Immunological role of indoleamine 2,3-dioxygenase in rat liver allograft rejection and tolerance

Journal of Gastroenterology and Hepatology (Australia)

Volumn 23, Issue 7 PT2, 2008, Pages

  Lin, Yu Chun ^a,d   Chen, Chao Long ^d   Nakano, Toshiaki ^d   Goto, Shigeru ^c,d   Kao, Ying Hsien ^d   Hsu, Li Wen ^d   Lai, Chia Yun ^d   Jawan, Bruno ^d   Cheng, Yu Fan ^d   Tateno, Chise ^b   Yoshizato, Katsutoshi ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c Iwao Hospital   (Japan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Indoleamine 2,3 dioxygenase; Liver transplantation; Parenchymal cell; Rejection; Tolerance

Indexed keywords

CYCLOSPORIN A; INDOLEAMINE 2,3 DIOXYGENASE; MESSENGER RNA;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; GENE; GENE EXPRESSION; GENETIC ANALYSIS; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; INDOLEAMINE 2,3 DIOXYGENASE GENE; LIVER CELL; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 47649090897     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2007.05036.x     Document Type: Article

References (47)

1. Calne RY, Sells RA, Pena JR et al. Induction of immunological tolerance by porcine liver allografts. Nature 1969 223 : 472 6.
2. Kamada N, Davies HS, Roser B. Reversal of transplantation immunity by liver grafting. Nature 1981 292 : 840 2.
3. Kamada N, Brons G, Davies HS. Fully allogeneic liver grafting in rats induces a state of systemic nonreactivity to donor transplantation antigens. Transplantation 1980 29 : 429 31.
4. Davies HS, Pollard SG, Calne RY. Soluble HLA antigens in the circulation of liver graft recipients. Transplantation 1989 47 : 524 7.
5. Zavazava N, Kronke M. Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Nat. Med. 1996 2 : 1005 10.
6. Qian S, Lu L, Fu F et al. Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction. J. Immunol. 1997 158 : 4654 61.
7. Bertolino P, Trescol-Biemont MC, Thomas J et al. Death by neglect as a deletional mechanism of peripheral tolerance. Int. Immunol. 1999 11 : 1225 38.
8. Celli S, Matzinger P. Liver transplants induce deletion of liver-specific T cells. Transplant. Proc. 2001 33 : 102 3.
9. Kamada N. The immunology of experimental liver transplantation in the rat. Immunology 1985 55 : 369 89.
10. Kobayashi E, Kamada N, Enosawa S et al. Prevention by liver transplantation of the graft-versus-host reaction and allograft rejection in a rat model of small bowel transplantation. Transplantation 1994 57 : 177 81.
11. Tsurufuji M, Ishiguro K, Shinomiya T, Uchida T, Kamada N. Immunosuppressive activity of serum from liver-grafted rats: in vitro specific inhibition of mixed lymphocyte reactivity by antibodies against class II RT1 alloantigens. Immunology 1987 61 : 421 8.
12. Sun J, Sheil AG, Wang C et al. Tolerance to rat liver allografts: IV. Acceptance depends on the quantity of donor tissue and on donor leukocytes. Transplantation 1996 62 : 1725 30.
13. Otto C, Kauczok J, Martens N et al. Mechanisms of tolerance induction after rat liver transplantation: intrahepatic CD4(+) T cells produce different cytokines during rejection and tolerance in response to stimulation. J. Gastrointest. Surg. 2002 6 : 455 63.
14. Sun Z, Wada T, Maemura K et al. Hepatic allograft-derived Kupffer cells regulate T cell response in rats. Liver Transpl. 2003 9 : 489 97.
15. Olver S, Goto S, Chiba S, Clouston A, Kelso A. Persistence of donor-reactive CD4+ T cells in liver and spleen of rats tolerant to a liver allograft. Transplantation 1998 66 : 132 5.
16. Starzl TE, Murase N, Thomson A, Demetris AJ. Liver transplants contribute to their own success. Nat. Med. 1996 2 : 163 5.
17. Ricordi C, Karatzas T, Nery J et al. High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing. Transplantation 1997 63 : 7 11.
18. Thomson AW, Lu L, Murase N et al. Microchimerism, dendritic cell progenitors and transplantation tolerance. Stem Cells 1995 13 : 622 39.
19. Starzl TE, Demetris AJ, Murase N et al. Cell migration, chimerism, and graft acceptance. Lancet 1992 339 : 1579 82.
