Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine

Free Radical Research

Volumn 36, Issue 6, 2002, Pages 641-647

  Mikuni, Tomiko ^a   Tatsuta, Masaharu ^a  

^a OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

Gastric cancer; H2O2; MNNG; OH; Peroxynitrous acid; Xanthine oxidase

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; CATALASE; FREE RADICAL; HYDROGEN PEROXIDE; HYDROXYL RADICAL; HYPOXANTHINE; METHYLNITRONITROSOGUANIDINE; NITRATE; NITRITE; NITROGEN DIOXIDE; OXYGEN; PEROXYNITRITE; PURINE DERIVATIVE; REAGENT; SUPEROXIDE DISMUTASE; WATER; XANTHINE OXIDASE;

ARTICLE; CHEMICAL REACTION; COLORIMETRY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME MECHANISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RAT; SPIN TRAPPING; STOMACH CANCER;

CELL-FREE SYSTEM; CYCLIC N-OXIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; METHYLNITRONITROSOGUANIDINE; SPIN LABELS; STOMACH NEOPLASMS; XANTHINE OXIDASE;

EID: 0036605536     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760290029056     Document Type: Article

References (28)

1. "Tumor production in glandular stomach of rat by N-methyl-N'-nitro-N-nitrosoguanidine"
2. "Methylation of DNA by of N-methyl-n'-nitro-N-nitrosourethane and of N-methyl-n'-nitro-N-nitroso-guanidine reaction of N-methyl-n'-nitro-N-nitrosoguanidine"
3. "Interaction of N-methyl-N'-nitro-N-nitrosoguanidine with ascites hepatoma cells in vitro"
4. "Persistence of alkylated DNA bases in the Mongolian gerbil (Merious unguiculatus) following a single dose of methyl-nitrosourea"
5. "Protective effect of butylated hydroxytoluene against induction of gastric cancer by N-methyl-N'-nitrosoguanidine in Wistar rats"
6. "Scavenging effect of butylated hydroxytoluene on the production of free radicals by the reaction of hydrogen peroxide with N-methyl-N'-nitro-N-nitrosoguanidine"
7. "Oral administration of the renal carcinogen, potassium bromate, specifically produced 8-hydroxydeoxyguanosine in rat target organ DNA"
8. "Expression of stress-response and cell proliferation in renal cell carcinoma induced by oxidative stress"
9. "Reaction of cysteine with N-methyl-N-nitroso-p-toluenesulfoamide and N-methyl-N'-nitro-N-nitrosoguanidine"
10. "Hydroxyl free radical production by the reaction of N-methyl-N'-nitro-N-nitrosoguanidine with hydrogen peroxide without exposure to light"
11. "Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase"
12. "Effect of lifestyle, smoking, and diet on development of intestinal metaplasia in H. pylori-positive subjects"
13. "Oxygen radicals: Their role in selected gastrointestinal disorders"
14. "Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat"
15. "Role of oxygen radicals in ischemia-induced lesions in the cat stomach"
16. "Preparation and properties of N-methyl-N-nitroso-N'-nitroguanidine"
17. "Xanthine oxidase from bovine small intestine"
18. "Superoxide dismutase: A contaminant of bovine catalase"
19. "Spin trapping of superoxide and hydroxyl radical: Practical aspects"
20. "Production of hydroxyl free radical by reaction of hydrogen peroxide with N-methyl-N'-nitro-N-nitrosoguanidine"
21. "Evidence for the formation of hydroxyl radicals in the isomerization of pernitrous acid in aqueous solution"
22. "Inactivation of biologically active N-methyl-N-nitroso compounds in aqueous solution: Effect of various conditions of pH and illumination"
23. "Characterization of free radical generation by xanthine oxidase. Evidence for hydroxyl radical generation"
24. "Free radical formation in isolated murine keratinocytes treated with organic peroxides and its modulation by antioxidants"
25. "Signal transduction events elicited by cancer prevention compounds"
26. "Does 3,5-dibromo-4-nitrosobenzene sulphonate spin trap superoxide radiucals?"
27. "Spin trapping. Kinetics of the reaction of superoxide and hydroxyl radicals with nitrones"