메뉴 건너뛰기




Volumn 24, Issue 3, 2010, Pages 165-173

Free radical-scavenging activity and DNA damaging potential of auxins IAA and 2-methyl-IAA evaluated in human neutrophils by the alkaline comet assay

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 METHYL INDOLE 3 ACETIC ACID; AUXIN; INDOLEACETIC ACID; PEROXIDASE; UNCLASSIFIED DRUG; 2-METHYL-INDOLE-3-ACETIC ACID; INDOLEACETIC ACID DERIVATIVE; SCAVENGER;

EID: 77954372057     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20323     Document Type: Article
Times cited : (11)

References (51)
  • 1
    • 0032189889 scopus 로고    scopus 로고
    • Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil
    • DOI 10.1016/S0306-3623(98)00032-9, PII S0306362398000329
    • De Melo MP, Curi TCP, Miyasaka CK, Palanch AC, Curi R. Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil. Gen Pharmacol 1998;141:573-578. (Pubitemid 28458926)
    • (1998) General Pharmacology , vol.31 , Issue.4 , pp. 573-578
    • De Melo, M.P.1    Curi, T.C.P.2    Miyasaka, C.K.3    Palanch, A.C.4    Curi, R.5
  • 3
    • 0037119677 scopus 로고    scopus 로고
    • Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential of targeted cancer therapy
    • Rossiter S, Folkes LK, Wardman P. Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential of targeted cancer therapy. Bioorg Med Chem Lett 2002;12:2523-2526.
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 2523-2526
    • Rossiter, S.1    Folkes, L.K.2    Wardman, P.3
  • 4
    • 33746710405 scopus 로고    scopus 로고
    • Indole-3-acetic acid/horseradish peroxidase-induced apoptosis involves cell surface CD95 (Fas/APO-1) expression
    • Kim D-S, Kim S-Y, Jeong Y-M, Jeon S-E, Kim M-K, Kwon S-B, Park K-C. Indole-3-acetic acid/horseradish peroxidase-induced apoptosis involves cell surface CD95 (Fas/APO-1) expression. Biol Pharm Bull 2006;29:1625-1629.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1625-1629
    • Kim, D.-S.1    Kim, S.-Y.2    Jeong, Y.-M.3    Jeon, S.-E.4    Kim, M.-K.5    Kwon, S.-B.6    Park, K.-C.7
  • 5
    • 0033212372 scopus 로고    scopus 로고
    • Apoptosis induction in nonirradiated human HL-60 and murine NSO/2 tumor cells by photoproducts of indole-3-acetic acid and riboflavin
    • Edwards AM, Barredo F, Silva E, De Joannes AE, Becker MI. Apoptosis induction in nonirradiated human HL-60 and murine NSO/2 tumor cells by photoproducts of indole-3-acetic acid and riboflavin. Photochem Photobiol 1999;70:645-649. (Pubitemid 129555836)
    • (1999) Photochemistry and Photobiology , vol.70 , Issue.4 , pp. 645-649
    • Edwards, A.M.1    Barredo, F.2    Silva, E.3    De Ioannes, A.E.4    Becker, M.I.5
  • 6
    • 0037442684 scopus 로고    scopus 로고
    • Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid)
    • Folkes LK, Wardman P. Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid). Cancer Res 2003;63:776-779. (Pubitemid 36231975)
    • (2003) Cancer Research , vol.63 , Issue.4 , pp. 776-779
    • Folkes, L.K.1    Wardman, P.2
  • 7
    • 0242321121 scopus 로고    scopus 로고
    • Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells
    • Kim D-S, Jeon S-E, Park K-C. Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells. Cell Signal 2004;16:81-88.
