메뉴 건너뛰기




Volumn 291, Issue 1, 2003, Pages 11-24

B Cell receptor directs the activation of NFAT and NF-κB via distinct molecular mechanisms

Author keywords

B lymphocytes; Bruton's tyrosine kinase; Calcium; Diacylglycerol; NF B; NFAT; Phospholipase C 2; Signal transduction; Transcription factors; Transgenic knockout; X linked immunodeficiency

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; B LYMPHOCYTE RECEPTOR; BISINDOLYLMALEIMIDE; CALCIUM ION; CD5 ANTIGEN; DIACYLGLYCEROL; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL)ETHER N,N,N',N' TETRAACETIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; PROTEIN KINASE C; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; RAS PROTEIN; ROTTLERIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; VERAPAMIL;

EID: 0242270624     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00338-0     Document Type: Article
Times cited : (51)

References (73)
  • 1
    • 0033936847 scopus 로고    scopus 로고
    • Tyrosine kinase activation in the decision between growth, differentiation, and death responses initiated from the B cell antigen receptor
    • Hsueh R.C., Scheuermann R.H. Tyrosine kinase activation in the decision between growth, differentiation, and death responses initiated from the B cell antigen receptor. Adv. Immunol. 75:2000;283-316.
    • (2000) Adv. Immunol. , vol.75 , pp. 283-316
    • Hsueh, R.C.1    Scheuermann, R.H.2
  • 2
    • 0034096191 scopus 로고    scopus 로고
    • Functional dissection of BCR signaling pathways
    • Kurosaki T. Functional dissection of BCR signaling pathways. Curr. Opin. Immunol. 12:2000;276-281.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 276-281
    • Kurosaki, T.1
  • 4
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature. 381:1996;751-758.
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 6
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch R.E., Xu K., Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature. 392:1998;933-936.
    • (1998) Nature , vol.392 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 8
    • 0033959733 scopus 로고    scopus 로고
    • BLNK: Connecting Syk and Btk to calcium signals
    • Kurosaki T., Tsukada S. BLNK connecting Syk and Btk to calcium signals . Immunity. 12:2000;1-5.
    • (2000) Immunity , vol.12 , pp. 1-5
    • Kurosaki, T.1    Tsukada, S.2
  • 10
    • 0027261447 scopus 로고
    • Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes
    • Thomas J.D., Sideras P., Smith C.I., Vorechovsky I., Chapman V., Paul W.E. Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science. 261:1993;355-358.
    • (1993) Science , vol.261 , pp. 355-358
    • Thomas, J.D.1    Sideras, P.2    Smith, C.I.3    Vorechovsky, I.4    Chapman, V.5    Paul, W.E.6
  • 11
    • 0030267068 scopus 로고    scopus 로고
    • An essential role for Bruton's tyrosine kinase in the regulation of B-cell apoptosis
    • Anderson J.S., Teutsch M., Dong Z., Wortis H.H. An essential role for Bruton's tyrosine kinase in the regulation of B-cell apoptosis. Proc. Natl. Acad. Sci. USA. 93:1996;10966-10971.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10966-10971
    • Anderson, J.S.1    Teutsch, M.2    Dong, Z.3    Wortis, H.H.4
  • 15
    • 0030608960 scopus 로고    scopus 로고
    • 2+ mobilization by X-linked agammaglobulinaemia (XLA) B cells in response to ligation of the B cell receptor (BCR)
    • 2+ mobilization by X-linked agammaglobulinaemia (XLA) B cells in response to ligation of the B cell receptor (BCR). Clin. Exp. Immunol. 110:1997;386-391.
    • (1997) Clin. Exp. Immunol. , vol.110 , pp. 386-391
    • Genevier, H.C.1    Callard, R.E.2
  • 16
    • 0033712984 scopus 로고    scopus 로고
    • Xid-like phenotypes: A B cell signalosome takes shape
    • Fruman D.A., Satterthwaite A.B., Witte O.N. Xid-like phenotypes a B cell signalosome takes shape . Immunity. 13:2000;1-3.
