Qualitative regional differences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 274, Issue 5 43-5, 1998, Pages

  DiGirolamo, M ^a   Fine, J B ^a   Tagra, K ^a   Rossmanith, R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adipose tissue composition; Cell hyperplasia; Cellular hypertrophy

Indexed keywords

ADIPOSE TISSUE; AGING; ANIMAL CELL; ARTICLE; BODY WEIGHT; CELL HYPERPLASIA; HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE DIAGNOSIS; RAT; TISSUE GROWTH;

EID: 0031831765     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.274.5.r1460     Document Type: Article

References (36)

1. Ailhaud, G. Molecular and cellular determinants of body weight regulation. In: Regulation of Body Weight: Biological and Behavioral Mechanisms, edited by C. Bouchard and G. A. Bray. New York: Wiley & Sons, 1996 p. 211-222.
2. Bailey, J. W., R. L. Barker, and R. E. Beauchene. Age-related changes in rat adipose tissue cellularity are altered by dietary restriction and exercise. J. Nutr. 123: 52-58, 1993.
3. 2a. Bartness, T. J., and T. G. Youngstrom. Sympathetic nervous system (SNS) denervation of white adipose tissue (WAT): effect on mass and celularity (Abstract). FASEB J. 11:A208, 1997.
4. Bertrand, H. A., F. T. Lynd, E. J. Masoro, and B. P. Yu. Changes in adipose mass and cellularity through the adult life of rats fed ad libitum or a life-prolonging restricted diet. J. Gerontol. A Biol. Sci. Med. Sci. 35: 827-835, 1980.
5. Björntorp, P. The regulation of adipose tissue distribution in humans. Int. J. Obes. Relat. Metab. Disord. 20: 291-302, 1996.
6. Bray, G. A. Obesity increases risk for diabetes. Int. J. Obes. Relat. Metab. Disord. 16: S13-S17, 1992.
7. Cassano, P. A., B. Rosner, P. S. Vokonas, and S. T. Weiss. Obesity and body fat distribution in relation to the incidence of non-insulin-dependent diabetes mellitus. A prospective cohort study of men in the normative aging study. Am. J. Epidemiol. 136: 1474-1486, 1992.
8. Chan, J. M., E. B. Rimm, G. A. Colditz, M. J. Stampfer, and W. C. Willett. Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care 17: 961-969, 1994.
9. Cousin, B., L. Casteilla, M. LaFontain, L. Ambid, D. Langin, M.-F. Berthault, and L. Pénicaud. Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism. Endocrinology 133: 2255-2262, 1993.
10. Crandall, D. L., and M. DiGirolamo. Hemodynamic and metabolic correlates in adipose tissue: pathophysiologic considerations. FASEB J. 4: 141-147, 1990.
11. Crandall, D. L., B. M. Goldstein, F. Huggins, and P. Cervoni. Adipocyte blood flow: influence of age, anatomic location, and dietary manipulation. Am. J. Physiol. 247 (Regulatory Integrative Comp. Physiol. 16): R46-R51, 1984.
12. DiGirolamo, M., and S. K. Fried. In vitro metabolism of adipocytes. In: Biology of the Adipocyte. Research Approaches, edited by G. J. Hausman and R. Martin. New York: Van Nostrand Reinhold, 1987, p. 120-147.
13. DiGirolamo, M., and S. Mendlinger. Role of fat cell size and number in enlargement of epididymal fat pads in three species. Am. J. Physiol. 221: 859-864, 1971.
14. DiGirolamo, M., S. Mendlinger, and J. W. Fertig. A simple method to determine fat cell size and number in four mammalian species. Am. J. Physiol. 221: 850-858, 1971.
15. DiGirolamo, M., and J. L. Owens. Water content of rat adipose tissue and isolated adipocytes in relation to cell size. Am. J. Physiol. 231: 1568-1572, 1976.
16. Dijian, P., A. K. Roncari, and C. H. Hollenberg. Influence of anatomic site and age on the replication and differentiation of rat and adipocyte precursors in culture. J. Clin. Invest. 72: 1200-1208, 1983.
