-
1
-
-
0842300373
-
Steatosis and hepatitis C virus: mechanisms and significance for hepatic and extrahepatic disease
-
Lonardo A, Adinolfi LE, Loria P, Carulli N, Ruggiero G, Day CP. Steatosis and hepatitis C virus: mechanisms and significance for hepatic and extrahepatic disease. Gastroenterology 2004, 126:586-97.
-
(2004)
Gastroenterology
, vol.126
, pp. 586-597
-
-
Lonardo, A.1
Adinolfi, L.E.2
Loria, P.3
Carulli, N.4
Ruggiero, G.5
Day, C.P.6
-
2
-
-
37849038662
-
Combination of oxidative stress and steatosis is a risk factor for fibrosis in alcohol-drinking patients with chronic hepatitis C
-
Vidali M, Occhino G, Ivaldi A, Rigamonti C, Sartori M, Albano E. Combination of oxidative stress and steatosis is a risk factor for fibrosis in alcohol-drinking patients with chronic hepatitis C. Am J Gastroenterol 2008, 103:147-53.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 147-153
-
-
Vidali, M.1
Occhino, G.2
Ivaldi, A.3
Rigamonti, C.4
Sartori, M.5
Albano, E.6
-
3
-
-
0034997875
-
Outcome of liver disease in a large cohort of histologically proven chronic hepatitis C: influence of HCV genotype
-
Roffi L, Redaelli A, Colloredo G. Outcome of liver disease in a large cohort of histologically proven chronic hepatitis C: influence of HCV genotype. Eur J Gastroenterol Hepatol 2001, 13:501-6.
-
(2001)
Eur J Gastroenterol Hepatol
, vol.13
, pp. 501-506
-
-
Roffi, L.1
Redaelli, A.2
Colloredo, G.3
-
4
-
-
0036727323
-
Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcohol
-
Monto A, Alonzo J, Watson JJ, Grunfeld C, Wright TL. Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcohol. Hepatology 2002, 36:729-36.
-
(2002)
Hepatology
, vol.36
, pp. 729-736
-
-
Monto, A.1
Alonzo, J.2
Watson, J.J.3
Grunfeld, C.4
Wright, T.L.5
-
5
-
-
0345017776
-
Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes
-
Aytug S, Reich D, Sapiro LE, Bernstein D, Begum N. Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes. Hepatology 2003, 38:1384-92.
-
(2003)
Hepatology
, vol.38
, pp. 1384-1392
-
-
Aytug, S.1
Reich, D.2
Sapiro, L.E.3
Bernstein, D.4
Begum, N.5
-
6
-
-
7244243810
-
Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
-
Kawaguchi T, Yoshida T, Harada M. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3. Am J Pathol 2004, 165:1499-508.
-
(2004)
Am J Pathol
, vol.165
, pp. 1499-1508
-
-
Kawaguchi, T.1
Yoshida, T.2
Harada, M.3
-
7
-
-
21044456174
-
Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C
-
Fartoux L, Poujol-Robert A, Guechot J, Wendum D, Poupon R, Serfaty L. Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C. Gut 2005, 54:1003-8.
-
(2005)
Gut
, vol.54
, pp. 1003-1008
-
-
Fartoux, L.1
Poujol-Robert, A.2
Guechot, J.3
Wendum, D.4
Poupon, R.5
Serfaty, L.6
-
8
-
-
0346874154
-
In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy
-
Hickman IJ, Powell EE, Prins JB. In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy. J Hepatol 2003, 39:1042-8.
-
(2003)
J Hepatol
, vol.39
, pp. 1042-1048
-
-
Hickman, I.J.1
Powell, E.E.2
Prins, J.B.3
-
9
-
-
33845990292
-
Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2?
-
van Dam RM, Hu FB. Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2? Clin Chem 2007, 53:5-7.
-
(2007)
Clin Chem
, vol.53
, pp. 5-7
-
-
van Dam, R.M.1
Hu, F.B.2
-
10
-
-
30444461216
-
Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat?
-
Larter CZ, Farrell GC. Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat? J Hepatol 2006, 44:253-61.
-
(2006)
J Hepatol
, vol.44
, pp. 253-261
-
-
Larter, C.Z.1
Farrell, G.C.2
-
11
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
Graham TE, Yang Q, Bluher M. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 2006, 354:2552-63.
-
(2006)
N Engl J Med
, vol.354
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Bluher, M.3
-
12
-
-
84984586017
-
Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C
-
Liu CJ, Chen PJ, Jeng YM. Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C. J Hepatol 2005, 43:235-42.