    • (2000) Immunity , vol.13 , pp. 1-3
    • Fruman, D.A.1    Satterthwaite, A.B.2    Witte, O.N.3
  • 17
    • 0032503687 scopus 로고    scopus 로고
    • PtdIns-3,4,5-P3: A regulatory nexus between tyrosine kinases and sustained calcium signals
    • Scharenberg A.M., Kinet J.P. PtdIns-3,4,5-P3 a regulatory nexus between tyrosine kinases and sustained calcium signals . Cell. 94:1998;5-8.
    • (1998) Cell , vol.94 , pp. 5-8
    • Scharenberg, A.M.1    Kinet, J.P.2
  • 19
    • 0035914314 scopus 로고    scopus 로고
    • Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling
    • Watanabe D., Hashimoto S., Ishiai M., Matsushita M., Baba Y., Kishimoto T., Kurosaki T., Tsukada S. Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling. J. Biol. Chem. 276:2001;38595-38601.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38595-38601
    • Watanabe, D.1    Hashimoto, S.2    Ishiai, M.3    Matsushita, M.4    Baba, Y.5    Kishimoto, T.6    Kurosaki, T.7    Tsukada, S.8
  • 20
    • 0030018304 scopus 로고    scopus 로고
    • A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
    • Takata M., Kurosaki T. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J. Exp. Med. 184:1996;31-40.
    • (1996) J. Exp. Med. , vol.184 , pp. 31-40
    • Takata, M.1    Kurosaki, T.2
  • 21
    • 0028180858 scopus 로고
    • Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways
    • Takata M., Sabe H., Hata A., Inazu T., Homma Y., Nukada T., Yamamura H., Kurosaki T. Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways. EMBO J. 13:1994;1341-1349.
    • (1994) EMBO J. , vol.13 , pp. 1341-1349
    • Takata, M.1    Sabe, H.2    Hata, A.3    Inazu, T.4    Homma, Y.5    Nukada, T.6    Yamamura, H.7    Kurosaki, T.8
  • 22
    • 0028980409 scopus 로고
    • Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis [see comments]
    • Takata M., Homma Y., Kurosaki T. Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis [see comments]. J. Exp. Med. 182:1995;907-914.
    • (1995) J. Exp. Med. , vol.182 , pp. 907-914
    • Takata, M.1    Homma, Y.2    Kurosaki, T.3
  • 23
    • 0035544336 scopus 로고    scopus 로고
    • Regulation of phospholipase C-gamma2 and phosphoinositide 3-kinase pathways by adaptor proteins in B lymphocytes
    • Kurosaki T., Okada T. Regulation of phospholipase C-gamma2 and phosphoinositide 3-kinase pathways by adaptor proteins in B lymphocytes. Int. Rev. Immunol. 20:2001;697-711.
    • (2001) Int. Rev. Immunol. , vol.20 , pp. 697-711
    • Kurosaki, T.1    Okada, T.2
  • 24
    • 0028986998 scopus 로고
    • Significance of PIP2 hydrolysis and regulation of phospholipase C isozymes
    • Lee S.B., Rhee S.G. Significance of PIP2 hydrolysis and regulation of phospholipase C isozymes. Curr. Opin. Cell Biol. 7:1995;183-189.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 183-189
    • Lee, S.B.1    Rhee, S.G.2
  • 25
    • 0027397544 scopus 로고
    • Inositol trisphosphate and calcium signalling
    • Berridge M.J. Inositol trisphosphate and calcium signalling. Nature. 361:1993;315-325.
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 26
    • 0032531818 scopus 로고    scopus 로고
    • Calcium - A life and death signal
    • Berridge M.J., Bootman M.D., Lipp P. Calcium - a life and death signal. Nature. 395:1998;645-648.
    • (1998) Nature , vol.395 , pp. 645-648
    • Berridge, M.J.1    Bootman, M.D.2    Lipp, P.3
  • 27
    • 0028834424 scopus 로고
    • The elemental principles of calcium signaling
    • Bootman M.D., Berridge M.J. The elemental principles of calcium signaling. Cell. 83:1995;675-678.
    • (1995) Cell , vol.83 , pp. 675-678
    • Bootman, M.D.1    Berridge, M.J.2
  • 28
    • 0021917674 scopus 로고
    • Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores
    • Imboden J.B., Stobo J.D. Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores. J. Exp. Med. 161:1985;446-456.
