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Volumn 40, Issue 5, 2010, Pages 486-493

Portal vein thrombosis in Egyptian patients with liver cirrhosis: Role of methylenetetrahydrofolate reductase C677T gene mutation

Author keywords

Genetics; Homocysteine; Liver cirrhosis; Methylenetetrahydrofolate reductase; Portal vein thrombosis

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALBUMIN; ANTITHROMBIN III; BILIRUBIN; HOMOCYSTEINE; PROTEIN C; PROTEIN S; PROTHROMBIN;

EID: 77954378609     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2010.00628.x     Document Type: Article
Times cited : (23)

References (46)
  • 1
    • 0021860987 scopus 로고
    • Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients
    • Okuda K, Ohnishi K, Kimura K. Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients. Gastroenterology 1985, 89:279-86.
    • (1985) Gastroenterology , vol.89 , pp. 279-286
    • Okuda, K.1    Ohnishi, K.2    Kimura, K.3
  • 2
    • 49649087497 scopus 로고    scopus 로고
    • Portal vein thrombosis in liver cirrhosis
    • Fimognari FL, Violi F. Portal vein thrombosis in liver cirrhosis. Intern Emerg Med 2008, 3:213-18.
    • (2008) Intern Emerg Med , vol.3 , pp. 213-218
    • Fimognari, F.L.1    Violi, F.2
  • 3
    • 0034780255 scopus 로고    scopus 로고
    • Extrahepatic portal vein thrombosis: aetiology and determinants of survival
    • Janssen HL, Wijnhoud A, Haagsma EB. Extrahepatic portal vein thrombosis: aetiology and determinants of survival. Gut 2001, 49:720-4.
    • (2001) Gut , vol.49 , pp. 720-724
    • Janssen, H.L.1    Wijnhoud, A.2    Haagsma, E.B.3
  • 4
    • 0034098696 scopus 로고    scopus 로고
    • Portal vein thrombosis in adults: pathophysiology, pathogenesis and management
    • Valla DC, Condat B. Portal vein thrombosis in adults: pathophysiology, pathogenesis and management. J Hepatol 2000, 32:865-71.
    • (2000) J Hepatol , vol.32 , pp. 865-871
    • Valla, D.C.1    Condat, B.2
  • 6
    • 0036126279 scopus 로고    scopus 로고
    • Portal vein thrombosis: a concise review
    • Sobhonslidsuk A, Reddy KR. Portal vein thrombosis: a concise review. Am J Gastroenterol 2002, 97:535-41.
    • (2002) Am J Gastroenterol , vol.97 , pp. 535-541
    • Sobhonslidsuk, A.1    Reddy, K.R.2
  • 7
    • 12944316466 scopus 로고    scopus 로고
    • Review article: portal vein thrombosis - new insights into aetiology and management
    • Webster GJ, Burroughs AK, Riordan SM. Review article: portal vein thrombosis - new insights into aetiology and management. Aliment Pharmacol Ther 2005, 21:1-9.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 1-9
    • Webster, G.J.1    Burroughs, A.K.2    Riordan, S.M.3
  • 8
    • 38649088635 scopus 로고    scopus 로고
    • Coagulation abnormalities in cirrhotic patients with portal vein thrombosis
    • Amitrano L, Guardascione MA, Ames PR. Coagulation abnormalities in cirrhotic patients with portal vein thrombosis. Clin Lab 2007, 53:583-9.
    • (2007) Clin Lab , vol.53 , pp. 583-589
    • Amitrano, L.1    Guardascione, M.A.2    Ames, P.R.3
  • 9
    • 0035120187 scopus 로고    scopus 로고
    • G20210A prothrombin gene mutation and other thrombophilic polymorphisms in patients with portal or hepatic venous thrombosis
    • Madonna P, De Stefano V, Coppola A, Cerbone AM, Di Minno G. G20210A prothrombin gene mutation and other thrombophilic polymorphisms in patients with portal or hepatic venous thrombosis. Gastroenterology 2001, 120:1059-67.
    • (2001) Gastroenterology , vol.120 , pp. 1059-1067
    • Madonna, P.1    De Stefano, V.2    Coppola, A.3    Cerbone, A.M.4    Di Minno, G.5
  • 10
    • 21244470295 scopus 로고    scopus 로고
    • Portal vein thrombosis: what is the role of genetics
    • Walker AP. Portal vein thrombosis: what is the role of genetics. Eur J Gastroenterol Hepatol 2005, 17:705-7.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 705-707
    • Walker, A.P.1
  • 11
    • 0030946890 scopus 로고    scopus 로고
