograft tolerance
    • Meloni F., Giuliano S., Solari N., et al. Indoleamine 2,3-dioxygenase in lung allograft tolerance. J Heart Lung Transplant 2009, 28:1185-1192.
    • (2009) J Heart Lung Transplant , vol.28 , pp. 1185-1192
    • Meloni, F.1    Giuliano, S.2    Solari, N.3
  • 23
    • 60949102815 scopus 로고    scopus 로고
    • Suppression of T-cell response and prolongation of allograft survival in a rat model by tryptophan catabolites
    • Dai X., Zhu B.T. Suppression of T-cell response and prolongation of allograft survival in a rat model by tryptophan catabolites. Eur J Pharmacol 2009, 606:225-232.
    • (2009) Eur J Pharmacol , vol.606 , pp. 225-232
    • Dai, X.1    Zhu, B.T.2
  • 24
    • 48949120142 scopus 로고    scopus 로고
    • Gene delivery of indoleamine 2,3-dioxygenase prolongs cardiac allograft survival by shaping the types of T-cell responses
    • Yu G., Dai H., Chen J., et al. Gene delivery of indoleamine 2,3-dioxygenase prolongs cardiac allograft survival by shaping the types of T-cell responses. J Gene Med 2008, 10:754-761.
    • (2008) J Gene Med , vol.10 , pp. 754-761
    • Yu, G.1    Dai, H.2    Chen, J.3
  • 25
    • 36849005119 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival
    • Li J., Meinhardt A., Roehrich M.E., et al. Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival. Am J Physiol Heart Circ Physiol 2007, 293:H3415-H3423.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Li, J.1    Meinhardt, A.2    Roehrich, M.E.3
  • 26
    • 37349119327 scopus 로고    scopus 로고
    • Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats
    • Hill M., Zagani R., Voisine C., et al. Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats. Transplantation 2007, 84:1060-1063.
    • (2007) Transplantation , vol.84 , pp. 1060-1063
    • Hill, M.1    Zagani, R.2    Voisine, C.3
  • 27
    • 1642495750 scopus 로고    scopus 로고
    • Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition
    • Pillarisetty V.G., Shah A.B., Miller G., et al. Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition. J Immunol 2004, 172:1009-1017.
    • (2004) J Immunol , vol.172 , pp. 1009-1017
    • Pillarisetty, V.G.1    Shah, A.B.2    Miller, G.3
  • 28
    • 67349155841 scopus 로고    scopus 로고
    • Overexpression of indoleamine dioxygenase in rat liver allografts using a high-efficiency adeno-associated virus vector does not prevent acute rejection
    • Laurence J.M., Wang C., Zheng M., et al. Overexpression of indoleamine dioxygenase in rat liver allografts using a high-efficiency adeno-associated virus vector does not prevent acute rejection. Liver Transpl 2009, 15:233-241.
    • (2009) Liver Transpl , vol.15 , pp. 233-241
    • Laurence, J.M.1    Wang, C.2    Zheng, M.3
  • 29
    • 47649090897 scopus 로고    scopus 로고
    • Immunological role of indoleamine 2,3-dioxygenase in rat liver allograft rejection and tolerance
    • Lin Y.C., Chen C.L., Nakano T., et al. Immunological role of indoleamine 2,3-dioxygenase in rat liver allograft rejection and tolerance. J Gastroenterol Hepatol 2008, 23(7 Pt 2):e243-e250.
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.7 PART 2
    • Lin, Y.C.1    Chen, C.L.2    Nakano, T.3
  • 30
    • 33845694341 scopus 로고    scopus 로고
    • Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation
    • Brandacher G., Cakar F., Winkler C., et al. Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation. Kidney Int 2007, 71:60-70.
    • (2007) Kidney Int , vol.71 , pp. 60-70
    • Brandacher, G.1    Cakar, F.2    Winkler, C.3
  • 31
    • 49149099012 scopus 로고    scopus 로고
    • Spontaneous renal allograft acceptance associated with "regulatory" dendritic cells and IDO
    • Cook C.H., Bickerstaff A.A., Wang J.J., et al. Spontaneous renal allograft acceptance associated with "regulatory" dendritic cells and IDO. J Immunol 2008, 180:3103-3112.
