Radical mechanisms in nitrosamine-and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells

Toxicological Sciences

Volumn 116, Issue 1, 2010, Pages 194-205

  Hebels, Dennie G A J ^a   Briedé, Jacob J ^a   Khampang, Roongnapa ^a   Kleinjans, Jos C S ^a   de Kok, Theo M C M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Colon carcinogenesis; Free radicals; N nitroso compounds; Nitrosamides; Nitrosamines; Toxicogenomics

Indexed keywords

1 NITROSOPIPERIDINE; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; DNA; FREE RADICAL; METHYLNITRONITROSOGUANIDINE; METHYLNITROSOUREA; N NITROSOPYRROLIDINE; REACTIVE OXYGEN METABOLITE; NITROSAMIDES; NITROSAMINE; NITROSO DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL STRAIN CACO 2; CHEMICAL CARCINOGENESIS; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; CONTROLLED STUDY; DNA ALKYLATION; DNA REPAIR; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; TOXICOGENETICS; CACO 2 CELL LINE; DNA MICROARRAY; ELECTRON SPIN RESONANCE; GENETIC ASSOCIATION; METABOLISM; TOXICITY;

CACO-2 CELLS; ELECTRON SPIN RESONANCE SPECTROSCOPY; GENOME-WIDE ASSOCIATION STUDY; HUMANS; NITROSAMINES; NITROSO COMPOUNDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REACTIVE OXYGEN SPECIES;

EID: 77954360443     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq121     Document Type: Article

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