-
(2005)
J Hepatol
, vol.43
, pp. 235-242
-
-
Liu, C.J.1
Chen, P.J.2
Jeng, Y.M.3
-
13
-
-
47149104844
-
Retinol-binding protein 4: a new marker of virus-induced steatosis in patients infected with hepatitis c virus genotype 1
-
Petta S, Camma C, Di Marco V. Retinol-binding protein 4: a new marker of virus-induced steatosis in patients infected with hepatitis c virus genotype 1. Hepatology 2008, 48:28-37.
-
(2008)
Hepatology
, vol.48
, pp. 28-37
-
-
Petta, S.1
Camma, C.2
Di Marco, V.3
-
14
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
Feldstein AE, Canbay A, Angulo P. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003, 125:437-43.
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
-
15
-
-
0348134733
-
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
-
Feldstein AE, Canbay A, Guicciardi ME, Higuchi H, Bronk SF, Gores GJ. Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J Hepatol 2003, 39:978-83.
-
(2003)
J Hepatol
, vol.39
, pp. 978-983
-
-
Feldstein, A.E.1
Canbay, A.2
Guicciardi, M.E.3
Higuchi, H.4
Bronk, S.F.5
Gores, G.J.6
-
16
-
-
12144289459
-
Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches
-
Ballesteros AL, Franco S, Fuster D. Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches. Aids 2004, 18:59-66.
-
(2004)
Aids
, vol.18
, pp. 59-66
-
-
Ballesteros, A.L.1
Franco, S.2
Fuster, D.3
-
17
-
-
17844385292
-
Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients
-
Adinolfi LE, Ingrosso D, Cesaro G. Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients. Hepatology 2005, 41:995-1003.
-
(2005)
Hepatology
, vol.41
, pp. 995-1003
-
-
Adinolfi, L.E.1
Ingrosso, D.2
Cesaro, G.3
-
18
-
-
0034987263
-
Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
-
Adinolfi LE, Gambardella M, Andreana A, Tripodi MF, Utili R, Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001, 33:1358-64.
-
(2001)
Hepatology
, vol.33
, pp. 1358-1364
-
-
Adinolfi, L.E.1
Gambardella, M.2
Andreana, A.3
Tripodi, M.F.4
Utili, R.5
Ruggiero, G.6
-
19
-
-
0033933140
-
Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3
-
Rubbia-Brandt L, Quadri R, Abid K. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 2000, 33:106-15.
-
(2000)
J Hepatol
, vol.33
, pp. 106-115
-
-
Rubbia-Brandt, L.1
Quadri, R.2
Abid, K.3
-
20
-
-
0035572430
-
Liver steatosis in chronic hepatitis C: a morphological sign suggesting infection with HCV genotype 3
-
Rubbia-Brandt L, Leandro G, Spahr L. Liver steatosis in chronic hepatitis C: a morphological sign suggesting infection with HCV genotype 3. Histopathology 2001, 39:119-24.
-
(2001)
Histopathology
, vol.39
, pp. 119-124
-
-
Rubbia-Brandt, L.1
Leandro, G.2
Spahr, L.3
-
21
-
-
0030859121
-
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
-
Moriya K, Yotsuyanagi H, Shintani Y. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 1997, 78:1527-31.
-
(1997)
J Gen Virol
, vol.78
, pp. 1527-1531
-
-
Moriya, K.1
Yotsuyanagi, H.2
Shintani, Y.3
-
22
-
-
0036830436
-
Hepatitis C virus genotype 3 is cytopathic to hepatocytes: Reversal of hepatic steatosis after sustained therapeutic response
-
Kumar D, Farrell GC, Fung C, George J. Hepatitis C virus genotype 3 is cytopathic to hepatocytes: Reversal of hepatic steatosis after sustained therapeutic response. Hepatology 2002, 36:1266-72.
-
(2002)
Hepatology
, vol.36
, pp. 1266-1272
-
-
Kumar, D.1
Farrell, G.C.2
Fung, C.3
George, J.4
-
23
-
-
37649012154
-
Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin
-
Reddy KR, Govindarajan S, Marcellin P. Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin. J Viral Hepat 2008, 15:129-36.