    • (1985) J. Exp. Med. , vol.161 , pp. 446-456
    • Imboden, J.B.1    Stobo, J.D.2
  • 29
    • 0032055484 scopus 로고    scopus 로고
    • Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: A target for SHIP-mediated inhibitory signals
    • Scharenberg A.M., El-Hillal O., Fruman D.A., Beitz L.O., Li Z., Lin S., Gout I., Cantley L.C., Rawlings D.J., Kinet J.-P. Phosphatidylinositol-3,4,5- trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway a target for SHIP-mediated inhibitory signals . EMBO J. 17:1998;1961-1972.
    • (1998) EMBO J. , vol.17 , pp. 1961-1972
    • Scharenberg, A.M.1    El-Hillal, O.2    Fruman, D.A.3    Beitz, L.O.4    Li, Z.5    Lin, S.6    Gout, I.7    Cantley, L.C.8    Rawlings, D.J.9    Kinet, J.-P.10
  • 30
    • 0032497838 scopus 로고    scopus 로고
    • Diacylglycerol - When is it an intracellular messenger?
    • Wakelam M.J. Diacylglycerol - when is it an intracellular messenger? Biochim. Biophys. Acta. 1436:1998;117-126.
    • (1998) Biochim. Biophys. Acta. , vol.1436 , pp. 117-126
    • Wakelam, M.J.1
  • 31
    • 0036905264 scopus 로고    scopus 로고
    • Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters
    • Brose N., Rosenmund C. Move over protein kinase C, you've got company alternative cellular effectors of diacylglycerol and phorbol esters . J. Cell Sci. 115:2002;4399-4411.
    • (2002) J. Cell Sci. , vol.115 , pp. 4399-4411
    • Brose, N.1    Rosenmund, C.2
  • 33
    • 0029851762 scopus 로고    scopus 로고
    • Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
    • Timmerman L.A., Clipstone N.A., Ho S.N., Northrop J.P., Crabtree G.R. Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression. Nature. 383:1996;837-840.
    • (1996) Nature , vol.383 , pp. 837-840
    • Timmerman, L.A.1    Clipstone, N.A.2    Ho, S.N.3    Northrop, J.P.4    Crabtree, G.R.5
  • 34
    • 0033013019 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase controls a sustained calcium signal essential for B lineage development and function
    • In Process Citation
    • Rawlings D.J. Bruton's tyrosine kinase controls a sustained calcium signal essential for B lineage development and function [In Process Citation]. Clin. Immunol. 91:1999;243-253.
    • (1999) Clin. Immunol. , vol.91 , pp. 243-253
    • Rawlings, D.J.1
  • 35
    • 0035910580 scopus 로고    scopus 로고
    • Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappa B signaling pathway in B lymphocytes
    • Petro J.B., Khan W.N. Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappa B signaling pathway in B lymphocytes. J. Biol. Chem. 276:2001;1715-1719.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1715-1719
    • Petro, J.B.1    Khan, W.N.2
  • 36
    • 0034657307 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement
    • Petro J.B., Rahman S.M., Ballard D.W., Khan W.N. Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement. J. Exp. Med. 191:2000;1745-1754.
    • (2000) J. Exp. Med. , vol.191 , pp. 1745-1754
    • Petro, J.B.1    Rahman, S.M.2    Ballard, D.W.3    Khan, W.N.4
  • 37
    • 0034657235 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation
    • Bajpai U.D., Zhang K., Teutsch M., Sen R., Wortis H.H. Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation. J. Exp. Med. 191:2000;1735-1744.
    • (2000) J. Exp. Med. , vol.191 , pp. 1735-1744
    • Bajpai, U.D.1    Zhang, K.2    Teutsch, M.3    Sen, R.4    Wortis, H.H.5
  • 38
    • 0024833664 scopus 로고
    • Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation
    • Emmel E.A., Verweij C.L., Durand D.B., Higgins K.M., Lacy E., Crabtree G. Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science. 246:1989;1617-1620.
    • (1989) Science , vol.246 , pp. 1617-1620
    • Emmel, E.A.1    Verweij, C.L.2    Durand, D.B.3    Higgins, K.M.4    Lacy, E.5    Crabtree, G.6
  • 39
    • 0024591783 scopus 로고
    • Differences in DNA sequence specifically among MHC class II X box binding proteins
    • Boothby M., Liou H.-C., Glimcher L.H. Differences in DNA sequence specifically among MHC class II X box binding proteins. J. Immunol. 142:1989;1005-1014.