    • (2008) J Immunol , vol.180 , pp. 3103-3112
    • Cook, C.H.1    Bickerstaff, A.A.2    Wang, J.J.3
  • 32
    • 0035501023 scopus 로고    scopus 로고
    • Murine renal allografts: spontaneous acceptance is associated with regulated T cell-mediated immunity
    • Bickerstaff A.A., Wang J.J., Pelletier R.P., et al. Murine renal allografts: spontaneous acceptance is associated with regulated T cell-mediated immunity. J Immunol 2001, 167:4821-4827.
    • (2001) J Immunol , vol.167 , pp. 4821-4827
    • Bickerstaff, A.A.1    Wang, J.J.2    Pelletier, R.P.3
  • 33
    • 33646046224 scopus 로고    scopus 로고
    • Dominant tolerance to kidney allografts induced by anti-donor MHC class II antibodies: cooperation between T and non-T CD103+ cells
    • Degauque N., Lair D., Dupont A., et al. Dominant tolerance to kidney allografts induced by anti-donor MHC class II antibodies: cooperation between T and non-T CD103+ cells. J Immunol 2006, 176:3915-3922.
    • (2006) J Immunol , vol.176 , pp. 3915-3922
    • Degauque, N.1    Lair, D.2    Dupont, A.3
  • 34
    • 0028234261 scopus 로고
    • In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice
    • Blazar B.R., Taylor P.A., Linsley P.S., et al. In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice. Blood 1994, 83:3815-3825.
    • (1994) Blood , vol.83 , pp. 3815-3825
    • Blazar, B.R.1    Taylor, P.A.2    Linsley, P.S.3
  • 35
    • 0034192104 scopus 로고    scopus 로고
    • CD28-specific antibody prevents graft-versus-host disease in mice
    • Yu X.Z., Bidwell S.J., Martin P.J., et al. CD28-specific antibody prevents graft-versus-host disease in mice. J Immunol 2000, 164:4564-4568.
    • (2000) J Immunol , vol.164 , pp. 4564-4568
    • Yu, X.Z.1    Bidwell, S.J.2    Martin, P.J.3
  • 36
    • 14944346738 scopus 로고    scopus 로고
    • Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
    • Ermann J., Hoffmann P., Edinger M., et al. Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood 2005, 105:2220-2226.
    • (2005) Blood , vol.105 , pp. 2220-2226
    • Ermann, J.1    Hoffmann, P.2    Edinger, M.3
  • 37
    • 34347382735 scopus 로고    scopus 로고
    • The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia
    • Chakraverty R., Sykes M. The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia. Blood 2007, 110:9-17.
    • (2007) Blood , vol.110 , pp. 9-17
    • Chakraverty, R.1    Sykes, M.2
  • 38
    • 42449097698 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality
    • Jasperson L.K., Bucher C., Panoskaltsis-Mortari A., et al. Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality. Blood 2008, 111:3257-3265.
    • (2008) Blood , vol.111 , pp. 3257-3265
    • Jasperson, L.K.1    Bucher, C.2    Panoskaltsis-Mortari, A.3
  • 39
    • 73949103808 scopus 로고    scopus 로고
    • Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
    • Jasperson L.K., Bucher C., Panoskaltsis-Mortari A., et al. Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood 2009, 114:5062-5070.
    • (2009) Blood , vol.114 , pp. 5062-5070
    • Jasperson, L.K.1    Bucher, C.2    Panoskaltsis-Mortari, A.3
  • 40
    • 45449098695 scopus 로고    scopus 로고
    • Composite tissue transplantation: a rapidly advancing field
    • Ravindra K.V., Wu S., Bozulic L., et al. Composite tissue transplantation: a rapidly advancing field. Transplant Proc 2008, 40:1237-1248.
    • (2008) Transplant Proc , vol.40 , pp. 1237-1248
    • Ravindra, K.V.1    Wu, S.2    Bozulic, L.3
  • 41
    • 0033577486 scopus 로고    scopus 로고
    • Human hand allograft: report on first 6 months
    • Dubernard J.M., Owen E., Herzberg G., et al. Human hand allograft: report on first 6 months. Lancet 1999, 353:1315-1320.