-
(2008)
J Viral Hepat
, vol.15
, pp. 129-136
-
-
Reddy, K.R.1
Govindarajan, S.2
Marcellin, P.3
-
24
-
-
10744224572
-
Effect of antiviral treatment on evolution of liver steatosis in patients with chronic hepatitis C: indirect evidence of a role of hepatitis C virus genotype 3 in steatosis
-
Castera L, Hezode C, Roudot-Thoraval F. Effect of antiviral treatment on evolution of liver steatosis in patients with chronic hepatitis C: indirect evidence of a role of hepatitis C virus genotype 3 in steatosis. Gut 2004, 53:420-4.
-
(2004)
Gut
, vol.53
, pp. 420-424
-
-
Castera, L.1
Hezode, C.2
Roudot-Thoraval, F.3
-
25
-
-
11144357274
-
Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets
-
Barba G, Harper F, Harada T. Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. Proc Natl Acad Sci USA 1997, 94:1200-5.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1200-1205
-
-
Barba, G.1
Harper, F.2
Harada, T.3
-
26
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998, 4:1065-7.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
-
27
-
-
18244365866
-
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis
-
Perlemuter G, Sabile A, Letteron P. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. Faseb J 2002, 16:185-94.
-
(2002)
Faseb J
, vol.16
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
-
28
-
-
47149095922
-
Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis
-
Piodi A, Chouteau P, Lerat H, Hezode C, Pawlotsky JM. Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis. Hepatology 2008, 48:16-27.
-
(2008)
Hepatology
, vol.48
, pp. 16-27
-
-
Piodi, A.1
Chouteau, P.2
Lerat, H.3
Hezode, C.4
Pawlotsky, J.M.5
-
29
-
-
0035068318
-
Hepatitis C virus induced hypobetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C
-
Serfaty L, Andreani T, Giral P, Carbonell N, Chazouilleres O, Poupon R. Hepatitis C virus induced hypobetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C. J Hepatol 2001, 34:428-34.
-
(2001)
J Hepatol
, vol.34
, pp. 428-434
-
-
Serfaty, L.1
Andreani, T.2
Giral, P.3
Carbonell, N.4
Chazouilleres, O.5
Poupon, R.6
-
30
-
-
0026470990
-
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
-
Wetterau JR, Aggerbeck LP, Bouma ME. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science 1992, 258:999-1001.
-
(1992)
Science
, vol.258
, pp. 999-1001
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Bouma, M.E.3
-
31
-
-
18344370950
-
Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity
-
Tsutsumi T, Suzuki T, Shimoike T. Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity. Hepatology 2002, 35:937-46.
-
(2002)
Hepatology
, vol.35
, pp. 937-946
-
-
Tsutsumi, T.1
Suzuki, T.2
Shimoike, T.3
-
32
-
-
23044450214
-
Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver
-
Yamaguchi A, Tazuma S, Nishioka T. Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver. Dig Dis Sci 2005, 50:1361-71.
-
(2005)
Dig Dis Sci
, vol.50
, pp. 1361-1371
-
-
Yamaguchi, A.1
Tazuma, S.2
Nishioka, T.3
-
33
-
-
33644882808
-
Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection
-
de Gottardi A, Pazienza V, Pugnale P. Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection. Aliment Pharmacol Ther 2006, 23:107-14.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 107-114
-
-
de Gottardi, A.1
Pazienza, V.2
Pugnale, P.3
-
34
-
-
31644451456
-
Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor alpha and carnitine palmitoyl acyl-CoA transferase 1A
-
Cheng Y, Dharancy S, Malapel M, Desreumaux P. Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor alpha and carnitine palmitoyl acyl-CoA transferase 1A. World J Gastroenterol 2005, 11:7591-6.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 7591-7596
-
-
Cheng, Y.1
Dharancy, S.2
Malapel, M.3
Desreumaux, P.4
-
35
-
-
77954360765
-
Steatosis and intrahepatic expression levels of genes regulating lipid metabolism in Japanese patients with chronic hepatitis C
-
Yasui KHY, Mitsuyoshi H, Tsuji K. Steatosis and intrahepatic expression levels of genes regulating lipid metabolism in Japanese patients with chronic hepatitis C. Hepatology 2008, 48(4):775A. Suppl
-
(2008)
Hepatology
, vol.48
, Issue.4 SUPPL
-
-
Yasui, K.H.Y.1
Mitsuyoshi, H.2
Tsuji, K.3
-
36
-
-
0028618516
-
Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population
-
Allison ME, Wreghitt T, Palmer CR, Alexander GJ. Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population. J Hepatol 1994, 21:1135-9.