    • (2004) Cell Signal , vol.16 , pp. 81-88
    • Kim, D.-S.1    Jeon, S.-E.2    Park, K.-C.3
  • 9
    • 32344443328 scopus 로고    scopus 로고
    • Hydrogen peroxide is a mediator of indole-3-acetic acid/horseradish peroxidase-induced apoptosis
    • DOI 10.1016/j.febslet.2006.01.073, PII S0014579306001438
    • Kim D-S, Jeon S-E, Jeong Y-M, Kim S-Y, Kwon S-B, Park K-C. Hydrogen peroxide is a mediator of indole-3-acetic acid/horseradish peroxidase-induced apoptosis. FEBS Lett 2006;580:1439-1446. (Pubitemid 43222012)
    • (2006) FEBS Letters , vol.580 , Issue.5 , pp. 1439-1446
    • Kim, D.-S.1    Jeon, S.-E.2    Jeong, Y.-M.3    Kim, S.-Y.4    Kwon, S.-B.5    Park, K.-C.6
  • 10
    • 2442570889 scopus 로고    scopus 로고
    • Reactions of indole derivatives with cardioprotective activity with reactive oxygen species. Comparison with melatonin
    • Andreadou I, Tsantili-Kakoulidou A, Spyropoulou E, Siatra T. Reactions of indole derivatives with cardioprotective activity with reactive oxygen species. Comparison with melatonin. Chem Pharm Bull 2003;51:1128-1131.
    • (2003) Chem Pharm Bull , vol.51 , pp. 1128-1131
    • Andreadou, I.1    Tsantili-Kakoulidou, A.2    Spyropoulou, E.3    Siatra, T.4
  • 11
    • 28944443424 scopus 로고    scopus 로고
    • Effect of indole acetic acid administration on the neutrophil functions and oxidative stress from neutrophil, mesenteric lymph node and liver
    • Lins PG, Valle CR, Pugine SMP, Oliveira DL, Ferreira MSL, Costa EJX, Pires de Melo M. Effect of indole acetic acid administration on the neutrophil functions and oxidative stress from neutrophil, mesenteric lymph node and liver. Life Sci 2006;78:564-570.
    • (2006) Life Sci , vol.78 , pp. 564-570
    • Lins, P.G.1    Valle, C.R.2    Pugine, S.M.P.3    Oliveira, D.L.4    Ferreira, M.S.L.5    Costa, E.J.X.6    Pires De Melo, M.7
  • 13
    • 85069238953 scopus 로고    scopus 로고
    • Available at
    • The University of Texas M. D. Anderson Cancer Center. Available at: http://www.mdanderson.org/Featured Sites/flowcytometry/display.cfm?id=74824C6D- 381F-4317-A7D345F1CD728E53&method=displayFull#sample prep.
  • 14
    • 33746696062 scopus 로고    scopus 로고
    • Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs
    • Costa D, Moutinho L, Lima JLFC, Fernandes E. Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs. Biol Pharm Bull 2006;29:1659-1670.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1659-1670
    • Costa, D.1    Moutinho, L.2    Lima, J.L.F.C.3    Fernandes, E.4
  • 15
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh NP, Mc Coy MT, Tice RR, Schneider EL. A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-191.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    Mc Coy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 16
    • 34250654965 scopus 로고    scopus 로고
    • The comet assay: Amethod tomeasure DNA damage in individual cells
    • Olive P, Banáth JP. The comet assay: amethod tomeasure DNA damage in individual cells. Nat Protoc 2006;1:23-29.
    • (2006) Nat Protoc , vol.1 , pp. 23-29
    • Olive, P.1    Banáth, J.P.2
  • 17
    • 0037756724 scopus 로고    scopus 로고
    • Measurement of DNA breaks and oxidative damage in polymorphonuclear and mononuclear white blood cells: A novel approach using the comet assay
    • Giovannelli L, Pitozzi V, Riolo S, Dolara P. Measurement of DNA breaks and oxidative damage in polymorphonuclear and mononuclear white blood cells: a novel approach using the comet assay. Mutat Res 2003;538:71-80.