    • (1999) Lancet , vol.353 , pp. 1315-1320
    • Dubernard, J.M.1    Owen, E.2    Herzberg, G.3
  • 43
    • 35348995546 scopus 로고    scopus 로고
    • "Facial graft": about the first facial allotransplantation of composite tissues
    • Lengele B.G., Testelin S., Dakpe S., et al. "Facial graft": about the first facial allotransplantation of composite tissues. Ann Chir Plast Esthet 2007, 52:457-484.
    • (2007) Ann Chir Plast Esthet , vol.52 , pp. 457-484
    • Lengele, B.G.1    Testelin, S.2    Dakpe, S.3
  • 44
    • 33745828140 scopus 로고    scopus 로고
    • First human face allograft: early report
    • Devauchelle B., Badet L., Lengele B., et al. First human face allograft: early report. Lancet 2006, 368:203-209.
    • (2006) Lancet , vol.368 , pp. 203-209
    • Devauchelle, B.1    Badet, L.2    Lengele, B.3
  • 45
    • 35348966369 scopus 로고    scopus 로고
    • Mediatisation and "facial graft" or "to whom belongs the facial graft"?
    • Devauchelle B., Lengele B.G., Moure C., et al. Mediatisation and "facial graft" or "to whom belongs the facial graft"?. Ann Chir Plast Esthet 2007, 52:528-530.
    • (2007) Ann Chir Plast Esthet , vol.52 , pp. 528-530
    • Devauchelle, B.1    Lengele, B.G.2    Moure, C.3
  • 46
    • 33845941704 scopus 로고    scopus 로고
    • Isolation of regulatory T cells in the skin of a human hand-allograft, up to six years posttransplantation
    • Eljaafari A., Badet L., Kanitakis J., et al. Isolation of regulatory T cells in the skin of a human hand-allograft, up to six years posttransplantation. Transplantation 2006, 82:1746-1748.
    • (2006) Transplantation , vol.82 , pp. 1746-1748
    • Eljaafari, A.1    Badet, L.2    Kanitakis, J.3
  • 47
    • 62849086405 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and foxp3 expression in skin rejection of human hand allografts
    • Hautz T., Brandacher G., Zelger B., et al. Indoleamine 2,3-dioxygenase and foxp3 expression in skin rejection of human hand allografts. Transplant Proc 2009, 41:509-512.
    • (2009) Transplant Proc , vol.41 , pp. 509-512
    • Hautz, T.1    Brandacher, G.2    Zelger, B.3
  • 48
    • 36348989013 scopus 로고    scopus 로고
    • Steady state dendritic cells with forced IDO expression induce skin allograft tolerance by upregulation of regulatory T cells
    • Yu G., Fang M., Gong M., et al. Steady state dendritic cells with forced IDO expression induce skin allograft tolerance by upregulation of regulatory T cells. Transpl Immunol 2008, 18:208-219.
    • (2008) Transpl Immunol , vol.18 , pp. 208-219
    • Yu, G.1    Fang, M.2    Gong, M.3
  • 49
    • 54049151564 scopus 로고    scopus 로고
    • The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation
    • Chen W., Liang X., Peterson A.J., et al. The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation. J Immunol 2008, 181:5396-5404.
    • (2008) J Immunol , vol.181 , pp. 5396-5404
    • Chen, W.1    Liang, X.2    Peterson, A.J.3
  • 50
    • 0036852170 scopus 로고    scopus 로고
    • CTLA-4-Ig regulates tryptophan catabolism in vivo
    • Grohmann U., Orabona C., Fallarino F., et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 2002, 3:1097-1101.
    • (2002) Nat Immunol , vol.3 , pp. 1097-1101
    • Grohmann, U.1    Orabona, C.2    Fallarino, F.3
  • 51
    • 32844455802 scopus 로고    scopus 로고
    • Contrasting CD25hiCD4+T cells/FOXP3 patterns in chronic rejection and operational drug-free tolerance
    • Louis S., Braudeau C., Giral M., et al. Contrasting CD25hiCD4+T cells/FOXP3 patterns in chronic rejection and operational drug-free tolerance. Transplantation 2006, 81:398-407.
    • (2006) Transplantation , vol.81 , pp. 398-407
    • Louis, S.1    Braudeau, C.2    Giral, M.3


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