-
(1994)
J Hepatol
, vol.21
, pp. 1135-1139
-
-
Allison, M.E.1
Wreghitt, T.2
Palmer, C.R.3
Alexander, G.J.4
-
37
-
-
0034032877
-
Increased risk of type 2 diabetes in noncirrhotic patients with chronic hepatitis C virus infection
-
Knobler H, Schihmanter R, Zifroni A, Fenakel G, Schattner A. Increased risk of type 2 diabetes in noncirrhotic patients with chronic hepatitis C virus infection. Mayo Clin Proc 2000, 75:355-9.
-
(2000)
Mayo Clin Proc
, vol.75
, pp. 355-359
-
-
Knobler, H.1
Schihmanter, R.2
Zifroni, A.3
Fenakel, G.4
Schattner, A.5
-
38
-
-
0033779703
-
Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States
-
Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Ann Intern Med 2000, 133:592-9.
-
(2000)
Ann Intern Med
, vol.133
, pp. 592-599
-
-
Mehta, S.H.1
Brancati, F.L.2
Sulkowski, M.S.3
Strathdee, S.A.4
Szklo, M.5
Thomas, D.L.6
-
39
-
-
13744254182
-
Chronic hepatitis C and type II diabetes mellitus: a prospective cross-sectional study
-
Zein CO, Levy C, Basu A, Zein NN. Chronic hepatitis C and type II diabetes mellitus: a prospective cross-sectional study. Am J Gastroenterol 2005, 100:48-55.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 48-55
-
-
Zein, C.O.1
Levy, C.2
Basu, A.3
Zein, N.N.4
-
40
-
-
0037282977
-
Association between hepatitis C, diabetes mellitus, and race. a case-control study
-
Thuluvath PJ, John PR. Association between hepatitis C, diabetes mellitus, and race. a case-control study. Am J Gastroenterol 2003, 98:438-41.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 438-441
-
-
Thuluvath, P.J.1
John, P.R.2
-
41
-
-
53249121480
-
Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis
-
White DL, Ratziu V, El-Serag HB. Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis. J Hepatol 2008, 49:831-44.
-
(2008)
J Hepatol
, vol.49
, pp. 831-844
-
-
White, D.L.1
Ratziu, V.2
El-Serag, H.B.3
-
42
-
-
0345655291
-
Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected
-
Hui JM, Sud A, Farrell GC. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected. Gastroenterology 2003, 125:1695-704.
-
(2003)
Gastroenterology
, vol.125
, pp. 1695-1704
-
-
Hui, J.M.1
Sud, A.2
Farrell, G.C.3
-
43
-
-
77954358029
-
Serum hepcidin levels are related to viral load and to histological severity of liver lesions in chronic hepatitis C
-
Tsochatzis EPG, Koliaraki V, Manesis EK, Mamalaki A, Archimandritis AJ. Serum hepcidin levels are related to viral load and to histological severity of liver lesions in chronic hepatitis C. Hepatology 2008, 48:774A.
-
(2008)
Hepatology
, vol.48
-
-
Tsochatzis, E.P.G.1
Koliaraki, V.2
Manesis, E.K.3
Mamalaki, A.4
Archimandritis, A.J.5
-
44
-
-
0031055840
-
Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype
-
Mihm S, Fayyazi A, Hartmann H, Ramadori G. Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype. Hepatology 1997, 25:735-9.
-
(1997)
Hepatology
, vol.25
, pp. 735-739
-
-
Mihm, S.1
Fayyazi, A.2
Hartmann, H.3
Ramadori, G.4
-
45
-
-
10744220759
-
Liver fibrosis is not associated with steatosis but with necroinflammation in French patients with chronic hepatitis C
-
Asselah T, Boyer N, Guimont MC. Liver fibrosis is not associated with steatosis but with necroinflammation in French patients with chronic hepatitis C. Gut 2003, 52:1638-43.
-
(2003)
Gut
, vol.52
, pp. 1638-1643
-
-
Asselah, T.1
Boyer, N.2
Guimont, M.C.3
-
46
-
-
0141757418
-
Worsening of steatosis and fibrosis progression in hepatitis C
-
Castera L, Pawlotsky JM, Dhumeaux D. Worsening of steatosis and fibrosis progression in hepatitis C. Gut 2003, 52:1531.
-
(2003)
Gut
, vol.52
, pp. 1531
-
-
Castera, L.1
Pawlotsky, J.M.2
Dhumeaux, D.3
-
47
-
-
0038122773
-
Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C
-
Poynard T, Ratziu V, McHutchison J. Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C. Hepatology 2003, 38:75-85.