    • (2003) Mutat Res , vol.538 , pp. 71-80
    • Giovannelli, L.1    Pitozzi, V.2    Riolo, S.3    Dolara, P.4
  • 18
    • 0032860529 scopus 로고    scopus 로고
    • DNA damage by tobacco smoke and some antiblastic drugs evaluated using the Comet assay
    • DOI 10.1016/S0378-4274(99)00098-3, PII S0378427499000983
    • Poli P, Buschini A, Spaggiari A, Rizzoli V, Carlo-Stella C, Rossi C. DNA damage by tobacco smoke and some antiblastid drugs evaluated using the comet assay. Toxicol Lett 1999;108:267-276. (Pubitemid 29460794)
    • (1999) Toxicology Letters , vol.108 , Issue.2-3 , pp. 267-276
    • Poli, P.1    Buschini, A.2    Spaggiari, A.3    Rizzoli, V.4    Carlo-Stella, C.5    Rossi, C.6
  • 20
    • 8744272161 scopus 로고    scopus 로고
    • Evaluation of in vitro genotoxic activity of bleomycin and mitomycin C in human lymphocytes using the alkaline comet assay
    • Milić M, Kopjar N. Evaluation of in vitro genotoxic activity of bleomycin andmitomycin C in humanlymphocytes using the alkaline comet assay. Arh Hig Rada Toksikol 2004;55:249-259. (Pubitemid 39524097)
    • (2004) Arhiv Za Higijenu Rada I Toksikologiju , vol.55 , Issue.4 , pp. 249-259
    • Milic, M.1    Kopjar, N.2
  • 21
    • 33845952418 scopus 로고    scopus 로고
    • Radical scavenging ability of polyphenolic compounds towards DPPH free radical
    • DOI 10.1016/j.talanta.2006.03.050, PII S0039914006002499
    • Villaño D, Fernández-Pachón MS, Moyá ML, Troncoso AM, García-Parrilla MC. Radical scavenging ability of polyphenolic compounds towards DPPH free radical. Talanta 2007;71:230-235. (Pubitemid 46038394)
    • (2007) Talanta , vol.71 , Issue.1 , pp. 230-235
    • Villano, D.1    Fernandez-Pachon, M.S.2    Moya, M.L.3    Troncoso, A.M.4    Garcia-Parrilla, M.C.5
  • 22
    • 0033664464 scopus 로고    scopus 로고
    • Development of a novel enzyme/prodrug combination of gene therapy of cancer: Horseradish peroxidase/indole-3-acetic acid
    • Greco O, Folkes LK, Wardman P, Tozer GM, Dachs GU. Development of a novel enzyme/prodrug combination of gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid. Cancer Gene Ther 2000;7:1414-1420.
    • (2000) Cancer Gene Ther , vol.7 , pp. 1414-1420
    • Greco, O.1    Folkes, L.K.2    Wardman, P.3    Tozer, G.M.4    Dachs, G.U.5
  • 24
    • 0036191855 scopus 로고    scopus 로고
    • Oxic and anoxic enhancement of radiation-mediated toxicity by horseradish peroxidase/indole-3-acetic acid gene therapy
    • DOI 10.1080/09553000110097983
    • Greco O, Tozer GM, Dachs GU. Oxic and anoxic enhancement of radiation-mediated toxicity by horseradish/indole-3-acetic acid gene therapy. Int J Radiat Biol 2002;78:173-181. (Pubitemid 34208321)
    • (2002) International Journal of Radiation Biology , vol.78 , Issue.3 , pp. 173-181
    • Greco, O.1    Tozer, G.M.2    Dachs, G.U.3
  • 25
    • 8544283254 scopus 로고    scopus 로고
    • The comet assay for DNA damage and repair
    • Collins AR. The comet assay for DNA damage and repair. Mol Biotechnol 2004;26:249-261.