20. Lord R, Vari F, Goto S, Sunagawa M. Antigen presenting cells and chimerism. Transpl. Immunol. 1998 6 : 61 3.
21. Kamada N, Goto S, Lord R, Kobayashi E, Kim YI. Novel immunosuppressive proteins induced in rats by liver retransplantation. Transplant. Proc. 1995 27 : 402 3.
22. Bishop GA, Sun J, DeCruz DJ et al. Tolerance to rat liver allografts. III. Donor cell migration and tolerance-associated cytokine production in peripheral lymphoid tissues. J. Immunol. 1996 156 : 4925 31.
23. Kobayashi S, Lord R, Goto S et al. Production of IL-2 by hepatocytes in allografted liver of rats. Transpl. Immunol. 1997 5 : 237 9.
24. Moffett-King A. Natural killer cells and pregnancy. Nat. Rev. Immunol. 2002 2 : 656 63.
25. Munn DH, Zhou M, Attwood JT et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998 281 : 1191 3.
26. Munn DH, Shafizadeh E, Attwood JT et al. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J. Exp. Med. 1999 189 : 1363 72.
27. Hwu P, Du MX, Lapointe R et al. Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation. J. Immunol. 2000 164 : 3596 9.
28. Kai S, Goto S, Tahara K et al. Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth. J. Exp. Ther. Oncol. 2003 3 : 336 45.
29. Kai S, Goto S, Tahara K et al. Indoleamine 2,3-dioxygenase is necessary for cytolytic activity of natural killer cells. Scand. J. Immunol. 2004 59 : 177 82.
30. Alexander AM, Crawford M, Bertera S et al. Indoleamine 2,3-dioxygenase expression in transplanted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes 2002 51 : 356 65.
31. Li Y, Tredget EE, Ghaffari A et al. Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute. J. Invest. Dermatol. 2006 126 : 128 36.
32. Liu H, Liu L, Fletcher BS, Visner GA. Novel action of indoleamine 2,3-dioxygenase attenuating acute lung allograft injury. Am. J. Respir. Crit. Care Med. 2006 173 : 566 72.
33. Beutelspacher SC, Pillai R, Watson MP et al. Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. Eur. J. Immunol. 2006 36 : 690 700.
34. Miki T, Sun H, Lee Y et al. Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts. Transplant. Proc. 2001 33 : 129 30.
35. Pan TL, Lin CL, Chen CL et al. Identification of the indoleamine 2,3-dioxygenase nucleotide sequence in a rat liver transplant model. Transpl. Immunol. 2000 8 : 189 94.
36. Nakano T, Kawamoto S, Lai CY et al. Liver transplantation-induced antihistone H1 autoantibodies suppress mixed lymphocyte reaction. Transplantation 2004 77 : 1595 603.
37. Kamada N, Calne RY. A surgical experience with five hundred thirty liver transplants in the rat. Surgery 1983 93 : 64 9.
38. Lord R, Goto S, Vari F et al. Differences in the rate of donor leucocyte migration between natural and drug-assisted tolerance following rat liver transplantation. Clin. Exp. Immunol. 1997 108 : 358 65.
39. Tateno C, Takai-Kajihara K, Yamasaki C, Sato H, Yoshizato K. Heterogeneity of growth potential of adult rat hepatocytes in vitro. Hepatology 2000 31 : 65 74.
40. Terness P, Bauer TM, Rose L et al. Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites. J. Exp. Med. 2002 196 : 447 57.
41. Fallarino F, Grohmann U, Vacca C et al. T cell apoptosis by kynurenines. Adv. Exp. Med. Biol. 2003 527 : 183 90.
42. Damoiseaux JG, Dopp EA, Calame W et al. Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. Immunology 1994 83 : 140 7.
43. Dijkstra CD, Dopp EA, Joling P, Kraal G. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 1985 54 : 589 99.
44. Bauer TM, Jiga LP, Chuang JJ et al. Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo. Transpl. Int. 2005 18 : 95 100.
45. Laurence JM, Wang C, Park T et al. The role of tryptophan metabolism in rat liver transplant tolerance. Transplantation 2006 82 : 889.
46. Munn DH, Sharma MD, Lee JR et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 2002 297 : 1867 70.
47. Grohmann U, Fallarino F, Puccetti P. Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol. 2003 24 : 242 8.