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Volumn 20, Issue 13, 2010, Pages 3982-3986

Development of potential anticancer agents that target the telomere sequence

Author keywords

Cancer; Telomerase; Telomere

Indexed keywords

ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; CYANAMIDE; DEOXYRIBONUCLEIC GUANIDINE; DNA; GUANIDINE DERIVATIVE; OLIGONUCLEOTIDE; TELOMERASE; UNCLASSIFIED DRUG;

EID: 77954310398     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.089     Document Type: Article
Times cited : (10)

References (32)
  • 24
    • 77954311109 scopus 로고    scopus 로고
    • note
    • Synthesis of 7: C-Phosphoramidate (50 mg) was added to a solution of compound 6 in DMF at 0 °C and stirred at ice bath (0 °C) for 4 h. The solid was collected by washing with dichloromethane and ether and vacuum dried.
  • 26
    • 77954311976 scopus 로고    scopus 로고
    • note
    • 4 buffer, while the ionic strength (μ) was held constant with 100 mM KCl. The absorbance of each solution at 260 nm (15 °C) was measured with a Cary 100-E2 9802310Z UV/VIS spectrometer. DNA oligomer concentrations were determined spectrophotometrically using extinction coefficients provided by the manufacturer (IDT®). The reported absorbance are an average of three experiments (±0.003)
  • 27
    • 77954313231 scopus 로고    scopus 로고
    • note
    • m values are an average of three experiments (±0.2).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.