    • (2004) Mol Biotechnol , vol.26 , pp. 249-261
    • Collins, A.R.1
  • 28
    • 0035909485 scopus 로고    scopus 로고
    • Contribution of apoptosis to responses in the comet assay
    • Roser S, Pool-Zobel B-L, Rechkemmer G. Contribution of apoptosis to responses in the comet assay. Mutat Res 2001;497:169-175.
    • (2001) Mutat Res , vol.497 , pp. 169-175
    • Roser, S.1    Pool-Zobel, B.-L.2    Rechkemmer, G.3
  • 30
    • 0028884765 scopus 로고
    • Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent
    • Olive P, Banáth JP. Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp Cell Res 1995;221:19-26.
    • (1995) Exp Cell Res , vol.221 , pp. 19-26
    • Olive, P.1    Banáth, J.P.2
  • 31
    • 0034694162 scopus 로고    scopus 로고
    • Analysis of chromate-induced DNA-protein crosslinks with the comet assay
    • Merk O, Reiser K, Speit G. Analysis of chromate-induced DNA-protein crosslinks with the comet assay. Mutat Res 2000;471:71-80.
    • (2000) Mutat Res , vol.471 , pp. 71-80
    • Merk, O.1    Reiser, K.2    Speit, G.3
  • 32
    • 0032584399 scopus 로고    scopus 로고
    • Detection of DNA lesions induced by chemical mutagens by the single cell electrophoresis (Comet) assay 1. Relationship between the onset of DNA damage and the characteristics of mutagens
    • Miyamae Y, Zaizen K, Ohara K, Mine Y, Sasaki YF. Detection of DNA lesions induced by chemical mutagens by the single cell electrophoresis (Comet) assay 1. Relationship between the onset of DNA damage and the characteristics of mutagens. Mutat Res 1998;415:229-235.
    • (1998) Mutat Res , vol.415 , pp. 229-235
    • Miyamae, Y.1    Zaizen, K.2    Ohara, K.3    Mine, Y.4    Sasaki, Y.F.5
  • 33
    • 0030798171 scopus 로고    scopus 로고
    • Effect of hepatic methyl donor status on urinary excretion and DNA damage in B6C3F1 mice treated with sodium arsenite
    • Tice RR, Yager JW, Andrews P, Crecelius E. Effect of hepatic methyl donor status on urinary excretion and DNA damage in B6C3F1 mice treated with sodium arsenite. Mutat Res 1997;386:315-334.
    • (1997) Mutat Res , vol.386 , pp. 315-334
    • Tice, R.R.1    Yager, J.W.2    Andrews, P.3    Crecelius, E.4
  • 36
    • 0345204755 scopus 로고    scopus 로고
    • Detection and activity evaluation of radical scavenging compounds by using DPPH free radical and on-line HPLC-DPPH methods
    • Bandonieniė D, Murkovic M, Pfannhauser W, Venskutonis PR, Gruzdienė D. Detection and activity evaluation of radical scavenging compounds by using DPPH free radical and on-line HPLC-DPPH methods. Eur Food Res Technol 2002;214:143-147.
    • (2002) Eur Food Res Technol , vol.214 , pp. 143-147
    • Bandonienie, D.1    Murkovic, M.2    Pfannhauser, W.3    Venskutonis, P.R.4    Gruzdiene, D.5
  • 39
    • 0017152022 scopus 로고
    • Studies on the mechanism of metabolic stimulation in polymorphonuclear leukocytes during phagocytosis. Activators and inhibitors of the granule bound NADPH oxidase
    • Patriarca P, Dri P, Kakinuma K, Rossi F. Studies on the mechanism of metabolic stimulation in polymorphonuclear leukocytes during phagocytosis. Activators and inhibitors of the granule bound NADPH oxidase.Mol Cell Biochem 1976;12:137-146.