    • (1989) J. Immunol. , vol.142 , pp. 1005-1014
    • Boothby, M.1    Liou, H.-C.2    Glimcher, L.H.3
  • 40
    • 0030949834 scopus 로고    scopus 로고
    • Expression of NFAT-family proteins in normal human T cells
    • Lyakh L., Ghosh P., Rice N.R. Expression of NFAT-family proteins in normal human T cells. Mol. Cell Biol. 17:1997;2475-2484.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 2475-2484
    • Lyakh, L.1    Ghosh, P.2    Rice, N.R.3
  • 41
    • 0037021452 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase targets NF-kappaB to the bcl-x promoter via a mechanism involving phospholipase C-gamma2 following B cell antigen receptor engagement
    • Petro J.B., Castro I., Lowe J., Khan W.N. Bruton's tyrosine kinase targets NF-kappaB to the bcl-x promoter via a mechanism involving phospholipase C-gamma2 following B cell antigen receptor engagement. FEBS Lett. 532:2002;57-60.
    • (2002) FEBS Lett. , vol.532 , pp. 57-60
    • Petro, J.B.1    Castro, I.2    Lowe, J.3    Khan, W.N.4
  • 42
    • 0033785222 scopus 로고    scopus 로고
    • Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells
    • Antony P., Kanfer J.N., Freysz L. Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells. Neurochem. Res. 25:2000;1073-1082.
    • (2000) Neurochem. Res. , vol.25 , pp. 1073-1082
    • Antony, P.1    Kanfer, J.N.2    Freysz, L.3
  • 43
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from the animal tissues
    • Folch-Pi J., Lees M., Sloan-Stanley G. A simple method for the isolation and purification of total lipids from the animal tissues. J. Biol. Chem. 226:1957;497-509.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch-Pi, J.1    Lees, M.2    Sloan-Stanley, G.3
  • 44
    • 0035976851 scopus 로고    scopus 로고
    • Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA-N-1 neuroblastoma cells: A key role for diacylglycerol
    • Antony P., Farooqui A.A., Horrocks L.A., Freysz L. Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA-N-1 neuroblastoma cells a key role for diacylglycerol . FEBS Lett. 509:2001;115-118.
    • (2001) FEBS Lett. , vol.509 , pp. 115-118
    • Antony, P.1    Farooqui, A.A.2    Horrocks, L.A.3    Freysz, L.4
  • 45
    • 0023627427 scopus 로고
    • Thin-layer chromatography of human platelet phospholipids with fatty acid analysis
    • Leray C., Pelletier X., Hemmendinger S., Cazenave J.P. Thin-layer chromatography of human platelet phospholipids with fatty acid analysis. J. Chromatogr. 420:1987;411-416.
    • (1987) J. Chromatogr. , vol.420 , pp. 411-416
    • Leray, C.1    Pelletier, X.2    Hemmendinger, S.3    Cazenave, J.P.4
  • 46
    • 2242446203 scopus 로고    scopus 로고
    • Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling
    • Petro J.B., Gerstein R.M., Lowe J., Carter R.S., Shinners N., Khan W.N. Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling. J. Biol. Chem. 277:2002;48009-48019.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48009-48019
    • Petro, J.B.1    Gerstein, R.M.2    Lowe, J.3    Carter, R.S.4    Shinners, N.5    Khan, W.N.6
  • 48
    • 0035794018 scopus 로고    scopus 로고
    • Hematopoietic cell-specific adapter proteins, SLP-76 and BLNK, effectively activate NF-AT as well as NF-kappaB by Syk and Tec PTKs in non-lymphoid cell lines
    • Yamamoto T., Matsuda T., Junicho A., Kishi H., Yoshimura A., Muraguchi A. Hematopoietic cell-specific adapter proteins, SLP-76 and BLNK, effectively activate NF-AT as well as NF-kappaB by Syk and Tec PTKs in non-lymphoid cell lines. FEBS Lett. 491:2001;272-278.
    • (2001) FEBS Lett. , vol.491 , pp. 272-278
    • Yamamoto, T.1    Matsuda, T.2    Junicho, A.3    Kishi, H.4    Yoshimura, A.5    Muraguchi, A.6
  • 50
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao A., Luo C., Hogan P.G. Transcription factors of the NFAT family regulation and function . Annu. Rev. Immunol. 15:1997;707-747.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 51
    • 0037124307 scopus 로고    scopus 로고
    • Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha
    • Saijo K., Mecklenbrauker I., Santana A., Leitger M., Schmedt C., Tarakhovsky A. Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha. J. Exp. Med. 195:2002;1647-1652.