    • Clinical chemistry and molecular biology of homocysteine metabolism: an update
    • Miner SE, Evrovski J, Cole DE. Clinical chemistry and molecular biology of homocysteine metabolism: an update. Clin Biochem 1997, 30:189-201.
    • (1997) Clin Biochem , vol.30 , pp. 189-201
    • Miner, S.E.1    Evrovski, J.2    Cole, D.E.3
  • 13
    • 1642586763 scopus 로고    scopus 로고
    • Molecular biology of 5,10-methylenetetrahydrofolate reductase
    • Fodinger M, Horl WH, Sunder-Plassmann G. Molecular biology of 5,10-methylenetetrahydrofolate reductase. J Nephrol 2000, 13:20-33.
    • (2000) J Nephrol , vol.13 , pp. 20-33
    • Fodinger, M.1    Horl, W.H.2    Sunder-Plassmann, G.3
  • 14
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995, 10:111-13.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 16
    • 0034994203 scopus 로고    scopus 로고
    • MTHFR gene polymorphism, homocysteine and cardiovascular disease
    • Cortese C, Motti C. MTHFR gene polymorphism, homocysteine and cardiovascular disease. Public Health Nutr 2001, 4:493-7.
    • (2001) Public Health Nutr , vol.4 , pp. 493-497
    • Cortese, C.1    Motti, C.2
  • 17
    • 0035065689 scopus 로고    scopus 로고
    • Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis
    • Lim PS, Hung WR, Wei YH. Polymorphism in methylenetetrahydrofolate reductase gene: its impact on plasma homocysteine levels and carotid atherosclerosis in ESRD patients receiving hemodialysis. Nephron 2001, 87:249-56.
    • (2001) Nephron , vol.87 , pp. 249-256
    • Lim, P.S.1    Hung, W.R.2    Wei, Y.H.3
  • 18
    • 0030728742 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase gene polymorphism with carotid arterial wall thickening and myocardial infarction risk in NIDDM
    • Arai K, Yamasaki Y, Kajimoto Y. Association of methylenetetrahydrofolate reductase gene polymorphism with carotid arterial wall thickening and myocardial infarction risk in NIDDM. Diabetes 1997, 46:2102-4.
    • (1997) Diabetes , vol.46 , pp. 2102-2104
    • Arai, K.1    Yamasaki, Y.2    Kajimoto, Y.3
  • 20
    • 0029893568 scopus 로고    scopus 로고
    • Validated questionnaire for the identification of previous personal or familial venous thromboembolism
    • Frezzato M, Tosetto A, Rodeghiero F. Validated questionnaire for the identification of previous personal or familial venous thromboembolism. Am J Epidemiol 1996, 143:1257-65.
    • (1996) Am J Epidemiol , vol.143 , pp. 1257-1265
    • Frezzato, M.1    Tosetto, A.2    Rodeghiero, F.3
  • 22
    • 0028000832 scopus 로고
    • Use of confirmatory assays for diagnosis of hepatitis C viral infection in patients with hepatocellular carcinoma
    • Mangia A, Vallari D, Di Bisceglie AM. Use of confirmatory assays for diagnosis of hepatitis C viral infection in patients with hepatocellular carcinoma. J Med Virol 1994, 43:125-8.
    • (1994) J Med Virol , vol.43 , pp. 125-128
    • Mangia, A.1    Vallari, D.2    Di Bisceglie, A.M.3
  • 23
    • 0031886747 scopus 로고    scopus 로고
    • An enzyme conversion immunoassay for determining total homocysteine in plasma or serum
    • Frantzen F, Faaren AL, Alfheim I, Nordhei AK. An enzyme conversion immunoassay for determining total homocysteine in plasma or serum. Clin Chem 1998, 44:311-16.
    • (1998) Clin Chem , vol.44 , pp. 311-316
    • Frantzen, F.1    Faaren, A.L.2    Alfheim, I.3    Nordhei, A.K.4
  • 24
    • 0027469085 scopus 로고
    • Ischemic stroke due to deficiency of coagulation inhibitors. Report of 10 young adults
    • Martinez HR, Rangel-Guerra RA, Marfil LJ. Ischemic stroke due to deficiency of coagulation inhibitors. Report of 10 young adults. Stroke 1993, 24:19-25.
    • (1993) Stroke , vol.24 , pp. 19-25
    • Martinez, H.R.1    Rangel-Guerra, R.A.2    Marfil, L.J.3
  • 25
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques PF, Bostom AG, Williams RR. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996, 93:7-9.
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3
  • 26