17. Faust, I. M., P. R. Johnson, J. S. Stern, and J. Hirsh. Diet-induced adipocyte number increase in adult rats: a new model of obesity. Am. J. Physiol. 235 (Endocrinol. Metab. Gastrointest. Physiol. 4): E279-E286, 1978.
18. Folch, J., M. Lees, and G. H. Sloane-Stanley. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 1956: 497-508, 1957.
19. Fried, S. K., M. Lavau, and F. X. Pi-Sunyer. Variations in glucose metabolism by fat cells from three adipose depots of the rat. Metabolism 31: 876-883, 1982.
20. Geloen, A., P. E. Roy, and L. J. Bukowiecki. Regression of white adipose tissue in diabetic rats. Am. J. Physiol. 257 (Endocrinol. Metab. 20): E547-E553, 1989.
21. Hirsch, J., and P. W. Han. Cellularity of rat adipose tissue: effects of growth, starvation, and obesity. J. Lipid Res. 10: 77-82, 1969.
22. Johnson, P. R., J. S. Stern, M. R. C. Greenwood, and J. Hirsch. Adipose tissue hyperplasia and hyperinsulinemia in Zucker obese female rats: a developmental study. Metabolism 27: 1941-1954, 1978.
23. Jones, D. D., T. G. Ramsay, G. J. Hausman, and R. J. Martin. Norepinephrine inhibits rat pre-adipocyte proliferation. Int. J. Obes. 16: 349-354, 1992.
24. Kissebah, A. H., A. N. Perris, and D. J. Evan. Mechanisms associating body fat distribution to glucose intolerance and diabetes mellitus: window with a view. Acta Med. Scand. Suppl. 723: 79-89, 1988.
25. Kowalski, T. J., G. Wu, and M. Watford. Rat adipose tissue amino acid metabolism in vivo as assessed by microdialysis and arterio-venous techniques. Am. J. Physiol. 273 (Endocrinol. Metab. 36): E613-E622, 1997.
26. Lemonnier, D., J. P. Suquet, R. Aubert, P. De Gasquet, and E. Pequignot. Metabolism of the mouse made obese by a high-fat diet. Diabetes Metab. 1: 77-85, 1975.
27. Newby, F. D., M. DiGirolamo, G. A. Cotsonis, and M. H. Kutner. Model of spontaneous obesity in aging male Wistar rats. Am. J. Physiol. 259 (Regulatory Integrative Comp. Physiol. 28): R1117-R1125, 1990.
28. Newby, F. D., M. N. Sykes, and M. DiGirolamo. Regional differences in adipocyte lactate production from glucose. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E716-E722, 1988.
29. Rebuffé-Scrive, M. Neuroregulation of adipose tissue: molecular and hormonal mechanisms. Int. J. Obes. 15: 83-86, 1991.
30. Rebuffe-Scrive, M., L. Enk, N. Crona, P. Lönnroth, L. Abrahamsson, U. Smith, and P. Björntorp. Fat cell metabolism in different regions in women: effect of menstrual cycle, pregnancy, and lactation. J. Clin. Invest. 75: 1973-1976, 1985.
31. Roberts, J. L., F. M. Whittington, and M. Enser. Effects of litter size and subsequent gold-thioglucose-induced obesity on adipose tissue weight, distribution, and cellularity in male and female mice: an age study. Br. J. Nutr. 59: 519-533, 1988.
32. Svedberg, J., P. Björntorp, U. Smith, and P. Lönnroth. Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes 39: 570-574, 1990.
33. Tagra, K., J. B. Fine, R. Rossmanith, and M. DiGirolamo. Regional differences in adipose tissue (AT) growth and cellularity in a model of spontaneous obesity (Abstract). FASEB J. 11: A171, 1997.
34. Wang, H., J. L. Kirkland, and C. H. Hollenberg. Varying capacities for replication of rat adipocyte precursor clones and adipose tissue growth. J. Clin. Invest. 83: 1741-1746, 1989.
35. Warden, C. H., J. S. Fisler, S. M. Shoemaker, P. Wen, K. L. Svenson, M. J. Pace, and A. J. Lusis. Identification of four chromosomal loci determining obesity in a multifactorial mouse model. J. Clin. Invest. 95: 1545-1552, 1997.
36. Youngstrom, T. G., and T. J. Bartness. Catecholaminergic innervation of white adipose tissue in the Siberian hamster. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R744-R751, 1995.