-
(2003)
Hepatology
, vol.38
, pp. 75-85
-
-
Poynard, T.1
Ratziu, V.2
McHutchison, J.3
-
48
-
-
10744227418
-
The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients
-
Patton HM, Patel K, Behling C. The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol 2004, 40:484-90.
-
(2004)
J Hepatol
, vol.40
, pp. 484-490
-
-
Patton, H.M.1
Patel, K.2
Behling, C.3
-
49
-
-
10744224920
-
Steatosis affects chronic hepatitis C progression in a genotype specific way
-
Rubbia-Brandt L, Fabris P, Paganin S. Steatosis affects chronic hepatitis C progression in a genotype specific way. Gut 2004, 53:406-12.
-
(2004)
Gut
, vol.53
, pp. 406-412
-
-
Rubbia-Brandt, L.1
Fabris, P.2
Paganin, S.3
-
50
-
-
77953987260
-
Prospective Comparison of Fibroscan, King's Score and Liver Biopsy for the Assessment of Cirrhosis in Chronic Hepatitis C infection
-
Cross TJ, Calvaruso V, Maimone S. Prospective Comparison of Fibroscan, King's Score and Liver Biopsy for the Assessment of Cirrhosis in Chronic Hepatitis C infection. J Viral Hepat 2009
-
(2009)
J Viral Hepat
-
-
Cross, T.J.1
Calvaruso, V.2
Maimone, S.3
-
51
-
-
67651139900
-
Evolution of hepatic steatosis in patients with advanced hepatitis C: results from the hepatitis C antiviral long-term treatment against cirrhosis (HALT-C) trial
-
Lok AS, Everhart JE, Chung RT. Evolution of hepatic steatosis in patients with advanced hepatitis C: results from the hepatitis C antiviral long-term treatment against cirrhosis (HALT-C) trial. Hepatology 2009, 49:1828-37.
-
(2009)
Hepatology
, vol.49
, pp. 1828-1837
-
-
Lok, A.S.1
Everhart, J.E.2
Chung, R.T.3
-
52
-
-
0032146915
-
Host- and disease-specific factors affecting steatosis in chronic hepatitis C
-
Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Host- and disease-specific factors affecting steatosis in chronic hepatitis C. J Hepatol 1998, 29:198-206.
-
(1998)
J Hepatol
, vol.29
, pp. 198-206
-
-
Czaja, A.J.1
Carpenter, H.A.2
Santrach, P.J.3
Moore, S.B.4
-
53
-
-
0036381117
-
Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection
-
Hui JM, Kench J, Farrell GC. Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection. J Gastroenterol Hepatol 2002, 17:873-81.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 873-881
-
-
Hui, J.M.1
Kench, J.2
Farrell, G.C.3
-
54
-
-
29244484291
-
Steatosis in chronic hepatitis C: why does it really matter?
-
Asselah T, Rubbia-Brandt L, Marcellin P, Negro F. Steatosis in chronic hepatitis C: why does it really matter? Gut 2006, 55:123-30.
-
(2006)
Gut
, vol.55
, pp. 123-130
-
-
Asselah, T.1
Rubbia-Brandt, L.2
Marcellin, P.3
Negro, F.4
-
55
-
-
38649120719
-
Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis
-
Moucari R, Asselah T, Cazals-Hatem D. Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis. Gastroenterology 2008, 134:416-23.
-
(2008)
Gastroenterology
, vol.134
, pp. 416-423
-
-
Moucari, R.1
Asselah, T.2
Cazals-Hatem, D.3
-
56
-
-
33646529840
-
Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data
-
Leandro G, Mangia A, Hui J. Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data. Gastroenterology 2006, 130:1636-42.
-
(2006)
Gastroenterology
, vol.130
, pp. 1636-1642
-
-
Leandro, G.1
Mangia, A.2
Hui, J.3
-
57
-
-
0036294003
-
Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C
-
Hickman IJ, Clouston AD, Macdonald GA. Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C. Gut 2002, 51:89-94.
-
(2002)
Gut
, vol.51
, pp. 89-94
-
-
Hickman, I.J.1
Clouston, A.D.2
Macdonald, G.A.3
-
58
-
-
0035117297
-
Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation
-
Clouston AD, Jonsson JR, Purdie DM. Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation. J Hepatol 2001, 34:314-20.