    • 33646441796 scopus 로고    scopus 로고
    • Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23796 consecutive autopsies
    • Ögren M, Bergqvist D, Björck M, Acosta S, Eriksson H, Sternby NH. Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23796 consecutive autopsies. World J Gastroenterol 2006, 12:2115-19.
    • (2006) World J Gastroenterol , vol.12 , pp. 2115-2119
    • Ögren, M.1    Bergqvist, D.2    Björck, M.3    Acosta, S.4    Eriksson, H.5    Sternby, N.H.6
  • 27
    • 0037633079 scopus 로고    scopus 로고
    • Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies
    • Ray JG, Shmorgun D, Chan WS. Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies. Pathophysiol Haemost Thromb 2002, 32:51-8.
    • (2002) Pathophysiol Haemost Thromb , vol.32 , pp. 51-58
    • Ray, J.G.1    Shmorgun, D.2    Chan, W.S.3
  • 28
    • 0034827690 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as a risk factor for venous thrombosis
    • den Heijer M, Keijzer MB. Hyperhomocysteinemia as a risk factor for venous thrombosis. Clin Chem Lab Med 2001, 39:710-13.
    • (2001) Clin Chem Lab Med , vol.39 , pp. 710-713
    • den Heijer, M.1    Keijzer, M.B.2
  • 29
    • 0032569645 scopus 로고    scopus 로고
    • Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
    • Ray JG. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med 1998, 158:2101-6.
    • (1998) Arch Intern Med , vol.158 , pp. 2101-2106
    • Ray, J.G.1
  • 30
    • 18344398980 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation
    • Margaglione M, D'Andrea G, d'Addedda M. The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation. Thromb Haemost 1998, 79:907-11.
    • (1998) Thromb Haemost , vol.79 , pp. 907-911
    • Margaglione, M.1    D'Andrea, G.2    d'Addedda, M.3
  • 31
    • 34250333053 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and thrombosis: an overview
    • Eldibany MM, Caprini JA. Hyperhomocysteinemia and thrombosis: an overview. Arch Pathol Lab Med 2007, 131:872-84.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 872-884
    • Eldibany, M.M.1    Caprini, J.A.2
  • 32
    • 14044276314 scopus 로고    scopus 로고
    • Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function
    • Weiss N. Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function. Curr Drug Metab 2005, 6:27-36.
    • (2005) Curr Drug Metab , vol.6 , pp. 27-36
    • Weiss, N.1
  • 33
    • 33646002652 scopus 로고    scopus 로고
    • MTHFR C677T mutations in liver cirrhosis with and without portal vein thrombosis
    • Pasta L, Marrone C, D'Amico M. MTHFR C677T mutations in liver cirrhosis with and without portal vein thrombosis. Liver Int 2006, 26:269-70.
    • (2006) Liver Int , vol.26 , pp. 269-270
    • Pasta, L.1    Marrone, C.2    D'Amico, M.3
  • 34
    • 0033967582 scopus 로고    scopus 로고
    • Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis
    • Amitrano L, Brancaccio V, Guardascione MA. Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis. Hepatology 2000, 31:345-8.
    • (2000) Hepatology , vol.31 , pp. 345-348
    • Amitrano, L.1    Brancaccio, V.2    Guardascione, M.A.3
  • 35
    • 54049156457 scopus 로고    scopus 로고
    • Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype
    • Hotoleanu C, Andercou O, Andercou A. Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype. Vasc Endovasc Surg 2008, 42:477-81.
    • (2008) Vasc Endovasc Surg , vol.42 , pp. 477-481
    • Hotoleanu, C.1    Andercou, O.2    Andercou, A.3
  • 36
    • 11044231850 scopus 로고    scopus 로고
    • Heterozygous prothrombin 20210G/A mutation, associated with hyperhomocysteinemia, and homozygous methylenetetrahydrofolate reductase 677 C/T mutation, in a patient with portal and mesenteric venous thrombosis
    • Elhajj II, Salem ZM, Birjawi GA, Taher AT, Soweid AM. Heterozygous prothrombin 20210G/A mutation, associated with hyperhomocysteinemia, and homozygous methylenetetrahydrofolate reductase 677 C/T mutation, in a patient with portal and mesenteric venous thrombosis. Hematol J 2004, 5:540-2.