    • (2002) J. Exp. Med. , vol.195 , pp. 1647-1652
    • Saijo, K.1    Mecklenbrauker, I.2    Santana, A.3    Leitger, M.4    Schmedt, C.5    Tarakhovsky, A.6
  • 53
    • 0028450096 scopus 로고
    • Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4
    • Choi M.S., Brines R.D., Holman M.J., Klaus G.G. Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. Immunity. 1:1994;179-187.
    • (1994) Immunity , vol.1 , pp. 179-187
    • Choi, M.S.1    Brines, R.D.2    Holman, M.J.3    Klaus, G.G.4
  • 55
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies S.P., Reddy H., Caivano M., Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:2000;95-105.
    • (2000) Biochem. J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 56
    • 0037177813 scopus 로고    scopus 로고
    • Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727
    • Uddin S., Sassano A., Deb D.K., Verma A., Majchrzak B., Rahman A., Malik A.B., Fish E.N., Platanias L.C. Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J. Biol. Chem. 277:2002;14408-14416.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14408-14416
    • Uddin, S.1    Sassano, A.2    Deb, D.K.3    Verma, A.4    Majchrzak, B.5    Rahman, A.6    Malik, A.B.7    Fish, E.N.8    Platanias, L.C.9
  • 57
    • 0034724201 scopus 로고    scopus 로고
    • NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
    • Coudronniere N., Villalba M., Englund N., Altman A. NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc. Natl. Acad. Sci. USA. 97:2000;3394-3399.
    • (2000) Proc. Natl. Acad. Sci. USA. , vol.97 , pp. 3394-3399
    • Coudronniere, N.1    Villalba, M.2    Englund, N.3    Altman, A.4
  • 58
    • 0034194092 scopus 로고    scopus 로고
    • Identification of PKC-isoform-specific biological actions using pharmacological approaches
    • Way K.J., Chou E., King G.L. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol. Sci. 21:2000;181-187.
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 181-187
    • Way, K.J.1    Chou, E.2    King, G.L.3
  • 59
    • 0033822263 scopus 로고    scopus 로고
    • Immunobiology of the immature B cell: Plasticity in the B-cell antigen receptor-induced response fine tunes negative selection
    • King L.B., Monroe J.G. Immunobiology of the immature B cell plasticity in the B-cell antigen receptor-induced response fine tunes negative selection . Immunol. Rev. 176:2000;86-104.
    • (2000) Immunol. Rev. , vol.176 , pp. 86-104
    • King, L.B.1    Monroe, J.G.2
  • 60
    • 0031802722 scopus 로고    scopus 로고
    • An NFAT-dependent enhancer is necessary for anti-IgM-mediated induction of murine CD5 expression in primary splenic B cells
    • Berland R., Wortis H.H. An NFAT-dependent enhancer is necessary for anti-IgM-mediated induction of murine CD5 expression in primary splenic B cells. J. Immunol. 161:1998;277-285.
    • (1998) J. Immunol. , vol.161 , pp. 277-285
    • Berland, R.1    Wortis, H.H.2
  • 62
    • 0028915307 scopus 로고
    • Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin
    • Teutsch M., Higer M., Wang D., Wortis H.W. Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin. Int. Immunol. 7:1995;381-392.
    • (1995) Int. Immunol. , vol.7 , pp. 381-392
    • Teutsch, M.1    Higer, M.2    Wang, D.3    Wortis, H.W.4
  • 63
    • 0035350807 scopus 로고    scopus 로고
    • Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT
    • Aifantis I., Gounari F., Scorrano L., Borowski C., von Boehmer H. Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT. Nat. Immunol. 2:2001;403-409.
    • (2001) Nat. Immunol. , vol.2 , pp. 403-409
    • Aifantis, I.1    Gounari, F.2    Scorrano, L.3    Borowski, C.4    Von Boehmer, H.5
  • 65
    • 0035129248 scopus 로고    scopus 로고
    • NFATc1 and NFATc2 together control both T and B cell activation and differentiation
    • Peng S.L., Gerth A.J., Ranger A.M., Glimcher L.H. NFATc1 and NFATc2 together control both T and B cell activation and differentiation. Immunity. 14:2001;13-20.