-
(2001)
J Hepatol
, vol.34
, pp. 314-320
-
-
Clouston, A.D.1
Jonsson, J.R.2
Purdie, D.M.3
-
59
-
-
0001513966
-
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis
-
Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 1997, 94:2557-62.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2557-2562
-
-
Yang, S.Q.1
Lin, H.Z.2
Lane, M.D.3
Clemens, M.4
Diehl, A.M.5
-
60
-
-
0036165333
-
Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
-
Okuda M, Li K, Beard MR. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002, 122:366-75.
-
(2002)
Gastroenterology
, vol.122
, pp. 366-375
-
-
Okuda, M.1
Li, K.2
Beard, M.R.3
-
61
-
-
8544254757
-
In situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features
-
Paradis V, Mathurin P, Kollinger M. In situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features. J Clin Pathol 1997, 50:401-6.
-
(1997)
J Clin Pathol
, vol.50
, pp. 401-406
-
-
Paradis, V.1
Mathurin, P.2
Kollinger, M.3
-
62
-
-
0030854425
-
A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C
-
Houglum K, Venkataramani A, Lyche K, Chojkier M. A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C. Gastroenterology 1997, 113:1069-73.
-
(1997)
Gastroenterology
, vol.113
, pp. 1069-1073
-
-
Houglum, K.1
Venkataramani, A.2
Lyche, K.3
Chojkier, M.4
-
63
-
-
0029165057
-
Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
-
Teli MR, Day CP, Burt AD, Bennett MK, James OF. Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 1995, 346:987-90.
-
(1995)
Lancet
, vol.346
, pp. 987-990
-
-
Teli, M.R.1
Day, C.P.2
Burt, A.D.3
Bennett, M.K.4
James, O.F.5
-
65
-
-
0348134685
-
Fibrogenic impact of high serum glucose in chronic hepatitis C
-
Ratziu V, Munteanu M, Charlotte F, Bonyhay L, Poynard T. Fibrogenic impact of high serum glucose in chronic hepatitis C. J Hepatol 2003, 39:1049-55.
-
(2003)
J Hepatol
, vol.39
, pp. 1049-1055
-
-
Ratziu, V.1
Munteanu, M.2
Charlotte, F.3
Bonyhay, L.4
Poynard, T.5
-
66
-
-
0036185832
-
Risk factors of fibrosis in alcohol-induced liver disease
-
Raynard B, Balian A, Fallik D. Risk factors of fibrosis in alcohol-induced liver disease. Hepatology 2002, 35:635-8.
-
(2002)
Hepatology
, vol.35
, pp. 635-638
-
-
Raynard, B.1
Balian, A.2
Fallik, D.3
-
67
-
-
1542287381
-
Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance
-
Shintani Y, Fujie H, Miyoshi H. Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance. Gastroenterology 2004, 126:840-8.
-
(2004)
Gastroenterology
, vol.126
, pp. 840-848
-
-
Shintani, Y.1
Fujie, H.2
Miyoshi, H.3
-
68
-
-
0030052322
-
Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C
-
Larrea E, Garcia N, Qian C, Civeira MP, Prieto J. Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C. Hepatology 1996, 23:210-17.
-
(1996)
Hepatology
, vol.23
, pp. 210-217
-
-
Larrea, E.1
Garcia, N.2
Qian, C.3
Civeira, M.P.4
Prieto, J.5
-
69
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997, 389:610-14.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
70
-
-
0035034309
-
Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells
-
Halse R, Pearson SL, McCormack JG, Yeaman SJ, Taylor R. Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells. Diabetes 2001, 50:1102-9.
-
(2001)
Diabetes
, vol.50
, pp. 1102-1109
-
-
Halse, R.1
Pearson, S.L.2
McCormack, J.G.3
Yeaman, S.J.4
Taylor, R.5
-
71
-
-
0034802171
-
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
-
Paradis V, Perlemuter G, Bonvoust F. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001, 34:738-44.
-
(2001)
Hepatology
, vol.34
, pp. 738-744
-
-
Paradis, V.1
Perlemuter, G.2
Bonvoust, F.3
-
72
-
-
0033950690
-
Evaluation of factors controlling glucose tolerance in patients with HCV infection before and after 4 months therapy with interferon-alpha
-
Konrad T, Zeuzem S, Vicini P. Evaluation of factors controlling glucose tolerance in patients with HCV infection before and after 4 months therapy with interferon-alpha. Eur J Clin Invest 2000, 30:111-21.
