Complexation of single strand telomere and telomerase RNA template polyanions by deoxyribonucleic guanidine (DNG) polycations: Plausible anticancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 2, 2008, Pages 665-669

  Zhang, Xiaohua ^a   Bruice, Thomas C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA; Molecular dynamics; Nucleic acid analogs

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; DEOXYRIBONUCLEIC GUANIDINE; DNA; GUANIDINE; OLIGONUCLEOTIDE; ORGANOPHOSPHATE; POLYCATION; RNA; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL DIVISION; CELL IMMORTALIZATION; CHIMERA; COMPLEX FORMATION; DNA BINDING; DRUG MECHANISM; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; NUCLEOTIDE SEQUENCE; PROTEIN CONTENT; RNA ANALYSIS; RNA BINDING; RNA STRUCTURE; TELOMERE;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; GUANIDINE; NUCLEIC ACID CONFORMATION; POLYAMINES; POLYMERS; RNA; TELOMERASE; TELOMERE; TEMPLATES, GENETIC;

EID: 38149106596     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.061     Document Type: Article

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