    • (2004) Hematol J , vol.5 , pp. 540-542
    • Elhajj, I.I.1    Salem, Z.M.2    Birjawi, G.A.3    Taher, A.T.4    Soweid, A.M.5
  • 37
    • 0036636740 scopus 로고    scopus 로고
    • Portal vein thrombosis in a patient with hyperhomocysteinemia
    • Svehlová M, Stepánková L, Kaupeová P, Sykora J. Portal vein thrombosis in a patient with hyperhomocysteinemia. Vnitr Lek 2002, 48:671-4.
    • (2002) Vnitr Lek , vol.48 , pp. 671-674
    • Svehlová, M.1    Stepánková, L.2    Kaupeová, P.3    Sykora, J.4
  • 38
    • 0036294983 scopus 로고    scopus 로고
    • Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia
    • Amitrano L, Brancaccio V, Guardascione MA. Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia. Endoscopy 2002, 34:535-8.
    • (2002) Endoscopy , vol.34 , pp. 535-538
    • Amitrano, L.1    Brancaccio, V.2    Guardascione, M.A.3
  • 39
    • 58149133721 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption
    • Fabris C, Toniutto P, Falleti E. MTHFR C677T polymorphism and risk of HCC in patients with liver cirrhosis: role of male gender and alcohol consumption. Alcohol Clin Exp Res 2009, 33:102-7.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 102-107
    • Fabris, C.1    Toniutto, P.2    Falleti, E.3
  • 40
    • 77954362087 scopus 로고    scopus 로고
    • The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR) and consecutive hyperhomocysteinemia are responsible for vascular complications after liver transplantation
    • Suppl
    • Akoglu B, Kindl P, Weber N, Trojan J, Caspary WF, Faust D. The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR) and consecutive hyperhomocysteinemia are responsible for vascular complications after liver transplantation. Hepatology 2005, 42(1):329A. Suppl
    • (2005) Hepatology , vol.42 , Issue.1
    • Akoglu, B.1    Kindl, P.2    Weber, N.3    Trojan, J.4    Caspary, W.F.5    Faust, D.6
  • 41
    • 21244479368 scopus 로고    scopus 로고
    • Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors
    • Mangia A, Villani MR, Cappucci G. Causes of portal venous thrombosis in cirrhotic patients: the role of genetic and acquired factors. Eur J Gastroenterol Hepatol 2005, 17:745-51.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 745-751
    • Mangia, A.1    Villani, M.R.2    Cappucci, G.3
  • 42
    • 20144374543 scopus 로고    scopus 로고
    • Thrombophilic gene mutations in cirrhotic patients with portal vein thrombosis
    • Erkan O, Bozdayi AM, Disibeyaz S. Thrombophilic gene mutations in cirrhotic patients with portal vein thrombosis. Eur J Gastroenterol Hepatol 2005, 17:339-43.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 339-343
    • Erkan, O.1    Bozdayi, A.M.2    Disibeyaz, S.3
  • 43
    • 1942471058 scopus 로고    scopus 로고
    • Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis
    • Amitrano L, Guardascione MA, Brancaccio V. Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis. J Hepatol 2004, 40:736-41.
    • (2004) J Hepatol , vol.40 , pp. 736-741
    • Amitrano, L.1    Guardascione, M.A.2    Brancaccio, V.3
  • 44
    • 33748416345 scopus 로고    scopus 로고
    • Portal vein thrombosis secondary to hyperhomocysteinemia: a case report
    • Tan KJ, Chow PK, Tan YM, Thng CH. Portal vein thrombosis secondary to hyperhomocysteinemia: a case report. Dig Dis Sci 2006, 51:1218-20.
    • (2006) Dig Dis Sci , vol.51 , pp. 1218-1220
    • Tan, K.J.1    Chow, P.K.2    Tan, Y.M.3    Thng, C.H.4
  • 45
    • 33746490003 scopus 로고    scopus 로고
    • Hyperhomocysteinemia complicated by myocardial infarction and portal vein thrombosis-case report
    • Dworakowska D, Kazimierska E, Weyer-Hepka J. Hyperhomocysteinemia complicated by myocardial infarction and portal vein thrombosis-case report. Pol Arch Med Wewn 2006, 115:234-7.
    • (2006) Pol Arch Med Wewn , vol.115 , pp. 234-237
    • Dworakowska, D.1    Kazimierska, E.2    Weyer-Hepka, J.3


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