Physical and technological parameters influencing floating properties of matrix tablets based on cellulose ethers

S.T.P. Pharma Sciences

Volumn 8, Issue 5, 1998, Pages 285-290

  Baumgartner, S ^a   Smid Korbar J ^a   Vrecer F ^b   Kristl, J ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b KRKA D D   (Slovenia)

Author keywords

Cellulose ether; Floating; Hardness; Polymer matrix tablets; Porosity; Swelling; Viscoelasticity

Indexed keywords

CELLULOSE; ETHER DERIVATIVE; HYDROXYETHYLCELLULOSE; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE;

ARTICLE; DRUG DESIGN; DRUG DOSAGE FORM; MATRIX TABLET; POROSITY; STOMACH EMPTYING; SUSTAINED RELEASE PREPARATION; VISCOELASTICITY;

EID: 0031775143     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. MOËS A.J. - Gastroretentive dosage forms. - Crit. Rev. Ther. Drug Car. Sys., 10, 143-195, 1993.
2. BANKER G.S. and RHODES C.T. Eds. - Modern Pharmaceuticals. - Marcel Dekker, New York, Basel, Hong Kong, 1996.
3. MELIA C.D. - Hydrophilic matrix sustained release systems based on polysaccharide carriers. - Crit. Rev. Ther. Drug Car. Sys., 8, 395-421, 1991.
4. ROUGE N., COLE E.T., DOELKER E. and BURI P. - Screening of potentially floating excipients for minitablets. -S.T.P. Pharma Sci., 7, 386-392, 1997.
5. KIM S. W., BAE Y. H. and OKANO T. - Hydrogels: swelling, drug loading, and release. - Pharm. Res., 9, 283-290, 1992.
6. BONFERONI M.C., ROSSI S., FERRARI F., BERTONI M., SINISTRI R. and CARAMELLA C. - Characterization of three hydroxypropylmethyl cellulose substitution types: rheological properties and dissolution behaviour. - Eur. J. Pharm. Biopharm, 41, 242-246, 1995.
7. HARIHARAN D. and PEPPAS N.A. - Modeling of water transport and solute release in physiologically sensitive gels. - J. Control. Release, 23, 123-136, 1993.
8. GEHRKE S.H. and LEE P.I. - Hydrogels for drug delivery systems. - In: Specialized Drug Delivery Systems, Manufacturing and Production Technology, Marcel Dekker, New York, Basel, 1990, pp. 332-391.
9. BONFERONI M. C., CARAMELLA C., SANGALLI M.E., CONTE U., HERNANDEZ R.M. and PEDRAZ J.L. - Rheological behaviour of hydrophilic polymers and drug release from erodible matrices. - J. Control. Release, 18, 205-212, 1992.
10. PEPPAS N. A. and COLOMBO P. - Analysis of drug behavior from swellable polymer carriers using the dimensionality index. -J. Control. Release, 45, 35-40, 1997.
11. RAJABI-SIAHBOOMI A.R., BOWTELL R.W., MANSFIELD P., DAVIES M.C. and MELIA C.D. - Structure and behaviour in hydrophilic matrix sustained release dosage forms. IV: Studies of water mobility and diffusion coefficients in the gel layer of hydroxypropylmethyl cellulose tablets using NMR imaging. -Pharm. Res., 13, 376-380, 1996.
12. LAPASIN R. and PRICL S. - Rheology of Industrial Polysaccharides, Theory and Application. - Blackie Academic and Professional, London, 1995.
13. KARADAG E., SARAYDIN D. et al. - In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-based hydrogels. - Biomaterials, 17, 67-70, 1996.