    • (1976) Mol Cell Biochem , vol.12 , pp. 137-146
    • Patriarca, P.1    Dri, P.2    Kakinuma, K.3    Rossi, F.4
  • 40
    • 0032741371 scopus 로고    scopus 로고
    • NADPH oxidase activation and assembly during phagocytosis
    • DeLeo FR, Allen L-AH, Apicella M, Nauseef WM. NADPH oxidase activation and assembly during phagocytosis. J Immunol 1999;163:6732-6740.
    • (1999) J Immunol , vol.163 , pp. 6732-6740
    • DeLeo, F.R.1    Allen, L.-A.H.2    Apicella, M.3    Nauseef, W.M.4
  • 41
    • 0035793541 scopus 로고    scopus 로고
    • Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components
    • Palicz A, Foubert TR, Jesaitis AJ, Marodi L, McPhail LC. Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components. J Biol Chem 2001;276:3090-3097.
    • (2001) J Biol Chem , vol.276 , pp. 3090-3097
    • Palicz, A.1    Foubert, T.R.2    Jesaitis, A.J.3    Marodi, L.4    McPhail, L.C.5
  • 44
    • 77954367246 scopus 로고    scopus 로고
    • The sources and the targets of oxidative stress in the etiology of diabetic complications
    • Mohora M, Greabu M, Muscurel C, Duta C, Totan A. The sources and the targets of oxidative stress in the etiology of diabetic complications. Romanian J Biophys 2007;17:63-84.
    • (2007) Romanian J Biophys , vol.17 , pp. 63-84
    • Mohora, M.1    Greabu, M.2    Muscurel, C.3    Duta, C.4    Totan, A.5
  • 46
    • 36949063535 scopus 로고
    • Antioxidant determinations by the use of a stable free radical
    • Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 1958;181:1199-1200.
    • (1958) Nature , vol.181 , pp. 1199-1200
    • Blois, M.S.1
  • 48
    • 0023879185 scopus 로고
    • Ultrastructural quantitation of peroxidase-and elastase-containing granules in human neutrophils
    • Damiano VV, Kucich U, Murer E, Laudenslager N, Weinbaum G. Ultrastructural quantitation of peroxidase-and elastase-containing granules in human neutrophils. Am J Pathol 1988;131:235-245.
    • (1988) Am J Pathol , vol.131 , pp. 235-245
    • Damiano, V.V.1    Kucich, U.2    Murer, E.3    Laudenslager, N.4    Weinbaum, G.5
  • 49
    • 33747099229 scopus 로고    scopus 로고
    • Measurement of peroxidase activity in single neutrophils by combining catalyzedenzyme reaction and epi-fluorescence microscopy
    • Wenpeng L, Wenrui J. Measurement of peroxidase activity in single neutrophils by combining catalyzedenzyme reaction and epi-fluorescence microscopy. Talanta 2006;70:251-256.
    • (2006) Talanta , vol.70 , pp. 251-256
    • Wenpeng, L.1    Wenrui, J.2
  • 50
    • 0032926333 scopus 로고    scopus 로고
    • Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro
    • Folkes LK, Dennis MF, Stratford MRL, Candeias LP, Wardman P. Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro. Biochem Pharmacol 1999;57:375-382.
    • (1999) Biochem Pharmacol , vol.57 , pp. 375-382
    • Folkes, L.K.1    Dennis, M.F.2    Stratford, M.R.L.3    Candeias, L.P.4    Wardman, P.5
  • 51
    • 0035863281 scopus 로고    scopus 로고
    • Oxidative activation of indole-3-acetic acids to cytotoxic species - A potential new role for plant auxins in cancer therapy
    • Folkes LK, Wardman P. Oxidative activation of indole-3-acetic acids to cytotoxic species - a potential new role for plant auxins in cancer therapy. Biochem Pharmacol 2001;61:129-136.
    • (2001) Biochem Pharmacol , vol.61 , pp. 129-136
    • Folkes, L.K.1    Wardman, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.