    • (2001) Immunity , vol.14 , pp. 13-20
    • Peng, S.L.1    Gerth, A.J.2    Ranger, A.M.3    Glimcher, L.H.4
  • 66
    • 0018147907 scopus 로고
    • T-independent responses in B cell-defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus
    • Mond J.J., Scher I., Mosier D.E., Baese M., Paul W.E. T-independent responses in B cell-defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus. Eur. J. Immunol. 8:1978;459-463.
    • (1978) Eur. J. Immunol. , vol.8 , pp. 459-463
    • Mond, J.J.1    Scher, I.2    Mosier, D.E.3    Baese, M.4    Paul, W.E.5
  • 67
    • 0017714803 scopus 로고
    • The ontogeny of thymic independent antibody responses in vitro in normal mice and mice with an X-linked B cell defect
    • Mosier D.E., Mond J.J., Goldings E.A. The ontogeny of thymic independent antibody responses in vitro in normal mice and mice with an X-linked B cell defect. J. Immunol. 119:1977;1874-1878.
    • (1977) J. Immunol. , vol.119 , pp. 1874-1878
    • Mosier, D.E.1    Mond, J.J.2    Goldings, E.A.3
  • 68
    • 0027286351 scopus 로고
    • Persistent calcium elevation correlates with the induction of surface immunoglobulin-mediated B cell DNA synthesis
    • Yamada H., June C.H., Finkelman F., Brunswick M., Ring M.S., Lees A., Mond J.J. Persistent calcium elevation correlates with the induction of surface immunoglobulin-mediated B cell DNA synthesis. J. Exp. Med. 177:1993;1613-1621.
    • (1993) J. Exp. Med. , vol.177 , pp. 1613-1621
    • Yamada, H.1    June, C.H.2    Finkelman, F.3    Brunswick, M.4    Ring, M.S.5    Lees, A.6    Mond, J.J.7
  • 69
    • 0020334971 scopus 로고
    • Stimulation of the murine immune system by anti-IgD antibodies: A polyclonal model of B-lymphocyte activation by a thymus dependent antigen
    • Finkelman F.D., Muul L.M., Yaffe L., Scher I., Mond J.J., Kessler S.W., Ryan J., Kung J.T., Metcalf E.S. Stimulation of the murine immune system by anti-IgD antibodies a polyclonal model of B-lymphocyte activation by a thymus dependent antigen . Ann. NY Acad. Sci. 399:1982;316-328.
    • (1982) Ann. NY Acad. Sci. , vol.399 , pp. 316-328
    • Finkelman, F.D.1    Muul, L.M.2    Yaffe, L.3    Scher, I.4    Mond, J.J.5    Kessler, S.W.6    Ryan, J.7    Kung, J.T.8    Metcalf, E.S.9
  • 70
    • 0020562929 scopus 로고
    • Polyclonal activation of the murine immune system by an antibody to IgD. IV. In vivo activation of B lymphocytes from immune defective CBA/N mice
    • Muul L.M., Scher I., Mond J.J., Finkelman F.D. Polyclonal activation of the murine immune system by an antibody to IgD. IV. In vivo activation of B lymphocytes from immune defective CBA/N mice. J. Immunol. 131:1983;2226-2231.
    • (1983) J. Immunol. , vol.131 , pp. 2226-2231
    • Muul, L.M.1    Scher, I.2    Mond, J.J.3    Finkelman, F.D.4
  • 72
    • 0033044091 scopus 로고    scopus 로고
    • An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets
    • Bendall H.H., Sikes M.L., Ballard D.W., Oltz E.M. An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets. Mol. Immunol. 36:1999;187-195.
    • (1999) Mol. Immunol. , vol.36 , pp. 187-195
    • Bendall, H.H.1    Sikes, M.L.2    Ballard, D.W.3    Oltz, E.M.4
  • 73
    • 0037090084 scopus 로고    scopus 로고
    • I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function
    • Ren H., Schmalstieg A., van Oers N.S., Gaynor R.B. I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function. J. Immunol. 168:2002;3721-3731.
    • (2002) J. Immunol. , vol.168 , pp. 3721-3731
    • Ren, H.1    Schmalstieg, A.2    Van Oers, N.S.3    Gaynor, R.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.