-
(2000)
Eur J Clin Invest
, vol.30
, pp. 111-121
-
-
Konrad, T.1
Zeuzem, S.2
Vicini, P.3
-
73
-
-
0031448152
-
Changes in glucose tolerance after interferon-alpha therapy in patients with chronic hepatitis C
-
Tanaka H, Shiota G, Kawasaki H. Changes in glucose tolerance after interferon-alpha therapy in patients with chronic hepatitis C. J Med 1997, 28:335-46.
-
(1997)
J Med
, vol.28
, pp. 335-346
-
-
Tanaka, H.1
Shiota, G.2
Kawasaki, H.3
-
74
-
-
15744381704
-
Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
-
Romero-Gomez M, Del Mar Viloria M, Andrade RJ. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005, 128:636-41.
-
(2005)
Gastroenterology
, vol.128
, pp. 636-641
-
-
Romero-Gomez, M.1
Del Mar Viloria, M.2
Andrade, R.J.3
-
75
-
-
0031800754
-
Liver biopsy is a useful predictor of response to interferon therapy in chronic hepatitis C
-
Kaserer K, Fiedler R, Steindl P, Muller CH, Wrba F, Ferenci P. Liver biopsy is a useful predictor of response to interferon therapy in chronic hepatitis C. Histopathology 1998, 32:454-61.
-
(1998)
Histopathology
, vol.32
, pp. 454-461
-
-
Kaserer, K.1
Fiedler, R.2
Steindl, P.3
Muller, C.H.4
Wrba, F.5
Ferenci, P.6
-
76
-
-
17944392178
-
Effect of combined interferon-alpha induction therapy and ribavirin on chronic hepatitis C virus infection: a randomized multicentre study
-
Bjoro K, Bell H, Hellum KB. Effect of combined interferon-alpha induction therapy and ribavirin on chronic hepatitis C virus infection: a randomized multicentre study. Scand J Gastroenterol 2002, 37:226-32.
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 226-232
-
-
Bjoro, K.1
Bell, H.2
Hellum, K.B.3
-
77
-
-
0036892371
-
Efficacy of interferon monotherapy to 394 consecutive naive cases infected with hepatitis C virus genotype 2a in Japan: therapy efficacy as consequence of tripartite interaction of viral, host and interferon treatment-related factors
-
Akuta N, Suzuki F, Tsubota A. Efficacy of interferon monotherapy to 394 consecutive naive cases infected with hepatitis C virus genotype 2a in Japan: therapy efficacy as consequence of tripartite interaction of viral, host and interferon treatment-related factors. J Hepatol 2002, 37:831-6.
-
(2002)
J Hepatol
, vol.37
, pp. 831-836
-
-
Akuta, N.1
Suzuki, F.2
Tsubota, A.3
-
78
-
-
33749589381
-
Impact of liver steatosis on the antiviral response in the hepatitis C virus-associated chronic hepatitis
-
Soresi M, Tripi S, Franco V. Impact of liver steatosis on the antiviral response in the hepatitis C virus-associated chronic hepatitis. Liver Int 2006, 26:1119-25.
-
(2006)
Liver Int
, vol.26
, pp. 1119-1125
-
-
Soresi, M.1
Tripi, S.2
Franco, V.3
-
79
-
-
0043037223
-
High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
-
Bressler BL, Guindi M, Tomlinson G, Heathcote J. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003, 38:639-44.
-
(2003)
Hepatology
, vol.38
, pp. 639-644
-
-
Bressler, B.L.1
Guindi, M.2
Tomlinson, G.3
Heathcote, J.4
-
80
-
-
36349022057
-
Impact of weight-based ribavirin with peginterferon alfa-2b in African Americans with hepatitis C virus genotype 1
-
Jacobson IM, Brown RS, McCone J. Impact of weight-based ribavirin with peginterferon alfa-2b in African Americans with hepatitis C virus genotype 1. Hepatology 2007, 46:982-90.
-
(2007)
Hepatology
, vol.46
, pp. 982-990
-
-
Jacobson, I.M.1
Brown, R.S.2
McCone, J.3
-
81
-
-
0037406263
-
The p38 mitogen-activated protein kinase pathway and its role in interferon signaling
-
Platanias LC. The p38 mitogen-activated protein kinase pathway and its role in interferon signaling. Pharmacol Ther 2003, 98:129-42.
-
(2003)
Pharmacol Ther
, vol.98
, pp. 129-142
-
-
Platanias, L.C.1
-
82
-
-
0034857085
-
Steatosis in chronic hepatitis C: can weight reduction improve therapeutic efficacy?
-
Giannini E, Ceppa P, Testa R. Steatosis in chronic hepatitis C: can weight reduction improve therapeutic efficacy? J Hepatol 2001, 35:432-3.
-
(2001)
J Hepatol
, vol.35
, pp. 432-433
-
-
Giannini, E.1
Ceppa, P.2
Testa, R.3
-
83
-
-
60049094719
-
Pioglitazone improves early virologic kinetic response to PEG IFN/RBV combination therapy in hepatitis C genotype 1 naive pts
-
Elgouhari HCK, Lopez R, Zein NM. Pioglitazone improves early virologic kinetic response to PEG IFN/RBV combination therapy in hepatitis C genotype 1 naive pts. Hepatology 2008, 48(4):383A. Suppl
-
(2008)
Hepatology
, vol.48
, Issue.4 SUPPL
-
-
Elgouhari, H.C.K.1
Lopez, R.2
Zein, N.M.3
-
84
-
-
60049101298
-
A randomized, double blind, placebo-controlled study of PPAR-gamma agonist pioglitazone given in combination with peginterferon and ribavirin in patients with genotype-1 chronic hepatitis C.
-
Conjeevaram HBC, McKenna B, Harsh D. A randomized, double blind, placebo-controlled study of PPAR-gamma agonist pioglitazone given in combination with peginterferon and ribavirin in patients with genotype-1 chronic hepatitis C. Hepatology 2008, 48(4):384A. Suppl
-
(2008)
Hepatology
, vol.48
, Issue.4 SUPPL
-
-
Conjeevaram, H.B.C.1
McKenna, B.2
Harsh, D.3
-
85
-
-
33645114359
-
Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1
-
Walsh MJ, Jonsson JR, Richardson MM. Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1. Gut 2006, 55:529-35.
-
(2006)
Gut
, vol.55
, pp. 529-535
-
-
Walsh, M.J.1
Jonsson, J.R.2
Richardson, M.M.3
-
86
-
-
36349030379
-
Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy
-
Persico M, Capasso M, Persico E. Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy. Hepatology 2007, 46:1009-15.
-
(2007)
Hepatology
, vol.46
, pp. 1009-1015
-
-
Persico, M.1
Capasso, M.2
Persico, E.3
-
87
-
-
72549104493
-
Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin
-
Romero-Gomez M, Diago M, Andrade RJ. Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin. Hepatology 2009, 50:1702-8.
-
(2009)
Hepatology
, vol.50
, pp. 1702-1708
-
-
Romero-Gomez, M.1
Diago, M.2
Andrade, R.J.3
-
88
-
-
0036158719
-
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
-
Lerat H, Honda M, Beard MR. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology 2002, 122:352-65.
-
(2002)
Gastroenterology
, vol.122
, pp. 352-365
-
-
Lerat, H.1
Honda, M.2
Beard, M.R.3
-
89
-
-
0037714524
-
Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection
-
Ohata K, Hamasaki K, Toriyama K. Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection. Cancer 2003, 97:3036-43.
-
(2003)
Cancer
, vol.97
, pp. 3036-3043
-
-
Ohata, K.1
Hamasaki, K.2
Toriyama, K.3
-
90
-
-
33846850496
-
Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis
-
Moriishi K, Mochizuki R, Moriya K. Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis. Proc Natl Acad Sci USA 2007, 104:1661-6.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1661-1666
-
-
Moriishi, K.1
Mochizuki, R.2
Moriya, K.3
-
91
-
-
33846849610
-
Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein
-
Miyamoto H, Moriishi K, Moriya K. Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein. J Virol 2007, 81:1727-35.
-
(2007)
J Virol
, vol.81
, pp. 1727-1735
-
-
Miyamoto, H.1
Moriishi, K.2
Moriya, K.3
-
92
-
-
33644660193
-
Hepatic steatosis and the risk of hepatocellular carcinoma in chronic hepatitis C
-
Kumar D, Farrell GC, Kench J, George J. Hepatic steatosis and the risk of hepatocellular carcinoma in chronic hepatitis C. J Gastroenterol Hepatol 2005, 20:1395-400.
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 1395-1400
-
-
Kumar, D.1
Farrell, G.C.2
Kench, J.3
George, J.4
-
93
-
-
34250339305
-
Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis
-
Pekow JR, Bhan AK, Zheng H, Chung RT. Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis. Cancer 2007, 109:2490-6.
-
(2007)
Cancer
, vol.109
, pp. 2490-2496
-
-
Pekow, J.R.1
Bhan, A.K.2
Zheng, H.3
Chung, R.T.4
|